-
1
-
-
84892649479
-
Standards of medical care in diabetes–2014
-
(Suppl. 1)
-
American Diabetes Association (2014) Standards of medical care in diabetes–2014. Diabetes Care 37(Suppl. 1): S14–S80.
-
(2014)
Diabetes Care
, vol.37
, pp. S14-S80
-
-
-
2
-
-
84993714443
-
FORXIGA™ (dapagliflozin) now approved in European Union for treatment of type 2 diabetes
-
Available at:, accessed 8 July 2014
-
AstraZeneca (2012) FORXIGA™ (dapagliflozin) now approved in European Union for treatment of type 2 diabetes. Available at: http://www.astrazeneca.com/Media/Press-releases/Article/20121114–forxiga-eu-approval-type-2-diabetes (accessed 8 July 2014).
-
(2012)
-
-
-
3
-
-
84993734051
-
Xigduo™ (dapagliflozin and metformin hydrochloride) approved in the European Union for type 2 diabetes
-
Available at:, accessed 8 July 2014
-
AstraZeneca (2014a) Xigduo™ (dapagliflozin and metformin hydrochloride) approved in the European Union for type 2 diabetes. Available at: http://www.astrazeneca.com/Media/Press-releases/Article/20142101–xigduo-dapagliflozin-and-metformin-hydrochloride (accessed 8 July 2014).
-
(2014)
-
-
-
4
-
-
84993761577
-
U.S. FDA approves FarxigaTM (dapagliflozin) tablets for the treatment of adult patients with type 2 diabetes
-
Available at:, accessed 8 July 2014
-
AstraZeneca (2014b) U.S. FDA approves FarxigaTM (dapagliflozin) tablets for the treatment of adult patients with type 2 diabetes. Available at: http://www.astrazeneca-us.com/media/press-releases/Article/20140113-us-fda-approves-farxiga-tablets (accessed 8 July 2014).
-
(2014)
-
-
-
5
-
-
77953857048
-
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial
-
Bailey C. Gross J. Pieters A. Bastien A. List J. (2010) Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet 375: 2223–2233.
-
(2010)
Lancet
, vol.375
, pp. 2223-2233
-
-
Bailey, C.1
Gross, J.2
Pieters, A.3
Bastien, A.4
List, J.5
-
6
-
-
84861095547
-
Sustained efficacy of dapagliflozin when added to metformin in type 2 diabetes inadequately controlled by metformin monotherapy
-
(Suppl. 1)
-
Bailey C. Gross J. Yadav M. Iqbal N. Mansfield T. List J. (2011) Sustained efficacy of dapagliflozin when added to metformin in type 2 diabetes inadequately controlled by metformin monotherapy. Diabetalogia 54(Suppl. 1): A146.
-
(2011)
Diabetalogia
, vol.54
, pp. A146
-
-
Bailey, C.1
Gross, J.2
Yadav, M.3
Iqbal, N.4
Mansfield, T.5
List, J.6
-
7
-
-
84866003015
-
Dapagliflozin monotherapy in drug-naïve patients with diabetes: a randomized-controlled trial of low-dose range
-
Bailey C. Iqbal N. T–joen C. List J. (2012) Dapagliflozin monotherapy in drug-naïve patients with diabetes: a randomized-controlled trial of low-dose range. Diabetes Obes Metab 14: 951–959.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 951-959
-
-
Bailey, C.1
Iqbal, N.2
T–joen, C.3
List, J.4
-
8
-
-
84921762258
-
Farxiga [package insert]
-
Princeton, NJ: Bristol-Myers Squibb Company.
-
Bristol-Myers Squibb Company (2014) Farxiga [package insert]. Princeton, NJ: Bristol-Myers Squibb Company.
-
(2014)
-
-
-
9
-
-
79959936188
-
National, regional and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants
-
Danaei G. Finucane M. Lu Y. Singh G. Cowan M. Paciorek C. (2011) National, regional and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 378: 31–40.
-
(2011)
Lancet
, vol.378
, pp. 31-40
-
-
Danaei, G.1
Finucane, M.2
Lu, Y.3
Singh, G.4
Cowan, M.5
Paciorek, C.6
-
10
-
-
84891865819
-
Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes
-
Defronzo R. Hompesch M. Kasichayanula S. (2013) Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes. Diabetes Care 36: 3169–3176.
