Dexmedetomidine as an anesthetic adjuvant for intracranial procedures: Meta-analysis of randomized controlled trials

Journal of Clinical Neuroscience

Volumn 21, Issue 11, 2014, Pages 1951-1958

  Peng, Ke ^a   Wu, Shaoru ^a   Liu, Huayue ^a   Ji, Fuhai ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Craniotomy; Dexmedetomidine; General anesthesia; Intracranial surgery; Neurosurgical procedures

Indexed keywords

DEXMEDETOMIDINE; PLACEBO; REMIFENTANIL; ANTIEMETIC AGENT; CENTRAL DEPRESSANT AGENT; HYPNOTIC SEDATIVE AGENT; NARCOTIC ANALGESIC AGENT;

ADJUVANT THERAPY; ANESTHETIC RECOVERY; ARTICLE; BRADYCARDIA; BRAIN SURGERY; CLINICAL EFFECTIVENESS; CONTINUOUS INFUSION; DRUG EFFICACY; DRUG SAFETY; DRUG USE; EXTUBATION; HEART RATE; HEMODYNAMIC MONITORING; HUMAN; HYPERTENSION; HYPOTENSION; MEAN ARTERIAL PRESSURE; META ANALYSIS; PEROPERATIVE CARE; POSTOPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SURGICAL RISK; SYSTEMATIC REVIEW; TACHYCARDIA; BLOOD PRESSURE; BRAIN; DRUG EFFECTS; INTRAOPERATIVE PERIOD; NEUROSURGERY; ODDS RATIO; POSTOPERATIVE PERIOD; PROCEDURES; SURGERY;

ADJUVANTS, ANESTHESIA; ANALGESICS, OPIOID; ANTIEMETICS; BLOOD PRESSURE; BRAIN; DEXMEDETOMIDINE; HEART RATE; HUMANS; HYPERTENSION; HYPNOTICS AND SEDATIVES; HYPOTENSION; INTRAOPERATIVE PERIOD; NEUROSURGICAL PROCEDURES; ODDS RATIO; POSTOPERATIVE PERIOD; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84908360026     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2014.02.023     Document Type: Article

References (34)

