-
1
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974, 77:71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
2
-
-
38449089873
-
Genetic mapping and manipulation: Chapter 1-Introduction and basics
-
February 17, WormBook, WormBook (Ed.)
-
Fay D. Genetic mapping and manipulation: Chapter 1-Introduction and basics. The C. elegans Research Community February 17 2006, WormBook, (http://www.wormbook.org). 10.1895/wormbook.1.90.1. WormBook (Ed.).
-
(2006)
The C. elegans Research Community
-
-
Fay, D.1
-
3
-
-
33644750381
-
SMK-1, an essential regulator of DAF-16-mediated longevity
-
Wolff S., Ma H., Burch D., Maciel G.A., Hunter T., Dillin A. SMK-1, an essential regulator of DAF-16-mediated longevity. Cell 2006, 124:1039-1053.
-
(2006)
Cell
, vol.124
, pp. 1039-1053
-
-
Wolff, S.1
Ma, H.2
Burch, D.3
Maciel, G.A.4
Hunter, T.5
Dillin, A.6
-
4
-
-
84884686553
-
Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease
-
Gidalevitz T., Wang N., Deravaj T., Alexander-Floyd J., Morimoto R.I. Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease. BMC Biol. 2013, 11:100.
-
(2013)
BMC Biol.
, vol.11
, pp. 100
-
-
Gidalevitz, T.1
Wang, N.2
Deravaj, T.3
Alexander-Floyd, J.4
Morimoto, R.I.5
-
5
-
-
84908527545
-
Elegans II C.
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor (NY), D.L. Riddle, T. Blumenthal, B.J. Meyer (Eds.)
-
C. elegans II. Section I, The Biological Model 1997, Cold Spring Harbor Laboratory Press, Cold Spring Harbor (NY). 2nd edition. D.L. Riddle, T. Blumenthal, B.J. Meyer (Eds.).
-
(1997)
Section I, The Biological Model
-
-
-
7
-
-
0032509302
-
The C. elegans sequencing consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology
-
The C. elegans sequencing consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 1998, 282:2012-2018.
-
(1998)
Science
, vol.282
, pp. 2012-2018
-
-
-
8
-
-
0037147103
-
Rates of behavior and aging specified by mitochondrial function during development
-
Dillin A., Hsu A.L., Arantes-Oliveira N., Lehrer-Graiwer J., Hsin H., Fraser A.G., Kamath R.S., Ahringer J., Kenyon C. Rates of behavior and aging specified by mitochondrial function during development. Science 2002, 298:2398-2401.
-
(2002)
Science
, vol.298
, pp. 2398-2401
-
-
Dillin, A.1
Hsu, A.L.2
Arantes-Oliveira, N.3
Lehrer-Graiwer, J.4
Hsin, H.5
Fraser, A.G.6
Kamath, R.S.7
Ahringer, J.8
Kenyon, C.9
-
9
-
-
0037466652
-
DAF-16 target genes that control C. elegans life-span and metabolism
-
Lee S.S., Kennedy S., Tolonen A.C., Ruvkun G. DAF-16 target genes that control C. elegans life-span and metabolism. Science 2003, 300:644-647.
-
(2003)
Science
, vol.300
, pp. 644-647
-
-
Lee, S.S.1
Kennedy, S.2
Tolonen, A.C.3
Ruvkun, G.4
-
10
-
-
34447636066
-
Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan
-
Kim Y., Sun H. Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan. Aging Cell 2007, 6:489-503.
-
(2007)
Aging Cell
, vol.6
, pp. 489-503
-
-
Kim, Y.1
Sun, H.2
-
11
-
-
22344443522
-
A systematic RNAi screen for longevity genes in C. elegans
-
Hamilton B., Dong Y., Shindo M., Liu W., Odell I., Ruvkun G., Lee S.S. A systematic RNAi screen for longevity genes in C. elegans. Genes Dev. 2005, 19:1544-1555.
-
(2005)
Genes Dev.
, vol.19
, pp. 1544-1555
-
-
Hamilton, B.1
Dong, Y.2
Shindo, M.3
Liu, W.4
Odell, I.5
Ruvkun, G.6
Lee, S.S.7
-
12
-
-
0035422776
-
Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy
-
Zipperlen P., Fraser A.G., Kamath R.S., Martinez-Campos M., Ahringer J. Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy. EMBO J. 2001, 20:3984-3992.
-
(2001)
EMBO J.
, vol.20
, pp. 3984-3992
-
-
Zipperlen, P.1
Fraser, A.G.2
Kamath, R.S.3
Martinez-Campos, M.4
Ahringer, J.5
-
13
-
-
0141503432
-
Whole-genome analysis of 60 G protein-coupled receptors in Caenorhabditis elegans by gene knockout with RNAi
-
Keating C.D., Kriek N., Daniels M., Ashcroft N.R., Hopper N.A., Siney E.J., Holden-Dye L., Burke J.F. Whole-genome analysis of 60 G protein-coupled receptors in Caenorhabditis elegans by gene knockout with RNAi. Curr. Biol. 2003, 13:1715-1720.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1715-1720
-
-
Keating, C.D.1
Kriek, N.2
Daniels, M.3
Ashcroft, N.R.4
Hopper, N.A.5
Siney, E.J.6
Holden-Dye, L.7
Burke, J.F.8
-
14
-
-
0034029917
-
Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics
-
Lai C.H., Chou C.Y., Chang L.Y., Liu C.S., Lin W. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. Genome Res. 2000, 10:703-713.
-
(2000)
Genome Res.