-
(2013)
Diabetes Care
, vol.36
, pp. 3169-3176
-
-
Defronzo, R.1
Hompesch, M.2
Kasichayanula, S.3
-
11
-
-
84871165283
-
Long-term efficacy and safety of add-on dapagliflozin vs add-on glipizide in patients with type 2 diabetes mellitus inadequately controlled with metformin: 2-year results
-
(Suppl. 1)
-
Del Prato S. Nauck M. Rohwedder K. Thuerkauf A. Langkilde A. Parikh S. (2011) Long-term efficacy and safety of add-on dapagliflozin vs add-on glipizide in patients with type 2 diabetes mellitus inadequately controlled with metformin: 2-year results. Diabetalogia 54(Suppl. 1): A852.
-
(2011)
Diabetalogia
, vol.54
, pp. A852
-
-
Del Prato, S.1
Nauck, M.2
Rohwedder, K.3
Thuerkauf, A.4
Langkilde, A.5
Parikh, S.6
-
12
-
-
77956921439
-
Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise
-
Ferrannini E. Ramos S. Salsali A. Tang W. List J. (2010) Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise. Diabetes Care 33: 2217–2224.
-
(2010)
Diabetes Care
, vol.33
, pp. 2217-2224
-
-
Ferrannini, E.1
Ramos, S.2
Salsali, A.3
Tang, W.4
List, J.5
-
13
-
-
79958731052
-
Pitfalls in outpatient diabetes management and inpatient glycemic control
-
Fowler M. (2011) Pitfalls in outpatient diabetes management and inpatient glycemic control. Clinical Diabetes 29: 79–85.
-
(2011)
Clinical Diabetes
, vol.29
, pp. 79-85
-
-
Fowler, M.1
-
14
-
-
38349070535
-
Urinary tract infections in patients with diabetes mellitus: epidemiology, pathogenesis and treatment
-
(Suppl. 1)
-
Geerlings S. (2008) Urinary tract infections in patients with diabetes mellitus: epidemiology, pathogenesis and treatment. Int J Antimicrob Agents 31(Suppl. 1): S54–S57.
-
(2008)
Int J Antimicrob Agents
, vol.31
, pp. S54-S57
-
-
Geerlings, S.1
-
15
-
-
84860218907
-
Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trial
-
Henry R. Murray A. Marmolejo M. Hennicken D. Ptaszynska A. List J. (2012) Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trial. Int J Clin Pract 66: 446–456.
-
(2012)
Int J Clin Pract
, vol.66
, pp. 446-456
-
-
Henry, R.1
Murray, A.2
Marmolejo, M.3
Hennicken, D.4
Ptaszynska, A.5
List, J.6
-
16
-
-
84864285795
-
Management of hyperglycemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
Inzucchi S. Bergenstal R. Buse J. Diamant M. Ferrannini E. Nauck M. (2012) Management of hyperglycemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 55: 1577–1596.
-
(2012)
Diabetologia
, vol.55
, pp. 1577-1596
-
-
Inzucchi, S.1
Bergenstal, R.2
Buse, J.3
Diamant, M.4
Ferrannini, E.5
Nauck, M.6
-
17
-
-
84896701131
-
Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week multicenter, randomized, double-blind placebo-controlled study
-
Jabbour S. Hardy E. Sugg J. Parikh S., Study 10 Group (2014) Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week multicenter, randomized, double-blind placebo-controlled study. Diabetes Care 37: 740–750.
-
(2014)
Diabetes Care
, vol.37
, pp. 740-750
-
-
Jabbour, S.1
Hardy, E.2
Sugg, J.3
Parikh, S.4
-
20
-
-
84876335563
-
Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: a phase II multicentre, randomized, double-blind, placebo-controlled trial
-
Kaku K. Inoue S. Matsuoka O. Kiyosue A. Azuma H. Hayashi N. (2013) Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: a phase II multicentre, randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab 15: 432–440.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 432-440
-
-
Kaku, K.1
Inoue, S.2
Matsuoka, O.3
Kiyosue, A.4
Azuma, H.5
Hayashi, N.6
-
21
-
-
79951897566
-
Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus
-
Kasichayanula S. Chang M. Hasegawa M. Liu X. Yamahira N. LaCreta F. (2011a) Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus. Diabetes Obes Metab 13: 357–365.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 357-365
-
-
Kasichayanula, S.1
Chang, M.2
Hasegawa, M.3
Liu, X.4
Yamahira, N.5
LaCreta, F.6
-
22
-
-
84882591638
-
The influence of kidney function on dapagliflozin exposure, metabolism and pharmacodynamics in healthy subjects and in patients with type 2 diabetes mellitus
-
Kasichayanula S. Liu X. Pe Benito M. Yao M. Pfister M. LaCreta F. (2013) The influence of kidney function on dapagliflozin exposure, metabolism and pharmacodynamics in healthy subjects and in patients with type 2 diabetes mellitus. Br J Clin Pharmacol 76: 432–444.
