Actinomyces osteomyelitis in bisphosphonate-related osteonecrosis of the jaw (BRONJ): the missing link?

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 33, Issue 11, 2014, Pages 1873-1880

  De Ceulaer, J ^a   Tacconelli, E ^b   Vandecasteele, S J ^c  

^a AZ Sint Jan Brugge   (Belgium)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c Department of Internal Medicine   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE;

ACTINOMYCES; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM DETECTION; CLINICAL FEATURE; HUMAN; INFLAMMATION; JAW OSTEONECROSIS; NONHUMAN; OSTEOMYELITIS; PREVALENCE; REVIEW; TREATMENT RESPONSE; ACTINOMYCOSIS; BISPHOSPHONATE-ASSOCIATED OSTEONECROSIS OF THE JAW; CHEMICALLY INDUCED; COMPLICATION; ISOLATION AND PURIFICATION; MICROBIOLOGY; PATHOLOGY;

ACTINOMYCES; ACTINOMYCOSIS; BISPHOSPHONATE-ASSOCIATED OSTEONECROSIS OF THE JAW; HUMANS; OSTEOMYELITIS;

EID: 84911005618     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-014-2160-5     Document Type: Review

References (42)

1. Wang J, Goodger NM, Pogrel MA (2003) Osteonecrosis of the jaws associated with cancer chemotherapy. J Oral Maxillofac Surg 61(9):1104–1107
2. Marx RE (2008) Uncovering the cause of “phossy jaw” Circa 1858 to 1906: oral and maxillofacial surgery closed case files—case closed. J Oral Maxillofac Surg 66(11):2356–2363
3. Advisory Task Force on Bisphosphonate-Related Ostenonecrosis of the Jaws, American Association of Oral and Maxillofacial Surgeons (2007) American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg 65(3):369–376
4. Ficarra G, Beninati F (2007) Bisphosphonate-related osteonecrosis of the jaws: an update on clinical, pathological and management aspects. Head Neck Pathol 1(2):132–140
5. Marx RE, Sawatari Y, Fortin M, Broumand V (2005) Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg 63(11):1567–1575
6. Drake MT, Clarke BL, Khosla S (2008) Bisphosphonates: mechanism of action and role in clinical practice. Mayo Clin Proc 83(9):1032–1045
7. Aghaloo TL, Kang B, Sung EC, Shoff M, Ronconi M, Gotcher JE et al (2011) Periodontal disease and bisphosphonates induce osteonecrosis of the jaws in the rat. J Bone Miner Res 26(8):1871–1882
8. Anavi-Lev K, Anavi Y, Chaushu G, Alon DM, Gal G, Kaplan I (2013) Bisphosphonate related osteonecrosis of the jaws: clinico-pathological investigation and histomorphometric analysis. Oral Surg Oral Med Oral Pathol Oral Radiol 115(5):660–666
9. Favus MJ (2010) Bisphosphonates for osteoporosis. N Engl J Med 363(21):2027–2035
10. Hughes JP, Baron R, Buckland DH, Cooke MA, Craig JD, Duffield DP et al (1962) Phosphorus necrosis of the jaw: a present-day study. Br J Ind Med 19:83–99
11. Pulverer G, Schütt-Gerowitt H, Schaal KP (2003) Human cervicofacial actinomycoses: microbiological data for 1997 cases. Clin Infect Dis 37(4):490–497
12. Smego RA Jr, Foglia G (1998) Actinomycosis. Clin Infect Dis 26(6):1255–1261
13. Sedghizadeh PP, Kumar SK, Gorur A, Schaudinn C, Shuler CF, Costerton JW (2008) Identification of microbial biofilms in osteonecrosis of the jaws secondary to bisphosphonate therapy. J Oral Maxillofac Surg 66(4):767–775
14. Sedghizadeh PP, Kumar SK, Gorur A, Schaudinn C, Shuler CF, Costerton JW (2009) Microbial biofilms in osteomyelitis of the jaw and osteonecrosis of the jaw secondary to bisphosphonate therapy. J Am Dent Assoc 140(10):1259–1265
15. Smith AJ, Hall V, Thakker B, Gemmell CG (2005) Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents. J Antimicrob Chemother 56(2):407–409
16. Evans AS (1976) Causation and disease: the Henle–Koch postulates revisited. Yale J Biol Med 49(2):175–195
17. Hansen T, Kunkel M, Springer E, Walter C, Weber A, Siegel E et al (2007) Actinomycosis of the jaws—histopathological study of 45 patients shows significant involvement in bisphosphonate-associated osteonecrosis and infected osteoradionecrosis. Virchows Arch 451(6):1009–1017
18. Mücke T, Koschinski J, Deppe H, Wagenpfeil S, Pautke C, Mitchell DA et al (2011) Outcome of treatment and parameters influencing recurrence in patients with bisphosphonate-related osteonecrosis of the jaws. J Cancer Res Clin Oncol 137(5):907–913
19. Abu-Id MH, Açil Y, Gottschalk J, Kreusch T (2006) Bisphosphonate-associated osteonecrosis of the jaw. Mund Kiefer Gesichtschir 10(2):73–81
20. Hansen T, Kunkel M, Weber A, James Kirkpatrick C (2006) Osteonecrosis of the jaws in patients treated with bisphosphonates—histomorphologic analysis in comparison with infected osteoradionecrosis. J Oral Pathol Med 35(3):155–160
