14-3-3σ is an independent prognostic biomarker for gastric cancer and is associated with apoptosis and proliferation in gastric cancer

Oncology Letters

Volumn 9, Issue 1, 2015, Pages 290-294

  Li, Yi Liang ^a   Liu, Lihua ^b   Xiao, Yang ^a   Zeng, Tao ^c   Zeng, Chao ^c  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

^c GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

14 3 3 ; Apoptosis; Immunohistochemistry; Prognosis; Proliferation

Indexed keywords

KI 67 ANTIGEN; PROTEIN BCL 2; STRATIFIN;

ADULT; APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROTEIN EXPRESSION; STOMACH CANCER; TISSUE MICROARRAY; TUMOR INVASION; TUMOR VOLUME;

EID: 84911452557     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2014.2676     Document Type: Article

References (24)

1. Correa P: Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 52: 6735-6740, 1992.
2. Hara T, Ooi A, Kobayashi M, et al: Amplification of c-myc, K-sam, and c-met in gastric cancers: detection by fluorescence in situ hybridization. Lab Invest 78: 1143-1153, 1998.
3. Yu J, Miehlke S, Ebert MP, et al: Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives. Cancer 88: 1801-1805, 2000.
4. Nakatsuru S, Yanagisawa A, Ichii S, et al: Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma. Hum Mol Genet 1: 559-563, 1992.
5. Kim JH, Takahashi T, Chiba I, et al: Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines. J Natl Cancer Inst 83: 938-943, 1991.
6. Park K, Kim SJ, Bang YJ, et al: Genetic changes in the transforming growth factor beta (TGF-β) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-β. Proc Natl Acad Sci USA 91: 8772-8776, 1994.
7. Xu HW, Ren F, Yu YM and Cai CZ: Runx3 expression in lymph nodes with metastasis is associated with the outcome of gastric cancer patients. Oncol Lett 2: 1275-1279, 2011.
8. Lalle M, Leptourgidou F, Camerini S, et al: Interkingdom complementation reveals structural conservation and functional divergence of 14-3-3 proteins. PLoS One 11: e78090, 2013.
9. Rosenquist M, Alsterfjord M, Larsson C and Sommarin M: Data mining the Arabidopsis genome reveals fifteen 14-3-3 genes. Expression is demonstrated for two out of five novel genes. Plant Physiol 127: 142-149, 2001.
10. Chan TA, Hermeking H, Lengauer C, et al : 14-3-3σ is required to prevent mitotic catastrophe after DNA damage. Nature 401: 616-620, 1999.
11. Laronga C, Yang HY, Neal C and Lee MH: Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression. J Biol Chem 275: 23106-23112, 2000.
12. Xiao T, Mi W, Li M, et al: Analyzed the molecular interaction network of tumor suppressor gene 14-3-3 sigma in lung cancer cell based on stable isotope labeling by amino acids in cell culture technology. Zhonghua Yu Fang Yi Xue Za Zhi 47: 752-756, 2013 (In Chinese).
13. Evren S, Dermen A, Lockwood G, et al : mTOR-RAPTOR and 14-3-3σ immunohistochemical expression in high grade prostatic intraepithelial neoplasia and prostatic adenocarcinomas: a tissue microarray study. J Clin Pathol 64: 683-688, 2011.
14. Zhang Z, Zhang G and Kong C: High expression of Cdc25B and low expression of 14-3-3σ is associated with the development and poor prognosis in urothelial carcinoma of bladder. Tumour Biol 35: 2503-2512.
15. Liu S, Howell P, Ren S, et al The 14-3-3σ gene promoter is methylated in both human melanocytes and melanoma. BMC Cancer 27: 162, 2009.
16. Xie D, Sham JS, Zeng WF, et al Heterogeneous expression and association of β-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray. Int J Cancer 107: 896-902, 2003.
17. Ide M, Nakajima T, Asao T and Kuwano H: Inactivation of 14-3-3σ by hypermethylation is a rare event in colorectal cancers and its expression may correlate with cell cycle maintenance at the invasion front. Cancer Lett 207: 241-249, 2004.
18. Iwata N, Yamamoto H, Sasaki S, et al Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 σ gene in human hepatocellular carcinoma. Oncogene 19: 5298-5302, 2000.
19. Nakamura Y, Oshima K, Naoi Y, et al 14-3-3σ expression is associated with poor pathological complete response to neoadjuvant chemotherapy in human breast cancers. Breast Cancer Res Treat 134: 229-236, 2012.
20. Mhawech-Fauceglia P, Herrmann FR, Anderws C, et al: 14-3-3σ expression and prognostic value in patients with epithelial ovarian carcinoma: a high throughput tissue microarray analysis. Eur J Surg Oncol 35: 763-767, 2009.
21. Erovic BM, Pelzmann M, Grasl MCh, et al: Mcl-1, vascular endothelial growth factor-R2, and 14-3-3σ expression might predict primary response against radiotherapy and chemotherapy in patients with locally advanced squamous cell carcinomas of the head and neck. Clin Cancer Res 11: 8632-8636, 2005.
22. Li Z, Dong Z, Myer D, et al Role of 14-3-3σ in poor prognosis and in radiation and drug resistance of human pancreatic cancers. BMC Cancer 10: 598, 2010.
23. Perathoner A, Pirkebner D, Brandacher G, et al : 14-3-3σ expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients. Clin Cancer Res 11: 3274-3279, 2005.
24. Guweidhi A, Kleeff J, Giese N, et al Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis. Carcinogenesis 25: 1575-1585, 2004.