Targeted analytical toxicology: Simultaneous determination of 17α-ethynylestradiol and the estrogen-induced vitellogenin biomarker

Environment International

Volumn 74, Issue , 2015, Pages 119-124

  Yang, Fangxing ^a,c   Huang, Wei ^a   Xie, Wei ^a   Lu, Chensheng ^b   Liu, Weiping ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

17 Ethynylestradiol; Environmental toxicology; Protein biomarker; Simultaneous determination; Targeted analytical toxicology; Vitellogenin

Indexed keywords

PROTEINS; PROTEOMICS;

ANALYTICAL TOXICOLOGY; ENVIRONMENTAL TOXICOLOGY; ETHYNYLESTRADIOL; SIMULTANEOUS DETERMINATIONS; VITELLOGENIN;

BIOMARKERS;

BIOLOGICAL MARKER; ESTROGEN; ETHINYLESTRADIOL; VITELLOGENIN; POLLUTANT;

BIOMARKER; CONCENTRATION (COMPOSITION); CYPRINID; ESTROGENIC COMPOUND; MOLECULAR ANALYSIS; PHYSIOLOGICAL RESPONSE; PROTEOMICS; TOXICOLOGY;

ADULT; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; HORMONE DETERMINATION; MALE; MEASUREMENT ACCURACY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEOMICS; REPRODUCIBILITY; SENSITIVITY ANALYSIS; TARGETED ANALYTICAL TOXICOLOGY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ZEBRA FISH; ANALYSIS; ANIMAL; BIOSYNTHESIS; ECOTOXICOLOGY; LIQUID CHROMATOGRAPHY; METABOLISM; POLLUTANT; PROCEDURES; TANDEM MASS SPECTROMETRY;

ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; ECOTOXICOLOGY; ENVIRONMENTAL POLLUTANTS; ESTROGENS; ETHINYL ESTRADIOL; MALE; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; VITELLOGENINS; ZEBRAFISH;

EID: 84908401964     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2014.10.015     Document Type: Article

References (12)

1. Bluemlein K., Ralser M. Monitoring protein expression in whole-cell extracts by targeted label- and standard-free LC-MS/MS. Nat. Protoc. 2011, 6:859-869.
2. Castleberry C.M., Limbach P.A. Relative quantitation of transfer RNAs using liquid chromatography mass spectrometry and signature digestion products. Nucleic Acids Res. 2010, 38:e162.
3. Cheek A.O., Brouwer T.H., Carroll S., Manning S., Mclachlan J.A., Brouwer M. Experimental evaluation of vitellogenin as a predictive biomarker for reproductive disruption. Environ. Health Perspect. 2001, 109:681-690.
4. Deutsch E.W., Lam H., Aebersold R. PeptideAtlas: a resource of target selection for emerging targeted proteomics workflows. EMBO Rep. 2008, 9:429-434.
5. Heppell S.A., Denslow N.D., Folmar L.C., Sullivan C.V. Universal assay of vitellogenin as a biomarker for environmental estrogens. Environ. Health Perspect. 1995, 103(Suppl. 7):9-15.
6. Little D.P. Braun Andreas, O'Donnell MJ, Köster H. Mass spectrometry from miniaturized arrays for full comparative DNA analysis. Nat. Methods 1997, 3:1413-1416.
7. Marx V. Targeted proteomics. Nat. Methods 2013, 10:19-22.
8. Ronan J.M., McHugh B. A sensitive liquid chromatography/tandem mass spectrometry method for the determination of natural and synthetic steroid estrogens in seawater and marine biota, with a focus on proposed Water Framework Directive Environmental Quality Standards. Rapid Commun. Mass Spectrom. 2013, 27:738-746.
9. Silva de Assis H.C., Simmons D.B.D., Zamora J.M., Lado W.E., Al-Ansari A.M., Sherry J.P., Blais J.M., Metcalfe C.D., Trudeau V.L. Estrogen-like effects in male goldfish co-exposed to fluoxetine and 17 alpha-ethinylestradiol. Environ. Sci. Technol. 2013, 47:5372-5382.
10. Tyler C.R., van der Eerden B., Jobling S., Panter G., Sumpter J.P. Measurement of vitellogenin, a biomarker for exposure to exstrogenic chemicals, in a wide variety of cyprinid fish. J. Comp. Physiol. B. 1996, 166:418-426.
11. Velasco-Santamaría Y.M., Bjerregaard P., Korsgaard B. Evidence of small modulation of ethinylestradiol induced effects by concurrent exposure to trenbolone in male eelpout Zoarces viviparous. Environ. Pollut. 2013, 178:189-196.
12. Wang Q., Chaerkady R., Wu J., Hwang H.J., Papadopoulos N., Kopelovich L., Maitra A., Matthaei H., Eshleman J.R., Hruban R.H., Kinzler K.W., Pander A., Kinzler K.W. Mutant proteins as cancer-specific biomarkers. Proc Natl Am Sci 2011, 108:2444-2449.