A systematic review of the clinical relevance of repetitive transcranial magnetic stimulation

Acta Psychiatrica Scandinavica

Volumn 130, Issue 5, 2014, Pages 326-341

  Lepping, P ^a,b   Schonfeldt Lecuona C ^c   Sambhi, R S ^a   Lanka, S V N ^a   Lane, S ^d   Whittington, R ^d   Leucht, S ^e,f,g   Poole, R ^a,b  

^a BETSI CADWALADR UNIVERSITY HEALTH BOARD   (United Kingdom)

^b BANGOR UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF ULM   (Germany)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Clinical relevance; Depression; Repetitive transcranial magnetic stimulation; Systematic review; Treatment resistant depression

Indexed keywords

ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL GLOBAL IMPRESSION SCALE; DEPRESSION; HAMILTON DEPRESSION RATING SCALE; HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION; SYSTEMATIC REVIEW; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME; TREATMENT RESISTANT DEPRESSION; DEPRESSIVE DISORDER; DEPRESSIVE DISORDER, TREATMENT-RESISTANT; PROCEDURES; PSYCHOLOGICAL RATING SCALE; STATISTICS AND NUMERICAL DATA;

DEPRESSIVE DISORDER; DEPRESSIVE DISORDER, TREATMENT-RESISTANT; HUMANS; PSYCHIATRIC STATUS RATING SCALES; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME;

EID: 84908664817     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12276     Document Type: Article

References (102)

1. Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL. Global burden of disease and risk factors. New York, NY: Oxford University Press, 2006.
2. Murray CJ, Lopez AD. The Global Burden of Disease: a comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. Cambridge, MA: Harvard School of Public Health; 1996.
3. Barker AT, Jalinous R, Freeston IL. Non-invasive magnetic stimulation of human motor cortex [letter]. Lancet 1985;1:1106-1107.
4. Drevets WC. Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders. Curr Opin Neurobiol 2001;11:240-249.
5. Drevets WC, Videen TO, Price JL, Preskorn SH, Carmichael ST, Raichle ME. A functional anatomical study of unipolar depression. J Neurosci 1992;12:3628-3641.
6. Leppanen JM. Emotional information processing in mood disorders: a review of behavioral and neuroimaging findings. Curr Opin Psychiatry 2006;19:34-39.
7. Soares JC, Mann JJ. The functional neuroanatomy of mood disorders. J Psychiatr Res 1997;31:393-432.
8. Fales CL, Barch DM, Rundle MM et al. Antidepressant treatment normalizes hypoactivity in dorsolateral prefrontal cortex during emotional interference processing in major depression. J Affect Disord 2009;112:206-211.
9. Grimm S, Beck J, Schuepbach D et al. Imbalance between left and right dorsolateral prefrontal cortex in major depression is linked to negative emotional judgment: an fMRI study in severe major depressive disorder. Biol Psychiatry 2008;63:369-376.
10. Vasic N, Walter H, Hose A, Wolf RC. Gray matter reduction associated with psychopathology and cognitive dysfunction in unipolar depression: a voxel-based morphometry study. J Affect Disord 2008;109:107-116.
11. George MS, Wassermann EM, Williams WA et al. Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. NeuroReport 1995;6:1853-1856.
12. Pascual-Leone A, Rubio B, Pallardo F, Catala MD. Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression. Lancet 1996;348:233-237.
13. Wassermann EM, Grafman J, Berry C et al. Use and safety of a new repetitive transcranial magnetic stimulator. Electroencephalogr Clin Neurophysiol 1996;101:412-417.
14. Siebner HR, Lang N, Rizzo V et al. Preconditioning of low-frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex. J Neurosci 2004;24:3379-3385.
15. Höflich G, Kasper S, Hufnagel A, Ruhrmann S, Möller HJ. Application of transcranial magnetic stimulation in treatment of drug-resistant major depression. Hum Psychopharmacol 1993;8:361-365.
16. Ridding MC, Rothwell JC. Is there a future for therapeutic use of transcranial magnetic stimulation? Nat Rev Neurosci 2007;8:559-567.
17. Herrmann LL, Ebmeier KP. Factors modifying the efficacy of transcranial magnetic stimulation in the treatment of depression: a review. J Clin Psychiatry 2006;67:1870-1876.
18. Ebmeier KP, Herrmann LL. TMS-the beginning of the end or the end of the beginning? Psychol Med 2008;38:319-321.
19. Schutter DJ. Antidepressant efficacy of high-frequency transcranial magnetic stimulation over the left dorsolateral prefrontal cortex in double-blind sham-controlled designs: a meta-analysis. Psychol Med 2009;39:65-75.
20. Slotema CW, Blom JD, Hoek HW, Sommer IE. Should we expand the toolbox of psychiatric treatment methods to include Repetitive Transcranial Magnetic Stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders. J Clin Psychiatry 2010;71:873-884.
21. Berlim MT, van den Eynde F, Tovar-Perdomo S, Daskalakis ZJ. Response, remission and drop-out rates following high-frequency repetitive transcranial magnetic stimulation (rTMS) for treating major depression: a systematic review and meta-analysis of randomized, double-blind and sham-controlled trials. Psychol Med 2014;44:225-239.
22. Leucht S, Fannema H, Engel R, Kasper S, Lepping P, Szegedi A. What does the HAM-D mean? J Affect Disord 2013;148:243-248.
23. Leucht S, Engel RR, Davis JM et al. Equipercentile linking of the Brief Psychiatric Rating Scale and the Clinical Global Impression Scale in a catchment area. Eur Neuropsychopharmacol 2012;22:501-505.
