The beneficial effect of abatacept in lupus nephritis may include stabilization of β1 integrin activation in podocytes and treg cell repopulation: Comment on the article by Furie et al

Arthritis and Rheumatology

Volumn 66, Issue 10, 2014, Pages 2913-2914

  Shin, Jae Il ^a   Park, Se Jin ^b   Saleem, Moin A ^c  

^a Yonsei University College of Medicine   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; BETA1 INTEGRIN; GLUCOCORTICOID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; ANTIBODY CONJUGATE; IMMUNOSUPPRESSIVE AGENT;

CELL ACTIVATION; CELL POPULATION; DRUG EFFICACY; DRUG SAFETY; HUMAN; LETTER; LUPUS ERYTHEMATOSUS NEPHRITIS; PODOCYTE; PROTEIN STABILITY; REGULATORY T LYMPHOCYTE; FEMALE; LUPUS NEPHRITIS; MALE;

FEMALE; HUMANS; IMMUNOCONJUGATES; IMMUNOSUPPRESSIVE AGENTS; LUPUS NEPHRITIS; MALE;

EID: 84908388887     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38740     Document Type: Letter

References (6)

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2. Reiser J, Alachkar N,. Proteinuria: abate or applaud abatacept in proteinuric kidney disease? Nat Rev Nephrol 2014; 10: 128-30.
3. Reiser J, von Gersdorff G, Loos M, Oh J, Asanuma K, Giardino L, et al. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest 2004; 113: 1390-7.
4. Yu CC, Fornoni A, Weins A, Hakroush S, Maiguel D, Sageshima J, et al. Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med 2013; 369: 2416-23.
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