Association between subclinical hypothyroidism and diabetic nephropathy in patients with type 2 diabetes mellitus

Endocrine Journal

Volumn 61, Issue 10, 2014, Pages 1011-1018

  Furukawa, Shinya ^a   Yamamoto, Shin ^a   Todo, Yasuhiko ^a   Maruyama, Kotatsu ^a   Miyake, Teruki ^a   Ueda, Teruhisa ^a   Niiya, Tetsuji ^b   Senba, Takatoshi ^b   Torisu, Masamoto ^c   Kumagi, Teru ^a   Miyauchi, Syozo ^d   Sakai, Takenori ^e   Minami, Hisaka ^f   Miyaoka, Hiroaki ^g   Matsuura, Bunzo ^a   Hiasa, Yoichi ^a   Onji, Morikazu ^h   Tanigawa, Takeshi ^a,i  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Matsuyama Shimin Hospital   (Japan)

^c Saiseikai Saijo Hospital   (Japan)

^d Department of Neurosurgery Uwajima City Hospital   (Japan)

^e Department of Internal Medicine Yawatahama General City Hospital   (Japan)

^f Department of Cardiology Ehime Niihama Prefectural Hospital   (Japan)

^g Department of Internal Medicine Saiseikai Matsuyama Hospital   (Japan)

^h Department of Internal Medicine Saiseikai Imabari Hospital   (Japan)

ⁱ JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Dyslipidemia; Kidney; Metabolic disease; Microvascular disease; Thyroid stimulating hormone

Indexed keywords

ALBUMIN; CREATININE; THYROID HORMONE; THYROTROPIN;

ADULT; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; DYSLIPIDEMIA; EUTHYROIDISM; FEMALE; HUMAN; HYPERTENSION; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; SMOKING; SUBCLINICAL HYPOTHYROIDISM; THYROID DISEASE; THYROID HORMONE BLOOD LEVEL; THYROTROPIN BLOOD LEVEL; AGED; BLOOD; CLINICAL TRIAL; COMORBIDITY; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DYSLIPIDEMIAS; HYPOTHYROIDISM; MULTICENTER STUDY; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; COMORBIDITY; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DYSLIPIDEMIAS; FEMALE; HUMANS; HYPOTHYROIDISM; MALE; MIDDLE AGED; PREVALENCE; THYROTROPIN; YOUNG ADULT;

EID: 84908345677     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ14-0206     Document Type: Article

References (33)

