Cellular thrust and parry in the leukemic niche

Blood

Volumn 124, Issue 18, 2014, Pages 2760-2761

  Kfoury, Youmna ^a,b   Scadden, David T ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; EPIDERMAL GROWTH FACTOR; JANUS KINASE 2; LACTIC ACID; VASCULOTROPIN;

ACUTE GRANULOCYTIC LEUKEMIA; ANGIOGENESIS; BREAST TUMOR; CANCER CELL; CANCER GROWTH; CELL GROWTH; CELL TYPE; COLON TUMOR; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; LEUKEMIA; LEUKEMIA CELL; LUNG TUMOR; MACROPHAGE; MESENCHYMAL STROMA CELL; MESENCHYME CELL; MYELODYSPLASTIC SYNDROME; MYELOPROLIFERATIVE NEOPLASM; NONHUMAN; NOTE; OSTEOBLAST; STEM CELL NICHE; STROMA; ANIMAL; DISEASE COURSE; PATHOLOGY;

ANIMALS; DISEASE PROGRESSION; HUMANS; LEUKEMIA; OSTEOBLASTS;

EID: 84908611195     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-09-597716     Document Type: Note

References (9)

1. Krevvata M, Silva BC, Manavalan JS, et al. Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts. Blood. 2014;124(18):2834-2846.
2. Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nat Med. 2013;19(11): 1423-1437.
3. Noy R, Pollard JW. Tumor-associated macrophages: from mechanisms to therapy. Immunity. 2014;41(1):49-61.
4. Colegio OR, Chu NQ, Szabo AL, et al. Functional polarization of tumour-associated macrophages by tumourderived lactic acid [published online ahead of print July 13, 2014]. Nature. doi:10.1038/nature13490.
5. Schepers K, Pietras EM, Reynaud D, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell. 2013;13(3):285-299.
6. Frisch BJ, Ashton JM, Xing L, Becker MW, Jordan CT, Calvi LM. Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia. Blood. 2012;119(2):540-550.
7. Arranz L, Sánchez-Aguilera A, Marti'n-Péez D, et al. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms. Nature. 2014;512(7512): 78-81.
8. Hanoun M, Zhang D, Mizoguchi T, et al. Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche. Cell Stem Cell. 2014;15(3): 365-375.
9. Krause DS, Fulzele K, Catic A, et al. Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nat Med. 2013;19(11): 1513-1517.