, vol.10
, pp. 703-713
-
-
Lai, C.H.1
Chou, C.Y.2
Chang, L.Y.3
Liu, C.S.4
Lin, W.5
-
15
-
-
79957467830
-
OrthoList: a compendium of C. elegans genes with human orthologs
-
Shaye D.D., Greenwald I. OrthoList: a compendium of C. elegans genes with human orthologs. PLoS ONE 2011, 6(5):e20085.
-
(2011)
PLoS ONE
, vol.6
, Issue.5
, pp. e20085
-
-
Shaye, D.D.1
Greenwald, I.2
-
16
-
-
0036254584
-
The art and design of genetic screens: Caenorhabditis elegans
-
Jorgensen, Mango The art and design of genetic screens: Caenorhabditis elegans. Nat. Rev. Genet. 2002, 3(5):356-369.
-
(2002)
Nat. Rev. Genet.
, vol.3
, Issue.5
, pp. 356-369
-
-
Jorgensen1
Mango2
-
17
-
-
25444502402
-
Rapid single nucleotide polymorphism mapping in C. elegans
-
Davis, et al. rapid single nucleotide polymorphism mapping in C. elegans. BMC Genomics 2005, 6:118.
-
(2005)
BMC Genomics
, vol.6
, pp. 118
-
-
Davis1
-
18
-
-
53249091939
-
Caenorhabditis elegans mutant allele identification by whole-genome sequencing
-
Sarin, et al. Caenorhabditis elegans mutant allele identification by whole-genome sequencing. Nat. Methods 2008, 5(10):865.
-
(2008)
Nat. Methods
, vol.5
, Issue.10
, pp. 865
-
-
Sarin1
-
19
-
-
58149200962
-
Comparing platforms for C. elegans mutant identification using high-throughput whole-genome sequencing
-
Shen, et al. Comparing platforms for C. elegans mutant identification using high-throughput whole-genome sequencing. PLoS ONE 2008, 3(12):e4012.
-
(2008)
PLoS ONE
, vol.3
, Issue.12
, pp. e4012
-
-
Shen1
-
20
-
-
68349104949
-
A software, MAQGene, facilitating C. elegans whole genome sequence analysis for mutant identification
-
Bigelow, et al. A software, MAQGene, facilitating C. elegans whole genome sequence analysis for mutant identification. Nat. Methods 2009, 6(8):549.
-
(2009)
Nat. Methods
, vol.6
, Issue.8
, pp. 549
-
-
Bigelow1
-
21
-
-
0035826271
-
Increased dosage of sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum, Guarente increased dosage of sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001, 410(6825):227-230.
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum1
Guarente2
-
22
-
-
80053168829
-
Absence of effects of Sir-2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett, et al. Absence of effects of Sir-2 overexpression on lifespan in C. elegans and Drosophila. Nature 2011, 477(7365):482-485.
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. 482-485
-
-
Burnett1
-
23
-
-
80053134340
-
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
-
Viswanathan, Guarente Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes. Nature 2011, 477(7365):E1-E2.
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. E1-E2
-
-
Viswanathan1
Guarente2
-
24
-
-
0032509484
-
Neurobiology of the Caenorhabditis elegans genome
-
Bargmann Neurobiology of the Caenorhabditis elegans genome. Science 1998, 282:2028-2033.
-
(1998)
Science
, vol.282
, pp. 2028-2033
-
-
Bargmann1
-
25
-
-
16044370232
-
2+ channel gene CACNL1A4
-
2+ channel gene CACNL1A4. Cell 1996, 87:543-552.
-
(1996)
Cell
, vol.87
, pp. 543-552
-
-
Ophoff1
-
26
-
-
0024446955
-
Serotonin metabolism in migraine
-
Ferrari, et al. Serotonin metabolism in migraine. Neurology 1989, 39:1239-1242.
-
(1989)
Neurology
, vol.39
, pp. 1239-1242
-
-
Ferrari1
-
27
-
-
0037108459
-
Serotonin promotes G(o)-dependent neuronal migration in Caenorhabditis elegans
-
Kindt, et al. Serotonin promotes G(o)-dependent neuronal migration in Caenorhabditis elegans. Curr. Biol. 2002, 12(20):1738-1747.
-
(2002)
Curr. Biol.
, vol.12
, Issue.20
, pp. 1738-1747
-
-
Kindt1
-
28
-
-
0028999395
-
A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans
-
Schafer, Kenyon A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans. Nature 1995, 375(6526):73-78.
-
(1995)
Nature
, vol.375
, Issue.6526
, pp. 73-78
-
-
Schafer1
Kenyon2
-
29
-
-
0347993817
-
The voltage-gated calcium channel UNC-2 is involved in stress-mediated regulation of tryptophan hydroxylase
-
Estevez, et al. The voltage-gated calcium channel UNC-2 is involved in stress-mediated regulation of tryptophan hydroxylase. J. Neurochem. 2004, 88:102-113.
-
(2004)
J. Neurochem.
, vol.88
, pp. 102-113
-
-
Estevez1
-
30
-
-
59149104333
-
Cerebrospinal fluid cytokine levels in migraine, tension-type headache and cervicogenic headache
-
Bo, et al. Cerebrospinal fluid cytokine levels in migraine, tension-type headache and cervicogenic headache. Cephalalgia 2009, 29(3):365-372.
-
(2009)
Cephalalgia
, vol.29
, Issue.3
, pp. 365-372
-
-
Bo1
-
31
-
-
0019531209
-
Abnormal cell lineages in mutants of the nematode Caenorhabditis elegans
-
Sulston, Horvitz Abnormal cell lineages in mutants of the nematode Caenorhabditis elegans. Dev. Biol. 1981, 82(1):41-55.
