Neonatal pain management

Saudi Journal of Anaesthesia

Volumn 8, Issue 5, 2014, Pages S89-S97

  Bhalla, Tarun ^a,b   Shepherd, Ed ^a,b   Tobias, Joseph ^a,b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Neonatal anesthesia; neonatal pain management; opioids; pain scores

Indexed keywords

ALFENTANIL; BILIRUBIN; BUPIVACAINE; FENTANYL; HALOTHANE; IBUPROFEN; INDOMETACIN; KETOROLAC; LIDOCAINE; MORPHINE; NALOXONE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; OXYGEN; PARACETAMOL; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; REMIFENTANIL; ROPIVACAINE; SUFENTANIL;

ABDOMINAL SURGERY; ABSENCE OF SIDE EFFECTS; ANALGESIA; ARTICLE; BLEEDING; BLOOD PRESSURE MEASUREMENT; BODY POSTURE; BRAIN HEMORRHAGE; CHILD DEVELOPMENT; CLINICAL OBSERVATION; CONGENITAL HEART DISEASE; CONTINUOUS INFUSION; CRYING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE REDUCTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG OVERDOSE; ENZYME INHIBITION; EPIDURAL ANESTHESIA; FACIAL EXPRESSION; GLOMERULUS FILTRATION RATE; HEART RATE; HEART SURGERY; HUMAN; INFANT; INSOMNIA; KIDNEY FAILURE; LOADING DRUG DOSE; NECROTIZING ENTEROCOLITIS; NEONATAL HYPERBILIRUBINEMIA; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NEWBORN CARE; NOCICEPTION; OXYGEN SATURATION; PAIN; PAIN ASSESSMENT; PATENT DUCTUS ARTERIOSUS; POSTOPERATIVE PAIN; PREMATURITY; PROSTAGLANDIN SYNTHESIS INHIBITION; RATING SCALE; RECOMMENDED DRUG DOSE; REGIONAL ANESTHESIA; RESPIRATION DEPRESSION; SIDE EFFECT; STIMULUS RESPONSE; THORAX WALL DEFECT; THORAX WALL RIGIDITY; THROMBOCYTE DYSFUNCTION; UNSPECIFIED SIDE EFFECT; VITAL SIGN;

EID: 84911387687     PISSN: 1658354X     EISSN: 09753125     Source Type: Journal    
DOI: 10.4103/1658-354X.144085     Document Type: Article

References (74)

