-
1
-
-
33745591621
-
Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: Allopregnanolone as a proof of concept neurogenic agent
-
R.D. Brinton, and J.M. Wang Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: allopregnanolone as a proof of concept neurogenic agent Curr Alzheimer Res 3 2006 185 190
-
(2006)
Curr Alzheimer Res
, vol.3
, pp. 185-190
-
-
Brinton, R.D.1
Wang, J.M.2
-
2
-
-
0242300273
-
Transient expression of doublecortin during adult neurogenesis
-
J.P. Brown, S. Couillard-Després, C.M. Cooper-Kuhn, J. Winkler, L. Aigner, and H.G. Kuhn Transient expression of doublecortin during adult neurogenesis J Comp Neurol 467 2003 1 10
-
(2003)
J Comp Neurol
, vol.467
, pp. 1-10
-
-
Brown, J.P.1
Couillard-Després, S.2
Cooper-Kuhn, C.M.3
Winkler, J.4
Aigner, L.5
Kuhn, H.G.6
-
3
-
-
38149116895
-
Adult neurogenesis is functionally associated with AD-like neurodegeneration
-
Q. Chen, A. Nakajima, S.H. Choi, X. Xiong, S.S. Sisodia, and Y.-P. Tang Adult neurogenesis is functionally associated with AD-like neurodegeneration Neurobiol Dis 29 2008 316 326
-
(2008)
Neurobiol Dis
, vol.29
, pp. 316-326
-
-
Chen, Q.1
Nakajima, A.2
Choi, S.H.3
Xiong, X.4
Sisodia, S.S.5
Tang, Y.-P.6
-
4
-
-
0042808465
-
Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain
-
M.A. Curtis, E.B. Penney, A.G. Pearson, W.M. van Roon-Mom, N.J. Butterworth, and M. Dragunow Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain Proc Natl Acad Sci U S A 100 2003 9023 9027
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9023-9027
-
-
Curtis, M.A.1
Penney, E.B.2
Pearson, A.G.3
Van Roon-Mom, W.M.4
Butterworth, N.J.5
Dragunow, M.6
-
5
-
-
43749120042
-
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus
-
T.H. Davis, T.L. Cuellar, S.M. Koch, A.J. Barker, B.D. Harfe, and M.T. McManus Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus J Neurosci 28 2008 4322 4330
-
(2008)
J Neurosci
, vol.28
, pp. 4322-4330
-
-
Davis, T.H.1
Cuellar, T.L.2
Koch, S.M.3
Barker, A.J.4
Harfe, B.D.5
McManus, M.T.6
-
6
-
-
0027354484
-
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
-
D.W. Dickson, S.C. Lee, L.A. Mattiace, S.H. Yen, and C. Brosnan Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease Glia 7 1993 75 83
-
(1993)
Glia
, vol.7
, pp. 75-83
-
-
Dickson, D.W.1
Lee, S.C.2
Mattiace, L.A.3
Yen, S.H.4
Brosnan, C.5
-
7
-
-
32544460592
-
Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease
-
M.H. Donovan, U. Yazdani, R.D. Norris, D. Games, D.C. German, and A.J. Eisch Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease J Comp Neurol 495 2006 70 83
-
(2006)
J Comp Neurol
, vol.495
, pp. 70-83
-
-
Donovan, M.H.1
Yazdani, U.2
Norris, R.D.3
Games, D.4
German, D.C.5
Eisch, A.J.6
-
8
-
-
0344742225
-
Inflammation is detrimental for neurogenesis in adult brain
-
C.T. Ekdahl, J.-H. Claasen, S. Bonde, Z. Kokaia, and O. Lindvall Inflammation is detrimental for neurogenesis in adult brain Proc Natl Acad Sci U S A 100 2003 13632 13637
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13632-13637
-
-
Ekdahl, C.T.1
Claasen, J.-H.2
Bonde, S.3
Kokaia, Z.4
Lindvall, O.5
-
9
-
-
0344519489
-
Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice
-
M. Fukaya, A. Kato, C. Lovett, S. Tonegawa, and M. Watanabe Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice Proc Natl Acad Sci U S A 100 2003 4855 4860
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4855-4860
-
-
Fukaya, M.1
Kato, A.2
Lovett, C.3
Tonegawa, S.4
Watanabe, M.5
-
10
-
-
79951822996
-
Presenilin-1 regulates neural progenitor cell differentiation in the adult brain
-
