Degradation of the cytostatic etoposide in chlorinated water by liquid chromatography coupled to quadrupole-Orbitrap mass spectrometry: Identification and quantification of by-products in real water samples

Science of the Total Environment

Volumn 506-507, Issue , 2015, Pages 36-45

  Negreira, Noelia ^a   López de Alda, Miren ^a   Barceló, Damià ^a,b  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

^b UNIVERSITY OF GIRONA   (Spain)

Author keywords

By products; Chlorination; Cytostatics; Etoposide; Orbitrap mass spectrometer; Water samples

Indexed keywords

BYPRODUCTS; CHEMICAL COMPOUNDS; CHLORINATION; CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; SEWAGE; SPECTROMETERS; SPECTROMETRY;

CHEMICAL DISINFECTANTS; CYTOSTATICS; ETOPOSIDE; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; ON-LINE SOLID PHASE EXTRACTION; ORBITRAP; ORBITRAP MASS SPECTROMETRIES; WATER SAMPLES;

EXTRACTION;

3' O DESMETHYL ETOPOSIDE; CHLORINE; ETOPOSIDE; UNCLASSIFIED DRUG; WATER; DISINFECTANT AGENT; WATER POLLUTANT;

CHLORINATION; DEGRADATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SEWAGE;

ARTICLE; CHLORINATION; CONCENTRATION (PARAMETERS); DRUG DEGRADATION; DRUG STABILITY; ION TRAP MASS SPECTROMETRY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MASS SPECTROMETER; QUANTITATIVE ANALYSIS; SAFETY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WASTE WATER MANAGEMENT; WATER ANALYSIS; WATER CONTAMINATION; WATER SAMPLING; ANALYSIS; CHEMISTRY; HALOGENATION; LIQUID CHROMATOGRAPHY; PROCEDURES; WATER POLLUTANT;

CHROMATOGRAPHY, LIQUID; DISINFECTANTS; ETOPOSIDE; HALOGENATION; SOLID PHASE EXTRACTION; WATER POLLUTANTS, CHEMICAL;

EID: 84909606566     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2014.10.097     Document Type: Article

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