Increased intravitreous interleukin-18 correlated to vascular endothelial growth factor in patients with active proliferative diabetic retinopathy

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 252, Issue 8, 2014, Pages 1229-1234

  Song, Zongming ^a   Sun, Min ^b   Zhou, Fen ^a   Huang, Fang ^a   Qu, Jia ^a   Chen, Ding ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b Jinin Polytechnic Institute   (China)

Author keywords

Interleukin 18; Proliferative diabetic retinopathy; Vascular endothelial growth factor

Indexed keywords

HEMOGLOBIN A1C; INTERLEUKIN 18; VASCULOTROPIN; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; INTERLEUKIN 18 PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

AGED; ANGIOGENESIS; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DEMOGRAPHY; DIABETIC PATIENT; DIABETIC RETINOPATHY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIRETINAL MEMBRANE; FEMALE; HOSPITAL PATIENT; HUMAN; HUMAN TISSUE; LIQUID; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RETINA MACULA HOLE; RETINA NEOVASCULARIZATION; TISSUE LEVEL; VITRECTOMY; VITREOUS BODY; ARTERIAL PRESSURE; METABOLISM; MIDDLE AGED;

ARTERIAL PRESSURE; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INTERLEUKIN-18; MALE; MIDDLE AGED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITRECTOMY; VITREOUS BODY;

EID: 84908357189     PISSN: 0721832X     EISSN: 1435702X     Source Type: Journal    
DOI: 10.1007/s00417-014-2586-6     Document Type: Article

References (27)

1. Adamis AP, Miller JW, Bernal MT et al (1994) Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol 118:445-450 (Pubitemid 24307211)
2. Aiello LP, Avery RL, Arrigg PG et al (1994) Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 331:1480-1487 (Pubitemid 24356306)
3. Mahdy RA, Nada WM, Hadhoud KM, El-Tarhony SA (2010) The role of vascular endothelial growth factor in the progression of diabetic vascular complications. Eye 24:1576-1584
4. Matsunaga N, Chikaraishi Y, Izuta H et al (2008) Role of soluble vascular endothelial growth factor receptor-1 in the vitreous in proliferative diabetic retinopathy. Ophthalmology 115:1916-1922
5. Chen E, Park CH (2006) Use of intravitreal bevacizumab as a preoperative adjunct for tractional retinal detachment repair in severe proliferative diabetic retinopathy. Retina 26:699-700 (Pubitemid 44620378)
6. di Lauro R, De Ruggiero P, di Lauro R et al (2010) Intravitreal bevacizumab for surgical treatment of severe proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 248:785-791
7. Chung EJ, Kang SJ, Koo JS et al (2011) Effect of intravitreal bevacizumab on vascular endothelial growth factor expression in patients with proliferative diabetic retinopathy. Yonsei Med J 52:151-157
8. Joussen AM, Poulaki V, Le ML et al (2004) A central role for inflammation in the pathogenesis of diabetic retinopathy. Faseb J 18:1450-1452 (Pubitemid 39561611)
9. Spijkerman AM, Gall MA, Tarnow L et al (2007) Endothelial dysfunction and low-grade inflammation and the progression of retinopathy in Type 2 diabetes. Diabet Med 24:969-976 (Pubitemid 47301646)
10. van Hecke MV, Dekker JM, Nijpels G et al (2005) Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study. Diabetologia 48:1300-1306 (Pubitemid 41186094)
11. Forooghian F, Kertes PJ, Eng KT et al (2010) Alterations in the intraocular cytokine milieu after intravitreal bevacizumab. Invest Ophthalmol Vis Sci 51:2388-2392
12. Puren AJ, Fantuzzi G, Dinarello CA (1999) Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells. Proc Natl Acad Sci USA 96:2256-2261 (Pubitemid 29117901)
13. Skopinski P, Rogala E, Duda-Krol B et al (2005) Increased interleukin-18 content and angiogenic activity of sera from diabetic (Type 2) patients with background retinopathy. J Diabetes Complicat 19:335-338 (Pubitemid 41563016)
14. Qiao H, Sonoda KH, Ikeda Y et al (2007) Interleukin-18 regulates pathological intraocular neovascularization. J Leukocyte Biol 81:1012-1021 (Pubitemid 46495650)
15. Amin MA, Mansfield PJ, Pakozdi A et al (2007) Interleukin-18 induces angiogenic factors in rheumatoid arthritis synovial tissue fibroblasts via distinct signaling pathways. Arth Rheum 56:1787-1797 (Pubitemid 47110378)
16. Cho ML, Jung YO, Moon YM et al (2006) Interleukin-18 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways. Immunol Lett 103:159-166 (Pubitemid 43162931)
17. Chorostowska-Wynimko J, Skopinski P, Szaflik J et al (2005) In vitro angiomodulatory activity of sera from type 2 diabetic patients with background retinopathy. J Physiol Pharmacol 56(Suppl 4):65-70 (Pubitemid 43142764)
18. Hernandez C, Burgos R, Canton A et al (2001) Vitreous levels of vascular cell adhesion molecule and vascular endothelial growth factor in patients with proliferative diabetic retinopathy: a case - control study. Diabetes Care 24:516-521 (Pubitemid 32198423)
19. Burgos R, Simo R, Audi L et al (1997) Vitreous levels of vascular endothelial growth factor are not influenced by its serum concentrations in diabetic retinopathy. Diabetologia 40:1107-1109 (Pubitemid 27381975)
20. Kuiper EJ, Van Nieuwenhoven FA, de Smet MD et al (2007) The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy. PloS One 3:e2675
21. Cui JZ, Chiu A, Maberley D et al (2007) Stage specificity of novel growth factor expression during development of proliferative vitreoretinopathy. Eye 21:200-208 (Pubitemid 46454598)
22. Gerdes N, Sukhova GK, Libby P et al (2002) Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis. J Exp Med 195:245-257 (Pubitemid 34461268)
23. Takahashi HK, Iwagaki H, Hamano R et al (2007) Effects of adenosine on adhesion molecule expression and cytokine production in human PBMC depend on the receptor subtype activated. Br J Pharmacol 150:816-822 (Pubitemid 46440211)
24. Canetti CA, Leung BP, Culshaw S et al (2003) IL-18 enhances collagen-induced arthritis by recruiting neutrophils via TNF-alpha and leukotriene B4. J Immunol 171:1009-1015 (Pubitemid 36871417)
25. Aso Y, Okumura K, Takebayashi K et al (2003) Relationships of plasma interleukin-18 concentrations to hyperhomocysteinemia and carotid intimal-media wall thickness in patients with type 2 diabetes. Diabetes Care 26:2622-2627 (Pubitemid 37052110)
26. Nakamura A, Shikata K, Hiramatsu M et al (2005) Serum interleukin-18 levels are associated with nephropathy and atherosclerosis in Japanese patients with type 2 diabetes. Diabetes Care 28:2890-2895 (Pubitemid 43942920)
27. Park CC, Morel JC, Amin MA et al (2001) Evidence of IL-18 as a novel angiogenic mediator. J Immunol 167:1644-1653 (Pubitemid 32703167)