메뉴 건너뛰기




Volumn 34, Issue 3, 2014, Pages 433-446

Trends in antibiotic resistance in Medellín and municipalities of the Metropolitan Area between 2007 and 2012: Results of six years of surveillance;Tendencias de la resistencia a antibióticos en Medellín y en los municipios del área metropolitana entre 2007 y 2012: Resultados de seis años de vigilancia

(65)  Maldonado, Natalia Andrea a   Múnera, María Isabel b   López, Jaime Alberto c   Sierra, Patricia d,q   Robledo, Carlos a   Robledo, Jaime a,e,f   Robledo, Carlos G a   Arroyave, Luz Beatriz a   Giraldo, Luz Teresita a   Maldonado, Natalia A a   Bedoya, Ana María b   Cuartas, Mónica b   Molina, Olga b   Restrepo, Ana b   Marín, Gloria b   Franco, Liliana g   Roncancio, Gustavo g   González, Juan Carlos g   Romero, Liliana g   Gallo, Martha g   more..


Author keywords

Drug resistance; Enterobacteriaceae; Epidemiological surveillance; Methicillin resistant Staphylococcus aureus; Pseudomonas aeruginosa; Vancomycin resistance

Indexed keywords

ACINETOBACTER BAUMANNII; BACTERIA (MICROORGANISMS); ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; PSEUDOMONAS AERUGINOSA; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS;

EID: 84909643565     PISSN: 01204157     EISSN: None     Source Type: Journal    
DOI: 10.7705/biomedica.v34i3.1658     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 84909618265 scopus 로고    scopus 로고
    • Fifty-first World Assembly, Emerging and other communicable diseases: Antimicrobial resistance - 1998
    • Fecha de consulta: 8 de mayo de 2013. Disponible en
    • World Health Organization. Fifty-first World Assembly, Emerging and other communicable diseases: Antimicrobial resistance - 1998. Fecha de consulta: 8 de mayo de 2013. Disponible en: http://apps.who.int/medicinedocs/documents/s16334e/s16334e.pdf.
  • 2
    • 65749083681 scopus 로고    scopus 로고
    • Annual Epidemiological Report on Communicable Diseases in Europe - 2010
    • Fecha de consulta: 8 de mayo de 2013. Disponible en
    • European Centre for Disease Prevention and Control (ECDC). Annual Epidemiological Report on Communicable Diseases in Europe - 2010. Fecha de consulta: 8 de mayo de 2013. Disponible en: http://www.ecdc.europa.eu/en/publications/publications/1011_sur_annual_epidemiological_report_on_communicable_diseases_in_europe.pdf.
  • 3
    • 84909586956 scopus 로고    scopus 로고
    • Estrategia Mundial de la OMS para Contener la Resistencia a los Antimicrobianos - 2001
    • Fecha de consulta: 4 de mayo de 2013. Disponible en
    • Organización Mundial de la Salud. Estrategia Mundial de la OMS para Contener la Resistencia a los Antimicrobianos - 2001. Fecha de consulta: 4 de mayo de 2013. Disponible en: http://www.who.int/drugresistance/SpGlobal2.pdf?ua=1.
  • 4
    • 84909642633 scopus 로고    scopus 로고
    • Informe científico de la Red. Estado del arte de la resistencia bacteriana y de la vigilancia epidemiológica de las infecciones asociadas al cuidado de la salud en Colombia
    • Fecha de consulta: 20 de abril de 2013. Disponible en
    • Ministerio de la Protección Social - República de Colombia. Informe científico de la Red. Estado del arte de la resistencia bacteriana y de la vigilancia epidemiológica de las infecciones asociadas al cuidado de la salud en Colombia. Fecha de consulta: 20 de abril de 2013. Disponible en: http://www.ins.gov.co/temas-de-interes/IAAS/4.%20Estado%20del%20arte%20de%20resistencia%20bacteriana.pdf.
  • 5
    • 84893306290 scopus 로고    scopus 로고
    • ¿Qué es la Red PREVINS?
