Silencing bruton’s tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 307, Issue 6, 2014, Pages L435-L448

  Krupa, Agnieszka ^a,b   Fol, Marek ^a,e   Rahman, Moshiur ^a   Stokes, Karen Y ^c   Florence, Jon M ^a   Leskov, Igor L ^c   Khoretonenko, Mikhail V ^c   Matthay, Michael A ^d   Liu, Kathleen D ^d   Calfee, Carolyn S ^d   Tvinnereim, Amy ^a   Rosenfield, Gabriel R ^a   Kurdowska, Anna K ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^b INSTITUTE OF MEDICAL BIOLOGY   (Poland)

^c LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF LODZ   (Poland)

Author keywords

ALI; Btk; Immune complex; LPS; Neutrophil

Indexed keywords

BRUTON TYROSINE KINASE; FC RECEPTOR IIA; GRANULOCYTE ANTIBODY; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; AGAMMAGLOBULINAEMIA TYROSINE KINASE; FC RECEPTOR; FCGR2A PROTEIN, HUMAN; PROTEIN TYROSINE KINASE; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ALVEOLAR NEUTROPHIL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONTROLLED STUDY; GENE SILENCING; GENETIC TRANSFECTION; HOMEOSTASIS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; ALI; ANIMAL; BAGG ALBINO MOUSE; BTK; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; ENZYMOLOGY; FEMALE; GENETICS; LUNG ALVEOLUS; MALE; METABOLISM; MULTICENTER STUDY; PATHOLOGY;

ALI; BTK; IMMUNE COMPLEX; LPS; NEUTROPHIL;

ACUTE LUNG INJURY; ANIMALS; ANTIGEN-ANTIBODY COMPLEX; FEMALE; GENE SILENCING; HUMANS; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; NEUTROPHILS; PROTEIN-TYROSINE KINASES; PULMONARY ALVEOLI; RECEPTORS, IGG; TOLL-LIKE RECEPTOR 4;

EID: 84908509703     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00234.2013     Document Type: Article

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