Ex vivo loading of autologous dendritic cells with tumor antigens

Methods in Molecular Biology

Volumn 1139, Issue , 2014, Pages 41-44

  Rizzo, Manglio M ^a   Alaniz, Laura ^a   Mazzolini, Guillermo ^a  

^a UNIVERSIDAD AUSTRAL   (Argentina)

Author keywords

Autologous tumor tissue; Colon carcinoma; Immunotherapy; Tumor specimen; Tumor associated antigens

Indexed keywords

TUMOR ANTIGEN; TUMOR EXTRACT; AUTOANTIGEN;

ARTICLE; CELL COUNTING; CELL LYSATE; CELL VIABILITY; DENDRITIC CELL; DIGESTIVE SYSTEM CANCER; EX VIVO STUDY; HUMAN; ADOPTIVE IMMUNOTHERAPY; CULTURE TECHNIQUE; CYTOLOGY; GASTROINTESTINAL TUMOR; IMMUNOLOGY; METHODOLOGY;

ANTIGENS, NEOPLASM; AUTOANTIGENS; CELL CULTURE TECHNIQUES; DENDRITIC CELLS; GASTROINTESTINAL NEOPLASMS; HUMANS; IMMUNOTHERAPY, ADOPTIVE;

EID: 84909620015     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-0345-0_5     Document Type: Article

References (11)

1. Palucka K, Banchereau J (2012) Cancer immunotherapy via dendritic cells. Nat Rev Cancer 12:265-277
2. Schuler G et al (1995) Production and properties of large numbers of dendritic cells from human blood. In: Banchereau J, Schmitt D (eds) Dendritic cells in fundamental and clinical immunology. Springer, New York, USA, pp 43-52
3. Chiang CL et al (2010) Whole tumor antigen vaccines. Semin Immunol 22:132-143
4. Geiger JD (2001) Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression. Cancer Res 61:8513-8519
5. Nestle FO (1998) Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat Med 4:328-332
6. Andersen BM, Ohlfest JR (2012) Increasing the efficacy of tumor cell vaccines by enhancing cross priming. Cancer Lett 325:155-164
7. Heath WR, Carbone FR (2001) Crosspresentation, dendritic cells, tolerance and immunity. Annu Rev Immunol 19:47-64
8. Novellino L et al (2005) A listing of human tumor antigens recognized by T cells: March 2004 update. Cancer Immunol Immunother 54:187-207
9. Bhardwaj N (2001) Processing and presentation of antigens by dendritic cells: implications for vaccines. Trends Mol Med 7:388-394
10. Iwashita Y et al (2003) A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer. Cancer Immunol Immunother 52:155-161
11. Mazzolini G et al (2005) Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas. J Clin Oncol 23:999-1010