A. Gadadhar, R. Marr, and O. Lazarov Presenilin-1 regulates neural progenitor cell differentiation in the adult brain J Neurosci 31 2011 2615 2623
-
(2011)
J Neurosci
, vol.31
, pp. 2615-2623
-
-
Gadadhar, A.1
Marr, R.2
Lazarov, O.3
-
11
-
-
0034712047
-
Mammalian neural stem cells
-
F.H. Gage Mammalian neural stem cells Science 287 2000 1433 1438
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
12
-
-
0036469896
-
Neurogenesis in the adult brain
-
F.H. Gage Neurogenesis in the adult brain J Neurosci 22 2002 612 613
-
(2002)
J Neurosci
, vol.22
, pp. 612-613
-
-
Gage, F.H.1
-
13
-
-
47749126515
-
Why neurodegenerative diseases are progressive: Uncontrolled inflammation drives disease progression
-
H.M. Gao, and J.S. Hong Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression Trends Immunol 29 2008 357 365
-
(2008)
Trends Immunol
, vol.29
, pp. 357-365
-
-
Gao, H.M.1
Hong, J.S.2
-
14
-
-
0028926976
-
Interleukin-1 expression in different plaque types in Alzheimer's disease: Significance in plaque evolution
-
W.S. Griffin, J.G. Sheng, G.W. Roberts, and R.E. Mrak Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution J Neuropathol Exp Neurol 54 1995 276 281
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 276-281
-
-
Griffin, W.S.1
Sheng, J.G.2
Roberts, G.W.3
Mrak, R.E.4
-
15
-
-
23344439006
-
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb
-
B.D. Harfe, M.T. McManus, J.H. Mansfield, E. Hornstein, and C.J. Tabin The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb Proc Natl Acad Sci U S A 102 2005 10898 10903
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 10898-10903
-
-
Harfe, B.D.1
McManus, M.T.2
Mansfield, J.H.3
Hornstein, E.4
Tabin, C.J.5
-
16
-
-
0042362874
-
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
-
N.J. Haughey, A. Nath, S.L. Chan, A.C. Borchard, M.S. Rao, and M.P. Mattson Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease J Neurochem 83 2002 1509 1524
-
(2002)
J Neurochem
, vol.83
, pp. 1509-1524
-
-
Haughey, N.J.1
Nath, A.2
Chan, S.L.3
Borchard, A.C.4
Rao, M.S.5
Mattson, M.P.6
-
17
-
-
63349094897
-
Alterations of the microRNA network cause neurodegenerative disease
-
S.S. Hébert, and B. De Strooper Alterations of the microRNA network cause neurodegenerative disease Trends Neurosci 32 2009 199 206
-
(2009)
Trends Neurosci
, vol.32
, pp. 199-206
-
-
Hébert, S.S.1
De Strooper, B.2
-
18
-
-
44049108170
-
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression
-
S.S. Hébert, K. Horré, L. Nicolaï, A.S. Papadopoulou, W. Mandemakers, and A.N. Silahtaroglu Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression Proc Natl Acad Sci U S A 105 2008 6415 6420
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 6415-6420
-
-
Hébert, S.S.1
Horré, K.2
Nicolaï, L.3
Papadopoulou, A.S.4
Mandemakers, W.5
Silahtaroglu, A.N.6
-
19
-
-
77957735016
-
Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration
-
S.S. Hébert, A.S. Papadopoulou, P. Smith, M.-C. Galas, E. Planel, and A.N. Silahtaroglu Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration Hum Mol Genet 19 2010 3959 3969
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3959-3969
-
-
Hébert, S.S.1
Papadopoulou, A.S.2
Smith, P.3
Galas, M.-C.4
Planel, E.5
Silahtaroglu, A.N.6
-
20
-
-
0029051259
-
Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients
-
M. Huell, S. Strauss, B. Volk, M. Berger, and J. Bauer Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients Acta Neuropathol 89 1995 544 551
-
(1995)
Acta Neuropathol
, vol.89
, pp. 544-551
-
-
Huell, M.1
Strauss, S.2
Volk, B.3
Berger, M.4
Bauer, J.5
-
21
-
-
0346458659
-
Increased hippocampal neurogenesis in Alzheimer's disease