    • Fecha de consulta: 5 de abril de 2013. Disponible en
    • Instituto Nacional de Salud. ¿Qué es la Red PREVINS? Fecha de consulta: 5 de abril de 2013. Disponible en: www.ins.gov.co/iaas/Paginas/que-es-la-RED-PREVINS.aspx.
  • 7
    • 78649654921 scopus 로고    scopus 로고
    • Intercontinental spread from Israel to Colombia of a KPC-3-producing Klebsiella pneumoniae strain
    • López JA, Correa A, Navon-Venezia S, Correa AL, Torres JA, Briceño DF, et al. Intercontinental spread from Israel to Colombia of a KPC-3-producing Klebsiella pneumoniae strain. Clin Microbiol Infect. 2011;17:52-6. http://dx.doi.org/10.1111/j.1469-0691.2010.03209.x
    • (2011) Clin Microbiol Infect. , vol.17 , pp. 52-56
    • López, J.A.1    Correa, A.2    Navon-Venezia, S.3    Correa, A.L.4    Torres, J.A.5    Briceño, D.F.6
  • 8
    • 80054690178 scopus 로고    scopus 로고
    • Wide dissemination of Pseudomonas aeruginosa producing beta-lactamase blaKPC-2 gene in Colombia
    • Cuzon G, Naas T, Villegas MV, Correa A, Quinn JP, Nordmann P. Wide dissemination of Pseudomonas aeruginosa producing beta-lactamase blaKPC-2 gene in Colombia. Antimicrob Agents Chemother. 2011;55:5350-3. http://dx.doi/10.1128/AAC.00297-11
    • (2011) Antimicrob Agents Chemother. , vol.55 , pp. 5350-5353
    • Cuzon, G.1    Naas, T.2    Villegas, M.V.3    Correa, A.4    Quinn, J.P.5    Nordmann, P.6
  • 9
    • 34247178075 scopus 로고    scopus 로고
    • First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase
    • Villegas MV, Lolans K, Correa A, Kattan JN, López JA, Quinn JP. First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. Antimicrob Agents Chemother. 2007;51:1553-5. http://dx.doi:10.1128/AAC.01405-06
    • (2007) Antimicrob Agents Chemother. , vol.51 , pp. 1553-1555
    • Villegas, M.V.1    Lolans, K.2    Correa, A.3    Kattan, J.N.4    López, J.A.5    Quinn, J.P.6
  • 11
    • 0005472344 scopus 로고    scopus 로고
    • Analysis and presentation of cumulative antimicrobial susceptibility test data; approved guideline. Fourth edition
    • CLSI document M39-A4. Wayne, PA: CLSI
    • Clinical and Laboratory Standards Institute. Analysis and presentation of cumulative antimicrobial susceptibility test data; approved guideline. Fourth edition. CLSI document M39-A4. Wayne, PA: CLSI; 2014.
    • (2014)
  • 12
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America
    • Boucher HW, Talbot GH, Bradley JS, Edwards JE, Gilbert D, Rice LB, et al. Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis. 2009;48:1-12. http://dx.doi.org/10.1086/595011
    • (2009) Clin Infect Dis. , vol.48 , pp. 1-12
    • Boucher, H.W.1    Talbot, G.H.2    Bradley, J.S.3    Edwards, J.E.4    Gilbert, D.5    Rice, L.B.6
  • 13
    • 65349084964 scopus 로고    scopus 로고
    • Performance standards for antimicrobial susceptibility testing; Nineteenth Informational Supplement
    • CLSI document M100-S19. Wayne, PA: CLSI
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; Nineteenth Informational Supplement. CLSI document M100-S19. Wayne, PA: CLSI; 2009.
    • (2009)
  • 14
    • 84891742685 scopus 로고    scopus 로고
    • Performance standards for antimicrobial susceptibility testing; Twenty-Third Informational Supplement
    • CLSI document M100-S23. Wayne, PA: CLSI
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; Twenty-Third Informational Supplement. CLSI document M100-S23. Wayne, PA: CLSI; 2013.