-
(1981)
Dev. Biol.
, vol.82
, Issue.1
, pp. 41-55
-
-
Sulston1
Horvitz2
-
32
-
-
0035219986
-
Pattern formation during C. elegans vulval induction
-
Wang, Sternberg, et al. Pattern formation during C. elegans vulval induction. Curr. Top. Dev. Biol. 2001, 51:189-220.
-
(2001)
Curr. Top. Dev. Biol.
, vol.51
, pp. 189-220
-
-
Wang, S.1
-
33
-
-
0029585636
-
The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway
-
Beitel, et al. The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes Dev. 1995, 9:3149-3162.
-
(1995)
Genes Dev.
, vol.9
, pp. 3149-3162
-
-
Beitel1
-
34
-
-
0031904310
-
Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP Kinase
-
Jacobs, et al. Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP Kinase. Genetics 1998, 149:1809-1822.
-
(1998)
Genetics
, vol.149
, pp. 1809-1822
-
-
Jacobs1
-
35
-
-
0027422247
-
The pathway to signal achievement
-
Egan, Weinberg The pathway to signal achievement. Nature 1993, 365(6449):781-783.
-
(1993)
Nature
, vol.365
, Issue.6449
, pp. 781-783
-
-
Egan1
Weinberg2
-
36
-
-
50749133543
-
Signal transduction and growth control in normal and cancer cells
-
Pawson, Hunter Signal transduction and growth control in normal and cancer cells. Curr. Opin. Genet. Dev. 1994, 4(1):1-4.
-
(1994)
Curr. Opin. Genet. Dev.
, vol.4
, Issue.1
, pp. 1-4
-
-
Pawson1
Hunter2
-
37
-
-
0002051584
-
The Genome
-
Cold Spring Harbor Laboratory Press, New York, Riddle, Blumenthal, Meyer, Priess (Eds.)
-
Waterston, et al. The Genome. C. elegans II 1997, vol. 33:23-45. Cold Spring Harbor Laboratory Press, New York. Riddle, Blumenthal, Meyer, Priess (Eds.).
-
(1997)
C. elegans II
, vol.33
, pp. 23-45
-
-
Waterston1
-
38
-
-
0032545933
-
Potent and specific genetic interference by double- stranded RNA in Caenorhabditis elegans
-
Fire, et al. Potent and specific genetic interference by double- stranded RNA in Caenorhabditis elegans. Nature 1998, 391(6669):806-811.
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire1
-
39
-
-
0038784432
-
Inducible systemic RNA silencing in Caenorhabditis elegans
-
Timmons, et al. Inducible systemic RNA silencing in Caenorhabditis elegans. Mol. Biol. Cell 2003, 14(7):2972-2983.
-
(2003)
Mol. Biol. Cell
, vol.14
, Issue.7
, pp. 2972-2983
-
-
Timmons1
-
40
-
-
0035941485
-
Ingestion of bacterial expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
-
Timmons, et al. Ingestion of bacterial expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 2001, 263(1-2):103-112.
-
(2001)
Gene
, vol.263
, Issue.1-2
, pp. 103-112
-
-
Timmons1
-
41
-
-
0032538391
-
RNAi in C. elegans: soaking in the genome sequence
-
Tabara, et al. RNAi in C. elegans: soaking in the genome sequence. Science 1998, 282(5388):430-431.
-
(1998)
Science
, vol.282
, Issue.5388
, pp. 430-431
-
-
Tabara1
-
42
-
-
0033968037
-
Heritable and inducible genetics interference by double-stranded RNA encoded by transgenes
-
Tavernakis, et al. Heritable and inducible genetics interference by double-stranded RNA encoded by transgenes. Nat. Genet. 2000, 24(2):180-183.
-
(2000)
Nat. Genet.
, vol.24
, Issue.2
, pp. 180-183
-
-
Tavernakis1
-
43
-
-
0037192490
-
Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1
-
Winston, et al. Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science 2002, 295(5564):2456-2459.
-
(2002)
Science
, vol.295
, Issue.5564
, pp. 2456-2459
-
-
Winston1
-
44
-
-
34250646692
-
Systemic RNAi in Caenorhabditis elegans
-
Hunter, et al. Systemic RNAi in Caenorhabditis elegans. Cold Spring Harb. Symp. Quant. Biol. 2006, 71:95-100.
-
(2006)
Cold Spring Harb. Symp. Quant. Biol.
, vol.71
, pp. 95-100
-
-
Hunter1
-
45
-
-
0037031152
-
Loss of putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi
-
Simmer, et al. Loss of putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Curr. Biol. 2002, 12(15):1317-1319.
-
(2002)
Curr. Biol.
, vol.12
, Issue.15
, pp. 1317-1319
-
-
Simmer1
-
46
-
-
1342346710
-
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
-
Kennedy, et al. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature 2004, 427(6975):645-649.
-
(2004)
Nature
, vol.427
, Issue.6975
, pp. 645-649
-
-
Kennedy1
-
47
-
-
77954711627
-
Enhanced neuronal RNAi in C. elegans using SID-1
-
Calixto, et al. Enhanced neuronal RNAi in C. elegans using SID-1. Nat. Methods 2010, 7(7):554-559.
-
(2010)
Nat. Methods
, vol.7
, Issue.7
, pp. 554-559
-
-
Calixto1
-
48
-
-
78650944949
-
The cell-non-autonomous nature of electron transport chain-mediated longevity
-
Durieux, et al. The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell 2011, 144(1):79-91.
