β-Lactam Antibiotics

Encyclopedia of Microbiology, Third Edition

Volumn , Issue , 2009, Pages 274-289

  Liras, P ^a   Martin J F ^a  

^a UNIVERSITY OF LEÓN   (Spain)

Author keywords

antibiotics; carbapenems; cephabacins; cephalosporins; cephamycins; clavams; clavulanic acid; monobactams; nocardicins; penicillins; lactams

Indexed keywords

EID: 84909963108     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012373944-5.00039-0     Document Type: Chapter

References (14)

1. Y. Aharonowitz, G. Cohen and J.F. Martín (1992) Penicillin and cephalosporin biosynthetic genes: Structure, organization, regulation, and evolution. Annual Review of Microbiology 46 461-495
2. K.H. Baggaley, A.G. Brown and C.J. Schofield (1997) Chemistry and biosynthesis of clavulanic acid and other clavams. Natural Product Reports 140 309-333
3. M. Bibb (1996) The regulation of antibiotic production in Streptomyces coelicolor A3(2). Microbiology 142 1335-1344
4. A.A. Brakhage (1998) Molecular regulation of beta-lactam biosynthesis in filamentous fungi. Microbiology and Molecular Biology Reviews 62 547-585
5. S.J. Coulthurst, A.M. Barnard and G.P. Salmond (2005) Regulation and biosynthesis of carbapenem antibiotics in bacteria. Nature Reviews Microbiology 3 295-306
6. B. Díez, E. Mellado, M. Rodríguez, R. Fouces and J.L. Barredo (1997) Recombinant microorganisms for industrial production of antibiotics. Biotechnology and Bioengineering 55 216-226
7. P. Liras (1999) Biosynthesis and molecular genetics of cephamycins. Cephamycins produced by actinomycetes. Antonie Van Leeuwenhoek 75 109-124
8. P. Liras and A. Rodríguez-García (2000) Clavulanic acid, a beta-lactamase inhibitor: Biosynthesis and molecular genetics. Applied Microbiology and Biotechnology 54 467-475
9. J.F. Martín (1998) New aspects of gene and enzymes for β-lactam antibiotic biosynthesis. Applied Microbiology and Biotechnology 50 1-15
10. J.F. Martín (2000) Alpha-aminoadipyl-cysteinyl-valine synthetases in beta-lactam producing organisms. From Abraham's discoveries to novel concepts of non-ribosomal peptide synthesis. The Journal of Antibiotics 53 1008-1021
11. J.F. Martín (2000) Molecular control of expression of penicillin biosynthesis genes in fungi: Regulatory proteins interact with a bidirectional promoter region. Journal of Bacteriology 182 2355-2362
12. J.F. Martín, J. Casqueiro and P. Liras (2005) Secretion systems for secondary metabolites: How producer cells send out messages of intercellular communication. Current Opinion in Microbiology 8 282-293
13. J.F. Martín, S. Gutiérrez and J.F. Aparicio (2000) Secondary metabolites. J. Lederberg (Eds) 2nd edn. Encyclopedia of Microbiology vol. 4 San Diego, CA: Academic Press 213-236
14. J.F. Martín, R.V. Ullán and F.J. Casqueiro (2004) Novel genes involved in cephalosporin biosynthesis: The three-component isopenicillin N epimerase system. A. Brakhage (Eds) Advances in Biochemical Engineering-Biotechnology Berlin: Springer-Verlag 91-109