A missense mutation in melanocortin 1 receptor is associated with the red coat colour in donkeys

Animal Genetics

Volumn 45, Issue 6, 2014, Pages 878-880

  Abitbol, M ^a,b   Legrand, R ^a,b   Tiret, L ^a,b  

^a UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^b ECOLE NATIONALE VÉTÉRINAIRE D ALFORT   (France)

Author keywords

chestnut; melanocortin 1 receptor; melanocyte; miniature donkey; Normand donkey

Indexed keywords

EQUUS ASINUS;

MELANOCORTIN 1 RECEPTOR;

ALLELE; ANIMAL; EQUIDAE; GENETICS; GENOTYPE; HAIR COLOR; MISSENSE MUTATION; RECESSIVE GENE;

ALLELES; ANIMALS; EQUIDAE; GENES, RECESSIVE; GENOTYPE; HAIR COLOR; MUTATION, MISSENSE; RECEPTOR, MELANOCORTIN, TYPE 1;

EID: 84911389340     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/age.12207     Document Type: Article

References (7)

1. Bromberg Y., Overton J., Vaisse C., Leibel R.L., &, Rost B., (2009) In silico mutagenesis: a case study of the melanocortin 4 receptor. FASEB Jou 23, 3059-69.
2. Katritch V., Cherezov V., &, Stevens R.C., (2012) Diversity and modularity of G protein-coupled receptor structures. Trends in Pharmacological Sciences 33, 17-27.
3. Moukhametzianov R., Warne T., Edwards P.C., Serrano-Vega M.J., Leslie A.G., Tate C.G., &, Schertler G.F., (2011) Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America 108, 8228-32.
4. Park J.H., Scheerer P., Hofmann K.P., Choe H.W., &, Ernst O.P., (2008) Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature 454, 183-7.
5. Wang Z.Q., &, Tao Y.X., (2013) Functions of the third intracellular loop of the human melanocortin-3 receptor. Current Pharmaceutical Design 19, 4831-8.
6. Yang Y., (2011) Structure, function and regulation of the melanocortin receptors. European Journal of Pharmacology 660, 125-30.
7. Yang F., &, Tao Y.X., (2012) Functional characterization of nine novel naturally occurring human melanocortin-3 receptor mutations. Biochimica et Biophysica Acta 1822, 1752-61.