-
1
-
-
0018600123
-
Warfarin sodium versus low-dose heparin in the long-term treatment of venous thrombosis
-
R. Hull, T. Delmore, E. Genton, J. Hirsh, M. Gent, and D. Sackett Warfarin sodium versus low-dose heparin in the long-term treatment of venous thrombosis N Engl J Med 301 16 1979 855 858
-
(1979)
N Engl J Med
, vol.301
, Issue.16
, pp. 855-858
-
-
Hull, R.1
Delmore, T.2
Genton, E.3
Hirsh, J.4
Gent, M.5
Sackett, D.6
-
2
-
-
23844524855
-
Relation between quality of anticoagulant treatment and the development of the postthrombotic syndrome
-
C.J. van Dongen, P. Prandoni, M. Frulla, A. Marchiori, M.H. Prins, and B.A. Hutten Relation between quality of anticoagulant treatment and the development of the postthrombotic syndrome J Thromb Haemost 3 5 2005 939 942
-
(2005)
J Thromb Haemost
, vol.3
, Issue.5
, pp. 939-942
-
-
Van Dongen, C.J.1
Prandoni, P.2
Frulla, M.3
Marchiori, A.4
Prins, M.H.5
Hutten, B.A.6
-
3
-
-
0037171819
-
Structure-based design of novel potent nonpeptide thrombin inhibitors
-
N.H. Hauel, H. Nar, H. Priepke, U. Ries, J.M. Stassen, and W. Wienen Structure-based design of novel potent nonpeptide thrombin inhibitors J Med Chem 45 9 2002 1757 1766
-
(2002)
J Med Chem
, vol.45
, Issue.9
, pp. 1757-1766
-
-
Hauel, N.H.1
Nar, H.2
Priepke, H.3
Ries, U.4
Stassen, J.M.5
Wienen, W.6
-
4
-
-
22844442726
-
In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939 - An oral, direct Factor Xa inhibitor
-
E. Perzborn, J. Strassburger, A. Wilmen, J. Pohlmann, S. Roehrig, and K.H. Schlemmer In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939 - an oral, direct Factor Xa inhibitor J Thromb Haemost 3 3 2005 514 521
-
(2005)
J Thromb Haemost
, vol.3
, Issue.3
, pp. 514-521
-
-
Perzborn, E.1
Strassburger, J.2
Wilmen, A.3
Pohlmann, J.4
Roehrig, S.5
Schlemmer, K.H.6
-
5
-
-
24944536065
-
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide (BAY 59-7939): An oral, direct factor Xa inhibitor
-
S. Roehrig, A. Straub, J. Pohlmann, T. Lampe, J. Pernerstorfer, and K.H. Schlemmer Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor J Med Chem 48 19 2005 5900 5908
-
(2005)
J Med Chem
, vol.48
, Issue.19
, pp. 5900-5908
-
-
Roehrig, S.1
Straub, A.2
Pohlmann, J.3
Lampe, T.4
Pernerstorfer, J.5
Schlemmer, K.H.6
-
6
-
-
35848929515
-
Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa
-
D.J. Pinto, M.J. Orwat, S. Koch, K.A. Rossi, R.S. Alexander, and A. Smallwood Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa J Med Chem 50 22 2007 5339 5356
-
(2007)
J Med Chem
, vol.50
, Issue.22
, pp. 5339-5356
-
-
Pinto, D.J.1
Orwat, M.J.2
Koch, S.3
Rossi, K.A.4
Alexander, R.S.5
Smallwood, A.6
-
7
-
-
49849099533
-
DU-176b, a potent and orally active factor Xa inhibitor: In vitro and in vivo pharmacological profiles
-
T. Furugohri, K. Isobe, Y. Honda, C. Kamisato-Matsumoto, N. Sugiyama, and T. Nagahara DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles J Thromb Haemost 6 9 2008 1542 1549
-
(2008)
J Thromb Haemost
, vol.6
, Issue.9
, pp. 1542-1549
-
-
Furugohri, T.1
Isobe, K.2
Honda, Y.3
Kamisato-Matsumoto, C.4
Sugiyama, N.5
Nagahara, T.6
-
8
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
S. Schulman, C. Kearon, A.K. Kakkar, P. Mismetti, S. Schellong, and H. Eriksson Dabigatran versus warfarin in the treatment of acute venous thromboembolism N Engl J Med 361 24 2009 2342 2352
-
(2009)
N Engl J Med
, vol.361
, Issue.24
, pp. 2342-2352
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