24. Furukawa TA, Akechi T, Azuma H, Okuyama T, Higuchi T. Evidence-based guidelines for interpretation of the Hamilton Rating Scale for Depression. J Clin Psychopharmacol 2007;27:531-534.
25. Lepping P, Sambhi RS, Whittington R, Lane S, Poole R. Clinical relevance of findings in trials of antipsychotics: systematic review. Br J Psychiatry 2011;198:341-345.
26. Leucht S, Cipriani A, Spineli L et al. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet 2013;382:951-962.
27. Abraham G, Milev R, Lazowski L, Jokic R, du Toit R, Lowe A. Repetitive transcranial magnetic stimulation for treatment of elderly patients with depression - an open label trial. Neuropsychiatr Dis Treat 2007;3:919-924.
28. Avery DH, Holtzheimer PE 3rd, Fawaz W et al. A controlled study of repetitive transcranial magnetic stimulation in medication-resistant major depression. Biol Psychiatry 2006;59:187-194.
29. Avery DH, Isenberg KE, Sampson SM et al. Transcranial magnetic stimulation in the acute treatment of major depressive disorder: clinical response in an open-label extension trial. J Clin Psychiatry 2008;69:441-451.
30. Bajbouj M, Brakemeier EL, Schubert F et al. Repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex and cortical excitability in patients with major depressive disorder. Exp Neurol 2005;196:332-338.
31. Bakim B, Uzun UE, Karamustafalioglu O et al. The Combination of Antidepressant Drug Therapy and High-Frequency Repetitive Transcranial Magnetic Stimulation in Medication-Resistant Depression. Klinik Psikofarmakoloji Bülteni 2012;22:244-253.
32. Benadhira R, Saba G, Samaan A et al. Transcranial magnetic stimulation for refractory depression. Am J Psychiatry 2005;162:193.
33. Berlim MT, McGirr A, Beaulieu MM, Turecki G. High frequency repetitive transcranial magnetic stimulation as an augmenting strategy in severe treatment-resistant major depression: a prospective 4-week naturalistic trial. J Affect Disord 2011;130:312-317.
34. Bretlau LG, Lunde M, Lindberg L, Unden M, Dissing S, Bech P. Repetitive transcranial magnetic stimulation (rTMS) in combination with escitalopram in patients with treatment-resistant major depression: a double-blind, randomised, sham-controlled trial. Pharmacopsychiatry 2008;41:41-47.
35. Chen SJ, Chang CH, Tsai HC, Chen ST, Lin C. Superior antidepressant effect occurring 1 month after rTMS: add-on rTMS for subjects with medication-resistant depression. Neuropsychiatr Dis Treat 2013;9:397-401.
36. Conca A, di Pauli J, Beraus W et al. Combining high and low frequencies in rTMS antidepressive treatment: preliminary results. Hum Psychopharmacol 2002;17:353-356.
37. Crevits L, van den Abbeele D, Audenaert K, Goethals M, Dierick M. Effect of repetitive transcranial magnetic stimulation on saccades in depression: a pilot study. Psychiatry Res 2005;135:113-119.
38. Dannon PN, Dolberg OT, Schreiber S, Grunhaus L. Three and six-month outcome following courses of either ECT or rTMS in a population of severely depressed individuals-preliminary report. Biol Psychiatry 2002;51:687-690.
39. Dolberg OT, Dannon PN, Schreiber S, Grunhaus L. Transcranial magnetic stimulation in patients with bipolar depression: a double blind, controlled study. Bipolar Disord 2002;4(Suppl 1):94-95.
40. Fitzgerald PB, Benitez J, de Castella A, Daskalakis ZJ, Brown TL, Kulkarni J. A randomized, controlled trial of sequential bilateral repetitive transcranial magnetic stimulation for treatment-resistant depression. Am J Psychiatry 2006;163:88-94.
41. Fitzgerald PB, Hoy K, Daskalakis ZJ, Kulkarni J. A randomized trial of the anti-depressant effects of low- and high-frequency transcranial magnetic stimulation in treatment-resistant depression. Depress Anxiety 2009;26:229-234.
42. Fitzgerald PB, Hoy KE, Singh A et al. Equivalent beneficial effects of unilateral and bilateral prefrontal cortex transcranial magnetic stimulation in a large randomized trial in treatment-resistant major depression. Int J Neuropsychopharmacol 2013;16:1975-1984.
43. Fitzgerald P, Hoy K, Gunewardene R et al. A randomized trial of unilateral and bilateral prefrontal cortex transcranial magnetic stimulation in treatment-resistant major depression. Psychol Med 2011;41:1187-1196.