-
(2011)
Cell
, vol.144
, Issue.1
, pp. 79-91
-
-
Durieux1
-
49
-
-
0035229245
-
Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
-
(research 0002.1-0002.10)
-
Kamath, et al. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol. 2001, 2(1). (research 0002.1-0002.10).
-
(2001)
Genome Biol.
, vol.2
, Issue.1
-
-
Kamath1
-
50
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath, et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 2003, 421(6920):231-237.
-
(2003)
Nature
, vol.421
, Issue.6920
, pp. 231-237
-
-
Kamath1
-
51
-
-
11844273868
-
RNA interference in Caenorhabditis elegans
-
Wang, Barr RNA interference in Caenorhabditis elegans. Methods Enzymol. 2005, 392:36-55.
-
(2005)
Methods Enzymol.
, vol.392
, pp. 36-55
-
-
Wang1
Barr2
-
52
-
-
7444270371
-
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library
-
Rual, et al. Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res. 2004, 14(10B):2162-2168.
-
(2004)
Genome Res.
, vol.14
, Issue.10 B
, pp. 2162-2168
-
-
Rual1
-
53
-
-
84880059365
-
MRNA on the move: the road to its biological destiny
-
Eliscovich, et al. mRNA on the move: the road to its biological destiny. J. Biol. Chem. 2013, 288(28):20361-20368.
-
(2013)
J. Biol. Chem.
, vol.288
, Issue.28
, pp. 20361-20368
-
-
Eliscovich1
-
54
-
-
84867868500
-
Regulation of eukaryotic gene expression by the untranslated gene regioins and other non-coding elements
-
Barrett, et al. Regulation of eukaryotic gene expression by the untranslated gene regioins and other non-coding elements. Cell. Mol. Life Sci. 2012, 69(21):3613-3634.
-
(2012)
Cell. Mol. Life Sci.
, vol.69
, Issue.21
, pp. 3613-3634
-
-
Barrett1
-
55
-
-
48949116724
-
Studying gene function in Caenorhabditis elegans using RNA-mediated interference
-
Maine Studying gene function in Caenorhabditis elegans using RNA-mediated interference. Brief. Funct. Genomic Proteomic 2008, 7(3):184-194.
-
(2008)
Brief. Funct. Genomic Proteomic
, vol.7
, Issue.3
, pp. 184-194
-
-
Maine1
-
56
-
-
77952239526
-
Coditional gene expression and RNAi using MEC-8-dependent splicing in C.elegans
-
Calixto, et al. Coditional gene expression and RNAi using MEC-8-dependent splicing in C.elegans. Nat. Methods 2010, 7(5):407-411.
-
(2010)
Nat. Methods
, vol.7
, Issue.5
, pp. 407-411
-
-
Calixto1
-
57
-
-
0036742509
-
A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline
-
Colaiácovo, et al. A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline. Genetics 2002, 162(1):113-128.
-
(2002)
Genetics
, vol.162
, Issue.1
, pp. 113-128
-
-
Colaiácovo1
-
58
-
-
0033639116
-
A global profile of germline gene expression in C. elegans
-
Reinke, et al. A global profile of germline gene expression in C. elegans. Mol. Cell 2000, 6:605-616.
-
(2000)
Mol. Cell
, vol.6
, pp. 605-616
-
-
Reinke1
-
59
-
-
41949097891
-
C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging
-
van Ham T.J., Thijssen K.L., Breitling R., Hofstra R.M., Plasterk R.H., Nollen E.A. C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging. PLoS Genet. 2008, 4:e1000027.
-
(2008)
PLoS Genet.
, vol.4
, pp. e1000027
-
-
van Ham, T.J.1
Thijssen, K.L.2
Breitling, R.3
Hofstra, R.M.4
Plasterk, R.H.5
Nollen, E.A.6
-
60
-
-
84866297918
-
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation
-
van der Goot, et al. Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation. Proc. Natl. Acad. Sci. U. S. A. 2012, 109(37):14912-14917.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, Issue.37
, pp. 14912-14917
-
-
van der, Goot1
-
61
-
-
1542298437
-
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions
-
Simmer, et al. Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol. 2003, 1(1):E12.
-
(2003)
PLoS Biol.
, vol.1
, Issue.1
, pp. E12
-
-
Simmer1
-
62
-
-
77953667076
-
Neurodegenerative diseases: lessons from genome-wide screens in small model organisms
-
van Ham T.J., Breitling R., Swertz M.A., Nollen E.A. Neurodegenerative diseases: lessons from genome-wide screens in small model organisms. EMBO Mol. Med. 2009, 1:360-370.
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 360-370
-
-
van Ham, T.J.1
Breitling, R.2
Swertz, M.A.3
Nollen, E.A.4
-
63
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci. 2003, 4:49-60.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
64
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti F., Dobson C.M. Protein misfolding, functional amyloid, and human disease. Annu. Rev. Biochem. 2006, 75:333-366.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
65
-
-
77955881152
-
ANS binding reveals common features of cytotoxic amyloid species
-
Bolognesi B., Kumita J.R., Barros T.P., Esbjorner E.K., Luheshi L.M., Crowther D.C., Wilson M.R., Dobson C.M., Favrin G., Yerbury J.J. ANS binding reveals common features of cytotoxic amyloid species. ACS Chem. Biol. 2010, 20:735-740.
-
(2010)
ACS Chem. Biol.
, vol.20
, pp. 735-740
-
-
Bolognesi, B.1
Kumita, J.R.2
Barros, T.P.3
Esbjorner, E.K.4
Luheshi, L.M.5
Crowther, D.C.6
Wilson, M.R.7
Dobson, C.M.8
Favrin, G.9
Yerbury, J.J.10
-
66
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate M., Mitra S., Schweitzer E.S., Segal M.R., Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 2004, 14:805-810.