1. Mather L, Mackie J. The incidence of postoperative pain in children. Pain 1983;15:271-82.
2. Mancuso T, Burns J. Ethical concerns in the management of pain in the neonate. Paediatr Anaesth 2009;19:953-7.
3. Peters JW, Schouw R, Anand KJ, van Dijk M, Duivenvoorden HJ, Tibboel D. Does neonatal surgery lead to increased pain sensitivity in later childhood? Pain 2005;114:444-54.
4. Bartocci M, Bergqvist LL, Lagercrantz H, Anand KJ. Pain activates cortical areas in the preterm newborn brain. Pain 2006;122:109-17.
5. Anand KJ, Runeson B, Jacobson B. Gastric suction at birth associated with long-Term risk for functional intestinal disorders in later life. J Pediatr 2004;144:449-54.
6. Hoar PF, Stone JG, Faltas AN, Bendixen HH, Head RJ, Berkowitz BA. Hemodynamic and adrenergic responses to anesthesia and operation for myocardial revascularization. J Thorac Cardiovasc Surg 1980;80:242-8.
7. Scheinin B, Scheinin M, Asantila R, Lindberg R, Viinamaki O. Sympatho-Adrenal and pituitary hormone responses during and immediately after thoracic surgery-modulation by four different pain treatments. Acta Anaesthesiol Scand 1987;31:762-7.
8. Anand KJ, Hansen DD, Hickey PR. Hormonal-metabolic stress responses in neonates undergoing cardiac surgery. Anesthesiology 1990;73:661-70.
9. Anand KJ, Hickey PR. Halothane-morphine compared with high-dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery. N Engl J Med 1992;326:1-9.
10. Akca O, Melischek M, Scheck T, Hellwagner K, Arkilic CF, Kurz A, et al. Postoperative pain and subcutaneous oxygen tension. Lancet 1999;354:41-2.
11. Ranger M, Johnston CC, Anand KJ. Current controversies regarding pain assessment in neonates. Semin Perinatol 2007;31:283-8.
12. Hall RW. Anesthesia and analgesia in the NICU. Clin Perinatol 2012;39:239-54.
13. Craig KD, Whitfield MF, Grunau RV, Linton J, Hadjistavropoulos HD. Pain in the preterm neonate: Behavioural and physiological indices. Pain 1993;52:287-99.
14. Stevens BJ, Johnston CC. Physiological responses of premature infants to a painful stimulus. Nurs Res 1994;43:226-31.
15. Johnston CC, Stevens BJ, Yang F, Horton L. Differential response to pain by very premature neonates. Pain 1995;61:471-9.
16. Stevens B, Johnston C, Petryshen P, Taddio A. Premature Infant Pain Profile: Development and initial validation. Clin J Pain 1996;12:13-22.
17. Morton NS. Pain assessment in children. Paediatr Anaesth 1997;7:267-72.
18. Buttner W, Finke W. Analysis of behavioural and physiological parameters for the assessment of postoperative analgesic demand in newborns, infants and young children: A comprehensive report on seven consecutive studies. Paediatr Anaesth 2000;10:303-18.
19. Taddio A, Nulman I, Koren BS, Stevens B, Koren G. A revised measure of acute pain in infants. J Pain Symptom Manage 1995;10:456-63.
20. Stevens B, Johnston C, Petryshen P, Taddio A. Premature Infant Pain Profile: Development and initial validation. Clin J Pain 1996;12:13-22.
21. Cong X, McGrath JM, Cusson RM, Zhang D. Pain assessment and measurement in neonates: An updated review. Adv Neonatal Care 2013;13:379-95.
22. Krechel SW, Bildner J. CRIES: A new neonatal postoperative pain measurement score. Initial testing of validity and reliability. Paediatr Anaesth 1995;5:53-61.
23. Birmingham PK, Tobin MJ, Henthorn TK, Fisher DM, Berkelhamer MC, Smith FA, et al. Twenty-four-hour pharmacokinetics of rectal acetaminophen in children: An old drug with new recommendations. Anesthesiology 1997;87:244-52.
24. Birmingham PK, Tobin MJ, Fisher DM, Henthorn TK, Hall SC, Cote CJ. Initial and subsequent dosing of rectal acetaminophen in children: A 24-hour pharmacokinetic study of new dose recommendations. Anesthesiology 2001;94:385-9.
25. Anderson BJ, van Lingen RA, Hansen TG, Lin YC, Holford NH. Acetaminophen developmental pharmacokinetics in premature neonates and infants: A pooled population analysis. Anesthesiology 2002;96:1336-45.
