A recombinant raccoon poxvirus vaccine expressing both Yersinia pestis f1 and truncated v antigens protects animals against lethal plague

Vaccines

Volumn 2, Issue 4, 2014, Pages 772-784

  Rocke, Tonie E ^a   Kingstad Bakke, Brock ^b   Berlier, Willy ^b   Osorio, Jorge E ^b  

^a NATIONAL WILDLIFE HEALTH CENTER   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Plague; Prairie dogs; Raccoon poxvirus; Vaccine; Yersinia pestis

Indexed keywords

BACTERIAL ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2C; PLAGUE VACCINE; RECOMBINANT RACCOON POXVIRUS VACCINE; UNCLASSIFIED DRUG; VIRUS VECTOR; YERSINIA PESTIS F1 ANTIGEN; YERSINIA PESTIS TRUNCATED V307 ANTIGEN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CYNOMYS; ENZYME LINKED IMMUNOSORBENT ASSAY; HAPLORHINI; IMMUNE RESPONSE; IMMUNOGENICITY; LD 50; MOUSE; NONHUMAN; PLAGUE; POLYMERASE CHAIN REACTION; POXVIRUS; PROTEIN EXPRESSION; RAT; SEROLOGY; SURVIVAL RATE; VACCINATION; VACCINE PRODUCTION; WESTERN BLOTTING;

EID: 84908459368     PISSN: None     EISSN: 2076393X     Source Type: Journal    
DOI: 10.3390/vaccines2040772     Document Type: Article

References (18)

1. Gage, K.L.; Kosoy, M.Y. Natural history of plague: Perspectives from more than a century of research. Annu. Rev. Entomol. 2005, 50, 505–528.
2. Matchett, M.R.; Biggins, D.E.; Carlson, V.; Powell, B.; Rocke, T.E. Enzootic plague reduces black-footed ferret (Mustela nigripes) survival in Montana. Vector-Borne Zoonotic Dis. 2010, 10, 27–35.
3. Brochier, B.; Aubert, M.F.; Pastoret, P.P.; Masson, E.; Schon, J.; Lombard, M.; Chappuis, G.; Languet, B.; Desmettre, P. Field use of a vaccinia-rabies recombinant vaccine for the control of sylvatic rabies in Europe and North America. Rev. Sci. Tech. 1996, 15, 947–970.
4. Slate, D.; Algeo, T.P.; Nelson, K.M.; Chipman, R.B.; Donovan, D.; Blanton, J.D.; Niezgoda, M.; Rupprecht, C.E. Oral rabies vaccination in North America: Opportunities, complexities, and challenges. PLoS Negl. Trop. Dis. 2009, 3, e549.
5. Osorio, J.E.; Powell, T.D.; Frank, R.S.; Moss, K.; Haanes, E.J.; Smith, S.R.; Rocke, T.E.; Stinchcomb, D.T. Recombinant raccoon pox vaccine protects mice against lethal plague. Vaccine 2003, 11–12, 1232–1238.
6. Rocke, T.E.; Pussini, N.; Smith, S.R.; Williamson, J.; Powell, B.; Osorio, J.E. Consumption of baits containing raccoon pox-based plague vaccines protects black-tailed prairie dogs (Cynomys ludovicianus). Vector Borne Zoonotic Dis. 2010, 10, 53–58.
7. Mencher, J.S.; Smith, S.R.; Powell, T.D.; Stinchcomb, D.T.; Osorio, J.E.; Rocke, T.E. Protection of black-tailed prairie dogs (Cynomys ludovicianus) against plague after voluntary consumption of baits containing recombinant raccoon poxvirus vaccine. Infect. Immun. 2004, 72, 5502–5505.
8. Brewoo, J.; Powell, T.; Stinchcomb, D.; Osorio, J. Efficacy and safety of a modified vaccinia Ankara (MVA) vectored plague vaccine in mice. Vaccine 2010, 28, 5891–5899.
9. Rocke, T.E.; Iams, K.; Dawe, S.; Smith, S.; Williamson, J.; Heisey, D.; Osorio, J.E. Further development of raccoon poxvirus-vectored vaccines against plague (Yersinia pestis). Vaccine 2010, 28, 338–344.
10. Herman, Y. Isolation and characterization of a naturally occurring poxvirus of raccoons. In Proceedings of the 64th Annual Meeting of the American Society for Microbiology, Washington, DC, USA, 4 May 1964; p. 117.
11. Rocke, T.E.; Smith, S.R.; Stinchcomb, D.T.; Osorio, J.E. Immunization of black-tailed prairie dogs against plague through consumption of vaccine-laden baits. J. Wildl. Dis. 2008, 44, 930–937.
12. Rocke, T.E. U.S. Geological Survey, National Wildlife Health Center. Unpublished data, 2013.
13. Overheim, K.A.; Depaolo, R.W.; Debord, K.L.; Morrin, E.M.; Anderson, D.M.; Green, N.M.; Brubaker, R.R.; Jabr, I.B.; Schneewind, O. LcrV plague vaccine with altered immunomodulatory properties. Infect. Immun. 2005, 73, 5152–5159.
14. Nakajima, R.; Brubaker, R.R. Association between virulence of Yersinia pestis and suppression of gamma interferon and tumor necrosis factor alpha. Infect. Immun. 1993, 61, 23–31.
15. Nakajima, R.; Motin, V.L.; Brubaker, R.R. Suppression of cytokines in mice by protein A-V antigen fusion peptide and restoration of synthesis by active immunization. Infect. Immun. 1995, 63, 3021–3029.
16. Kingstad-Bakke, B.; Brewoo, J.; Mai le, Q.; Kawaoka, Y.; Osorio, J. Effects of route and coadministration of recombinant raccoon poxviruses on immune responses and protection against highly pathogenic avian influenza in mice. Vaccine 2012, 30, 6402–6048.
17. Rocke, T.E. U.S. Geological Survey, National Wildlife Health Center. Unpublished data, 2010.
18. Gherardi, M.M.; Esteban, M. Mucosal and systemic immune responses induced after oral delivery of vaccinia virus recombinants. Vaccine 1999, 17, 1074–1083.