-
(2004)
Nature
, vol.14
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
67
-
-
0032432922
-
Mutations in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and suggest a link with cholinergic transmission
-
Bessou C., Giugia J.B., Franks C.J., Holden-Dye L., Ségalat L. Mutations in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and suggest a link with cholinergic transmission. Neurogenetics 1998, 2:61-72.
-
(1998)
Neurogenetics
, vol.2
, pp. 61-72
-
-
Bessou, C.1
Giugia, J.B.2
Franks, C.J.3
Holden-Dye, L.4
Ségalat, L.5
-
68
-
-
0036678146
-
The threshold for polyglutamine expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
-
Morley J.F., Brignull H.R., Weyers J.J., Morimoto R.I. The threshold for polyglutamine expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:10417-10422.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 10417-10422
-
-
Morley, J.F.1
Brignull, H.R.2
Weyers, J.J.3
Morimoto, R.I.4
-
69
-
-
38649084391
-
Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model
-
Hamamichi S., Rivas R.N., Knight A.L., Cao S., Caldwell K.A., Caldwell G.A. Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:728-733.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 728-733
-
-
Hamamichi, S.1
Rivas, R.N.2
Knight, A.L.3
Cao, S.4
Caldwell, K.A.5
Caldwell, G.A.6
-
70
-
-
52949083619
-
A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans
-
Kuwahara T., Koyama A., Koyama S., Yoshina S., Ren C.H., Kato T., Mitani S., Iwatsubo T. A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans. Hum. Mol. Genet. 2008, 17:2997-3009.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 2997-3009
-
-
Kuwahara, T.1
Koyama, A.2
Koyama, S.3
Yoshina, S.4
Ren, C.H.5
Kato, T.6
Mitani, S.7
Iwatsubo, T.8
-
71
-
-
0028981288
-
Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans
-
Link C.D. Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:9368-9372.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 9368-9372
-
-
Link, C.D.1
-
72
-
-
0034691513
-
Presenilin is required for proper morphology and function of neurons in C. elegans
-
Wittenburg N., Eimer S., Lakowski B., Roèhrig S., Rudolph C., Baumeister R. Presenilin is required for proper morphology and function of neurons in C. elegans. Nature 2000, 406:306-309.
-
(2000)
Nature
, vol.406
, pp. 306-309
-
-
Wittenburg, N.1
Eimer, S.2
Lakowski, B.3
Roèhrig, S.4
Rudolph, C.5
Baumeister, R.6
-
73
-
-
33748792821
-
Opposing activities protect against age-onset proteotoxicity
-
Cohen E., Bieschke J., Perciavalle R.M., Kelly J.W., Dillin A. Opposing activities protect against age-onset proteotoxicity. Science 2006, 313:1604-1610.
-
(2006)
Science
, vol.313
, pp. 1604-1610
-
-
Cohen, E.1
Bieschke, J.2
Perciavalle, R.M.3
Kelly, J.W.4
Dillin, A.5
-
74
-
-
71449108913
-
Reduced IGF-1 signaling delays age-associated proteotoxicity in mice
-
Cohen E., Paulsson J.F., Blinder P., Burstyn-Cohen T., Du D., Estepa G., Adame A., Pham H.M., Holzenberger M., Kelly J.W., Masliah E., Dillin A. Reduced IGF-1 signaling delays age-associated proteotoxicity in mice. Cell 2009, 139:1157-1169.
-
(2009)
Cell
, vol.139
, pp. 1157-1169
-
-
Cohen, E.1
Paulsson, J.F.2
Blinder, P.3
Burstyn-Cohen, T.4
Du, D.5
Estepa, G.6
Adame, A.7
Pham, H.M.8
Holzenberger, M.9
Kelly, J.W.10
Masliah, E.11
Dillin, A.12
-
75
-
-
33646133424
-
Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans
-
Kraemer B.C., Burgess J.K., Chen J.H., Thomas J.H., Schellenberg G.D. Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans. Hum. Mol. Genet. 2006, 15:1483-1496.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1483-1496
-
-
Kraemer, B.C.1
Burgess, J.K.2
Chen, J.H.3
Thomas, J.H.4
Schellenberg, G.D.5
-
76
-
-
77955647865
-
Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity
-
van Ham T.J., Holmberg M.A., van der Goot A.T., Teuling E., Garcia-Arencibia M., Kim H.E., Du D., Thijssen K.L., Wiersma M., Burggraaff R., van Bergeijk P., van Rheenen J., van Veluw G.J., Hofstra R.M., Rubinsztein D.C., Nollen E.A. Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity. Cell 2010, 20:601-612.
-
(2010)
Cell
, vol.20
, pp. 601-612
-
-
van Ham, T.J.1
Holmberg, M.A.2
van der Goot, A.T.3
Teuling, E.4
Garcia-Arencibia, M.5
Kim, H.E.6
Du, D.7
Thijssen, K.L.8
Wiersma, M.9
Burggraaff, R.10
van Bergeijk, P.11
van Rheenen, J.12
van Veluw, G.J.13
Hofstra, R.M.14
Rubinsztein, D.C.15
Nollen, E.A.16
-
77
-
-
84857989952
-
Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons
-
Lejeune F.X., Mesrob L., Parmentier F., Bicep C., Vazquez-Manrique R.P., Alex Parker J., Vert J.P., Tourette C., Neri C. Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons. BMC Genomics 2012, 13:91.
