Repeated daily dosing with sildenafil provides sustained protection from endothelial dysfunction caused by ischemia and reperfusion: a human in vivo study.

American journal of physiology. Heart and circulatory physiology

Volumn 307, Issue 6, 2014, Pages

  McLaughlin, Kelsey ^a   Lytvyn, Yuliya ^a   Luca, Mary Clare ^a   Liuni, Andrew ^a   Gori, Tommaso ^a   Parker, John D ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GLYCERYL TRINITRATE; MYOGLOBIN; PADGEM PROTEIN; PEROXIDASE; PIPERAZINE DERIVATIVE; PURINE DERIVATIVE; SELP PROTEIN, HUMAN; SILDENAFIL; SULFONE; VASODILATOR AGENT;

ADOLESCENT; ADULT; ARTICLE; BLOOD; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ADMINISTRATION; DRUG EFFECT; ENDOTHELIUM; FOREARM; HEMODYNAMICS; HUMAN; INTRADERMAL DRUG ADMINISTRATION; ISCHEMIA; MALE; METABOLISM; NORMAL HUMAN; PATHOPHYSIOLOGY; PHARMACOLOGICAL PRECONDITIONING; RADIAL ARTERY; RANDOMIZED CONTROLLED TRIAL; REPERFUSION; REPERFUSION INJURY; TIME; TREATMENT OUTCOME; VASCULAR ENDOTHELIUM; VASCULARIZATION; YOUNG ADULT;

ENDOTHELIUM; ISCHEMIA; PHARMACOLOGICAL PRECONDITIONING; REPERFUSION; SILDENAFIL;

ADMINISTRATION, CUTANEOUS; ADOLESCENT; ADULT; BIOLOGICAL MARKERS; DRUG ADMINISTRATION SCHEDULE; ENDOTHELIUM, VASCULAR; FOREARM; HEALTHY VOLUNTEERS; HEMODYNAMICS; HUMANS; MALE; MYOGLOBIN; NITROGLYCERIN; P-SELECTIN; PEROXIDASE; PIPERAZINES; PURINES; RADIAL ARTERY; REPERFUSION INJURY; SULFONES; TIME FACTORS; TREATMENT OUTCOME; VASODILATOR AGENTS; YOUNG ADULT;

EID: 84908511974     PISSN: None     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00215.2014     Document Type: Article

References (0)