-
1
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
H. Walczak, R.E. Miller, K. Ariail, B. Gliniak, T.S. Griffith, M. Kubin, W. Chin, J. Jones, A. Woodward, T. Le, C. Smith, P. Smolak, R.G. Goodwin, C.T. Rauch, J.C. Schuh, and D.H. Lynch Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo Nat. Med. 5 1999 157 163
-
(1999)
Nat. Med.
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
Chin, W.7
Jones, J.8
Woodward, A.9
Le, T.10
Smith, C.11
Smolak, P.12
Goodwin, R.G.13
Rauch, C.T.14
Schuh, J.C.15
Lynch, D.H.16
-
2
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
A. Ashkenazi Targeting death and decoy receptors of the tumour-necrosis factor superfamily Nat. Rev. Cancer 2 2002 420 430
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 420-430
-
-
Ashkenazi, A.1
-
3
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
A. Ashkenazi, R.C. Pai, S. Fong, S. Leung, D.A. Lawrence, S.A. Marsters, C. Blackie, L. Chang, A.E. McMurtrey, A. Hebert, L. DeForge, I.L. Koumenis, D. Lewis, L. Harris, J. Bussiere, H. Koeppen, Z. Shahrokh, and R.H. Schwall Safety and antitumor activity of recombinant soluble Apo2 ligand J. Clin. Invest. 104 1999 155 162
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
Blackie, C.7
Chang, L.8
McMurtrey, A.E.9
Hebert, A.10
Deforge, L.11
Koumenis, I.L.12
Lewis, D.13
Harris, L.14
Bussiere, J.15
Koeppen, H.16
Shahrokh, Z.17
Schwall, R.H.18
-
4
-
-
24944458177
-
Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: Induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death
-
G.V. Georgakis, Y. Li, R. Humphreys, M. Andreeff, S. O'Brien, M. Younes, A. Carbone, V. Albert, and A. Younes Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death Br. J. Haematol. 130 2005 501 510
-
(2005)
Br. J. Haematol.
, vol.130
, pp. 501-510
-
-
Georgakis, G.V.1
Li, Y.2
Humphreys, R.3
Andreeff, M.4
O'Brien, S.5
Younes, M.6
Carbone, A.7
Albert, V.8
Younes, A.9
-
5
-
-
21044441651
-
HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo
-
L. Pukac, P. Kanakaraj, R. Humphreys, R. Alderson, M. Bloom, C. Sung, T. Riccobene, R. Johnson, M. Fiscella, A. Mahoney, J. Carrell, E. Boyd, X.T. Yao, L. Zhang, L. Zhong, A. von Kerczek, L. Shepard, T. Vaughan, B. Edwards, C. Dobson, T. Salcedo, and V. Albert HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo Br. J. Cancer 92 2005 1430 1441
-
(2005)
Br. J. Cancer
, vol.92
, pp. 1430-1441
-
-
Pukac, L.1
Kanakaraj, P.2
Humphreys, R.3
Alderson, R.4
Bloom, M.5
Sung, C.6
Riccobene, T.7
Johnson, R.8
Fiscella, M.9
Mahoney, A.10
Carrell, J.11
Boyd, E.12
Yao, X.T.13
Zhang, L.14
Zhong, L.15
Von Kerczek, A.16
Shepard, L.17
Vaughan, T.18
Edwards, B.19
Dobson, C.20
Salcedo, T.21
Albert, V.22
more..