26. Palmer GM, Atkins M, Anderson BJ, Smith KR, Culnane TJ, McNally CM, et al. I.V. acetaminophen pharmacokinetics in neonates after multiple doses. Br J Anaesth 2008;101: 523-30.
27. Dart RC, Rumack BH. Intravenous acetaminophen in the United States: Iatrogenic dosing errors. Pediatrics 2012;129:349-53.
28. Ohlsson A, Walia R, Shah SS. Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Rev 2013;4: CD003481.
29. Kauffman RE, Nelson MV. Effect of age on ibuprofen pharmacokinetics and antipyretic response. J Pediatr 1992;121:969-73.
30. Gal P, Ransom JL, Weaver RL, Schall S, Wyble LE, Carlos RQ, et al. Indomethacin pharmacokinetics in neonates: The value of volume of distribution as a marker of permanent patent ductus arteriosus closure. Ther Drug Monit 1991;13:42-5.
31. Wiest DB, Pinson JB, Gal PS, Brundage RC, Schall S, Ransom JL, et al. Population pharmacokinetics of intravenous indomethacin in neonates with symptomatic patent ductus arteriosus. Clin Pharmacol Ther 1991;49:550-7.
32. Mosca F, Bray M, Lattanzio M, Fumagalli M, Tosetto C. Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus. J Pediatr 1997;131:549-54.
33. Burd RS, Tobias JD. The use of ketorolac for postoperative pain management in infants undergoing abdominal surgical procedures. South Med J 2002;95:331-3.
34. Gupta A, Daggett C, Drant S, Rivero N, Lewis A. Prospective randomized trial of ketorolac after congenital heart surgery. J Cardiothorac Vasc Anesth 2004;18:454-7.
35. Moffett BS, Wann TI, Carberry KE, Mott AR. Safety of ketorolac in neonates and infants after cardiac surgery. Paediatr Anaesth 2006;16:424-8.
36. Aldrink JH, Ma M, Wang W, Caniano DA, Wispe J, Puthoff T. Safety of ketorolac in surgical neonates and infants 0-3 months old. J Pediatr Surg 2011;46:1081-5.
37. Bhat R, Chari G, Gulati A, Aldana O, Velamati R, Bhargava H. Pharmacokinetics of a single dose of morphine in preterm infants during the first week of life. J Pediatr 1990;117: 477-81.
38. Scott CS, Riggs KW, Ling EW, Fitzgerald CE, Hill ML, Grunau RV, et al. Morphine pharmacokinetics and pain assessment in premature newborns. J Pediatr 1999;135:423-9.
39. Lynn AM, Slattery JT. Morphine pharmacokinetics in early infancy. Anesthesiology 1987;66:136-9.
40. Lynn AM, Nespeca MK, Opheim KE, Slattery JT. Respiratory effects of intravenous morphine infusions in neonates, infants, and children after cardiac surgery. Anesth Analg 1993;77:695-701.
41. Quinn MW, Wild J, Dean HG, Hartley R, Rushforth JA, Puntis JW, et al. Randomised double-blind controlled trial of effect of morphine on catecholamine concentrations in ventilated pre-Term babies. Lancet 1993;342:324-7.
42. Davis PJ, Killian A, Stiller RL, Cook DR, Guthrie RD, Scierka AM. Pharmacokinetics of alfentanil in newborn premature infants and older children. Dev Pharmacol Ther 1989;13:21-7.
43. Gauntlett IS, Fisher DM, Hertzka RE, Kuhls E, Spellman MJ, Rudolph C. Pharmacokinetics of fentanyl in neonatal humans and lambs: Effects of age. Anesthesiology 1988;69:683-7.
44. Koehntop DE, Rodman JH, Brundage DM, Hegland MG, Buckley JJ. Pharmacokinetics of fentanyl in neonates. Anesth Analg 1986;65:227-32.
45. Yaster M. The dose response of fentanyl in neonatal anesthesia. Anesthesiology 1987;66:433-5.
46. Davis PJ, Galinkin J, McGowan FX, Lynn AM, Yaster M, Rabb MF, et al. A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. I. Emergence and recovery profiles. Anesth Analg 2001;93:1380-6.
47. Galinkin JL, Davis PJ, McGowan FX, Lynn AM, Rabb MF, Yaster M, et al. A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. II. Perioperative breathing patterns in neonates and infants with pyloric stenosis. Anesth Analg 2001;93:1387-92.
48. Ross AK, Davis PJ, Dear Gd GL, Ginsberg B, McGowan FX, Stiller RD, et al. Pharmacokinetics of remifentanil in anesthetized pediatric patients undergoing elective surgery or diagnostic procedures. Anesth Analg 2001;93:1393-401.
49. Dewhirst E, Naguib A, Tobias JD. Chest wall rigidity in two infants after low-dose fentanyl administration. Pediatr Emerg Care 2012;28:465-8.