44. Fujita K, Koga Y. Clinical application of single-pulse transcranial magnetic stimulation for the treatment of depression. Psychiatry Clin Neurosci 2005;59:425-432.
45. Galletly C, Gill S, Clarke P, Burton C, Fitzgerald PB. A randomized trial comparing repetitive transcranial magnetic stimulation given 3 days/week and 5 days/week for the treatment of major depression: is efficacy related to the duration of treatment or the number of treatments? Psychol Med 2012;42:981-988.
46. Garcia-Toro M, Mayol A, Arnillas H et al. Modest adjunctive benefit with transcranial magnetic stimulation in medication-resistant depression. J Affect Disord 2001;64:271-275.
47. Garcia-Toro M, Salva J, Daumal J et al. High (20-Hz) and low (1-Hz) frequency transcranial magnetic stimulation as adjuvant treatment in medication-resistant depression. Psychiatry Res 2006;146:53-57.
48. George MS, Wassermann EM, Kimbrell TA et al. Mood improvement following daily left prefrontal repetitive transcranial magnetic stimulation in patients with depression: a placebo-controlled crossover trial. Am J Psychiatry 1997;154:1752-1756.
49. George MS, Nahas Z, Molloy M et al. A controlled trial of daily left prefrontal cortex TMS for treating depression. Biol Psychiatry 2000;48:962-970.
50. George MS, Lisanby SH, Avery D et al. Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial. Arch Gen Psychiatry 2010;67:507-516.
51. Grunhaus L, Schreiber S, Dolberg OT, Polak D, Dannon PN. A randomized controlled comparison of electroconvulsive therapy and repetitive transcranial magnetic stimulation in severe and resistant nonpsychotic major depression. Biol Psychiatry 2003;53:324-331.
52. Hansen PE, Videbech P, Clemmensen K, Sturlason R, Jensen HM, Vestergaard P. Repetitive transcranial magnetic stimulation as add-on antidepressant treatment. The applicability of the method in a clinical setting. Nord J Psychiatry 2004;58:455-457.
53. Hausmann A, Kemmler G, Walpoth M et al. No benefit derived from repetitive transcranial magnetic stimulation in depression: a prospective, single centre, randomised, double blind, sham controlled "add on" trial. J Neurol Neurosurg Psychiatry 2004;75:320-322.
54. Hernandez-Ribas R, Deus J, Pujol J et al. Identifying brain imaging correlates of clinical response to repetitive transcranial magnetic stimulation (rTMS) in major depression. Brain Stimul 2013;6:54-61.
55. Herwig U, Lampe Y, Juengling FD et al. Add-on rTMS for treatment of depression: a pilot study using stereotaxic coil-navigation according to PET data. J Psychiatr Res 2003;37:267-275.
56. Herwig U, Fallgatter AJ, Hoppner J et al. Antidepressant effects of augmentative transcranial magnetic stimulation: randomised multicentre trial. Br J Psychiatry 2007;191:441-448.
57. Holtzheimer PE. 3RD, RUSSO J, CLAYPOOLE KH, ROY-BYRNE P, AVERY DH. Shorter duration of depressive episode may predict response to repetitive transcranial magnetic stimulation. Depress Anxiety 2004;19:24-30.
58. Janicak PG, Dowd SM, Martis B et al. Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: preliminary results of a randomized trial. Biol Psychiatry 2002;51:659-667.
59. Janicak PG, Nahas Z, Lisanby SH et al. Durability of clinical benefit with transcranial magnetic stimulation (TMS) in the treatment of pharmacoresistant major depression: assessment of relapse during a 6-month, multisite, open-label study. Brain Stimul 2010;3:187-199.
60. Januel D, Dumortier G, Verdon CM et al. A double-blind sham controlled study of right prefrontal repetitive transcranial magnetic stimulation (rTMS): therapeutic and cognitive effect in medication free unipolar depression during 4 weeks. Prog Neuropsychopharmacol Biol Psychiatry 2006;30:126-130.
61. Jhanwar VG, Bishnoi RJ, Singh L, Jhanwar MR. Utility of repetitive transcranial magnetic stimulation as an augmenting treatment method in treatment-resistant depression. Indian J Psychiatry 2011;53:145-148.