21. Marx RE, Tursun R (2012) Suppurative osteomyelitis, bisphosphonate induced osteonecrosis, osteoradionecrosis: a blinded histopathologic comparison and its implications for the mechanism of each disease. Int J Oral Maxillofac Surg 41(3):283–289
22. Hansen T, Kunkel M, Kirkpatrick CJ, Weber A (2006) Actinomyces in infected osteoradionecrosis—underestimated? Hum Pathol 37(1):61–67
23. Lee CY, Pien FD, Suzuki JB (2011) Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. Implant Dent 20(5):331–336
24. Hokugo A, Christensen R, Chung EM, Sung EC, Felsenfeld AL, Sayre JW et al (2010) Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats. J Bone Miner Res 25(6):1337–1349
25. Biasotto M, Chiandussi S, Zacchigna S, Moimas S, Dore F, Pozzato G et al (2010) A novel animal model to study non-spontaneous bisphosphonates osteonecrosis of jaw. J Oral Pathol Med 39(5):390–396
26. Kos M, Kuebler JF, Luczak K, Engelke W (2010) Bisphosphonate-related osteonecrosis of the jaws: a review of 34 cases and evaluation of risk. J Craniomaxillofac Surg 38(4):255–259
27. O’Ryan FS, Khoury S, Liao W, Han MM, Hui RL, Baer D et al (2009) Intravenous bisphosphonate-related osteonecrosis of the jaw: bone scintigraphy as an early indicator. J Oral Maxillofac Surg 67(7):1363–1372
28. Nefelova MV, Negrin S, Filippova MS, Ermakova GN (1986) Effect of orthophosphate on the formation of the antibiotic nonactin. Nauchnye Doki Vyss Shkoly Biol Nauki (2):87–89
29. Makarevich VG, Upiter GD, Slugina MD, Tarasova SS, Gravit NF (1975) Effect of orthophosphate on the growth rate and biosynthesis of tetracycline by an Actinomyces aureofaciens culture. Antibiotiki 20(4):295–299
30. Schipmann S, Metzler P, Rössle M, Zemann W, von Jackowski J, Obwegeser JA et al (2013) Osteopathology associated with bone resorption inhibitors—which role does Actinomyces play? A presentation of 51 cases with systematic review of the literature. J Oral Pathol Med 42:587–593
31. Pigrau-Serrallach C, Cabral-Galeano E, Almirante-Gragera B, Sordé-Masip R, Rodriguez-Pardo D, Fernandez-Hidalgo N et al. (2014) Long-term follow-up of jaw osteomyelitis associated with bisphosphonate use in a tertiary-care center. Enferm Infecc Microbiol Clin 32:18–22
32. Arranz Caso JA, Flores Ballester E, Ngo Pombe S, López Pizarro V, Dominguez-Mompello JL, Restoy Lozano A (2012) Bisphosphonate related osteonecrosis of the jaw and infection with Actinomyces. Med Clin (Barc) 139(15):676–680
33. Curi MM, Cossolin GS, Koga DH, Zardetto C, Christianini S, Feher O et al (2011) Bisphosphonate-related osteonecrosis of the jaws—an initial case series report of treatment combining partial bone resection and autologous platelet-rich plasma. J Oral Maxillofac Surg 69(9):2465–2472
34. Kos M, Brusco D, Kuebler J, Engelke W (2010) Clinical comparison of patients with osteonecrosis of the jaws, with and without a history of bisphosphonates administration. Int J Oral Maxillofac Surg 39(11):1097–1102
35. Lazarovici TS, Yahalom R, Taicher S, Elad S, Hardan I, Yarom N (2009) Bisphosphonate-related osteonecrosis of the jaws: a single-center study of 101 patients. J Oral Maxillofac Surg 67(4):850–855
36. Naik NH, Russo TA (2009) Bisphosphonate-related osteonecrosis of the jaw: the role of actinomyces. Clin Infect Dis 49(11):1729–1732
37. Saussez S, Javadian R, Hupin C, Magremanne M, Chantrain G, Loeb I et al (2009) Bisphosphonate-related osteonecrosis of the jaw and its associated risk factors: a Belgian case series. Laryngoscope 119(2):323–329
38. Bisdas S, Chambron Pinho N, Smolarz A, Sader R, Vogl TJ, Mack MG (2008) Biphosphonate-induced osteonecrosis of the jaws: CT and MRI spectrum of findings in 32 patients. Clin Radiol 63(1):71–77
39. Lobato JV, Maurício AC, Rodrigues JM, Cavaleiro MV, Cortez PP, Xavier L et al (2008) Jaw avascular osteonecrosis after treatment of multiple myeloma with zoledronate. J Plast Reconstr Aesthet Surg 61(1):99–106
40. Magremanne M, Vervaet C, Dufrasne L, Declercq I, Legrand W, Daelemans P (2006) Bisphosphonates and maxillo-mandibular osteo(chemo)necrosis. Rev Stomatol Chir Maxillofac 107(6):423–428
41. Biasotto M, Chiandussi S, Dore F, Rinaldi A, Rizzardi C, Cavalli F et al (2006) Clinical aspects and management of bisphosphonates-associated osteonecrosis of the jaws. Acta Odontol Scand 64(6):348–354
42. Lugassy G, Shaham R, Nemets A, Ben-Dor D, Nahlieli O (2004) Severe osteomyelitis of the jaw in long-term survivors of multiple myeloma: a new clinical entity. Am J Med 117(6):440–441