High anxiety in clinically healthy patients and increased QT dispersion: A meta-analysis

European Journal of Preventive Cardiology

Volumn 21, Issue 12, 2014, Pages 1568-1574

  Kelmanson, Igor A ^a  

^a International University for Family and Child   (Russian Federation)

Author keywords

Anxiety; arrhythmias; meta analysis; QT dispersion; repolarization

Indexed keywords

ANXIETY; ANXIETY DISORDER; ARTICLE; CONFIDENCE INTERVAL; HEART RATE; HUMAN; QT DISPERSION; ACTION POTENTIAL; ADULT; ARRHYTHMIAS, CARDIAC; COMPLICATION; FEMALE; HEART MUSCLE CONDUCTION SYSTEM; MALE; META ANALYSIS; MIDDLE AGED; PATHOPHYSIOLOGY; REFRACTORY PERIOD; RISK ASSESSMENT; RISK FACTOR; YOUNG ADULT;

ACTION POTENTIALS; ADULT; ANXIETY; ARRHYTHMIAS, CARDIAC; FEMALE; HEART CONDUCTION SYSTEM; HEART RATE; HUMANS; MALE; MIDDLE AGED; REFRACTORY PERIOD, ELECTROPHYSIOLOGICAL; RISK ASSESSMENT; RISK FACTORS; YOUNG ADULT;

EID: 84911893643     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1177/2047487313501613     Document Type: Article

References (64)