Mismetti, P.4
Schellong, S.5
Eriksson, H.6
-
9
-
-
78650619315
-
Oral rivaroxaban for symptomatic venous thromboembolism
-
The EINSTEIN Investigators Oral rivaroxaban for symptomatic venous thromboembolism N Engl J Med 363 26 2010 2499 2510
-
(2010)
N Engl J Med
, vol.363
, Issue.26
, pp. 2499-2510
-
-
-
10
-
-
84859385808
-
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism
-
The EINSTEIN-PE Investigators Oral rivaroxaban for the treatment of symptomatic pulmonary embolism N Engl J Med 366 14 2012 1287 1297
-
(2012)
N Engl J Med
, vol.366
, Issue.14
, pp. 1287-1297
-
-
-
11
-
-
84874003257
-
Extended use of dabigatran, warfarin, or placebo in venous thromboembolism
-
S. Schulman, C. Kearon, A.K. Kakkar, S. Schellong, H. Eriksson, and D. Baanstra Extended use of dabigatran, warfarin, or placebo in venous thromboembolism N Engl J Med 368 8 2013 709 718
-
(2013)
N Engl J Med
, vol.368
, Issue.8
, pp. 709-718
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
Schellong, S.4
Eriksson, H.5
Baanstra, D.6
-
12
-
-
84873596181
-
Apixaban for extended treatment of venous thromboembolism
-
G. Agnelli, H.R. Buller, A. Cohen, M. Curto, A.S. Gallus, and M. Johnson Apixaban for extended treatment of venous thromboembolism N Engl J Med 368 8 2013 699 708
-
(2013)
N Engl J Med
, vol.368
, Issue.8
, pp. 699-708
-
-
Agnelli, G.1
Buller, H.R.2
Cohen, A.3
Curto, M.4
Gallus, A.S.5
Johnson, M.6
-
13
-
-
84880327613
-
Oral apixaban for the treatment of acute venous thromboembolism
-
G. Agnelli, H.R. Buller, A. Cohen, M. Curto, A.S. Gallus, and M. Johnson Oral apixaban for the treatment of acute venous thromboembolism N Engl J Med 369 2013 799 808
-
(2013)
N Engl J Med
, vol.369
, pp. 799-808
-
-
Agnelli, G.1
Buller, H.R.2
Cohen, A.3
Curto, M.4
Gallus, A.S.5
Johnson, M.6
-
14
-
-
84885618705
-
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism
-
The Hokusai-VTE Investigators Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism N Engl J Med 369 15 2013 1406 1415
-
(2013)
N Engl J Med
, vol.369
, Issue.15
, pp. 1406-1415
-
-
-
15
-
-
84894295323
-
Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis
-
S. Schulman, A.K. Kakkar, S.Z. Goldhaber, S. Schellong, H. Eriksson, and P. Mismetti Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis Circulation 129 7 2014 764 772
-
(2014)
Circulation
, vol.129
, Issue.7
, pp. 764-772
-
-
Schulman, S.1
Kakkar, A.K.2
Goldhaber, S.Z.3
Schellong, S.4
Eriksson, H.5
Mismetti, P.6
-
16
-
-
23044505564
-
Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients
-
S. Schulman, and C. Kearon Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients J Thromb Haemost 3 4 2005 692 694
-
(2005)
J Thromb Haemost
, vol.3
, Issue.4
, pp. 692-694
-
-
Schulman, S.1
Kearon, C.2
-
17
-
-
34548768174
-
Idraparinux versus standard therapy for venous thromboembolic disease
-
The van Gogh Investigators Idraparinux versus standard therapy for venous thromboembolic disease N Engl J Med 357 11 2007 1094 1104
-
(2007)
N Engl J Med
, vol.357
, Issue.11
, pp. 1094-1104
-
-
-
18
-
-
84869838484
-
Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: Direct and adjusted indirect meta-analysis of randomised controlled trials
-
B.D. Fox, S.R. Kahn, D. Langleben, M.J. Eisenberg, and A. Shimony Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled trials BMJ 345 2012 e7498
-
(2012)
BMJ
, vol.345
, pp. 7498
-
-
Fox, B.D.1
Kahn, S.R.2
Langleben, D.3
Eisenberg, M.J.4
Shimony, A.5
-
19
-
-
84864410509
