Procalcitonin as a predictor of moderate to severe acute respiratory distress syndrome after cardiac surgery with cardiopulmonary bypass: A study protocol for a prospective cohort study

BMJ Open

Volumn 4, Issue 10, 2014, Pages

  Chen, Han ^a   Cheng, Zhang Bo ^a   Yu, Rong Guo ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; C REACTIVE PROTEIN; CEFAZOLIN; HEPARIN; PROCALCITONIN; BRAIN NATRIURETIC PEPTIDE; CALCITONIN; PEPTIDE FRAGMENT; PRO-BRAIN NATRIURETIC PEPTIDE (1-76); PROTEIN PRECURSOR;

ADULT RESPIRATORY DISTRESS SYNDROME; ANTIBIOTIC PROPHYLAXIS; ANTICOAGULANT THERAPY; ARTICLE; BACTERIAL INFECTION; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; DISEASE SEVERITY; ELECTIVE SURGERY; FOLLOW UP; HEART SURGERY; HORMONE BLOOD LEVEL; HOSPITAL ADMISSION; HUMAN; INCIDENCE; LEUKOCYTE COUNT; MEMBRANE OXYGENATOR; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PERIOPERATIVE PERIOD; PEROPERATIVE COMPLICATION; POSTOPERATIVE COMPLICATION; PREDICTION; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; ROLLER PUMP; BLOOD; SEVERITY OF ILLNESS INDEX;

CALCITONIN; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; COHORT STUDIES; HUMANS; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; PROTEIN PRECURSORS; RESPIRATORY DISTRESS SYNDROME, ADULT; SEVERITY OF ILLNESS INDEX;

EID: 84911442707     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2014-006344     Document Type: Article

References (18)

1. Milot J, Perron J, Lacasse Y, et al. Incidence and predictors of ARDS after cardiac surgery. Chest 2001; 119: 884-8.
2. Christenson JT, Aeberhard JM, Badel P, et al. Adult respiratory distress syndrome after cardiac surgery. Cardiovasc Surg 1996; 4: 15-21.
3. Kaul TK, Fields BL, Riggins LS, et al. Adult respiratory distress syndrome following cardiopulmonary bypass: incidence, prophylaxis and management. J Cardiovasc Surg 1998; 39: 777-81.
4. Stephens RS, Shah AS, Whitman GJ. Lung injury and acute respiratory distress syndrome after cardiac surgery. Ann Thorac Surg 2013; 95: 1122-9.
5. Weissman C. Pulmonary complications after cardiac surgery. Semin Cardiothorac Vasc Anesth 2004; 8: 185-211.
6. Rubenfeld GD, Caldwell E, Peabody E, et al. Incidence and outcomes of acute lung injury. N Engl J Med 2005; 353: 1685-93.
7. Prat C, Ricart P, Ruyra X, et al. Serum concentrations of procalcitonin after cardiac surgery. J Card Surg 2008; 23: 627-32.
8. Hennein HA, Ebba H, Rodriguez JL, et al. Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization. J Thorac Cardiovasc Surg 1994; 108: 626-35.
9. Rocke DA, Gaffin SL, Wells MT, et al. Endotoxemia associated with cardiopulmonary bypass. J Thorac Cardiovasc Surg 1987; 93: 832-7.
10. Franke A, Lante W, Fackeldey V, et al. Pro-inflammatory cytokines after different kinds of cardio-thoracic surgical procedures: is what we see what we know? Eur J Cardiothorac Surg 2005; 28: 569-75.
11. Assicot M, Bohuon C, Gendrel D, et al. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993; 341: 515-18.
12. Reinhart K, Karzai W, Meisner M. Procalcitonin as a marker of the systemic inflammatory response to infection. Intensive Care Med 2000; 26: 1193-200.
13. Kallel S, Abid M, Jarraya A, et al. [Kinetics, diagnostic and prognostic value of procalcitonin after cardiac surgery]. Ann Biol Clin (Paris) 2012; 70: 567-80.
14. Dorge H, Schondube FA, Dorge P, et al. Procalcitonin is a valuable prognostic marker in cardiac surgery but not specific for infection. Thorac Cardiovasc Surg 2003; 51: 322-6.
15. Kallel S, Jmel W, Jarraya A, et al. The role of procalcitonin and N-terminal pro-B-type natriuretic peptide in predicting outcome after cardiac surgery. Perfusion 2012; 27: 504-11.
16. AHA medical/scientific statement. 1994 revisions to classification of functional capacity and objective assessment of patients with diseases of the heart. Circulation 1994; 90: 644-5.
17. Gaies MG, Gurney JG, Yen AH, et al. Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass. Pediatr Crit Care Med 2010; 11: 234-8.
18. Ranieri VM, Rubenfeld GD, Thompson BT, et al. ARDS Definition Task Force. Acute respiratory distress syndrome: the Berlin Definition. JAMA 2012; 307: 2526-33.