1. McDermott MT, Ridgway EC (2001) Subclinical hypothyroidism is mild thyroid failure and should be treated. J Clin Endocrinol Metab 86:4585-4590.
2. Taddei S, Caraccio N, Virdis A, Dardano A, Versari D, et al. (2003) Impaired endothelium-dependent vasodilatation in subclinical hypothyroidism: beneficial effect of levothyroxine therapy. J Clin Endocrinol Metab 88:3731-3737.
3. Biondi B, Galderisi M, Pagano L, Sidiropulos M, Pulcrano M, et al. (2009) Endothelial-mediated coronary flow reserve in patients with mild thyroid hormone deficiency. Eur J Endocrinol 161:323-329.
4. Biondi B, Fazio S, Palmieri EA, Carella C, Panza N, et al. (1999) Left ventricular diastolic dysfunction in patients with subclinical hypothyroidism. J Clin Endocrinol Metab 84:2064-2067.
5. Canaris GJ, Manowitz NR, Mayor G, Ridgway EC (2000) The Colorado thyroid disease prevalence study. Arch Intern Med 160:526-534.
6. Feely J, Isles TE (1979) Screening for thyroid dysfunction in diabetics. Br Med J 1:1678.
7. Perros P, McCrimmon RJ, Shaw G, Frier BM (1995) Frequency of thyroid dysfunction in diabetic patients: value of annual screening. Diabet Med 12:622-627.
8. Smithson MJ (1998) Screening for thyroid dysfunction in a community population of diabetic patients. Diabet Med 15:148-150.
9. Chonchol M, Lippi G, Salvagno G, Zoppini G, Muggeo M, et al. (2008) Prevalence of subclinical hypothyroidism in patients with chronic kidney disease. Clin J Am Soc Nephrol 3:1296-1300.
10. Lo JC, Chertow GM, Go AS, Hsu CY (2005) Increased prevalence of subclinical and clinical hypothyroidism in persons with chronic kidney disease. Kidney Int 67:1047-1052.
11. Shin DH, Lee MJ, Kim SJ, Oh HJ, Kim HR, et al. (2012) Preservation of renal function by thyroid hormone replacement therapy in chronic kidney disease patients with subclinical hypothyroidism. J Clin Endocrinol Metab 97:2732-2740.
12. Kim BY, Kim CH, Jung CH, Mok JO, Suh KI, et al. (2011) Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes. Endocr J 58:1065-1070.
13. Yasuda T, Kaneto H, Kuroda A, Yamamoto T, Takahara M, et al. (2011) Subclinical hypothyroidism is independently associated with albuminuria in people with type 2 diabetes. Diabetes Res Clin Pract 94:e75-e77.
14. Chen HS, Wu TE, Jap TS, Lu RA, Wang ML, et al. (2007) Subclinical hypothyroidism is a risk factor for nephropathy and cardiovascular diseases in Type 2 diabetic patients. Diabet Med 24:1336-1344.
15. Japan Nephrology Society (2012) Clinical practice guidebook for diagnosis and treatment of chronic kidney disease 2012. Nihon Jinzo Gakkai Shi 54:1034-1191. (In Japanese)
16. Gross JL, de Azevedo MJ, Silveiro SP, Canani LH, Caramori ML, et al. (2005) Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care 28:164-176.
17. Yang JK, Liu W, Shi J, Li YB (2010) An association between subclinical hypothyroidism and sight-threatening diabetic retinopathy in type 2 diabetic patients. Diabetes Care 33:1018-1020.
18. Ramis JN, Artigas CF, Santiago MA, Mañes FJ, Canonge RS, et al. (2012) Is there a relationship between TSH levels and diabetic retinopathy in the Caucasian population? Diabetes Res Clin Pract 97:e45-e47.
19. Kohler KA, McClellan WM, Ziemer DC, Kleinbaum DG, Boring JR (2000) Risk factors for microalbuminuria in black americans with newly diagnosed type 2 diabetes. Am J Kidney Dis 36:903-913.
20. Asvold BO, Bjøro T, Vatten LJ (2011) Association of thyroid function with estimated glomerular filtration rate in a population-based study: the HUNT study. Eur J Endocrinol 164:101-5.
21. Shin DH, Lee MJ, Lee HS, Oh HJ, Ko KI, et al. (2013) Thyroid hormone replacement therapy attenuates the decline of renal function in chronic kidney disease patients with subclinical hypothyroidism. Thyroid 23:654-661.
22. Saini V, Yadav A, Arora MK, Arora S, Singh R, et al. (2012) Correlation of creatinine with TSH levels in overt hypothyroidism - a requirement for monitor ing of renal function in hypothyroid patients? Clin Biochem 45: 212-4.
23. Saito K, Sone H, Kawai K, Tanaka S, Kodama S, et al. (2007) Risk imparted by various parameters of smoking in Japanese men with type 2 diabetes on their development of microalbuminuria: analysis from the Tsukuba Kawai Diabetes Registry. Diabetes Care 30: 1286-1288.
24. UK Prospective Diabetes Study Group (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 317: 703-713.
25. Appel GB, Radhakrishnan J, Avram MM, DeFronzo RA, Escobar-Jimenez F, et al. (2003) Analysis of metabolic parameters as predictors of risk in the RENAAL study. Diabetes Care 26: 1402-1407.
26. Althaus BU, Staub JJ, Ryff-De Lèche A, Oberhänsli A, Stähelin HB. (1988) LDL/HDL-changes in subclinical hypothyroidism: possible risk factors for coronary heart disease. Clin Endocrinol (Oxf) 28: 157-163.
27. Staub JJ, Althaus BU, Engler H, Ryff AS, Trabucco P, et al. (1992) Spectrum of subclinical and overt hypothyroidism: effect on thyrotropin, prolactin, and thyroid reserve, and metabolic impact on peripheral target tissues. Am J Med 92: 631-642.
28. Mariani LH, Berns JS. (2012) The renal manifestations of thyroid disease. J Am Soc Nephrol 23: 22-26.
29. Lim VS (2001) Thyroid function in patients with chronic renal failure. Am J Kidney Dis 38: S80-S84.
30. Duntas LH (2002) Thyroid disease and lipids. Thyroid 12: 287-293.
31. Nakajima Y, Yamada M, Akuzawa M, Ishii S, Masamura Y, et al. (2013) Subclinical hypothyroidism and indices for metabolic syndrome in Japanese women: one-year follow-up study. J Clin Endocrinol Metab 98: 3280-3287.
32. Pallas D, Koutras DA, Adamopoulos P, Marafelia P, Souvatzoglou A, et al. (1991) Increased mean serum thyrotropin in apparently euthyroid hypercholesterolemic patients: does it mean occult hypothyroidism? J Endocrinol Invest 14: 743-746.
33. Caraccio N, Ferrannini E, Monzani F (2002) Lipoprotein profile in subclinical hypothyroidism: response to levothyroxine replacement, a randomized placebo-controlled study. J Clin Endocrinol Metab 87: 1533-1538.