Severe preeclampsia: Association of genes polymorphisms and maternal cytokines production in Brazilian population

Cytokine

Volumn 71, Issue 2, 2015, Pages 232-237

  Pinheiro, Melina B ^a,b   Gomes, Karina B ^a   Ronda, Carla R S C ^c   Guimarães, Gabrielle G ^c   Freitas, Letícia G ^a   Teixeira Carvalho, Andréa ^d   Martins Filho, Olindo Assis ^d   Dusse, Luci M ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO JOÃO DEL REI   (Brazil)

^c Simile Instituto de Imunologia Aplicada   (Brazil)

^d INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Cytokine gene polymorphism; Cytokine levels; Inflammation; Preeclampsia

Indexed keywords

ADENINE; CYTOSINE; GAMMA INTERFERON; GUANINE; INTERLEUKIN 10; INTERLEUKIN 6; THYMINE; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ARTICLE; BLOOD LEVEL; BRAZIL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMETRY; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NUCLEIC ACID BASE SUBSTITUTION; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PREGNANT WOMAN; ADULT; BLOOD; CASE CONTROL STUDY; FLOW CYTOMETRY; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; PATHOLOGY; PREGNANCY; SEVERITY OF ILLNESS INDEX; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

ADULT; BRAZIL; CASE-CONTROL STUDIES; CYTOKINES; FEMALE; FLOW CYTOMETRY; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-6; POLYMORPHISM, SINGLE NUCLEOTIDE; PRE-ECLAMPSIA; PREGNANCY; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84911455447     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2014.10.021     Document Type: Article

References (59)