62. Kauffmann CD, Cheema MA, Miller BE. Slow right prefrontal transcranial magnetic stimulation as a treatment for medication-resistant depression: a double-blind, placebo-controlled study. Depress Anxiety 2004;19:59-62.
63. Keshtkar M, Ghanizadeh A, Firoozabadi A. Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for the treatment of major depressive disorder, a randomized controlled clinical trial. J ECT 2011;27:310-314.
64. Kito S, Fujita K, Koga Y. Regional cerebral blood flow changes after low-frequency transcranial magnetic stimulation of the right dorsolateral prefrontal cortex in treatment-resistant depression. Neuropsychobiology 2008;58:29-36.
65. Kito S, Hasegawa T, Koga Y. Neuroanatomical correlates of therapeutic efficacy of low-frequency right prefrontal transcranial magnetic stimulation in treatment-resistant depression. Psychiatry Clin Neurosci 2011;65:175-182.
66. Klein E, Kreinin I, Chistyakov A et al. Therapeutic efficacy of right prefrontal slow repetitive transcranial magnetic stimulation in major depression: a double-blind controlled study. Arch Gen Psychiatry 1999;56:315-320.
67. Koerselman F, Laman DM, van Duijn H, van Duijn MA, Willems MA. A 3-month, follow-up, randomized, placebo-controlled study of repetitive transcranial magnetic stimulation in depression. J Clin Psychiatry 2004;65:1323-1328.
68. Loo C, McFarquhar T, Walter G. Transcranial magnetic stimulation in adolescent depression. Australas Psychiatry 2006;14:81-85.
69. Maihofner C, Ropohl A, Reulbach U et al. Effects of repetitive transcranial magnetic stimulation in depression: a magnetoencephalographic study. NeuroReport 2005;16:1839-1842.
70. Manes F, Jorge R, Morcuende M, Yamada T, Paradiso S, Robinson RG. A controlled study of repetitive transcranial magnetic stimulation as a treatment of depression in the elderly. Int Psychogeriatr 2001;13:225-231.
71. Paillere Martinot ML, Galinowski A, Ringuenet D et al. Influence of prefrontal target region on the efficacy of repetitive transcranial magnetic stimulation in patients with medication-resistant depression: a [(18)F]-fluorodeoxyglucose PET and MRI study. Int J Neuropsychopharmacol 2010;13:45-59.
72. Ming-Li H, Gu Z, Wang X, Tian X. Effects of repetitive transcranial magnetic stimulation on hypothalamic-pituitary-adrenal axis of patients with depression. J Med Colleges PLA 2009;24:337-345.
73. Moller AL, Hjaltason O, Ivarsson O, Stefansson SB. The effects of repetitive transcranial magnetic stimulation on depressive symptoms and the P(300) event-related potential. Nord J Psychiatry 2006;60:282-285.
74. Mosimann UP, Schmitt W, Greenberg BD et al. Repetitive transcranial magnetic stimulation: a putative add-on treatment for major depression in elderly patients. Psychiatry Res 2004;126:123-133.
75. Myczkowski ML, Dias AM, Luvisotto T et al. Effects of repetitive transcranial magnetic stimulation on clinical, social, and cognitive performance in postpartum depression. Neuropsychiatr Dis Treat 2012;8:491-500.
76. Nahas Z, Teneback CC, Kozel A et al. Brain effects of TMS delivered over prefrontal cortex in depressed adults: role of stimulation frequency and coil-cortex distance. J Neuropsychiatry Clin Neurosci 2001;13:459-470.
77. O'reardon JP, Solvason HB, Janicak PG et al. Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial. Biol Psychiatry 2007;62:1208-1216.
78. Padberg F, Zwanzger P, Thoma H et al. Repetitive transcranial magnetic stimulation (rTMS) in pharmacotherapy-refractory major depression: comparative study of fast, slow and sham rTMS. Psychiatry Res 1999;88:163-171.
79. Padberg F, Schule C, Zwanzger P et al. Relation between responses to repetitive transcranial magnetic stimulation and partial sleep deprivation in major depression. J Psychiatr Res 2002;36:131-135.
80. Price GW, Lee JW, Garvey CA, Gibson N. The use of background EEG activity to determine stimulus timing as a means of improving rTMS efficacy in the treatment of depression: a controlled comparison with standard techniques. Brain Stimul 2010;3:140-152.