-
6
-
-
78649616252
-
Generation of TRAIL-receptor 1-specific human monoclonal Ab by a combination of immunospot array assay on a chip and human Ab-producing mice
-
A. Jin, T. Ozawa, K. Tajiri, Z. Lin, T. Obata, I. Ishida, H. Kishi, and A. Muraguchi Generation of TRAIL-receptor 1-specific human monoclonal Ab by a combination of immunospot array assay on a chip and human Ab-producing mice Eur. J. Immunol. 40 2010 3591 3593
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 3591-3593
-
-
Jin, A.1
Ozawa, T.2
Tajiri, K.3
Lin, Z.4
Obata, T.5
Ishida, I.6
Kishi, H.7
Muraguchi, A.8
-
7
-
-
0036241369
-
Production of human monoclonal and polyclonal antibodies in TransChromo animals
-
I. Ishida, K. Tomizuka, H. Yoshida, T. Tahara, N. Takahashi, A. Ohguma, S. Tanaka, M. Umehashi, H. Maeda, C. Nozaki, E. Halk, and N. Lonberg Production of human monoclonal and polyclonal antibodies in TransChromo animals Cloning Stem Cells 4 2002 91 102
-
(2002)
Cloning Stem Cells
, vol.4
, pp. 91-102
-
-
Ishida, I.1
Tomizuka, K.2
Yoshida, H.3
Tahara, T.4
Takahashi, N.5
Ohguma, A.6
Tanaka, S.7
Umehashi, M.8
Maeda, H.9
Nozaki, C.10
Halk, E.11
Lonberg, N.12
-
9
-
-
65249101637
-
The promise and potential pitfalls of chimeric antigen receptors
-
M. Sadelain, R. Brentjens, and I. Riviere The promise and potential pitfalls of chimeric antigen receptors Curr. Opin. Immunol. 21 2009 215 223
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 215-223
-
-
Sadelain, M.1
Brentjens, R.2
Riviere, I.3
-
10
-
-
0024834988
-
Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity
-
G. Gross, T. Waks, and Z. Eshhar Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity Proc. Natl. Acad. Sci. U.S.A. 86 1989 10024 10028
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 10024-10028
-
-
Gross, G.1
Waks, T.2
Eshhar, Z.3
-
11
-
-
84859590944
-
Single-chain ValphaVbeta T-cell receptors function without mispairing with endogenous TCR chains
-
D.H. Aggen, A.S. Chervin, T.M. Schmitt, B. Engels, J.D. Stone, S.A. Richman, K.H. Piepenbrink, B.M. Baker, P.D. Greenberg, H. Schreiber, and D.M. Kranz Single-chain ValphaVbeta T-cell receptors function without mispairing with endogenous TCR chains Gene Ther. 19 2012 365 374
-
(2012)
Gene Ther.
, vol.19
, pp. 365-374
-
-
Aggen, D.H.1
Chervin, A.S.2
Schmitt, T.M.3
Engels, B.4
Stone, J.D.5
Richman, S.A.6
Piepenbrink, K.H.7
Baker, B.M.8
Greenberg, P.D.9
Schreiber, H.10
Kranz, D.M.11
-
12
-
-
34848842554
-
Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts
-
R.J. Brentjens, E. Santos, Y. Nikhamin, R. Yeh, M. Matsushita, K. La Perle, A. Quintas-Cardama, S.M. Larson, and M. Sadelain Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts Clin. Cancer Res. 13 2007 5426 5435
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5426-5435
-
-
Brentjens, R.J.1
Santos, E.2
Nikhamin, Y.3
Yeh, R.4
Matsushita, M.5
La Perle, K.6
Quintas-Cardama, A.7
Larson, S.M.8
Sadelain, M.9
-
13
-
-
84878921225
-
A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell engagers (BiTEs)
-
J.D. Stone, D.H. Aggen, A. Schietinger, H. Schreiber, and D.M. Kranz A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell engagers (BiTEs) Oncoimmunology 1 2012 863 873
-
(2012)
Oncoimmunology
, vol.1
, pp. 863-873
-
-
Stone, J.D.1
Aggen, D.H.2
Schietinger, A.3
Schreiber, H.4
Kranz, D.M.5
-
14
-
-
77951622836
-
Post-translational modification of TRAIL receptor type 1 on various tumor cells and the susceptibility of tumors to TRAIL-induced apoptosis
-
Z. Lin, A. Jin, T. Ozawa, K. Tajiri, T. Obata, I. Ishida, F. Jin, H. Kishi, and A. Muraguchi Post-translational modification of TRAIL receptor type 1 on various tumor cells and the susceptibility of tumors to TRAIL-induced apoptosis Biochem. Biophys. Res. Commun. 395 2010 251 257
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.395
, pp. 251-257
-
-
Lin, Z.1
Jin, A.2
Ozawa, T.3
Tajiri, K.4
Obata, T.5
Ishida, I.6
Jin, F.7
Kishi, H.8
Muraguchi, A.9
-
15
-
-
84887445200
-
A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days
-
E. Kobayashi, E. Mizukoshi, H. Kishi, T. Ozawa, H. Hamana, T. Nagai, H. Nakagawa, A. Jin, S. Kaneko, and A. Muraguchi A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days Nat. Med. 19 2013 1542 1546
-
(2013)
Nat. Med.