1. ACOG practice bulletin Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 2002, 2002(77):67-75.
2. Ahn H., Park J., Gilman-Sachs A., Kwak-Kim J. Immunologic characteristics of preeclampsia, a comprehensive review. Am J Reprod Immunol 2011, 65:377-394.
3. Redman C.W., Sargent I.L. Immunology of pre-eclampsia. Am J Reprod Immunol 2010, 63:534-543.
4. Redman C.W.G., Sargent I.L. Pre-eclampsia, the Placenta and the maternal systemic inflammatory response-a review. Placenta 2003, 24:S21-S27.
5. Laresgoiti-Servitje E., Gomez-Lopez N., Olson D.M. An immunological insight into the origins of pre-eclampsia. Hum Reprod Update 2010, 16:510-524.
6. Darmochwal-Kolarz D., Leszczynska-Gorzelak B., Rolinski J., Oleszczuk J. T helper 1- and T helper 2-type cytokine imbalance in pregnant women with pre-eclampsia. Eur J Obstet Gynecol Reprod Biol 1999, 86:165-170.
7. Daher S., de Arruda Geraldes Denardi K., Blotta M.H., Mamoni R.L., Reck A.P., Camano L., et al. Cytokines in recurrent pregnancy loss. J Reprod Immunol 2004, 62:151-157.
8. Moore K.W., de Waal Malefyt R., Coffman R.L., O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 2001, 19:683-765.
9. Hennessy A., Pilmore H.L., Simmons L.A., Painter D.M. A deficiency of placental IL-10 in preeclampsia. J Immunol 1999, 163:3491-3495.
10. Wilczynski J.R., Tchorzewski H., Banasik M., Glowacka E., Wieczorek A., Lewkowicz P., et al. Lymphocyte subset distribution and cytokine secretion in third trimester decidua in normal pregnancy and preeclampsia. Eur J Obstet Gynecol Reprod Biol 2003, 109:8-15.
11. Azizieh F., Raghupathy R., Makhseed M. Maternal cytokine production patterns in women with pre-eclampsia. Am J Reprod Immunol 2005, 54:30-37.
12. Omu A.E., Al-Azemi M.K., Al-Qattan F., Al-Yatama M. Connection between human leucocyte antigens D region and T helper cytokines in preeclampsia. Arch Gynecol Obstet 2004, 269:79-84.
13. Saito S., Umekage H., Sakamoto Y., Sakai M., Tanebe K., Sasaki Y., et al. Increased T-helper-1-type immunity and decreased T-helper-2-type immunity in patients with preeclampsia. Am J Reprod Immunol 1999, 41:297-306.
14. Yoneyama Y., Suzuki S., Sawa R., Yoneyama K., Power G.G., Araki T. Relation between adenosine and T-helper 1/T-helper 2 imbalance in women with preeclampsia. Obstet Gynecol 2002, 99:641-646.
15. Haimovici F., Hill J.A., Anderson D.J. The effects of soluble products of activated lymphocytes and macrophages on blastocyst implantation events in vitro. Biol Reprod 1991, 44:69-75.
16. Clark D.A., Chaouat G., Arck P.C., Mittruecker H.W., Levy G.A. Cytokine-dependent abortion in CBA x DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase [correction of prothombinase]. J Immunol 1998, 160:545-549.
17. Yui J., Garcia-Lloret M., Wegmann T.G., Guilbert L.J. Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts. Placenta 1994, 15:819-835.
18. Canto-Cetina T., Canizales-Quinteros S., de la Chesnaye E., Coral-Vazquez R., Mendez J.P., Canto P. Analysis of C-850T and G-308A polymorphisms of the tumor necrosis factor-alpha gene in Maya-Mestizo women with preeclampsia. Hypertens Pregnancy 2007, 26:283-291.
19. Daher S., Sass N., Oliveira L.G., Mattar R. Cytokine genotyping in preeclampsia. Am J Reprod Immunol 2006, 55:130-135.
20. de Groot C.J., Jansen M.W., Bertina R.M., Schonkeren J.J., Helmerhorst F.M., Huizinga T.W. Interleukin 10-2849AA genotype protects against pre-eclampsia. Genes Immun 2004, 5:313-314.
21. de Lima T.H., Sass N., Mattar R., Moron A.F., Torloni M.R., Franchim C.S., et al. Cytokine gene polymorphisms in preeclampsia and eclampsia. Hypertens Res 2009, 32:565-569.
22. Haggerty C.L., Ferrell R.E., Hubel C.A., Markovic N., Harger G., Ness R.B. Association between allelic variants in cytokine genes and preeclampsia. Am J Obstet Gynecol 2005, 193:209-215.
23. Kaiser T., Grehan M., Brennecke S.P., Moses E.K. Association of the TNF2 allele with eclampsia. Gynecol Obstet Invest 2004, 57:204-209.
24. Kamali-Sarvestani E., Kiany S., Gharesi-Fard B., Robati M. Association study of IL-10 and IFN-gamma gene polymorphisms in Iranian women with preeclampsia. J Reprod Immunol 2006, 72:118-126.
25. Kim S.Y., Lim J.H., Park S.Y., Yang J.H., Kim M.Y., Kim M.H., et al. Transforming growth factor-beta 1 gene polymorphisms in Korean patients with pre-eclampsia. Am J Reprod Immunol 2010, 63:291-298.
26. Mirahmadian M., Kalantar F., Heidari G., Safdarian L., Mansouri R., Amirzargar A.A. Association of tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in Iranian patients with pre-eclampsia. Am J Reprod Immunol 2008, 60:179-185.
27. Pazarbas A., Kasap M.I., Güzel A.I., Kasapa H., Özbakir B., et al. Polymorphisms in the tumor necrosis factor-alpha gene in Turkish women with pre-eclampsia and eclampsia. Acta Med Okayama 2007, 61:153-160.
28. Saarela T., Hiltunen M., Helisalmi S., Heinonen S., Laakso M. Polymorphisms of interleukin-6, hepatic lipase and calpain-10 genes, and preeclampsia. Eur J Obstet Gynecol Reprod Biol 2006, 128:175-179.
29. Stonek F., Metzenbauer M., Hafner E., Philipp K., Tempfer C. Interleukin 6-174 G/C promoter polymorphism and pregnancy complications: results of a prospective cohort study in 1626 pregnant women. Am J Reprod Immunol 2008, 59:347-351.
30. Stonek F., Metzenbauer M., Hafner E., Philipp K., Tempfer C. Interleukin-10-1082 G/A promoter polymorphism and pregnancy complications: results of a prospective cohort study in 1616 pregnant women. Acta Obstet Gynecol Scand 2008, 87:430-433.
31. Vural P., Degirmencioglu S., Saral N.Y., Demirkan A., Akgul C., Yildirim G., et al. Tumor necrosis factor alpha, interleukin-6 and interleukin-10 polymorphisms in preeclampsia. J Obstet Gynaecol Res 2010, 36:64-71.