-
K. Jin, A.L. Peel, X.O. Mao, L. Xie, B.A. Cottrell, and D.C. Henshall Increased hippocampal neurogenesis in Alzheimer's disease Proc Natl Acad Sci U S A 101 2004 343 347
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 343-347
-
-
Jin, K.1
Peel, A.L.2
Mao, X.O.3
Xie, L.4
Cottrell, B.A.5
Henshall, D.C.6
-
22
-
-
76649086338
-
RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells
-
Y. Kawase-Koga, R. Low, G. Otaegi, A. Pollock, H. Deng, and F. Eisenhaber RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells J Cell Sci 123 2010 586 594
-
(2010)
J Cell Sci
, vol.123
, pp. 586-594
-
-
Kawase-Koga, Y.1
Low, R.2
Otaegi, G.3
Pollock, A.4
Deng, H.5
Eisenhaber, F.6
-
23
-
-
70350708160
-
Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system
-
Y. Kawase-Koga, G. Otaegi, and T. Sun Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system Dev Dyn 238 2009 2800 2812
-
(2009)
Dev Dyn
, vol.238
, pp. 2800-2812
-
-
Kawase-Koga, Y.1
Otaegi, G.2
Sun, T.3
-
24
-
-
0037262305
-
Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice
-
G. Kempermann, D. Gast, G. Kronenberg, M. Yamaguchi, and F.H. Gage Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice Development 130 2003 391 399
-
(2003)
Development
, vol.130
, pp. 391-399
-
-
Kempermann, G.1
Gast, D.2
Kronenberg, G.3
Yamaguchi, M.4
Gage, F.H.5
-
25
-
-
34548537573
-
A microRNA feedback circuit in midbrain dopamine neurons
-
J. Kim, K. Inoue, J. Ishii, W.B. Vanti, S.V. Voronov, and E. Murchison A microRNA feedback circuit in midbrain dopamine neurons Science 317 2007 1220 1224
-
(2007)
Science
, vol.317
, pp. 1220-1224
-
-
Kim, J.1
Inoue, K.2
Ishii, J.3
Vanti, W.B.4
Voronov, S.V.5
Murchison, E.6
-
26
-
-
77952543738
-
Neurogenesis and Alzheimer's disease: At the crossroads
-
O. Lazarov, and R.A. Marr Neurogenesis and Alzheimer's disease: at the crossroads Exp Neurol 223 2010 267 281
-
(2010)
Exp Neurol
, vol.223
, pp. 267-281
-
-
Lazarov, O.1
Marr, R.A.2
-
27
-
-
4444381084
-
Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory
-
B. Leuner, S. Mendolia-Loffredo, Y. Kozorovitskiy, D. Samburg, E. Gould, and T.J. Shors Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory J Neurosci 24 2004 7477 7481
-
(2004)
J Neurosci
, vol.24
, pp. 7477-7481
-
-
Leuner, B.1
Mendolia-Loffredo, S.2
Kozorovitskiy, Y.3
Samburg, D.4
Gould, E.5
Shors, T.J.6
-
28
-
-
0029917887
-
Anti-inflammatory drugs in the fight against Alzheimer's disease
-
P.L. McGeer, and E.G. McGeer Anti-inflammatory drugs in the fight against Alzheimer's disease Ann N Y Acad Sci 777 1996 213 220
-
(1996)
Ann N y Acad Sci
, vol.777
, pp. 213-220
-
-
McGeer, P.L.1
McGeer, E.G.2
-
29
-
-
0345189366
-
Inflammatory blockade restores adult hippocampal neurogenesis
-
M.L. Monje, H. Toda, and T.D. Palmer Inflammatory blockade restores adult hippocampal neurogenesis Science 302 2003 1760 1765
-
(2003)
Science
, vol.302
, pp. 1760-1765
-
-
Monje, M.L.1
Toda, H.2
Palmer, T.D.3
-
30
-
-
84888413862
-
Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival
-
X. Pang, E.M. Hogan, A. Casserly, G. Gao, P.D. Gardner, and A.R. Tapper Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival Mol Cell Neurosci 58 2014 22 28
-
(2014)
Mol Cell Neurosci
, vol.58
, pp. 22-28
-
-
Pang, X.1
Hogan, E.M.2
Casserly, A.3
Gao, G.4
Gardner, P.D.5
Tapper, A.R.6
-
31
-
-
0034006822
-
Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice
-
C. Rampon, Y.P. Tang, J. Goodhouse, E. Shimizu, M. Kyin, and J.Z. Tsien Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice Nat Neurosci 3 2000 238 244
-
(2000)
Nat Neurosci
, vol.3
, pp. 238-244
