The network of micrornas, Transcription factors, Target genes and host genes in human renal cell carcinoma

Oncology Letters

Volumn 9, Issue 1, 2015, Pages 498-506

  Song, Chenglu ^a   Xu, Zhiwen ^a   Jin, Yue ^a   Zhu, Minghui ^a   Wang, Kunhao ^a   Wang, Ning ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Host genes; MicroRNA; Network; Renal cell carcinoma; Target genes; Transcription factors

Indexed keywords

MICRORNA; PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL NEURAL NETWORK; DOWN REGULATION; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; INFORMATION PROCESSING; KIDNEY CARCINOMA; PATHOGENESIS; PROMOTER REGION; TUMOR SUPPRESSOR GENE;

EID: 84911407543     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2014.2683     Document Type: Article

References (18)

1. Mulders PF, Brouwers AH, Hulsbergen-van der Kaa CA, van Lin EN, Osanto S and de Mulder PH: Guideline ‘Renal cell carcinoma’. Ned Tijdschr Geneeskd 152: 376-380, 2008 (In Dutch).
2. Bruyère F, Hovens CM, Marson MN, d'Arcier BF, Costello AJ, Watier H, Linassier C and Ohresser M: VEGF polymorphisms are associated with an increasing risk of developing renal cell carcinoma. J Urol 184: 1273-1278, 2010.
3. Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, Ueno K, Yamamura S, Zaman MS, Khatri G, Chen Y, Saini S, Majid S, Deng G, Ishii N and Dahiya R: Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. Int J Cancer 128: 1793-1803, 2011.
4. Hobert O: Gene regulation by transcription factors and microRNAs. Science 319: 1785-1786, 2008.
5. Rodriguez A, Griffiths-Jones S, Ashurst JL and Bradley A: Identification of mammalian microRNA host genes and transcription units. Genome Res 14: 1902-1910, 2004.
6. Baskerville S and Bartel DP: Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 11: 241-247, 2005.
7. Papadopoulos GL, Reczko M, Simossis VA, Sethupathy P and Hatzigeorgiou AG: The database of experimentally supported targets: a functional update of TarBase. Nucleic Acids Res 37: D155-D158, 2009.
8. Wang J, Lu M, Qiu C and Cui Q: TransmiR: a transcription factor-microRNA regulation database. Nucleic Acids Res 38: D119-D122, 2009.
9. Jiang Q, Wang Y, Hao Y, et al: miR2Disease: a manually curated database for microRNA deregulation in human disease. Nucleic Acids Res 37: D98-D104, 2009.
10. Wirsing A, Senkel S, Klein-Hitpass L and Ryffel GU: A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites. PloS One 6: e27438, 2011.
11. Baytekin F, Tuna B, Mungan U, Aslan G and Yorukoglu K: Significance of P-glycoprotein, p53, and survivin expression in renal cell carcinoma. Urol Oncol 29: 502-507, 2011.
12. Petrella BL and Brinckerhoff CE: PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma. Cancer Biol Ther 8: 1389-1401, 2009.
13. Harada K, Miyake H, Kusuda Y and Fujisawa M: Expression of epithelial-mesenchymal transition markers in renal cell carcinoma: impact on prognostic outcomes in patients undergoing radical nephrectomy. BJU Int 110: E1131-E1137, 2012.
14. Cai H, Sun L, Cui L, Cao Q, Qin C, Zhang G, Mao X, Wang M, Zhang Z, Shao P and Yin C: A functional insertion/deletion polymorphism (-94 ins/del ATTG) in the promoter region of the NFKB1 gene is related to the risk of renal cell carcinoma. Urol Int 91: 206-212, 2013.
15. Postigo AA and Dean DC: Independent repressor domains in ZEB regulate muscle and T-cell differentiation. Mol Cell Biol 19: 7961-7971, 1999.
16. Liu H, Brannon AR, Reddy AR, Alexe G, Seiler MW, Arreola A, Oza JH, Yao M, Juan D, Liou LS, Ganesan S, Levine AJ, Rathmell WK and Bhanot GV: Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell renal cell carcinoma. BMC Syst Biol 4: 51, 2010.
17. Kompier LC, Lurkin I, van der Aa MN, van Rhijn BW, van der Kwast TH and Zwarthoff EC: FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy. PloS One 5: e13821, 2010.
18. Dey N, Das F, Ghosh-Choudhury N, Mandal CC, Parekh DJ, Block K, Kasinath BS, Abboud HE and Choudhury GG: microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion. PloS One 7: e37366, 2012.