32. Hoffmann S.C., Stanley E.M., Cox E.D., Craighead N., Dimercurio B.S., Koziol D.E., et al. Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28 stimulated peripheral blood lymphocytes. Transplantation 2001, 72:1444-1450.
33. Pravica V., Asderakis A., Perrey C., Hajeer A., Sinnott P.J., Hutchinson I.V. In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene. Eur J Immunogenet 1999, 26:1-3.
34. Turner D.M., Williams D.M., Sankaran D., Lazarus M., Sinnott P.J., Hutchinson I.V. An Investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997, 24:1-8.
35. Wilson A.G., de Vries N., Pociot F., di Giovine F.S., van der Putte L.B., Duff G.W. An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles. J Exp Med 1993, 177:557-560.
36. Bombell S., McGuire W. Tumour necrosis factor (-308A) polymorphism in pre-eclampsia: meta-analysis of 16 case-control studies. Aust N Z J Obstet Gynaecol 2008, 48:547-551.
37. Dizon-Townson D.S., Major H., Ward K. A promoter mutation in the tumor necrosis factor-alpha gene is not associated with preeclampsia. J Reprod Immunol 1998, 38:55-61.
38. Freeman D.J., McManus F., Brown E.A., Cherry L., Norrie J., Ramsay J.E., et al. Short- and long-term changes in plasma inflammatory markers associated with preeclampsia. Hypertension 2004, 44:708-714.
39. Livingston J.C., Park V., Barton J.R., Elfering S., Haddad B., Mabie W.C., et al. Lack of association of severe preeclampsia with maternal and fetal mutant alleles for tumor necrosis factor alpha and lymphotoxin alpha genes and plasma tumor necrosis factor alpha levels. Am J Obstet Gynecol 2001, 184:1273-1277.
40. Stanczuk G.A., McCoy M.J., Hutchinson I.V., Sibanda E.N. The genetic predisposition to produce high levels of TGF-beta1 impacts on the severity of eclampsia/pre-eclampsia. Acta Obstet Gynecol Scand 2007, 86:903-908.
41. Stonek F., Bentz E.K., Hafner E., Metzenbauer M., Philipp K., Hefler L.A., et al. A tumor necrosis factor-alpha promoter polymorphism and pregnancy complications: results of a prospective cohort study in 1652 pregnant women. Reprod Sci 2007, 14:425-429.
42. Stonek F., Hafner E., Metzenbauer M., Katharina S., Stumpflen I., Schneeberger C., et al. Absence of an association of tumor necrosis factor (TNF)-alpha G308A, interleukin-6 (IL-6) G174C and interleukin-10 (IL-10) G1082A polymorphism in women with preeclampsia. J Reprod Immunol 2008, 77:85-90.
43. Xie C., Yao M.Z., Liu J.B., Xiong L.K. A meta-analysis of tumor necrosis factor-alpha, interleukin-6, and interleukin-10 in preeclampsia. Cytokine 2011, 56:550-559.
44. Rein D.T., Breidenbach M., Honscheid B., Friebe-Hoffmann U., Engel H., Gohring U.J., et al. Preeclamptic women are deficient of interleukin-10 as assessed by cytokine release of trophoblast cells in vitro. Cytokine 2003, 23:119-125.
45. Papanicolaou D.A., Wilder R.L., Manolagas S.C., Chrousos G.P. The pathophysiologic roles of interleukin-6 in human disease. Ann Intern Med 1998, 128:127-137.
46. Chen Q., Stone P., Ching L.M., Chamley L. A role for interleukin-6 in spreading endothelial cell activation after phagocytosis of necrotic trophoblastic material: implications for the pathogenesis of pre-eclampsia. J Pathol 2009, 217:122-130.
47. Chen Q., Stone P.R., McCowan L.M., Chamley L.W. Phagocytosis of necrotic but not apoptotic trophoblasts induces endothelial cell activation. Hypertension 2006, 47:116-121.
48. Molvarec A., Szarka A., Walentin S., Beko G., Karadi I., Prohaszka Z., et al. Serum leptin levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in normal pregnancy and preeclampsia. Reprod Biol Endocrinol 2011, 9:124.
49. Sharma D., Singh A., Trivedi S.S., Bhattacharjee J. Intergenotypic variation of nitric oxide and inflammatory markers in preeclampsia: a pilot study in a North Indian population. Hum Immunol 2011, 72:436-439.
50. Sharma D., Singh A., Trivedi S.S., Bhattacharjee J. Role of endothelin and inflammatory cytokines in pre-eclampsia - a pilot North Indian study. Am J Reprod Immunol 2011, 65:428-432.
51. Szarka A., Rigo J., Lazar L., Beko G., Molvarec A. Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol 2010, 11:59.
52. Jonsson Y., Ruber M., Matthiesen L., Berg G., Nieminen K., Sharma S., et al. Cytokine mapping of sera from women with preeclampsia and normal pregnancies. J Reprod Immunol 2006, 70:83-91.
53. Sutherland G.R., Baker E., Callen D.F., Hyland V.J., Wong G., Clark S., et al. Interleukin 4 is at 5q31 and interleukin 6 is at 7p15. Hum Genet 1988, 79:335-337.
54. Hunt J.S., Soares M.J., Lei M.G., Smith R.N., Wheaton D., Atherton R.A., et al. Products of lipopolysaccharide-activated macrophages (tumor necrosis factor-alpha, transforming growth factor-beta) but not lipopolysaccharide modify DNA synthesis by rat trophoblast cells exhibiting the 80-kDa lipopolysaccharide-binding protein. J Immunol 1989, 143:1606-1613.
55. Nawroth P.P., Stern D.M. Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J Exp Med 1986, 163:740-745.
56. Stark J.M. Pre-eclampsia and cytokine induced oxidative stress. Br J Obstet Gynaecol 1993, 100:105-109.
57. Mansouri R., Akbari F., Vodjgani M., Mahboudi F., Kalantar F., Mirahmadian M. Serum cytokines profiles in Iranian patients with preeclampsia. Iran J Immunol 2007, 4:179-185.
58. Krasnow J.S., Tollerud D.J., Naus G., DeLoia J.A. Endometrial Th2 cytokine expression throughout the menstrual cycle and early pregnancy. Hum Reprod 1996, 11:1747-1754.
59. Dudley D.J., Hunter C., Mitchell M.D., Varner M.W. Clinical value of amniotic fluid interleukin-6 determinations in the management of preterm labour. Br J Obstet Gynaecol 1994, 101:592-597.