50. Pokela ML, Ryhanen PT, Koivisto ME, Olkkola KT, Saukkonen AL. Alfentanil-induced rigidity in newborn infants. Anesth Analg 1992;75:252-7.
51. Glick C, Evans OB, Parks BR. Muscle rigidity due to fentanyl infusion in the pediatric patient. South Med J 1996;89: 1119-20.
52. Irazuzta J, Pascucci R, Perlman N, Wessel D. Effects of fentanyl administration on respiratory system compliance in infants. Crit Care Med 1993;21:1001-4.
53. Tobias JD. Remifentanil: Applications in the pediatric ICU population. Am J Pain Manag 1998;8:114-7.
54. Katz R, Kelly HW. Pharmacokinetics of continuous infusions of fentanyl in critically ill children. Crit Care Med 1993;21: 995-1000.
55. Tobias JD, O'Connor TA. Subcutaneous administration of fentanyl for sedation during mechanical ventilation in an infant. Am J Pain Manag 1996;6:115-7.
56. Tobias JD. Spinal anesthesia in infants and children. Paediatr Anaesth 2000;10:5-16.
57. Cote CJ, Zaslavsky A, Downes JJ, Kurth CD, Welborn LG, Warner LO, et al. Postoperative apnea in former preterm infants after inguinal herniorrhaphy. A combined analysis. Anesthesiology 1995;82:809-22.
58. Blaylock M, Engelhardt T, Bissonnette B. Fundamentals of neuronal apoptosis relevant to pediatric anesthesia. Paediatr Anaesth 2010;20:383-95.
59. Bhalla T, Sawardekar A, Dewhirst E, Jagannathan N, Tobias JD. Ultrasound-guided trunk and core blocks in infants and children. J Anesth 2013;27:109-23.
60. Giaufre E, Dalens B, Gombert A. Epidemiology and morbidity of regional anesthesia in children: A one-year prospective survey of the French-Language Society of Pediatric Anesthesiologists. Anesth Analg 1996;83:904-12.
61. Tobias JD. Brachial plexus anesthesia in children. Paediatr Anaesth 2001;11:265-75.
62. Tobias JD. Regional anesthesia of the lower extremity in infants and children. Paediatr Anaesth 2003;13:152-63.
63. Tobias JD, Rasmussen GE, Holcomb GW 3rd, Brock JW 3rd, Morgan WM 3rd. Continuous caudal anesthesia with chloroprocaine as an adjunct to general anesthesia in neonates. Can J Anaesth 1996;43:69-72.
64. Nichols DG, Yaster M, Lynn AM, Helfaer MA, Deshpande JK, Manson PN, et al. Disposition and respiratory effects of intrathecal morphine in children. Anesthesiology 1993;79:733-8.
65. Tobias JD, Deshpande JK, Wetzel RC, Facker J, Maxwell LG, Solca M. Postoperative analgesia. Use of intrathecal morphine in children. Clin Pediatr (Phila) 1990;29:44-8.
66. Bosenberg AT, Bland BA, Schulte-Steinberg O, Downing JW. Thoracic epidural anesthesia via caudal route in infants. Anesthesiology 1988;69:265-9.
67. Rasch DK, Webster DE, Pollard TG, Gurkowski MA. Lumbar and thoracic epidural analgesia via the caudal approach for postoperative pain relief in infants and children. Can J Anaesth 1990;37:359-62.
68. Tsui BC, Seal R, Koller J, Entwistle L, Haugen R, Kearney R. Thoracic epidural analgesia via the caudal approach in pediatric patients undergoing fundoplication using nerve stimulation guidance. Anesth Analg 2001;93:1152-5
69. Bricker SR, Telford RJ, Booker PD. Pharmacokinetics of bupivacaine following intraoperative intercostal nerve block in neonates and in infants aged less than 6 months. Anesthesiology 1989;70:942-7.
70. Mazoit JX, Denson DD, Samii K. Pharmacokinetics of bupivacaine following caudal anesthesia in infants. Anesthesiology 1988;68:387-91.
71. Tobias JD. Caudal epidural block: A review of test dosing and recognition of systemic injection in children. Anesth Analg 2001;93:1156-61.
72. Patil K. Use of intralipid for local anesthetic toxicity in neonates. Paediatr Anaesth 2011;21:1268-9.
73. Larsson BA, Lonnqvist PA, Olsson GL. Plasma concentrations of bupivacaine in neonates after continuous epidural infusion. Anesth Analg 1997;84:501-5.
74. Bosenberg AT, Thomas J, Cronje L, Lopez T, Crean PM, Gustafsson U, Huledal G, Larsson LE. Pharmacokinetics and efficacy of ropivacaine for continuous epidural infusion in neonates and infants. Paediatr Anaesth 2005;15: 739-49.