-
Dabigatran, rivaroxaban and apixaban versus enoxaparin for thomboprophylaxis after total knee or hip arthroplasty: Pool-analysis of phase III randomized clinical trials
-
J.A. Nieto, N.G. Espada, R.G. Merino, and T.C. Gonzalez Dabigatran, rivaroxaban and apixaban versus enoxaparin for thomboprophylaxis after total knee or hip arthroplasty: pool-analysis of phase III randomized clinical trials Thromb Res 130 2 2012 183 191
-
(2012)
Thromb Res
, vol.130
, Issue.2
, pp. 183-191
-
-
Nieto, J.A.1
Espada, N.G.2
Merino, R.G.3
Gonzalez, T.C.4
-
20
-
-
84896117299
-
Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: A meta-analysis of randomised trials
-
C.T. Ruff, R.P. Giugliano, E. Braunwald, E.B. Hoffman, N. Deenadayalu, and M.D. Ezekowitz Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials Lancet 383 9921 2014 955 962
-
(2014)
Lancet
, vol.383
, Issue.9921
, pp. 955-962
-
-
Ruff, C.T.1
Giugliano, R.P.2
Braunwald, E.3
Hoffman, E.B.4
Deenadayalu, N.5
Ezekowitz, M.D.6
-
21
-
-
84896741977
-
Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: A systematic review and meta-analysis
-
T. van der Hulle, J. Kooiman, P.L. den Exter, O.M. Dekkers, F.A. Klok, and M.V. Huisman Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: a systematic review and meta-analysis J Thromb Haemost 12 3 2014 320 328
-
(2014)
J Thromb Haemost
, vol.12
, Issue.3
, pp. 320-328
-
-
Van Der Hulle, T.1
Kooiman, J.2
Den Exter, P.L.3
Dekkers, O.M.4
Klok, F.A.5
Huisman, M.V.6
-
22
-
-
84880333928
-
Meta-analysis of rivaroxaban and bleeding risk
-
G. Wasserlauf, S.M. Grandi, K.B. Filion, and M.J. Eisenberg Meta-analysis of rivaroxaban and bleeding risk Am J Cardiol 112 3 2013 454 460
-
(2013)
Am J Cardiol
, vol.112
, Issue.3
, pp. 454-460
-
-
Wasserlauf, G.1
Grandi, S.M.2
Filion, K.B.3
Eisenberg, M.J.4
-
23
-
-
84870937596
-
Nonvitamin-K-antagonist oral anticoagulants in patients with atrial fibrillation and previous stroke or transient ischemic attack: A systematic review and meta-analysis of randomized controlled trials
-
G. Ntaios, V. Papavasileiou, H.C. Diener, K. Makaritsis, and P. Michel Nonvitamin-K-antagonist oral anticoagulants in patients with atrial fibrillation and previous stroke or transient ischemic attack: a systematic review and meta-analysis of randomized controlled trials Stroke 43 12 2012 3298 3304
-
(2012)
Stroke
, vol.43
, Issue.12
, pp. 3298-3304
-
-
Ntaios, G.1
Papavasileiou, V.2
Diener, H.C.3
Makaritsis, K.4
Michel, P.5
-
24
-
-
84869236631
-
Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: A systematic review and meta-analysis of the literature
-
F. Dentali, N. Riva, M. Crowther, A.G. Turpie, G.Y. Lip, and W. Ageno Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature Circulation 126 20 2012 2381 2391
-
(2012)
Circulation
, vol.126
, Issue.20
, pp. 2381-2391
-
-
Dentali, F.1
Riva, N.2
Crowther, M.3
Turpie, A.G.4
Lip, G.Y.5
Ageno, W.6
-
25
-
-
84889880439
-
Cost-effectiveness of rivaroxaban versus warfarin anticoagulation for the prevention of recurrent venous thromboembolism: A U.S. Perspective
-
C.D. Seaman, K.J. Smith, and M.V. Ragni Cost-effectiveness of rivaroxaban versus warfarin anticoagulation for the prevention of recurrent venous thromboembolism: a U.S. perspective Thromb Res 132 6 2013 647 651
-
(2013)
Thromb Res
, vol.132
, Issue.6
, pp. 647-651
-
-
Seaman, C.D.1
Smith, K.J.2
Ragni, M.V.3
-
26
-
-
84890450192
-
