Association of daunorubicin to a lipid nanoemulsion that binds to low-density lipoprotein receptors enhances the antitumour action and decreases the toxicity of the drug in melanoma-bearing mice

The Journal of pharmacy and pharmacology

Volumn 66, Issue 12, 2014, Pages 1698-1709

  Contente, Thaís C ^a   Kretzer, Iara F ^a   Filippin Monteiro, Fabiola B ^a   Maria, Durvanei A ^a   Maranhão, Raul C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

cancer treatment; daunorubicin; drug delivery; low density lipoprotein receptors; nanoparticles

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; CHOLESTEROL; DAUNORUBICIN; DRUG CARRIER; EMULSION; LOW DENSITY LIPOPROTEIN RECEPTOR; N-OLEYL-DAUNORUBICIN; NANOMATERIAL; OLEIC ACID; PROTEIN BINDING;

ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CANCER TRANSPLANTATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG STABILITY; EMULSION; MALE; MELANOMA, EXPERIMENTAL; METABOLISM; PARTICLE SIZE; PATHOLOGY; TOXICITY TESTING; TUMOR CELL LINE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL SURVIVAL; CHOLESTEROL; DAUNORUBICIN; DRUG CARRIERS; DRUG STABILITY; EMULSIONS; MALE; MELANOMA, EXPERIMENTAL; MICE, INBRED C57BL; MOLECULAR STRUCTURE; NANOSTRUCTURES; NEOPLASM TRANSPLANTATION; OLEIC ACIDS; PARTICLE SIZE; PROTEIN BINDING; RECEPTORS, LDL; TOXICITY TESTS, ACUTE;

EID: 84911421505     PISSN: None     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12296     Document Type: Article

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