The protective effects of Donepezil (DP) against cartilage matrix destruction induced by TNF-α

Biochemical and Biophysical Research Communications

Volumn 454, Issue 1, 2014, Pages 115-118

  Zhang, Dawei ^a   Zhou, Yue ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Collagen type II; Donepezil; MMP 13; Osteoarthritis; TNF

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE 3; DONEPEZIL; INTERFERON REGULATORY FACTOR 1; MESSENGER RNA; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CHOLINESTERASE INHIBITOR; INDAN DERIVATIVE; MMP13 PROTEIN, HUMAN; PIPERIDINE DERIVATIVE; STAT1 PROTEIN, HUMAN;

ARTICLE; CARTILAGE CELL; CARTILAGE INJURY; CARTILAGE MATRIX; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; HUMAN TISSUE; OSTEOARTHRITIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; THERAPY EFFECT; ANTAGONISTS AND INHIBITORS; ARTICULAR CARTILAGE; BIOSYNTHESIS; DRUG EFFECTS; ENZYME INDUCTION; GENETICS; METABOLISM;

CARTILAGE, ARTICULAR; CHOLINESTERASE INHIBITORS; CHONDROCYTES; COLLAGEN TYPE II; ENZYME INDUCTION; HUMANS; INDANS; INTERFERON REGULATORY FACTOR-1; MATRIX METALLOPROTEINASE 13; OSTEOARTHRITIS; PIPERIDINES; PROTEOLYSIS; RNA, MESSENGER; STAT1 TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84910108906     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.046     Document Type: Article

References (18)

1. P. Richette, C. Roux, Impact of treatments for osteoporosis on cartilage biomarkers in humans, Osteoporos. Int. 23 (Suppl. 8) (2012) S877-S880.
2. P.G. Mitchell, H.A. Magna, L.M. Reeves, L.L. Lopresti-Morrow, S.A. Yocum, P.J. Rosner, et al., Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage, J. Clin. Invest. 97 (1996) 761-768.
3. T. Taniguchi, K. Ogasawara, A. Takaoka, et al., IRF family of transcription factors as regulators of host defense, Annu. Rev. Immunol. 19 (2001) 623-655.
4. Y.A. Asiri, G.A.E. Mostafa, Donepezil, Profiles Drug Subst. Excip. Relat. Methodol. 35 (2010) 117-150.
5. K.B. Liew, Y.T.F. Tan, K.K. Peh, Characterization of oral disintegrating film containing Donepezil for Alzheimer disease, AAPS PharmSciTech. 13 (2012) 134-142.
6. J. Hwang, H. Hwang, H.W. Lee, et al., Microglia signaling as a target of Donepezil, Neuropharmacology 58 (2010) 1122-1129.
7. Y. Yoshiyama, A. Kojima, C. Ishikawa, K. Arai, Anti-inflammatory action of Donepezil ameliorates tau pathology, synaptic loss, and neurodegeneration in a tauopathy mouse model, J. Alzheimers Dis. 22 (2010) 295-306.
8. M. Reale, C. Iarlori, F. Gambi, et al., The acetylcholinesterase inhibitor, Donepezil, regulates a Th2 bias in Alzheimer's disease patients, Neuropharmacology 50 (2006) 606-613.
9. B. Sheng, B. Song, Z. Zheng, F. Zhou, G. Lu, N. Zhao, X. Zhang, Y. Gong, Abnormal cleavage of APP impairs its functions in cell adhesion and migration, Neurosci. Lett. 450 (2009) 327-331.
10. F.M. Griffin, K. Math, G.R. Scuderi, et al., Anatomy of the epicondyles of the distal femur: MRI analysis of normal knees, J. Arthroplasty 15 (2000) 354-359.
11. M.P. Vincenti, C.E. Brinckerhoff, Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors, Arthritis Res. 4 (2002) 157-164.
12. T. Shiomi, V. Lemaître, J. D'Armiento, et al., Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases, Pathol. Int. 60 (2010) 477-496.
13. H. Lu, C. Zeng, H. Zhao, et al., Glatiramer acetate inhibits degradation of collagen II by suppressing the activity of interferon regulatory factor-1, Biochem. Biophys. Res. Commun. 448 (2014) 323-328.
14. H. Lim, H.P. Kim, Matrix metalloproteinase-13 expression in IL-1b-treated chondrocytes by activation of the p38 MAPK/c-Fos/AP-1 and JAK/STAT pathways, Arch. Pharmacal Res. 34 (2011) 109-117.
15. J. Hwang, H. Hwang, H.W. Lee, K. Suk, Microglia signaling as a target of Donepezil, Neuropharmacology 58 (2010) 1122-1129.
16. M. Arikawa, Y. Kakinuma, T. Handa, et al., Donepezil, anti-Alzheimer's disease drug, prevents cardiac rupture during acute phase of myocardial infarction in mice, PLoS ONE 6 (2011) e20629.
17. Y. Jiang, Y. Zou, S. Chen, et al., The anti-inflammatory effect of Donepezil on experimental autoimmune encephalomyelitis in C57 BL/6 mice, Neuropharmacology 73 (2013) 415-424.
18. M. Sochocka, E. Zaczyńska, A. Taboł, et al., The influence of Donepezil and EGb 761 on the innate immunity of human leukocytes: effect on the NF-κB system, Int. Immunopharmacol. 10 (2010) 1505-1513.