    • (2013)
  • 15
    • 84909583649 scopus 로고    scopus 로고
    • Resultados del Proyecto: "Impacto clínico y económico de la resistencia bacteriana en hospitales del Distrito"
    • Fecha de consulta: 8 de marzo de 2014. Disponible en
    • Grupo para el Control de la Resistencia Bacteriana de Bogotá - GREBO. Resultados del Proyecto: "Impacto clínico y económico de la resistencia bacteriana en hospitales del Distrito". Fecha de consulta: 8 de marzo de 2014. Disponible en: http://grebo.org/grebo_site/jgrebo/documentos/Boletin%20Informativo%20No%20S1%202010.pdf.
  • 16
    • 84873154771 scopus 로고    scopus 로고
    • Changes in Staphylo-coccus aureus susceptibility across Latin America between 2004 and 2010
    • Garza-González E, Dowzicky MJ. Changes in Staphylo-coccus aureus susceptibility across Latin America between 2004 and 2010. Braz J Infect Dis. 2013;17:13-9. http://dx.doi.org/10.1016/j.bjid.2012.08.017
    • (2013) Braz J Infect Dis. , vol.17 , pp. 13-19
    • Garza-González, E.1    Dowzicky, M.J.2
  • 17
    • 84886924257 scopus 로고    scopus 로고
    • Trends in antibiotic resistance over time among pathogens from Canadian hospitals: Results of the CANWARD study 2007-11
    • Lagacé-Wiens PR, Adam HJ, Low DE, Blondeau JM, Baxter MR, Denisuik AJ, et al. Trends in antibiotic resistance over time among pathogens from Canadian hospitals: Results of the CANWARD study 2007-11. J Antimicrob Chemother. 2013;68:23-9. http://dx.doi.org/10.1093/jac/dkt023
    • (2013) J Antimicrob Chemother. , vol.68 , pp. 23-29
    • Lagacé-Wiens, P.R.1    Adam, H.J.2    Low, D.E.3    Blondeau, J.M.4    Baxter, M.R.5    Denisuik, A.J.6
  • 18
    • 84858278979 scopus 로고    scopus 로고
    • Fourteen years in resistance
    • Livermore DM. Fourteen years in resistance. Int J Antimicrob Agents. 2012;39:283-94. http://dx.doi.org/10.1016/j.ijantimicag.2011.12.012
    • (2012) Int J Antimicrob Agents. , vol.39 , pp. 283-294
    • Livermore, D.M.1
  • 19
    • 84858282256 scopus 로고    scopus 로고
    • Meticillin-resistant Staphylococcus aureus (MRSA): Global epidemiology and harmonization of typing methods
    • Stefani S, Chung DR, Lindsay JA, Friedrich AW, Kearns AM, Westh H, et al. Meticillin-resistant Staphylococcus aureus (MRSA): Global epidemiology and harmonization of typing methods. Int J Antimicrob Agents. 2012;39:273-82. http://dx.doi.org/10.1016/j.ijantimicag.2011.09.030
    • (2012) Int J Antimicrob Agents. , vol.39 , pp. 273-282
    • Stefani, S.1    Chung, D.R.2    Lindsay, J.A.3    Friedrich, A.W.4    Kearns, A.M.5    Westh, H.6
  • 20
    • 84856809233 scopus 로고    scopus 로고
    • Reduced vancomycin susceptibility among clinical Staphylococcus aureus isolates ('the MIC Creep'): Implications for therapy
    • Dhand A, Sakoulas G. Reduced vancomycin susceptibility among clinical Staphylococcus aureus isolates ('the MIC Creep'): Implications for therapy. F1000 Med Rep. 2012;4:4. http://dx.doi.org/10.3410/M4-4
    • (2012) F1000 Med Rep. , vol.4 , pp. 4
    • Dhand, A.1    Sakoulas, G.2
  • 21
    • 84856140956 scopus 로고    scopus 로고
    • Revisión sistemática de la resistencia antimicrobiana en cocos Gram positivos intrahospitalarios en Colombia
