A high copy number of FCGR3B is associated with psoriasis vulgaris in Han Chinese

Dermatology

Volumn 229, Issue 2, 2014, Pages 70-75

  Wu, Yumei ^a   Zhang, Zhou ^b   Tao, Liming ^b,d   Chen, Guoliang ^c   Liu, Fatao ^d   Wang, Ting ^d   Xue, Feng ^b   Chen, Yingwei ^a   He, Lin ^b   Zheng, Jie ^b   Liu, Yun ^c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Copy number; FCGR3B; Han Chinese; Psoriasis vulgaris

Indexed keywords

ADULT; AGED; ARTICLE; CASE CONTROL STUDY; COMPARATIVE STUDY; CONTROLLED STUDY; COPY NUMBER VARIATION; ETHNIC GROUP; FEMALE; GENOTYPE; HAN CHINESE; HUMAN; MAJOR CLINICAL STUDY; MALE; PSORIASIS VULGARIS; SAMPLE SIZE; CHINA; EPIDEMIOLOGY; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; PREVALENCE; PSORIASIS; REAL TIME POLYMERASE CHAIN REACTION;

DNA; FC RECEPTOR; FCGR3B PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN;

ADULT; CHINA; DNA; DNA COPY NUMBER VARIATIONS; ETHNIC GROUPS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GPI-LINKED PROTEINS; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PSORIASIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, IGG;

EID: 84911440846     PISSN: 10188665     EISSN: 14219832     Source Type: Journal    
DOI: 10.1159/000360160     Document Type: Article

References (16)

1. Yip SY: The prevalence of psoriasis in the mongoloid race. J Am Acad Dermatol 1984; 10: 965-968.
2. Perera GK, Di Meglio P, Nestle FO: Psoriasis. Annu Rev Pathol 2012; 7: 385-422.
3. Girirajan S, Campbell CD, Eichler EE: Human copy number variation and complex genetic disease. Annu Rev Genet 2011; 45: 203-226.
4. Schaschl H, Aitman TJ, Vyse TJ: Copy number variation in the human genome and its implication in autoimmunity. Clin Exp Immunol 2009; 156: 12-16.
5. Graf SW, Lester S, Nossent JC, Hill CL, Proudman SM, Lee A, Rischmueller M: Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis. Arthritis Res Ther 2012; 14:R28.
6. Robinson JI, Carr IM, Cooper DL, Rashid LH, Martin SG, Emery P, Isaacs JD, Barton A; BRAGGSS, Wilson AG, Barrett JH, Morgan AW: Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis. Hum Mutat 2012; 33: 741-749.
7. Nossent JC, Rischmueller M, Lester S: Low copy number of the fc-γ receptor 3B gene FCGR3B is a risk factor for primary Sjogren's syndrome. J Rheumatol 2012; 39: 2142-2147.
8. Mamtani M, Anaya JM, He W, Ahuja SK: Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases. Genes Immun 2010; 11: 155-160.
9. Zhao A, Xiang YQ, Xu JW, Li QL, Wang L, Xing QH, Zhang Z, Liu Y, Feng GY, He L, Zhao XZ: Lack of support for association between the copy number variants in the FCGR locus and schizophrenia: a case control study. Neurosci Lett 2012; 522: 85-91.
10. Lv J, Yang Y, Zhou X, Yu L, Li R, Hou P, Zhang H: FCGR3B copy number variation is not associated with lupus nephritis in a Chinese population. Lupus 2010; 19: 158-161.
11. Willcocks LC, Lyons PA, Clatworthy MR, Robinson JI, Yang W, Newland SA, Plagnol V, McGovern NN, Condliffe AM, Chilvers ER, Adu D, Jolly EC, Watts R, Lau YL, Morgan AW, Nash G, Smith KG: Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake. J Exp Med 2008; 205: 1573-1582.
12. Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, Smith J, Mangion J, Roberton- Lowe C, Marshall AJ, Petretto E, Hodges MD, Bhangal G, Patel SG, Sheehan-Rooney K, Duda M, Cook PR, Evans DJ, Domin J, Flint J, Boyle JJ, Pusey CD, Cook HT: Copy number polymorphism in FCGR3 predisposes to glomerulonephritis in rats and humans. Nature 2006; 439: 851-855.
13. Zhou XJ, Lv JC, Bu DF, Yu L, Yang YR, Zhao J, Cui Z, Yang R, Zhao MH, Zhang H: Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease. Int Immunol 2010; 22: 45-51.
14. Niederer HA, Willcocks LC, Rayner TF, Yang W, Lau YL, Williams TN, Scott JA, Urban BC, Peshu N, Dunstan SJ, Hien TT, Phu NH, Padyukov L, Gunnarsson I, Svenungsson E, Savage CO, Watts RA, Lyons PA, Clayton DG, Smith KG: Copy number, linkage disequilibrium and disease association in the FCGR locus. Hum Mol Genet 2010; 19: 3282-3294.
15. Skilbeck CA, Lu X, Sheikh S, Savage CO, Nash GB: Capture of flowing human neutrophils by immobilised immunoglobulin: roles of Fc-receptors CD16 and CD32. Cell Immunol 2006; 241: 26-31.
16. Breunis WB, van Mirre E, Geissler J, Laddach N, Wolbink G, van der Schoot E, de Haas M, de Boer M, Roos D, Kuijpers TW: Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B. Hum Mutat 2009; 30:E640-E650.