-
(2012)
BMC Genomics
, vol.13
, pp. 91
-
-
Lejeune, F.X.1
Mesrob, L.2
Parmentier, F.3
Bicep, C.4
Vazquez-Manrique, R.P.5
Alex Parker, J.6
Vert, J.P.7
Tourette, C.8
Neri, C.9
-
78
-
-
35448938087
-
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
-
Komatsu M., Wang Q.J., Holstein G.R., Friedrich V.L., Iwata J., Kominami E., Chait B.T., Tanaka K., Yue Z. Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:14489-14494.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 14489-14494
-
-
Komatsu, M.1
Wang, Q.J.2
Holstein, G.R.3
Friedrich, V.L.4
Iwata, J.5
Kominami, E.6
Chait, B.T.7
Tanaka, K.8
Yue, Z.9
-
79
-
-
84883541737
-
PolyQ disease: misfiring of a developmental cell death program?
-
Blum E.S., Schwendeman A.R., Shaham S. PolyQ disease: misfiring of a developmental cell death program?. Trends Cell Biol. 2013, 23:168-174.
-
(2013)
Trends Cell Biol.
, vol.23
, pp. 168-174
-
-
Blum, E.S.1
Schwendeman, A.R.2
Shaham, S.3
-
80
-
-
0033524413
-
Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron
-
Faber P.W., Alter J.R., MacDonald M.E., Hart A.C. Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:179-184.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 179-184
-
-
Faber, P.W.1
Alter, J.R.2
MacDonald, M.E.3
Hart, A.C.4
-
81
-
-
0035818590
-
Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death
-
Parker J.A., Connolly J.B., Wellington C., Hayden M., Dausset J., Neri C. Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:13318-13323.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 13318-13323
-
-
Parker, J.A.1
Connolly, J.B.2
Wellington, C.3
Hayden, M.4
Dausset, J.5
Neri, C.6
-
82
-
-
33747053662
-
Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model
-
Brignull H.R., Moore F.E., Tang S.J., Morimoto R.I. Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model. J. Neurosci. 2006, 26:7597-7606.
-
(2006)
J. Neurosci.
, vol.26
, pp. 7597-7606
-
-
Brignull, H.R.1
Moore, F.E.2
Tang, S.J.3
Morimoto, R.I.4
-
83
-
-
2342652188
-
Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation
-
Nollen E.A., Garcia S.M., van Haaften H.G., Kim S., Chavez A., Morimoto R.I., Plasterk R.H. Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:6403-6408.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6403-6408
-
-
Nollen, E.A.1
Garcia, S.M.2
van Haaften, H.G.3
Kim, S.4
Chavez, A.5
Morimoto, R.I.6
Plasterk, R.H.7
-
84
-
-
84855258498
-
A genetic screening strategy identifies novel regulators of the proteostasis network
-
Silva M.C., Fox S., Beam M., Thakkar H., Amaral M.D., Morimoto R.I. A genetic screening strategy identifies novel regulators of the proteostasis network. PLoS Genet. 2011, 7:e1002438.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002438
-
-
Silva, M.C.1
Fox, S.2
Beam, M.3
Thakkar, H.4
Amaral, M.D.5
Morimoto, R.I.6
-
85
-
-
84865722715
-
-
Falsone S.F., Meyer N.H., Schrank E., Leitinger G., Pham C.L., Fodero-Tavoletti M.T., Holmberg M., Dulle M., Scicluna B., Gesslbauer B., Rückert H.M., Wagner G.E., Merle D.A., Nollen E.A., Kungl A.J., Hill A.F., Cappai R., Zangger K. Cell. Reprogram. 2012, 2:358-371.
-
(2012)
Cell. Reprogram.
, vol.2
, pp. 358-371
-
-
Falsone, S.F.1
Meyer, N.H.2
Schrank, E.3
Leitinger, G.4
Pham, C.L.5
Fodero-Tavoletti, M.T.6
Holmberg, M.7
Dulle, M.8
Scicluna, B.9
Gesslbauer, B.10
Rückert, H.M.11
Wagner, G.E.12
Merle, D.A.13
Nollen, E.A.14
Kungl, A.J.15
Hill, A.F.16
Cappai, R.17
Zangger, K.18
-
86
-
-
33745919520
-
Epidemiology of Parkinson's disease
-
de Lau L.M., Breteler M.M. Epidemiology of Parkinson's disease. Lancet Neurol. 2006, 5:525-535.
-
(2006)
Lancet Neurol.
, vol.5
, pp. 525-535
-
-
de Lau, L.M.1
Breteler, M.M.2
-
87
-
-
34347405256
-
Parkinson's disease: genetics and beyond
-
Inamdar N.N., Arulmozhi D.K., Tandon A., Bodhankar S.L. Parkinson's disease: genetics and beyond. Curr. Neuropharmacol. 2007, 5:99-113.
-
(2007)
Curr. Neuropharmacol.
, vol.5
, pp. 99-113
-
-
Inamdar, N.N.1
Arulmozhi, D.K.2
Tandon, A.3
Bodhankar, S.L.4
-
88
-
-
0141741347
-
Parkinson's disease: mechanisms and models
-
Przedborski S., Dauer W. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Przedborski, S.1
Dauer, W.2
-
89
-
-
0034776095
-
Parkin ubiquitinates the α-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease
-
Chung K.K., Zhang Y., Lim K.L., Tanaka Y., Huang H., Gao J., Ross C.A., Dawson V.L., Dawson T.M. Parkin ubiquitinates the α-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat. Med. 2001, 7:1144-1150.
-
(2001)
Nat. Med.