    • Espinosa CJ, Cortés JA, Castillo JA, Leal AL. Revisión sistemática de la resistencia antimicrobiana en cocos Gram positivos intrahospitalarios en Colombia. Biomédica. 2011; 31:27-34. http://dx.doi.org/10.7705/biomedica.v31i1.333
    • (2011) Biomédica. , vol.31 , pp. 27-34
    • Espinosa, C.J.1    Cortés, J.A.2    Castillo, J.A.3    Leal, A.L.4
  • 22
    • 77951820301 scopus 로고    scopus 로고
    • Molecular epidemiology of vancomycin-resistant Enterococcus faecium: A prospective, multicenter study in South American hospitals
    • Panesso D, Reyes J, Rincón S, Díaz L, Galloway-Peña J, Zurita J, et al. Molecular epidemiology of vancomycin-resistant Enterococcus faecium: A prospective, multicenter study in South American hospitals. J Clin Microbiol. 2010;48:1562-9. http://dx.doi.org/10.1128/JCM.02526-09
    • (2010) J Clin Microbiol. , vol.48 , pp. 1562-1569
    • Panesso, D.1    Reyes, J.2    Rincón, S.3    Díaz, L.4    Galloway-Peña, J.5    Zurita, J.6
  • 23
    • 76649105136 scopus 로고    scopus 로고
    • Antimicrobial susceptibility of gram-positive bacteria isolated in Brazilian hospitals participating in the SENTRY Program (2005-2008)
    • Gales AC, Sader HS, Ribeiro J, Zoccoli C, Barth A, Pignatari AC. Antimicrobial susceptibility of gram-positive bacteria isolated in Brazilian hospitals participating in the SENTRY Program (2005-2008). Braz J Infect Dis. 2009;13:90-8. http://dx.doi.org/10.1590/S1413-86702009000200004
    • (2009) Braz J Infect Dis. , vol.13 , pp. 90-98
    • Gales, A.C.1    Sader, H.S.2    Ribeiro, J.3    Zoccoli, C.4    Barth, A.5    Pignatari, A.C.6
  • 24
    • 78650061835 scopus 로고    scopus 로고
    • Grupo de Resistencia Bacteriana Nosocomial de Colombia. Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia: años 2006, 2007 y 2008
    • Briceño DF, Correa A, Valencia C, Torres JA, Pacheco R, Montealegre MC, et al. Grupo de Resistencia Bacteriana Nosocomial de Colombia. Actualización de la resistencia a antimicrobianos de bacilos Gram negativos aislados en hospitales de nivel III de Colombia: años 2006, 2007 y 2008. Biomédica 2010;30:371-81. http://dx.doi.org/10.7705/biomedica.v30i3.271
    • (2010) Biomédica , vol.30 , pp. 371-381
    • Briceño, D.F.1    Correa, A.2    Valencia, C.3    Torres, J.A.4    Pacheco, R.5    Montealegre, M.C.6
  • 25
    • 38349182898 scopus 로고    scopus 로고
    • El Programa de Vigilancia Antimicrobiana SENTRY en Colombia, hallazgos iniciales en tres hospitales de Medellín
    • Robledo J, López J, Sierra P, Robledo C, Pfaller M, Jones RN. El Programa de Vigilancia Antimicrobiana SENTRY en Colombia, hallazgos iniciales en tres hospitales de Medellín. Infectio. 1999;3:100-7.
    • (1999) Infectio. , vol.3 , pp. 100-107
    • Robledo, J.1    López, J.2    Sierra, P.3    Robledo, C.4    Pfaller, M.5    Jones, R.N.6
  • 26
    • 3042792379 scopus 로고    scopus 로고
    • Prevalence and characterization of extended-spectrum beta-lactamases in Klebsiella pneumoniae and Escherichia coli isolates from Colombian hospitals
    • Villegas MV, Correa A, Pérez F, Miranda MC, Zuluaga T, Quinn JP, et al. Prevalence and characterization of extended-spectrum beta-lactamases in Klebsiella pneumoniae and Escherichia coli isolates from Colombian hospitals. Diagn Microbiol Infect Dis. 2004;49:217-22.