1. Saksena S, Camm AJ Electrophysiological disorders of the heart. 2 nd ed. Philadelphia, PA: Elsevier/Saunders, 2012, pp. 1458-1458. Philadelphia, PA: Elsevier/Saunders ; 2012: 1458-1458.
2. Issa ZF, Miller JM, Zipes DP Clinical arrhythmology and electrophysiology: A companion to Braunwald's heart disease. 2 nd ed. Philadelphia, PA: Elsevier/Saunders, 2012, pp. 502-502. Philadelphia, PA: Elsevier/Saunders ; 2012: 502-502.
3. Siscovick DS, Raghunathan TE, Rautaharju P, et al. Clinically silent electrocardiographic abnormalities and risk of primary cardiac arrest among hypertensive patients. Circulation. 1996 ; 94: 1329-1333
4. Day CP, McComb JM, Campbell RW. QT dispersion: An indication of arrhythmia risk in patients with long QT intervals. Br Heart J. 1990 ; 63: 342-344
5. Malik M, Batchvarov VN. Measurement, interpretation and clinical potential of QT dispersion. J Am Coll Cardiol. 2000 ; 36: 1749-1766
6. Kuo CS, Munakata K, Reddy CP, et al. Characteristics and possible mechanism of ventricular arrhythmia dependent on the dispersion of action potential durations. Circulation. 1983 ; 67: 1356-1367
7. Zabel M, Portnoy S, Franz MR. Electrocardiographic indexes of dispersion of ventricular repolarization: An isolated heart validation study. J Am Coll Cardiol. 1995 ; 25: 746-752
8. Higham PD, Hilton DJ, Aitcheson JD. QT dispersion: A measure of underlying dispersion of ventricular recovery?. Eur Heart J. 1993 ; 14: 86-86
9. Zabel M, Lichtlen PR, Haverich A, et al. Comparison of ECG variables of dispersion of ventricular repolarization with direct myocardial repolarization measurements in the human heart. J Cardiovasc Electrophysiol. 1998 ; 9: 1279-1284
10. Surawicz B. Will QT dispersion play a role in clinical decision-making?. J Cardiovasc Electrophysiol. 1996 ; 7: 777-784
11. Statters DJ, Malik M, Ward DE, et al. QT dispersion: Problems of methodology and clinical significance. J Cardiovasc Electrophysiol. 1994 ; 5: 672-685
12. Galinier M, Balanescu S, Fourcade J, et al. Prognostic value of ventricular arrhythmias in systemic hypertension. J Hypertens. 1997 ; 15: 1779-1783
13. Cin VG, Celik M, Ulucan S. QT dispersion ratio in patients with unstable angina pectoris (a new risk factor?). Clin Cardiol. 1997 ; 20: 533-535
14. Barr CS, Naas A, Freeman M, et al. QT dispersion and sudden unexpected death in chronic heart failure. Lancet. 1994 ; 343: 327-329
15. Galinier M, Vialette JC, Fourcade J, et al. QT interval dispersion as a predictor of arrhythmic events in congestive heart failure. Importance of aetiology. Eur Heart J. 1998 ; 19: 1054-1062
16. Sánchez Bonomo AM, Cavalcanti Ferreira de Araujo TC Cardiac arrhythmias - new considerations. Breijo-Marquez FR, ed. Rijeka, Croatia: InTech ; 2012: 307-324.
17. Lampert R, Joska T, Burg MM, et al. Emotional and physical precipitants of ventricular arrhythmia. Circulation. 2002 ; 106: 1800-1805
18. Barlow DH Anxiety and its disorders: The nature and treatment of anxiety and panic. 2 nd ed. New York: Guilford Press, 2002, pp. 704-704. New York: Guilford Press ; 2002: 704-704.
19. DiTomasso RA, Gosch EA Comparative treatments for anxiety disorders. New York: Springer ; 2002: 344-344.
20. Anxiety disorders. Diagnostic and statistical manual of mental disorders. 4 th ed. Washington, DC: American Psychiatric Association, 1994, pp. 435-436. Washington, DC: American Psychiatric Association ; 1994: 435-436.
21. Argyropoulos SV, Bell CJ, Nutt DJ. Brain function in social anxiety disorder. Psychiatr Clin North Am. 2001 ; 24: 707-722
22. Cornwell BR, Johnson L, Berardi L, et al. Anticipation of public speaking in virtual reality reveals a relationship between trait social anxiety and startle reactivity. Biol Psychiatry. 2006 ; 59: 664-666
23. Piccirillo G, Elvira S, Bucca C, et al. Abnormal passive head-up tilt test in subjects with symptoms of anxiety power spectral analysis study of heart rate and blood pressure. Int J Cardiol. 1997 ; 60: 121-131
24. Laude D, Girard A, Consoli S, et al. Anger expression and cardiovascular reactivity to mental stress: A spectral analysis approach. Clin Exp Hypertens. 1997 ; 19: 901-911
25. Hayward C. Psychiatric illness and cardiovascular disease risk. Epidemiol Rev. 1995 ; 17: 129-138
26. Yayou K, Annen Y, Kuwahara M, et al. Studies on the autonomic nervous function in Tsukuba emotional rats - with special reference to their cardiac function. J Vet Med Sci. 1993 ; 55: 1017-1023
27. Friedman BH, Thayer JF, Borkovec TD, et al. Autonomic characteristics of nonclinical panic and blood phobia. Biol Psychiatry. 1993 ; 34: 298-310
28. Beauchaine T. Vagal tone, development, and Gray's motivational theory: Toward an integrated model of autonomic nervous system functioning in psychopathology. Dev Psychopathol. 2001 ; 13: 183-214
29. Sevy S, Papadimitriou GN, Surmont DW, et al. Noradrenergic function in generalized anxiety disorder, major depressive disorder, and healthy subjects. Biol Psychiatry. 1989 ; 25: 141-152
30. Garvey MJ, Noyes R, Woodman C, et al. The association of urinary 5-hydroxyindoleacetic acid and vanillylmandelic acid in patients with generalized anxiety. Neuropsychobiology. 1995 ; 31: 6-9