Cost-effectiveness of rivaroxaban compared with enoxaparin plus a vitamin K antagonist for the treatment of venous thromboembolism
-
P. Lefebvre, C.I. Coleman, B.K. Bookhart, S.T. Wang, S.H. Mody, and K.N. Tran Cost-effectiveness of rivaroxaban compared with enoxaparin plus a vitamin K antagonist for the treatment of venous thromboembolism J Med Econ 17 1 2014 52 64
-
(2014)
J Med Econ
, vol.17
, Issue.1
, pp. 52-64
-
-
Lefebvre, P.1
Coleman, C.I.2
Bookhart, B.K.3
Wang, S.T.4
Mody, S.H.5
Tran, K.N.6
-
27
-
-
0042658340
-
Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors: Prospective cohort study
-
T. Baglin, R. Luddington, K. Brown, and C. Baglin Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors: prospective cohort study Lancet 362 9383 2003 523 526
-
(2003)
Lancet
, vol.362
, Issue.9383
, pp. 523-526
-
-
Baglin, T.1
Luddington, R.2
Brown, K.3
Baglin, C.4
-
28
-
-
34249829228
-
The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1,626 patients
-
P. Prandoni, F. Noventa, A. Ghirarduzzi, V. Pengo, E. Bernardi, and R. Pesavento The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1,626 patients Haematologica 92 2 2007 199 205
-
(2007)
Haematologica
, vol.92
, Issue.2
, pp. 199-205
-
-
Prandoni, P.1
Noventa, F.2
Ghirarduzzi, A.3
Pengo, V.4
Bernardi, E.5
Pesavento, R.6
-
29
-
-
84907174827
-
Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism
-
B.A. Hutten, and M.H. Prins Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism Cochrane Database Syst Rev 1 2006 CD001367
-
(2006)
Cochrane Database Syst Rev
, Issue.1
, pp. 001367
-
-
Hutten, B.A.1
Prins, M.H.2
-
30
-
-
84875780959
-
Dabigatran and postmarketing reports of bleeding
-
M.R. Southworth, M.E. Reichman, and E.F. Unger Dabigatran and postmarketing reports of bleeding N Engl J Med 368 14 2013 1272 1274
-
(2013)
N Engl J Med
, vol.368
, Issue.14
, pp. 1272-1274
-
-
Southworth, M.R.1
Reichman, M.E.2
Unger, E.F.3
-
31
-
-
84878051291
-
New oral anticoagulants increase risk for gastrointestinal bleeding: A systematic review and meta-analysis
-
e15-112 e15
-
I.L. Holster, V.E. Valkhoff, E.J. Kuipers, and E.T. Tjwa New oral anticoagulants increase risk for gastrointestinal bleeding: a systematic review and meta-analysis Gastroenterology 145 1 2013 105 e15 112 e15
-
(2013)
Gastroenterology
, vol.145
, Issue.1
, pp. 105
-
-
Holster, I.L.1
Valkhoff, V.E.2
Kuipers, E.J.3
Tjwa, E.T.4
-
32
-
-
84857021520
-
Dabigatran association with higher risk of acute coronary events: Meta-analysis of noninferiority randomized controlled trials
-
K. Uchino, and A.V. Hernandez Dabigatran association with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials Arch Intern Med 172 5 2012 397 402
-
(2012)
Arch Intern Med
, vol.172
, Issue.5
, pp. 397-402
-
-
Uchino, K.1
Hernandez, A.V.2
-
33
-
-
84878460192
-
A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa
-
G. Lu, F.R. DeGuzman, S.J. Hollenbach, M.J. Karbarz, K. Abe, and G. Lee A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa Nat Med 19 4 2013 446 451
-
(2013)
Nat Med
, vol.19
, Issue.4
, pp. 446-451
-
-
Lu, G.1
Deguzman, F.R.2
Hollenbach, S.J.3
Karbarz, M.J.4
Abe, K.5
Lee, G.6
-
34
-
-
79960810062
-
Long-term low-molecular-weight heparin and the post-thrombotic syndrome: A systematic review
-
R.D. Hull, J. Liang, and G. Townshend Long-term low-molecular-weight heparin and the post-thrombotic syndrome: a systematic review Am J Med 124 8 2011 756 765
-
(2011)
Am J Med
, vol.124
, Issue.8
, pp. 756-765
-
-
Hull, R.D.1
Liang, J.2
Townshend, G.3
|