Radiation promotes malignant progression of glioma cells through HIF-1alpha stabilization

Cancer Letters

Volumn 354, Issue 1, 2014, Pages 132-141

  Kim, Young Heon ^a   Yoo, Ki Chun ^a   Cui, Yan Hong ^a   Uddin, Nizam ^a   Lim, Eun Jung ^a   Kim, Min Jung ^b   Nam, Seon Young ^c   Kim, In Gyu ^d   Suh, Yongjoon ^a   Lee, Su Jae ^a  

^a Hanyang University   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c Korea Hydro & Nuclear Power Co   (South Korea)

^d Korea Atomic Energy Research Institute   (South Korea)

Author keywords

Angiogenesis; Hypoxia inducible factor 1 alpha; Infiltration of glioma cells; Ionizing radiation; P38 MAPK

Indexed keywords

BETA ACTIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; NERVE CELL ADHESION MOLECULE; VON HIPPEL LINDAU PROTEIN; COLLAGEN; EGLN1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1 ALPHA; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; LAMININ; MATRIGEL; PROTEOGLYCAN; UBIQUITIN PROTEIN LIGASE; VHL PROTEIN, HUMAN;

ARTICLE; CANCER GROWTH; CANCER INFILTRATION; CARCINOGENESIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GLIOMA CELL; HUMAN; HUMAN CELL; HYDROXYLATION; IMMUNOCYTOCHEMISTRY; IONIZING RADIATION; POLYMERIZATION; PROTEIN EXPRESSION; PROTEIN STABILITY; RADIATION EXPOSURE; TUMOR MICROENVIRONMENT; ANGIOGENESIS; BRAIN TUMOR; CELL MOTION; CHEMISTRY; DISEASE COURSE; DRUG COMBINATION; GLIOMA; INFILTRATION OF GLIOMA CELLS; METABOLISM; P38 MAPK; RADIATION DOSE FRACTIONATION; TIME; TUMOR CELL LINE; TUMOR INVASION;

ANGIOGENESIS; HYPOXIA INDUCIBLE FACTOR 1 ALPHA; INFILTRATION OF GLIOMA CELLS; IONIZING RADIATION; P38 MAPK;

BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN; DISEASE PROGRESSION; DOSE FRACTIONATION; DRUG COMBINATIONS; GLIOMA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; LAMININ; NEOPLASM INVASIVENESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEOGLYCANS; RADIATION, IONIZING; TIME FACTORS; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84909995987     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.07.048     Document Type: Article

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