Crystal structure of active site mutant of antileukemic L-asparaginase reveals conserved zinc-binding site

The FEBS journal

Volumn 281, Issue 18, 2014, Pages 4097-4111

  Borek, Dominika ^a   Kozak, Maciej ^a   Pei, Jimin ^a   Jaskolski, Mariusz ^a  

^a ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

acute lymphoblastic leukemia; l asparaginase; mutation; pancreatitis; zinc binding site

Indexed keywords

ASPARAGINASE; COORDINATION COMPOUND; ZINC;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; HYDROGEN BOND; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ASPARAGINASE; CATALYTIC DOMAIN; CONSERVED SEQUENCE; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; ZINC;

EID: 84909982782     PISSN: None     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12906     Document Type: Article

References (0)