Variable number tandem repeats in dopamine receptor D4 in Tourette's syndrome

Movement Disorders

Volumn 29, Issue 13, 2014, Pages 1687-1691

  Liu, Shiguo ^a   Cui, Jiajia ^a   Zhang, Xinhua ^a   Wu, Weifeng ^a   Niu, Haitao ^a   Ma, Xu ^b,c   Xu, Hongmei ^a   Yi, Mingji ^a  

^a QINGDAO UNIVERSITY   (China)

^b NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^c WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Meta analysis; TS dopamine receptor D4; VNTR

Indexed keywords

DOPAMINE 4 RECEPTOR;

ADOLESCENT; CASE CONTROL STUDY; CHILD; FAMILY HEALTH; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; GILLES DE LA TOURETTE SYNDROME; HUMAN; MALE; META ANALYSIS (TOPIC); PRESCHOOL CHILD; VARIABLE NUMBER OF TANDEM REPEAT; YOUNG ADULT;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FAMILY HEALTH; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; META-ANALYSIS AS TOPIC; MINISATELLITE REPEATS; RECEPTORS, DOPAMINE D4; TOURETTE SYNDROME; YOUNG ADULT;

EID: 84911212366     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.26027     Document Type: Article

References (17)

1. Missale C, Nash SR, Robinson SW, Jaber M, Caron MG. Dopamine receptors: from structure to function. Physiol Rev 1998;78:189-225.
2. Pawel K, Hauser J, Skibinska M, et al. [Family based association study of DRD1, DRD2, DRD3, DRD4, DAT, COMT gene polymorphism in schizophrenia]. Psychiatr Pol 2010;44:405-413.
3. Millet B, Chabane N, Delorme R, et al. Association between the dopamine receptor D4 (DRD4) gene and obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet 2003;116B:55-59.
4. Huang Y, Liu X, Li T, et al. [Transmission disequilibrium test of DRD4 exon III 48bp variant number tandem repeat polymorphism and tic disorder]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2002;19:100-103.
5. Wang E, Ding YC, Flodman P, et al. The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. Am J Hum Genet 2004;74:931-944.
6. Pauls DL. An update on the genetics of Gilles de la Tourette syndrome. J Psychosom Res 2003;55:7-12.
7. Kano Y, Ohta M, Nagai Y, Pauls DL, Leckman JF. A family study of Tourette syndrome in Japan. Am J Med Genet 2001;105:414-421.
8. Crane J, Fagerness J, Osiecki L, et al. Family-based genetic association study of DLGAP3 in Tourette Syndrome. Am J Med Genet B Neuropsychiatr Genet 2011;156B:108-114.
9. Grice DE, Leckman JF, Pauls DL, et al. Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test. Am J Hum Genet 1996;59:644-652.
10. Diaz-Anzaldua A, Joober R, Riviere JB, et al. Tourette syndrome and dopaminergic genes: a family-based association study in the French Canadian founder population. Mol Psychiatry 2004;9:272-277.
11. Cruz C, Camarena B, King N, et al. Increased prevalence of the seven-repeat variant of the dopamine D4 receptor gene in patients with obsessive-compulsive disorder with tics. Neurosci Lett 1997;231:1-4.
12. Hebebrand J, Nothen MM, Ziegler A, et al. Nonreplication of linkage disequilibrium between the dopamine D4 receptor locus and Tourette syndrome. Am J Hum Genet 1997;61:238-239.
13. Mitsuyasu H, Hirata N, Sakai Y, et al. Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene (DRD4) with schizophrenia and personality traits. J Hum Genet 2001;46:26-31.
14. Schoots O, Van Tol HH. The human dopamine D4 receptor repeat sequences modulate expression. Pharmacogenomics J 2003;3:343-348.
15. Chang FM, Kidd JR, Livak KJ, Pakstis AJ, Kidd KK. The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus. Hum Genet 1996;98:91-101.
16. Wu H, Wu Z, Wang N, Murong s, Fang L, Gan S. Study of dopamine D4 gene polymorphism in Tourette syndrome in Fujian province. Chin J Nerv Ment Dis 2010;36:468-471.
17. Comings DE, Gonzalez N, Wu S, et al. Studies of the 48 bp repeat polymorphism of the DRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse. Am J Med Genet 1999;88:358-368.