    • (2004) Diagn Microbiol Infect Dis. , vol.49 , pp. 217-222
    • Villegas, M.V.1    Correa, A.2    Pérez, F.3    Miranda, M.C.4    Zuluaga, T.5    Quinn, J.P.6
  • 27
    • 79955972175 scopus 로고    scopus 로고
    • Increasing prevalence of extended-spectrum-betalactamase among Gram-negative bacilli in Latin America - 2008 update from the Study for Monitoring Antimicrobial Resistance Trends (SMART)
    • Villegas MV, Blanco MG, Sifuentes-Osornio J, Rossi F. Increasing prevalence of extended-spectrum-betalactamase among Gram-negative bacilli in Latin America - 2008 update from the Study for Monitoring Antimicrobial Resistance Trends (SMART). Braz J Infect Dis. 2011;15:34-9. http://dx.doi.org/10.1590/S1413-86702011000100007
    • (2011) Braz J Infect Dis. , vol.15 , pp. 34-39
    • Villegas, M.V.1    Blanco, M.G.2    Sifuentes-Osornio, J.3    Rossi, F.4
  • 28
    • 79953875949 scopus 로고    scopus 로고
    • The challenges of antimicrobial resistance in Brazil
    • Rossi F. The challenges of antimicrobial resistance in Brazil. Clin Infect Dis. 2011;52:1138-43. http://dx.doi.org/10.1093/cid/cir120
    • (2011) Clin Infect Dis. , vol.52 , pp. 1138-1143
    • Rossi, F.1
  • 29
    • 84862605718 scopus 로고    scopus 로고
    • ESBLs: A clear and present danger?
    • Dhillon RH, Clark J. ESBLs: A clear and present danger? Crit Care Res Pract. 2012;2012:625170. http://dx.doi.org/10.1155/2012/625170
    • (2012) Crit Care Res Pract , vol.2012 , pp. 625170
    • Dhillon, R.H.1    Clark, J.2
  • 30
    • 84904389337 scopus 로고    scopus 로고
    • Revisión sistemática de la resis-tencia antimicrobiana en enterobacterias en aislamientos intrahospitalarios en Colombia
    • González L, Cortés JA. Revisión sistemática de la resis-tencia antimicrobiana en enterobacterias en aislamientos intrahospitalarios en Colombia. Biomédica. 2014;34:180-97. http://dx.doi.org/10.7705/biomedica.v34i2.1550
    • (2014) Biomédica. , vol.34 , pp. 180-197
    • González, L.1    Cortés, J.A.2
  • 31
    • 59749088655 scopus 로고    scopus 로고
    • First report on a hyperepidemic clone of KPC-3-producing Klebsiella pneumoniae in Israel genetically related to a strain causing outbreaks in the United States
    • Navon-Venezia S, Leavitt A, Schwaber MJ, Rasheed JK, Srinivasan A, Patel JB, et al. First report on a hyperepidemic clone of KPC-3-producing Klebsiella pneumoniae in Israel genetically related to a strain causing outbreaks in the United States. Antimicrob Agents Chemother. 2009;53:818-20. http://dx.doi.org/10.1128/AAC.00987-08
    • (2009) Antimicrob Agents Chemother. , vol.53 , pp. 818-820
    • Navon-Venezia, S.1    Leavitt, A.2    Schwaber, M.J.3    Rasheed, J.K.4    Srinivasan, A.5    Patel, J.B.6
  • 32
    • 62749195559 scopus 로고    scopus 로고
    • The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
    • Nordmann P, Cuzon G, Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis. 2009;9:228-36. http://dx.doi.org/10.1016/S1473-3099(09)70054-4
    • (2009) Lancet Infect Dis. , vol.9 , pp. 228-236
    • Nordmann, P.1    Cuzon, G.2    Naas, T.3
  • 33
    • 33746933470 scopus 로고    scopus 로고
    • First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America