1. A. Basali, E.J. Mascha, and I. Kalfas Relation between perioperative hypertension and intracranial hemorrhage after craniotomy Anesthesiology 93 2000 48 54
2. C. Fieschi, A. Agnoli, and N. Battistini Derangement of regional cerebral blood flow and of its regulatory mechanisms in acute cerebrovascular lesions Neurology 18 1968 1166 1179
3. A. Bekker, and M.K. Sturaitis Dexmedetomidine for neurological surgery Neurosurgery 57 2005 1 10 [discussion 1-10]
4. J.R. Cormack, R.M. Orme, and T.G. Costello The role of alpha2-agonists in neurosurgery J Clin Neurosci 12 2005 375 378
5. D. Moher, A. Liberati, and J. Tetzlaff Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement BMJ 339 2009 b2535
6. A. Schnabel, C.H. Meyer-Frießem, and S.U. Reichl Is intraoperative dexmedetomidine a new option for postoperative pain treatment? A meta-analysis of randomized controlled trials Pain 154 2013 1140 1149
7. N. Elia, and M.R. Tramèr Ketamine and postoperative pain - a quantitative systematic review of randomised trials Pain 113 2005 61 70
8. A.R. Jadad, R.A. Moore, and D. Carroll Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17 1996 1 12
9. R.P. Kaushal, D. Gupta, and B. Kaushal Study to assess the role of dexmedetomidine in patients with intracranial tumors undergoing craniotomy under general anesthesia J Evol Med Dent Sci 2 2013 8305 8313
10. X.H. Gu, and C.Y. Wang Effects of dexmedetomidine on responses during the recovery from general anesthesia in clipping of intracranial aneurysm Chin J New Drugs 21 2012 1010-2+5
11. R.N. Soliman, A.R. Hassan, and A.M. Rashwan Prospective, randomized controlled study to assess the role of dexmedetomidine in patients with supratentorial tumors undergoing craniotomy under general anesthesia Middle East J Anesthesiol 21 2011 23 33
12. N. Turgut, A. Turkmen, and A. Ali Remifentanil-propofol vs dexmedetomidine-propofol - anesthesia for supratentorial craniotomy Middle East J Anesthesiol 20 2009 63 70
13. M. Gunduz, Y. Gunes, and H. Ozbek Comparison of dexmedetomidine or remifentanil infusion combined with sevoflurane anesthesia in craniotomy: hemodynamic variables and recovery Neurosurg Q 19 2009 116 119
14. A.S. Uyar, H. Yagmurdur, and Y. Fidan Dexmedetomidine attenuates the hemodynamic and neuroendocrinal responses to skull-pin head-holder application during craniotomy J Neurosurg Anesthesiol 20 2008 174 179
15. A. Bekker, M. Sturaitis, and M. Bloom The effect of dexmedetomidine on perioperative hemodynamics in patients undergoing craniotomy Anesth Analg 107 2008 1340 1347
16. P.E. Tanskanen, J.V. Kyttä, and T.T. Randell Dexmedetomidine as an anaesthetic adjuvant in patients undergoing intracranial tumour surgery: a double-blind, randomized and placebo-controlled study Br J Anaesth 97 2006 658 665
17. K.S. Olsen, C.B. Pedersen, and J.B. Madsen Vasoactive modulators during and after craniotomy: relation to postoperative hypertension J Neurosurg Anesthesiol 14 2002 171 179
18. A.Y. Bekker, J. Basile, and M. Gold Dexmedetomidine for awake carotid endarterectomy: efficacy, hemodynamic profile, and side effects J Neurosurg Anesthesiol 16 2004 126 135
19. P. Talke, R. Chen, and B. Thomas The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery Anesth Analg 90 2000 834 839
20. Z.P. Khan, I.T. Munday, and R.M. Jones Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: Pharmacodynamic and pharmacokinetic interactions Br J Anaesth 83 1999 372 380
21. R. Aantaa, M.L. Jaakola, and A. Kallio Reduction of the minimum alveolar concentration of isoflurane by dexmedetomidine Anesthesiology 86 1997 1055 1060
22. M. Aho, O. Erkola, and A. Kallio Dexmedetomidine infusion for maintenance of anesthesia in patients undergoing abdominal hysterectomy Anesth Analg 75 1992 940 946
23. J.E. Hall, T.D. Uhrich, and J.A. Barney Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions Anesth Analg 90 2000 699 705
24. T.J. Ebert, J.E. Hall, and J.A. Barney The effects of increasing plasma concentrations of dexmedetomidine in humans Anesthesiology 93 2000 382 394
25. K. Leslie, S. Troedel, and K. Irwin Quality of recovery from anesthesia in neurosurgical patients Anesthesiology 99 2003 1158 1165
26. J.M. Fabling, T.J. Gan, and H.E. El-Moalem A randomized, double-blinded comparison of ondansetron, droperidol, and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy Anesth Analg 91 2000 358 361
27. G. Blaudszun, C. Lysakowski, and N. Elia Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials Anesthesiology 116 2012 1312 1322
28. T. Iirola, H. Ihmsen, and R. Laitio Population pharmacokinetics of dexmedetomidine during long-term sedation in intensive care patients Br J Anaesth 108 2012 460 468
29. T. Iirola, R. Aantaa, and R. Laitio Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients Crit Care 15 2011 R257
30. P.J. Devereaux, and D.I. Sessler The potential role of α(2) agonists for noncardiac surgery Anesthesiology 116 2012 1192 1194
31. J.P. Coles, T.S. Leary, and J.N. Monteiro Propofol anesthesia for craniotomy: a double-blind comparison of remifentanil, alfentanil, and fentanyl J Neurosurg Anesthesiol 12 2000 15 20
32. G. Balakrishnan, P. Raudzens, and S.K. Samra A comparison of remifentanil and fentanyl in patients undergoing surgery for intracranial mass lesions Anesth Analg 91 2000 163 169
33. J. Guy, B.J. Hindman, and K.Z. Baker Comparison of remifentanil and fentanyl in patients undergoing craniotomy for supratentorial space-occupying lesions Anesthesiology 86 1997 514 524
34. D.S. Warner, B.J. Hindman, and M.M. Todd Intracranial pressure and hemodynamic effects of remifentanil versus alfentanil in patients undergoing supratentorial craniotomy Anesth Analg 83 1996 348 353