-
-
Rampon, C.1
Tang, Y.P.2
Goodhouse, J.3
Shimizu, E.4
Kyin, M.5
Tsien, J.Z.6
-
32
-
-
51849123324
-
Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease
-
J.J. Rodriguez, V.C. Jones, M. Tabuchi, S.M. Allan, E.M. Knight, and F.M. LaFerla Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease PLoS ONE 3 2008 e2935
-
(2008)
PLoS ONE
, vol.3
, pp. 2935
-
-
Rodriguez, J.J.1
Jones, V.C.2
Tabuchi, M.3
Allan, S.M.4
Knight, E.M.5
Laferla, F.M.6
-
33
-
-
0036849021
-
Microglia and inflammatory mechanisms in the clearance of amyloid β peptide
-
J. Rogers, R. Strohmeyer, C.J. Kovelowski, and R. Li Microglia and inflammatory mechanisms in the clearance of amyloid β peptide Glia 40 2002 260 269
-
(2002)
Glia
, vol.40
, pp. 260-269
-
-
Rogers, J.1
Strohmeyer, R.2
Kovelowski, C.J.3
Li, R.4
-
34
-
-
34447261382
-
Cerebellar neurodegeneration in the absence of microRNAs
-
A. Schaefer, D. O'Carroll, C.L. Tan, D. Hillman, M. Sugimori, and R. Llinas Cerebellar neurodegeneration in the absence of microRNAs J Exp Med 204 2007 1553 1558
-
(2007)
J Exp Med
, vol.204
, pp. 1553-1558
-
-
Schaefer, A.1
O'Carroll, D.2
Tan, C.L.3
Hillman, D.4
Sugimori, M.5
Llinas, R.6
-
35
-
-
79959305691
-
Mitochondria: The next (neurode)generation
-
E.A. Schon, and S. Przedborski Mitochondria: the next (neurode)generation Neuron 70 2011 1033 1053
-
(2011)
Neuron
, vol.70
, pp. 1033-1053
-
-
Schon, E.A.1
Przedborski, S.2
-
36
-
-
84866456583
-
Preventing Alzheimer's disease
-
D.J. Selkoe Preventing Alzheimer's disease Science 337 2012 1488 1492
-
(2012)
Science
, vol.337
, pp. 1488-1492
-
-
Selkoe, D.J.1
-
37
-
-
0035868717
-
Neurogenesis in the adult is involved in the formation of trace memories
-
T.J. Shors, G. Miesegaes, A. Beylin, M. Zhao, T. Rydel, and E. Gould Neurogenesis in the adult is involved in the formation of trace memories Nature 410 2001 372 376
-
(2001)
Nature
, vol.410
, pp. 372-376
-
-
Shors, T.J.1
Miesegaes, G.2
Beylin, A.3
Zhao, M.4
Rydel, T.5
Gould, E.6
-
38
-
-
66949146836
-
Monocyte chemoattractant protein-1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease
-
A. Sokolova, M.D. Hill, F. Rahimi, L.A. Warden, G.M. Halliday, and C.E. Shepherd Monocyte chemoattractant protein-1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease Brain Pathol 19 2009 392 398
-
(2009)
Brain Pathol
, vol.19
, pp. 392-398
-
-
Sokolova, A.1
Hill, M.D.2
Rahimi, F.3
Warden, L.A.4
Halliday, G.M.5
Shepherd, C.E.6
-
39
-
-
66749185823
-
Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration
-
K. Tabuchi, G. Chen, T.C. Südhof, and J. Shen Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration J Neurosci 29 2009 7290 7301
-
(2009)
J Neurosci
, vol.29
, pp. 7290-7301
-
-
Tabuchi, K.1
Chen, G.2
Südhof, T.C.3
Shen, J.4
-
40
-
-
0030460425
-
Subregion- and cell type-restricted gene knockout in mouse brain
-
J.Z. Tsien, D.F. Chen, D. Gerber, C. Tom, E.H. Mercer, and D.J. Anderson Subregion- and cell type-restricted gene knockout in mouse brain Cell 87 1996 1317 1326
-
(1996)
Cell
, vol.87
, pp. 1317-1326
-
-
Tsien, J.Z.1
Chen, D.F.2
Gerber, D.3
Tom, C.4
Mercer, E.H.5
Anderson, D.J.6
-
41
-
-
77956322371
-
Characterization of age-dependent and progressive cortical neuronal degeneration in presenilin conditional mutant mice
-
M. Wines-Samuelson, E.C. Schulte, M.J. Smith, C. Aoki, X. Liu, and R.J. Kelleher Characterization of age-dependent and progressive cortical neuronal degeneration in presenilin conditional mutant mice PLoS ONE 5 2010 e10195
-
(2010)
PLoS ONE
, vol.5
, pp. 10195
-
-
Wines-Samuelson, M.1
Schulte, E.C.2
Smith, M.J.3
Aoki, C.4
Liu, X.5
Kelleher, R.J.6
|