Oral delivery of ACE2/Ang-(1-7) bioencapsulated in plant cells protects against experimental Uveitis and autoimmune uveoretinitis

Molecular Therapy

Volumn 22, Issue 12, 2014, Pages 2069-2082

  Shil, Pollob K ^a   Kwon, Kwang Chul ^b   Zhu, Ping ^a   Verma, Amrisha ^a   Daniell, Henry ^b   Li, Qiuhong ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1A RECEPTOR; ANGIOTENSIN 1B RECEPTOR; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN[1-7]; CHOLERA TOXIN B SUBUNIT; DIPEPTIDYL CARBOXYPEPTIDASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; ANGIOTENSIN I; ANGIOTENSIN I (1-7); PEPTIDE FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CHLOROPLAST; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENCAPSULATION; ENDOTOXIN-INDUCED UVEITIS; EXPERIMENTAL AUTOIMMUNE UVEORETINITIS; GENE EXPRESSION; MOUSE; NONHUMAN; PLANT CELL; RETINA VASCULITIS; UVEORETINITIS; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DISEASE MODEL; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; ORAL DRUG ADMINISTRATION; RETINITIS; TRANSGENIC PLANT; UVEITIS;

MUS;

ADMINISTRATION, ORAL; ANGIOTENSIN I; ANIMALS; CHLOROPLASTS; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; PLANTS, GENETICALLY MODIFIED; RETINAL VASCULITIS; RETINITIS; UVEITIS;

EID: 84908696704     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.179     Document Type: Article

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