-
(2013)
Br J Clin Pharmacol
, vol.76
, pp. 432-444
-
-
Kasichayanula, S.1
Liu, X.2
Pe Benito, M.3
Yao, M.4
Pfister, M.5
LaCreta, F.6
-
23
-
-
78649715079
-
Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects
-
Kasichayanula S. Liu X. Shyu W. (2011b) Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects. Diabetes Obes Metab 13: 47–54.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 47-54
-
-
Kasichayanula, S.1
Liu, X.2
Shyu, W.3
-
24
-
-
84897394040
-
Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control
-
Kohan D. Fioretto P. Tan W. List J. (2014) Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control. Kidney Int 85: 962–971.
-
(2014)
Kidney Int
, vol.85
, pp. 962-971
-
-
Kohan, D.1
Fioretto, P.2
Tan, W.3
List, J.4
-
25
-
-
67349180574
-
Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects
-
Komoroski B. Vachharajani N. Boulton D. Kornhauser D. Geraldes M. Li L. (2009) Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects. Clin Pharmacol Ther 85: 520–526.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 520-526
-
-
Komoroski, B.1
Vachharajani, N.2
Boulton, D.3
Kornhauser, D.4
Geraldes, M.5
Li, L.6
-
26
-
-
65349196064
-
Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
-
List J. Woo V. Morales E. Tang W. Fiedorek F. (2009) Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care 32: 650–657.
-
(2009)
Diabetes Care
, vol.32
, pp. 650-657
-
-
List, J.1
Woo, V.2
Morales, E.3
Tang, W.4
Fiedorek, F.5
-
27
-
-
33845338724
-
Projections of global mortality and burden of disease from 2002 to 2030
-
Mathers C. Loncar D. (2006) Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3: e442.
-
(2006)
PLoS Med
, vol.3
, pp. e442
-
-
Mathers, C.1
Loncar, D.2
-
28
-
-
80155124676
-
Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin
-
Nauck M. Del Prato S. Meier J. Duran-Garcia S. Rohwedder K. Elze M. (2011) Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin. Diabetes Care 34: 2015–2022.
-
(2011)
Diabetes Care
, vol.34
, pp. 2015-2022
-
-
Nauck, M.1
Del Prato, S.2
Meier, J.3
Duran-Garcia, S.4
Rohwedder, K.5
Elze, M.6
-
29
-
-
84862875221
-
Effects of dapagliflozin, an SGLT2 inhibitor, on HbA1c, body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy
-
Rosenstock J. Vico M. Wei L. Salsali A. List J. (2012) Effects of dapagliflozin, an SGLT2 inhibitor, on HbA1c, body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy. Diabetes Care 35: 1473–1478.
-
(2012)
Diabetes Care
, vol.35
, pp. 1473-1478
-
-
Rosenstock, J.1
Vico, M.2
Wei, L.3
Salsali, A.4
List, J.5
-
30
-
-
84882254968
-
The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988–2010
-
Stark Casagrande S. Fradkin J. Saydah S. Rust K. Cowie C. (2013) The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988–2010. Diabetes Care 36: 2271–2279.
-
(2013)
Diabetes Care
, vol.36
, pp. 2271-2279
-
-
Stark Casagrande, S.1
Fradkin, J.2
Saydah, S.3
Rust, K.4
Cowie, C.5
-
31
-
-
80052524011
-
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial
-
Strojek K. Yoon K. Hruba V. Elze M. Langkilde A. Parikh S. (2011) Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial. Diabetes Obes Metab 13: 928–938.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 928-938
-
-
Strojek, K.1
Yoon, K.2
Hruba, V.3
Elze, M.4
Langkilde, A.5
Parikh, S.6
-
32
-
-
0028963260
-
Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years
-
UK Prospective Diabetes Study (1995) Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years. BMJ 310: 83–88.
