Pogostone suppresses proinflammatory mediator production and protects against endotoxic shock in mice

Journal of Ethnopharmacology

Volumn 157, Issue , 2014, Pages 212-221

  Li, Yu Cui ^a   Xian, Yan Fang ^b   Su, Zi Ren ^a   Ip, Siu Po ^b   Xie, Jian Hui ^a   Liao, Jin Bin ^a   Wu, Dian Wei ^a   Li, Chu Wen ^a   Chen, Jian Nan ^a   Lin, Zhi Xiu ^b   Lai, Xiao Ping ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

Anti inflammatory property; Inflammatory mediators; MAPKs; NF B; Pogostone

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTIINFLAMMATORY AGENT; ASPARTATE AMINOTRANSFERASE; CYCLOOXYGENASE 2; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL PRODUCT; NITRIC OXIDE; POGOSTONE; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; ESSENTIAL OIL; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LD 50; LIVER INJURY; LUNG INJURY; MACROPHAGE; MALE; MORTALITY; MOUSE; MULTIPLE ORGAN FAILURE; NONHUMAN; POGOSTEMON CABLIN; RESPIRATORY DISTRESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPTIC SHOCK; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMISTRY; CHINESE MEDICINE; DRUG EFFECTS; ISOLATION AND PURIFICATION; LAMIACEAE; LD50; METABOLISM; SHOCK, SEPTIC;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; INFLAMMATION MEDIATORS; LAMIACEAE; LETHAL DOSE 50; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MEDICINE, CHINESE TRADITIONAL; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; OILS, VOLATILE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SHOCK, SEPTIC;

EID: 84908452956     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.09.023     Document Type: Article

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