81. Rossini D, Lucca A, Zanardi R, Magri L, Smeraldi E. Transcranial magnetic stimulation in treatment-resistant depressed patients: a double-blind, placebo-controlled trial. Psychiatry Res 2005;137:1-10.
82. Rossini D, Lucca A, Magri L et al. A symptom-specific analysis of the effect of high-frequency left or low-frequency right transcranial magnetic stimulation over the dorsolateral prefrontal cortex in major depression. Neuropsychobiology 2010;62:91-97.
83. Stern WM, Tormos JM, Press DZ, Pearlman C, Pascual-Leone A. Antidepressant effects of high and low frequency repetitive transcranial magnetic stimulation to the dorsolateral prefrontal cortex: a double-blind, randomized, placebo-controlled trial. J Neuropsychiatry Clin Neurosci 2007;19:179-186.
84. Su TP, Huang CC, Wei IH. Add-on rTMS for medication-resistant depression: a randomized, double-blind, sham-controlled trial in Chinese patients. J Clin Psychiatry 2005;66:930-937.
85. Triggs WJ, McCoy KJ, Greer R et al. Effects of left frontal transcranial magnetic stimulation on depressed mood, cognition, and corticomotor threshold. Biol Psychiatry 1999;45:1440-1446.
86. Triggs WJ, Ricciuti N, Ward HE et al. Right and left dorsolateral pre-frontal rTMS treatment of refractory depression: a randomized, sham-controlled trial. Psychiatry Res 2010;178:467-474.
87. Turnier-Shea Y, Bruno R, Pridmore S. Daily and spaced treatment with transcranial magnetic stimulation in major depression: a pilot study. Aust N Z J Psychiatry 2006;40:759-763.
88. Wang X-M, Yang D-B, Yu Y-F, Huang H, Zhao Z. A controlled study of the repetitive transcranial magnetic stimulation in patients with major depression. Chin J Clin Rehabil 2004;8:9-28.
89. Zheng H, Zhang L, Li L et al. High-frequency rTMS treatment increases left prefrontal myo-inositol in young patients with treatment-resistant depression. Prog Neuropsychopharmacol Biol Psychiatry 2010;34:1189-1195.
90. McNamara B, Ray JL, Arthurs OJ, Boniface S. Transcranial magnetic stimulation for depression and other psychiatric disorders. Psychol Med 2001;31:1141-1146.
91. Burt T, Lisanby SH, Sackeim HA. Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis. Int J Neuropsychopharmacol 2002;5:73-103.
92. Couturier JL. Efficacy of rapid-rate repetitive transcranial magnetic stimulation in the treatment of depression: a systematic review and meta-analysis. J Psychiatry Neurosci 2005;30:83-90.
93. Lam RW, Chan P, Wilkins-Ho M, Yatham LN. Repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and metaanalysis. Can J Psychiatry 2008;53:621-631.
94. Fitzgerald PB, Brown TL, Daskalakis ZJ. The application of transcranial magnetic stimulation in psychiatry and neurosciences research. Acta Psychiatr Scand 2002;105:324-340.
95. Cuijpers P, Smit F, Bohlmeijer E, Hollon SD, Andersson G. Efficacy of cognitive-behavioural therapy and other psychological treatments for adult depression: meta-analytic study of publication bias. Br J Psychiatry 2010;196:173-178.
96. Cuijpers P, Turner EH, Mohr DC et al. Comparison of psychotherapies for adult depression to pill placebo control groups: a meta-analysis. Psychol Med 2014;44:685-695.
97. Waheed W, Whittington R, Sambhi RS et al. A systematic review of the clinical relevance of findings in trials of CBT for depression. Br J Psychiatry 2014 [in press].
98. Fountoulakis KN, Moller HJ. Efficacy of antidepressants: a re-analysis and re-interpretation of the Kirsch data. Int J Neuropsychopharmacol 2011;14:405-412.
99. Melander H, Salmonson T, Abadie E, Van Zwieten-Boot B. A regulatory Apologia-a review of placebo-controlled studies in regulatory submissions of new-generation antidepressants. Eur Neuropsychopharmacol 2008;18:623-627.
100. ECT Review GROUP U. Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis. Lancet 2003;361:799-808.
101. Leucht S, Kane JM, Kissling W, Hamann J, Etschel E, Engel R. Clinical implications of Brief Psychiatric Rating Scale scores. Br J Psychiatry 2005;187:366-371.
102. Guyatt GH, Juniper EF, Walter SD, Griffith LE, Goldstein RS. Interpreting treatment effects in randomised trials. BMJ 1998;316:690-693.