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
Zhang, Y.2
Lim, K.L.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, C.A.7
Dawson, V.L.8
Dawson, T.M.9
-
90
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A., Schmitz Y., Fariñas I., Choi-Lundberg D., Ho W.H., Castillo P.E., Shinsky N., Verdugo J.M., Armanini M., Ryan A., Hynes M., Phillips H., Sulzer D., Rosenthal A. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 2000, 25:239-252.
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Fariñas, I.3
Choi-Lundberg, D.4
Ho, W.H.5
Castillo, P.E.6
Shinsky, N.7
Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
91
-
-
0031763264
-
The synuclein family
-
Lavedan C. The synuclein family. Genome Res. 1998, 8:871-880.
-
(1998)
Genome Res.
, vol.8
, pp. 871-880
-
-
Lavedan, C.1
-
92
-
-
0032102455
-
The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
-
Clayton D.F., George J.M. The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. Trends Neurosci. 1998, 21:249-254.
-
(1998)
Trends Neurosci.
, vol.21
, pp. 249-254
-
-
Clayton, D.F.1
George, J.M.2
-
93
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W.G., Lazzarini A.M., Duvoisin R.C., Di Iorio G., Golbe L.I., Nussbaum R.L. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997, 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
94
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Krüger R., Kuhn W., Müller T., Woitalla D., Graeber M., Kösel S., Przuntek H., Epplen J.T., Schöls L., Riess O. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet. 1998, 18:106-108.
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Krüger, R.1
Kuhn, W.2
Müller, T.3
Woitalla, D.4
Graeber, M.5
Kösel, S.6
Przuntek, H.7
Epplen, J.T.8
Schöls, L.9
Riess, O.10
-
95
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz J.J., Alegre J., Gómez-Esteban J.C., Lezcano E., Ros R., Ampuero I., Vidal L., Hoenicka J., Rodriguez O., Atarés B., Llorens V., Gomez Tortosa E., del Ser T., Muñoz D.G., de Yebenes J.G. The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol. 2004, 55:164-173.
-
(2004)
Ann. Neurol.
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gómez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atarés, B.10
Llorens, V.11
Gomez Tortosa, E.12
del Ser, T.13
Muñoz, D.G.14
de Yebenes, J.G.15
-
96
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin M.C., Kachergus J., Roumier C., Mouroux V., Douay X., Lincoln S., Levecque C., Larvor L., Andrieux J., Hulihan M., Waucquier N., Defebvre L., Amouyel P., Farrer M., Destée A. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 2004, 364:1167-1169.
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destée, A.15
-
97
-
-
0242300619
-
Alpha-synuclein locus triplication causes Parkinson's disease
-
Singleton A.B., Farrer M., Johnson J., Singleton A., Hague S., Kachergus J., Hulihan M., Peuralinna T., Dutra A., Nussbaum R., Lincoln S., Crawley A., Hanson M., Maraganore D., Adler C., Cookson M.R., Muenter M., Baptista M., Miller D., Blancato J., Hardy J., Gwinn-Hardy K. Alpha-synuclein locus triplication causes Parkinson's disease. Science 2003, 302:841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
98
-
-
33749667345
-
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data
-
Fung, et al. Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol. 2006, 5:911-916.
-
(2006)
Lancet Neurol.
, vol.5
, pp. 911-916
-
-
Fung1
-
99
-
-
0037123766
-
Molecular architecture and functional model of the endocytic AP2 complex
-
Collins B.M., McCoy A.J., Kent H.M., Evans P.R., Owen D.J. Molecular architecture and functional model of the endocytic AP2 complex. Cell 2002, 109:523-535.
-
(2002)
Cell
, vol.109
, pp. 523-535
-
-
Collins, B.M.1
McCoy, A.J.2
Kent, H.M.3
Evans, P.R.4
Owen, D.J.5
-
101
-
-
79952747862
-
Alzheimer's disease
-
Ballard C., Gauthier S., Corbett A., Brayne C., Aarsland D., Jones E. Alzheimer's disease. Lancet 2011, 377:1019-1031.
-
(2011)
Lancet
, vol.377
, pp. 1019-1031
-
-
Ballard, C.1
Gauthier, S.2
Corbett, A.3
Brayne, C.4
Aarsland, D.5
Jones, E.6
-
102
-
-
26444463460
-
The H1c haplotype at the MAPT locus is associated with Alzheimer's disease
-
Myers A.J., Kaleem M., Marlowe L., Pittman A.M., Lees A.J., Fung H.C., Duckworth J., Leung D., Gibson A., Morris C.M., de Silva R., Hardy J. The H1c haplotype at the MAPT locus is associated with Alzheimer's disease. Hum. Mol. Genet. 2005, 14:2399-23404.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2399-23404
-
-
Myers, A.J.1
Kaleem, M.2
Marlowe, L.3
Pittman, A.M.4
Lees, A.J.5
Fung, H.C.6
Duckworth, J.7
Leung, D.8
Gibson, A.9
Morris, C.M.10
de Silva, R.11
Hardy, J.12
-
103
-
-
34250335127
-
Functional MAPT haplotypes: bridging the gap between genotype and neuropathology
-
Caffrey T.M., Wade-Martins R. Functional MAPT haplotypes: bridging the gap between genotype and neuropathology. Neurobiol. Dis. 2007, 27:1-10.