, vol.19
, pp. 1542-1546
-
-
Kobayashi, E.1
Mizukoshi, E.2
Kishi, H.3
Ozawa, T.4
Hamana, H.5
Nagai, T.6
Nakagawa, H.7
Jin, A.8
Kaneko, S.9
Muraguchi, A.10
-
16
-
-
0031405585
-
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB
-
P. Schneider, M. Thome, K. Burns, J.L. Bodmer, K. Hofmann, T. Kataoka, N. Holler, and J. Tschopp TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB Immunity 7 1997 831 836
-
(1997)
Immunity
, vol.7
, pp. 831-836
-
-
Schneider, P.1
Thome, M.2
Burns, K.3
Bodmer, J.L.4
Hofmann, K.5
Kataoka, T.6
Holler, N.7
Tschopp, J.8
-
17
-
-
0029055757
-
Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells
-
S. Shresta, D.M. MacIvor, J.W. Heusel, J.H. Russell, and T.J. Ley Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells Proc. Natl. Acad. Sci. U.S.A. 92 1995 5679 5683
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 5679-5683
-
-
Shresta, S.1
Macivor, D.M.2
Heusel, J.W.3
Russell, J.H.4
Ley, T.J.5
-
18
-
-
0028947976
-
Perforin and granzymes: Crucial effector molecules in cytolytic T lymphocyte and natural killer cell-mediated cytotoxicity
-
B. Lowin, M.C. Peitsch, and J. Tschopp Perforin and granzymes: crucial effector molecules in cytolytic T lymphocyte and natural killer cell-mediated cytotoxicity Curr. Top. Microbiol. Immunol. 198 1995 1 24
-
(1995)
Curr. Top. Microbiol. Immunol.
, vol.198
, pp. 1-24
-
-
Lowin, B.1
Peitsch, M.C.2
Tschopp, J.3
-
19
-
-
84879887781
-
Cleavage of the interchain disulfide bonds in rituximab increases its affinity for FcgammaRIIIA
-
M. Suzuki, A. Yamanoi, Y. Machino, E. Kobayashi, K. Fukuchi, M. Tsukimoto, S. Kojima, J. Kohroki, K. Akimoto, and Y. Masuho Cleavage of the interchain disulfide bonds in rituximab increases its affinity for FcgammaRIIIA Biochem. Biophys. Res. Commun. 436 2013 519 524
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.436
, pp. 519-524
-
-
Suzuki, M.1
Yamanoi, A.2
Machino, Y.3
Kobayashi, E.4
Fukuchi, K.5
Tsukimoto, M.6
Kojima, S.7
Kohroki, J.8
Akimoto, K.9
Masuho, Y.10
-
20
-
-
0023707073
-
Circulating cytokines in patients with metastatic cancer treated with recombinant interleukin 2 and lymphokine-activated killer cells
-
B.T. Gemlo, M.A. Palladino Jr., H.S. Jaffe, T.P. Espevik, and A.A. Rayner Circulating cytokines in patients with metastatic cancer treated with recombinant interleukin 2 and lymphokine-activated killer cells Cancer Res. 48 1988 5864 5867
-
(1988)
Cancer Res.
, vol.48
, pp. 5864-5867
-
-
Gemlo, B.T.1
Palladino, M.A.2
Jaffe, H.S.3
Espevik, T.P.4
Rayner, A.A.5
-
21
-
-
77953647938
-
The optimal antigen response of chimeric antigen receptors harboring the CD3zeta transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex
-
J.S. Bridgeman, R.E. Hawkins, S. Bagley, M. Blaylock, M. Holland, and D.E. Gilham The optimal antigen response of chimeric antigen receptors harboring the CD3zeta transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex J. Immunol. 184 2010 6938 6949
-
(2010)
J. Immunol.
, vol.184
, pp. 6938-6949
-
-
Bridgeman, J.S.1
Hawkins, R.E.2
Bagley, S.3
Blaylock, M.4
Holland, M.5
Gilham, D.E.6
-
22
-
-
78650970845
-
Innate or adaptive immunity? the example of natural killer cells
-
E. Vivier, D.H. Raulet, A. Moretta, M.A. Caligiuri, L. Zitvogel, L.L. Lanier, W.M. Yokoyama, and S. Ugolini Innate or adaptive immunity? The example of natural killer cells Science 331 2011 44 49
-
(2011)
Science
, vol.331
, pp. 44-49
-
-
Vivier, E.1
Raulet, D.H.2
Moretta, A.3
Caligiuri, M.A.4
Zitvogel, L.5
Lanier, L.L.6
Yokoyama, W.M.7
Ugolini, S.8
-
23
-
-
0034881279
-
Cellular immunotherapy of malignancies using the clonal natural killer cell line NK-92
-
T. Tonn, S. Becker, R. Esser, D. Schwabe, and E. Seifried Cellular immunotherapy of malignancies using the clonal natural killer cell line NK-92 J. Hematother. Stem Cell Res. 10 2001 535 544
-
(2001)
J. Hematother. Stem Cell Res.
, vol.10
, pp. 535-544
-
-
Tonn, T.1
Becker, S.2
Esser, R.3
Schwabe, D.4
Seifried, E.5
|