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Volumn 22, Issue 21, 2014, Pages 6297-6304

Synthesis and activity of new triphenylphosphonium derivatives of betulin and betulinic acid against Schistosoma mansoni in vitro and in vivo

(8) Spivak, Anna Yu a Keiser, Jennifer b,c Vargas, Mireille b,c Gubaidullin, Rinat R a Nedopekina, Darya A a Shakurova, Elvira R a Khalitova, Rezeda R a Odinokov, Victor N a

a INSTITUTE OF PETROCHEMISTRY AND CATALYSIS (Russian Federation)

b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE (Switzerland)

c UNIVERSITY OF BASEL (Switzerland)

Author keywords

Betulin; Betulinic acid; In vitro In vivo; Schistosoma mansoni; Triphenylphosphonium compounds

Indexed keywords

BETULIC ACID; BETULIN; NEW DRUG; PHOSPHINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; TRIPHENYLPHOSPHONIUM DERIVATIVE; UNCLASSIFIED DRUG; ANTHELMINTIC AGENT; ORGANOPHOSPHORUS COMPOUND; TRITERPENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHELMINTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOLERABILITY; FEMALE; IC50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MOUSE MODEL; NONHUMAN; RAT; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; ANIMAL; CHEMISTRY; DRUG EFFECTS; HUMAN; PARASITOLOGY; SYNTHESIS;

ANIMALS; ANTHELMINTICS; FEMALE; HUMANS; MICE; ORGANOPHOSPHORUS COMPOUNDS; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; TRITERPENES;

EID: 84908419492 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2014.07.014 Document Type: Article

Times cited : (45)

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