31. Bystritsky A, Craske M, Maidenberg E, et al. Autonomic reactivity of panic patients during a CO2 inhalation procedure. Depress Anxiety. 2000 ; 11: 15-26
32. Gorman JM, Sloan RP. Heart rate variability in depressive and anxiety disorders. Am Heart J. 2000 ; 140: 77-83
33. Albert CM, Chae CU, Rexrode KM, et al. Phobic anxiety and risk of coronary heart disease and sudden cardiac death among women. Circulation. 2005 ; 111: 480-487
34. Kawachi I, Sparrow D, Vokonas PS, et al. Symptoms of anxiety and risk of coronary heart disease. The Normative Aging Study. Circulation. 1994 ; 90: 2225-2229
35. Kawachi I, Colditz GA, Ascherio A, et al. Prospective study of phobic anxiety and risk of coronary heart disease in men. Circulation. 1994 ; 89: 1992-1997
36. Schwartz PJ. Idiopathic long QT syndrome: Progress and questions. Am Heart J. 1985 ; 109: 399-411
37. Kubzansky LD, Kawachi I, Spiro A, 3rd, et al. Is worrying bad for your heart? A prospective study of worry and coronary heart disease in the Normative Aging Study. Circulation. 1997 ; 95: 818-824
38. Damen NL, Pelle AJ, Boersma E, et al. Reduced positive affect (anhedonia) is independently associated with 7-year mortality in patients treated with percutaneous coronary intervention: Results from the RESEARCH registry. Eur J Prev Cardiol. 2013 ; 20: 127-134
39. Hedges LV, Olkin I Statistical methods for meta-analysis. Orlando, FL: Academic Press ; 1985: 369-369.
40. Borenstein M Introduction to meta-analysis. Chichester, UK: John Wiley & Sons ; 2009: 421-421.
41. Borenstein M, Hedges L, Higgins J, et al Comprehensive meta-analysis version 2. Englewood, NJ: Biostat ; 2005: 104-104.
42. Piccirillo G, Viola E, Bucca C, et al. QT interval dispersion and autonomic modulation in subjects with anxiety. J Lab Clin Med. 1999 ; 133: 461-468
43. Piccirillo G, Cacciafesta M, Lionetti M, et al. Influence of age, the autonomic nervous system and anxiety on QT-interval variability. Clin Sci (Lond). 2001 ; 101: 429-438
44. Nahshoni E, Gur S, Marom S, et al. QT dispersion in patients with social phobia. J Affect Disord. 2004 ; 78: 21-26
45. Uyarel H, Okmen E, Cobanoglu N, et al. Effects of anxiety on QT dispersion in healthy young men. Acta Cardiol. 2006 ; 61: 83-87
46. Kwon YD, Lim SW, Oh KS. Higher QT dispersion in patients with Social Anxiety Disorder. Korean J Biol Psychiatry. 2010 ; 17: 44-48
47. Atmaca M, Yavuzkir M, Izci F, et al. QT wave dispersion in patients with panic disorder. Neurosci Bull. 2012 ; 28: 247-252
48. Cohen J Statistical power analysis for the behavioral sciences. 2 nd ed. Hillsdale, NJ: L Erlbaum Associates, 1988, pp. 567-567. Hillsdale, NJ: L Erlbaum Associates ; 1988: 567-567.
49. Kautzner J, Yi G, Camm AJ, et al. Short- and long-term reproducibility of QT, QTc, and QT dispersion measurement in healthy subjects. Pacing Clin Electrophysiol. 1994 ; 17: 928-937
50. Malik M, Camm AJ. Mystery of QTc interval dispersion. Am J Cardiol. 1997 ; 79: 785-787
51. Kawachi I, Sparrow D, Vokonas PS, et al. Decreased heart rate variability in men with phobic anxiety (data from the Normative Aging Study). Am J Cardiol. 1995 ; 75: 882-885
52. Morris A, Baker B, Devins GM, et al. Prevalence of panic disorder in cardiac outpatients. Can J Psychiatry. 1997 ; 42: 185-190
53. Guler N, Bilge M, Eryonucu B, et al. The effect of electroconvulsive therapy on QT dispersion. Acta Cardiol. 1998 ; 53: 355-358
54. Nahshoni E, Aizenberg D, Strasberg B, et al. QT dispersion in the surface electrocardiogram in elderly patients with major depression. J Affect Disord. 2000 ; 60: 197-200
55. Piccirillo G, Viola E, Nocco M, et al. Autonomic modulation and QT interval dispersion in hypertensive subjects with anxiety. Hypertension. 1999 ; 34: 242-246
56. Kawachi I, Colditz GA, Ascherio A, et al. Prospective study of phobic anxiety and risk of coronary heart disease in men. Circulation. 1994 ; 89: 1992-1997
57. Ishida S, Nakagawa M, Fujino T, et al. Circadian variation of QT interval dispersion: Correlation with heart rate variability. J Electrocardiol. 1997 ; 30: 205-210
58. Okin PM, Devereux RB, Howard BV, et al. Assessment of QT interval and QT dispersion for prediction of all-cause and cardiovascular mortality in American Indians (The Strong Heart Study). Circulation. 2000 ; 101: 61-66
59. Yeragani VK, Pohl R, Jampala VC, et al. Increased QT variability in patients with panic disorder and depression. Psychiatry Res. 2000 ; 93: 225-235
60. Rechlin T, Weis M, Ott C, et al. Alterations of autonomic cardiac control in anorexia nervosa. Biol Psychiatry. 1998 ; 43: 358-363
61. Yeragani VK, Tancer M, Uhde T. Heart rate and QT interval variability: Abnormal alpha-2 adrenergic function in patients with panic disorder. Psychiatry Res. 2003 ; 121: 185-196
62. Yeragani VK, Rao KA, Pohl R, et al. Heart rate and QT variability in children with anxiety disorders: A preliminary report. Depress Anxiety. 2001 ; 13: 72-77
63. Baumert M, Lambert GW, Dawood T, et al. QT interval variability and cardiac norepinephrine spillover in patients with depression and panic disorder. Am J Physiol Heart Circ Physiol. 2008 ; 295: H962 - H968
64. Malik M, Bigger JT, Camm AJ, et al. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996 ; 17: 354-381