-
(1995)
BMJ
, vol.310
, pp. 83-88
-
-
-
33
-
-
0028817815
-
Overview of 6 years– therapy of type II diabetes: a progressive disease. UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (1995) Overview of 6 years– therapy of type II diabetes: a progressive disease. UK Prospective Diabetes Study (UKPDS) Group. Diabetes 44: 1249–1258.
-
(1995)
Diabetes
, vol.44
, pp. 1249-1258
-
-
-
34
-
-
0036937335
-
Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2)
-
van den Heuvel L. Assink K. Willemsen M. Monnens L. (2002) Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2). Hum Genet 111: 544–547.
-
(2002)
Hum Genet
, vol.111
, pp. 544-547
-
-
van den Heuvel, L.1
Assink, K.2
Willemsen, M.3
Monnens, L.4
-
35
-
-
84993755982
-
Effects of dapagliflozin on blood pressure in diabetic patients with hypertension inadequately controlled by a renin–angiotensin system blocker
-
Presented at the Annual Meeting of the American Heart Association (AHA);, 16–20 November 2013,;, Dallas, TX. Poster 2095
-
Weber M. Mansfield T. Alessi F. Ptaszynska A. (2013a) Effects of dapagliflozin on blood pressure in diabetic patients with hypertension inadequately controlled by a renin–angiotensin system blocker. Presented at the Annual Meeting of the American Heart Association (AHA); 16–20 November 2013; Dallas, TX. Poster 2095.
-
(2013)
-
-
Weber, M.1
Mansfield, T.2
Alessi, F.3
Ptaszynska, A.4
-
36
-
-
84993699265
-
Dapagliflozin for reduction of blood pressure in diabetic patients inadequately controlled with combination antihypertensive regimen
-
Presented at the Annual Meeting of the American Heart Association (AHA);, 16–20 November 2013,;, Dallas, TX. Poster 2097
-
Weber M. Mansfield T. T–joen C. (2013b) Dapagliflozin for reduction of blood pressure in diabetic patients inadequately controlled with combination antihypertensive regimen. Presented at the Annual Meeting of the American Heart Association (AHA); 16–20 November 2013; Dallas, TX. Poster 2097.
-
(2013)
-
-
Weber, M.1
Mansfield, T.2
T–joen, C.3
-
37
-
-
69549095914
-
A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers
-
Wilding J. Norwood P. T–joen C. Bastien A. List J. Fiedorek F. (2009) A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers. Diabetes Care 32: 1656–1662.
-
(2009)
Diabetes Care
, vol.32
, pp. 1656-1662
-
-
Wilding, J.1
Norwood, P.2
T–joen, C.3
Bastien, A.4
List, J.5
Fiedorek, F.6
-
38
-
-
84892488179
-
Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years
-
Wilding J. Woo V. Rohwedder K. Sugg J. Parikh S. for the Dapagliflozin 006 Study Group (2014) Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years. Diabetes Obes Metab 16: 124–136.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 124-136
-
-
Wilding, J.1
Woo, V.2
Rohwedder, K.3
Sugg, J.4
Parikh, S.5
-
39
-
-
0034997336
-
Renal Na+-glucose cotransporters
-
Wright E. (2001) Renal Na+-glucose cotransporters. Am J Physiol Renal Physiol 280: F10–F18.
-
(2001)
Am J Physiol Renal Physiol
, vol.280
, pp. F10-F18
-
-
Wright, E.1
-
40
-
-
1242272759
-
The sodium/glucose cotransport family SLC5
-
Wright E. Turk E. (2004) The sodium/glucose cotransport family SLC5. Eur J Physiol 447: 510–518.
-
(2004)
Eur J Physiol
, vol.447
, pp. 510-518
-
-
Wright, E.1
Turk, E.2
-
41
-
-
77953181310
-
Dapagliflozin treatment in patients with different stages of type 2 diabetes mellitus: effects on glycaemic control and body weight
-
Zhang L. Feng Y. List J. Kasichayanula S. Pfister M. (2010) Dapagliflozin treatment in patients with different stages of type 2 diabetes mellitus: effects on glycaemic control and body weight. Diabetes Obes Metab 12: 510–516.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 510-516
-
-
Zhang, L.1
Feng, Y.2
List, J.3
Kasichayanula, S.4
Pfister, M.5
|