    • Villegas MV, Lolans K, Correa A, Suárez CJ, López JA, Vallejo M, et al. First detection of the plasmid-mediated class A carbapenemase KPC-2 in clinical isolates of Klebsiella pneumoniae from South America. Antimicrob Agents Chemother. 2006;50:2880-2. http://dx.doi.org/10.1128/AAC.00186-06
    • (2006) Antimicrob Agents Chemother. , vol.50 , pp. 2880-2882
    • Villegas, M.V.1    Lolans, K.2    Correa, A.3    Suárez, C.J.4    López, J.A.5    Vallejo, M.6
  • 35
    • 44449165917 scopus 로고    scopus 로고
    • Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing ß-lactamase KPC-2 in intensive care units of a Chinese hospital
    • Cai JC, Zhou HW, Zhang R, Chen GX. Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing ß-lactamase KPC-2 in intensive care units of a Chinese hospital. Antimicrob Agents Chemother 2008;52:2014-8. http://dx.doi.org/10.1128/AAC.01539-07
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2014-2018
    • Cai, J.C.1    Zhou, H.W.2    Zhang, R.3    Chen, G.X.4
  • 36
    • 45149091874 scopus 로고    scopus 로고
    • Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid
    • Rasheed JK, Biddle JW, Anderson KF, Washer L, Chenoweth C, Perrin J, et al. Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid. J Clin Microbiol 2008; 46:2066-9. http://dx.doi.org/10.1128/JCM.02038-07
    • (2008) J Clin Microbiol , vol.46 , pp. 2066-2069
    • Rasheed, J.K.1    Biddle, J.W.2    Anderson, K.F.3    Washer, L.4    Chenoweth, C.5    Perrin, J.6
  • 37
    • 79851498829 scopus 로고    scopus 로고
    • Emergence of Klebsiella pneumoniae carbapenemase-producing Proteus mirabilis in Hangzhou, China
    • Sheng ZK, Li JJ, Sheng GP, Sheng JF, Li LJ. Emergence of Klebsiella pneumoniae carbapenemase-producing Proteus mirabilis in Hangzhou, China. Chin Med J (Engl). 2010;123:2568-70.
    • (2010) Chin Med J (Engl). , vol.123 , pp. 2568-2570
    • Sheng, Z.K.1    Li, J.J.2    Sheng, G.P.3    Sheng, J.F.4    Li, L.J.5
  • 38
    • 79955545695 scopus 로고    scopus 로고
    • Transfer of KPC carbapenemase from Klebsiella pneumoniae to Escherichia coli in a patient: First case in Europe
    • Richter SN, Frasson I, Bergo C, Parisi S, Cavallaro A, Palù G. Transfer of KPC carbapenemase from Klebsiella pneumoniae to Escherichia coli in a patient: First case in Europe. J Clin Microbiol. 2011;49:2040-2. http://dx.doi.org/10.1128/JCM.00133-11
    • (2011) J Clin Microbiol. , vol.49 , pp. 2040-2042
    • Richter, S.N.1    Frasson, I.2    Bergo, C.3    Parisi, S.4    Cavallaro, A.5    Palù, G.6
  • 39
    • 84907320739 scopus 로고    scopus 로고
    • Evolución de la resistencia antimicrobiana en bacilos Gram negativos en unidades de cuidados intensivos en Colombia
    • Hernández-Gómez C, Blanco VM, Motoa G, Correa A, Maya JJ, de la Cadena E, et al. Evolución de la resistencia antimicrobiana en bacilos Gram negativos en unidades de cuidados intensivos en Colombia. Biomédica. 2014;34(Supl.1):91-100. http://dx.doi.org/10.7705/biomedica.v34i0.1667
    • (2014) Biomédica , vol.34 , Issue.SUPPL.1 , pp. 91-100
    • Hernández-Gómez, C.1    Blanco, V.M.2    Motoa, G.3    Correa, A.4    Maya, J.J.5    de la Cadena, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.