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 1-10
-
-
Caffrey, T.M.1
Wade-Martins, R.2
-
104
-
-
69249153430
-
The Caenorhabditis elegans Aß1-42 model of Alzheimer disease predominantly expresses Aß3-42
-
McGoll G., Roberts B.R., Gunn A.P., Perez K.A., Tew D.J., Masters C.L., Barnham K.J., Cherny R.A., Bush A.I. The Caenorhabditis elegans Aß1-42 model of Alzheimer disease predominantly expresses Aß3-42. J. Biol. Chem. 2009, 284:22697-22702.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 22697-22702
-
-
McGoll, G.1
Roberts, B.R.2
Gunn, A.P.3
Perez, K.A.4
Tew, D.J.5
Masters, C.L.6
Barnham, K.J.7
Cherny, R.A.8
Bush, A.I.9
-
105
-
-
0037405291
-
Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model
-
Link C.D., Taft A., Kapulkin V., Duke K., Kim S., Fei Q., Wood D.E., Sahagan B.G. Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model. Neurobiol. Aging 2003, 24:397-413.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 397-413
-
-
Link, C.D.1
Taft, A.2
Kapulkin, V.3
Duke, K.4
Kim, S.5
Fei, Q.6
Wood, D.E.7
Sahagan, B.G.8
-
106
-
-
33845613251
-
Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
-
Wu Y., Wu Z., Butko P., Christen Y., Lambert M.P., Klein W.L., Link C.D., Luo Y. Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J. Neurosci. 2006, 26:13102-13113.
-
(2006)
J. Neurosci.
, vol.26
, pp. 13102-13113
-
-
Wu, Y.1
Wu, Z.2
Butko, P.3
Christen, Y.4
Lambert, M.P.5
Klein, W.L.6
Link, C.D.7
Luo, Y.8
-
107
-
-
84869210360
-
Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease
-
McColl G., Roberts B.R., Pukala T.L., Kenche V.B., Roberts C.M., Link C.D., Ryan T.M., Masters C.L., Barnham K.J., Bush A.I., Cherny R.A. Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease. Mol. Neurodegener. 2012, 7:57.
-
(2012)
Mol. Neurodegener.
, vol.7
, pp. 57
-
-
McColl, G.1
Roberts, B.R.2
Pukala, T.L.3
Kenche, V.B.4
Roberts, C.M.5
Link, C.D.6
Ryan, T.M.7
Masters, C.L.8
Barnham, K.J.9
Bush, A.I.10
Cherny, R.A.11
-
108
-
-
26944463072
-
Progressive neurodegeneration in C. elegans model of tauopathy
-
Miyasaka T., Ding Z., Gengyo-Ando K., Oue M., Yamaguchi H., Mitani S., Ihara Y. Progressive neurodegeneration in C. elegans model of tauopathy. Neurobiol. Dis. 2005, 20:372-383.
-
(2005)
Neurobiol. Dis.
, vol.20
, pp. 372-383
-
-
Miyasaka, T.1
Ding, Z.2
Gengyo-Ando, K.3
Oue, M.4
Yamaguchi, H.5
Mitani, S.6
Ihara, Y.7
-
109
-
-
56049100463
-
A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau
-
Brandt R., Gergou A., Wacker I., Fath T., Hutter H. A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau. Neurobiol. Aging 2009, 30:22-33.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 22-33
-
-
Brandt, R.1
Gergou, A.2
Wacker, I.3
Fath, T.4
Hutter, H.5
-
110
-
-
0042357192
-
Alpha(7) nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation
-
Wang H.Y., Li W.W., Benedetti N.J., Lee D.H.S. Alpha(7) nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation. J. Biol. Chem. 2003, 278:31547-31553.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31547-31553
-
-
Wang, H.Y.1
Li, W.W.2
Benedetti, N.J.3
Lee, D.H.S.4
-
111
-
-
33745223646
-
Finding function in novel targets: C. elegans as a model organism
-
Kaletta T., Hengartner M.O. Finding function in novel targets: C. elegans as a model organism. Nat. Rev. Drug Discov. 2006, 5:387-398.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 387-398
-
-
Kaletta, T.1
Hengartner, M.O.2
-
112
-
-
82755197062
-
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast
-
Treusch S., Hamamichi S., Goodman J.L., Matlack K.E., Chung C.Y., Baru V., Shulman J.M., Parrado A., Bevis B.J., Valastyan J.S., Han H., Lindhagen-Persson M., Reiman E.M., Evans D.A., Bennett D.A., Olofsson A., DeJager P.L., Tanzi R.E., Caldwell K.A., Caldwell G.A., Lindquist S. Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science 2011, 334:1241-1245.
-
(2011)
Science
, vol.334
, pp. 1241-1245
-
-
Treusch, S.1
Hamamichi, S.2
Goodman, J.L.3
Matlack, K.E.4
Chung, C.Y.5
Baru, V.6
Shulman, J.M.7
Parrado, A.8
Bevis, B.J.9
Valastyan, J.S.10
Han, H.11
Lindhagen-Persson, M.12
Reiman, E.M.13
Evans, D.A.14
Bennett, D.A.15
Olofsson, A.16
DeJager, P.L.17
Tanzi, R.E.18
Caldwell, K.A.19
Caldwell, G.A.20
Lindquist, S.21
more..
-
113
-
-
79851507672
-
Functional screening of Alzheimer pathology genome-wide association signals in Drosophila
-
Shulman J.M., Chipendo P., Chibnik L.B., Aubin C., Tran D., Keenan B.T., Kramer P.L., Schneider J.A., Bennett D.A., Feany M.B., De Jager P.L. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am. J. Hum. Genet. 2011, 88:232-238.
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 232-238
-
-
Shulman, J.M.1
Chipendo, P.2
Chibnik, L.B.3
Aubin, C.4
Tran, D.5
Keenan, B.T.6
Kramer, P.L.7
Schneider, J.A.8
Bennett, D.A.9
Feany, M.B.10
De Jager, P.L.11
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