A designed conformational shift to control protein binding specificity

Angewandte Chemie (International ed. in English)

Volumn 53, Issue 39, 2014, Pages 10367-10371

  Michielssens, Servaas ^a   Peters, Jan H enning ^a   Ban, David ^a   Pratihar, Supriya ^a   Seeliger, Daniel ^a   Sharma, Monika ^a   Giller, Karin ^a   Sabo, Thomas M ichael ^a   Becker, Stefan ^a   Lee, Donghan ^a   Griesinger, Christian ^a   de Groot, Bert L ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

molecular dynamics; protein design; protein protein interactions; ubiquitin

Indexed keywords

PROTEIN BINDING; UBIQUITIN;

CHEMISTRY; GENETICS; METABOLISM; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; POINT MUTATION; THERMODYNAMICS;

MOLECULAR DYNAMICS SIMULATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POINT MUTATION; PROTEIN BINDING; THERMODYNAMICS; UBIQUITIN;

EID: 84908502680     PISSN: None     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201403102     Document Type: Article

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