Prevalence of the fosfomycin-resistance determinant, FosB3, In Enterococcus faecium clinical isolates from China

Journal of Medical Microbiology

Volumn 63, Issue , 2014, Pages 1484-1489

  Chen, Chunhui ^a   Xu, Xiaogang ^a   Qu, Tingting ^b   Yu, Yunsong ^b   Ying, Chunmei ^c   Liu, Qinzhong ^d   Guo, Qinglan ^a   Hu, Fupin ^a   Zhu, Demei ^a   Li, Guanghui ^a   Wang, Minggui ^a  

^a FUDAN UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; BACTERIAL DNA; CHLORAMPHENICOL; CIRCULAR DNA; DNA FRAGMENT; DOXYCYCLINE; ERYTHROMYCIN; FOSFOMYCIN; GENTAMICIN; LEVOFLOXACIN; LINEZOLID; RIFAMPICIN; SPACER DNA; TEICOPLANIN; VANCOMYCIN; BACTERIAL PROTEIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CHINA; CONJUGATION; ENTEROCOCCUS FAECIUM; GENE SEQUENCE; GENOTYPE; INVERSE POLYMERASE CHAIN REACTION; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR PHYLOGENY; MOLECULAR TYPING; MULTILOCUS SEQUENCE TYPING; NONHUMAN; TRANSPOSON; VANCOMYCIN RESISTANT ENTEROCOCCUS; EPIDEMIOLOGY; GENETICS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMAN; METABOLISM; MICROBIOLOGY;

BACTERIAL PROTEINS; CHINA; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS FAECIUM; FOSFOMYCIN; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; VANCOMYCIN;

EID: 84908322966     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.077701-0     Document Type: Article

References (24)

1. Allerberger, F. & Klare, I. (1999). In vitro activity of fosfomycin against vancomycin-resistant enterococci. J Antimicrob Chemother 43, 211–217.
2. Barbier, N., Saulnier, P., Chachaty, E., Dumontier, S. & Andremont, A. (1996). Random amplified polymorphic DNA typing versus pulsed-field gel electrophoresis for epidemiological typing of vancomycin-resistant enterococci. J Clin Microbiol 34, 1096–1099.
3. Butcu, M., Akcay, S. S., Aksaray, S., Calisici, G., Inan, A. S. & Engin, D. O. (2011). In vitro susceptibility of enterococci strains isolated from urine samples to fosfomycin and other antibiotics. J Infect Chemother 17, 575–578.
4. Cao, M., Bernat, B. A., Wang, Z., Armstrong, R. N. & Helmann, J. D. (2001). FosB, a cysteine-dependent fosfomycin resistance protein under the control of sigma(W), an extracytoplasmic-function sigma factor in Bacillus subtilis. J Bacteriol 183, 2380–2383.
5. Carriço, J. A., Pinto, F. R., Simas, C., Nunes, S., Sousa, N. G., Frazão, N., de Lencastre, H. & Almeida, J. S. (2005). Assessment of bandbased similarity coefficients for automatic type and subtype classification of microbial isolates analyzed by pulsed-field gel electrophoresis. J Clin Microbiol 43, 5483–5490.
6. CLSI (2010). Performance Standards for Antimicrobial Susceptibility Testing; 20th Informational Supplement M100–S20. Wayne, PA: Clinical and Laboratory Standards Institute.
7. d’Azevedo, P. A., Dias, C. A. & Teixeira, L. M. (2006). Genetic diversity and antimicrobial resistance of enterococcal isolates from Southern region of Brazil. Rev Inst Med Trop Sao Paulo 48, 11–16.
8. Feil, E. J., Li, B. C., Aanensen, D. M., Hanage, W. P. & Spratt, B. G. (2004). eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J Bacteriol 186, 1518–1530.
9. Franke, A. E. & Clewell, D. B. (1981). Evidence for a chromosomeborne resistance transposon (Tn916) in Streptococcus faecalis that is capable of ‘‘conjugal’’ transfer in the absence of a conjugative plasmid. J Bacteriol 145, 494–502.
10. Homan, W. L., Tribe, D., Poznanski, S., Li, M., Hogg, G., Spalburg, E., Van Embden, J. D. & Willems, R. J. (2002). Multilocus sequence typing scheme for Enterococcus faecium. J Clin Microbiol 40, 1963–1971.
11. Kahan, F. M., Kahan, J. S., Cassidy, P. J. & Kropp, H. (1974). The mechanism of action of fosfomycin (phosphonomycin). Ann N Y Acad Sci 235, 364–386.
12. Lamers, A. P., Keithly, M. E., Kim, K., Cook, P. D., Stec, D. F., Hines, K. M., Sulikowski, G. A. & Armstrong, R. N. (2012). Synthesis of bacillithiol and the catalytic selectivity of FosB-type fosfomycin resistance proteins. Org Lett 14, 5207–5209.
13. Michalopoulos, A. S., Livaditis, I. G. & Gougoutas, V. (2011). The revival of fosfomycin. Int J Infect Dis 15, e732–e739.
14. Perri, M. B., Hershberger, E., Ionescu, M., Lauter, C. & Zervos, M. J. (2002). In vitro susceptibility of vancomycin-resistant enterococci (VRE) to fosfomycin. Diagn Microbiol Infect Dis 42, 269–271.
15. Qu, T. T., Yang, Q., Shen, P., Wei, Z. Q. & Yu, Y. S. (2012). Novel vancomycin-resistance transposon, plasmid replicon types, and virulence factors of vancomycin-resistant enterococci in Zhejiang, China. Microb Drug Resist 18, 183–188.
16. Rigsby, R. E., Fillgrove, K. L., Beihoffer, L. A. & Armstrong, R. N. (2005). Fosfomycin resistance proteins: a nexus of glutathione transferases and epoxide hydrolases in a metalloenzyme superfamily. Methods Enzymol 401, 367–379.
17. Sahni, R. D., Balaji, V., Varghese, R., John, J., Tansarli, G. S. & Falagas, M. E. (2013). Evaluation of fosfomycin activity against uropathogens in a fosfomycin-naive population in South India: a prospective study. Future Microbiol 8, 675–680.
18. Sun, H., Wang, H., Xu, Y., Jones, R. N., Costello, A. J., Liu, Y., Li, G., Chen, M. & Mendes, R. E. (2012). Molecular characterization of vancomycin-resistant Enterococcus spp. clinical isolates recovered from hospitalized patients among several medical institutions in China. Diagn Microbiol Infect Dis 74, 399–403.
19. Wang, F., Zhu, D., Hu, F., Ruan, F., Ni, Y., Sun, J., Xu, Y., Sun, H., Hu, Y. & other authors (2008). CHINET 2007 surveillance of bacterial resistance in China. Chinese Journal of Infection and Chemotherapy 8, 325–332. (in Chinese).
20. Willems, R. J., Top, J., van Santen, M., Robinson, D. A., Coque, T. M., Baquero, F., Grundmann, H. & Bonten, M. J. (2005). Global spread of vancomycin-resistant Enterococcus faecium from distinct nosocomial genetic complex. Emerg Infect Dis 11, 821–828.
21. Xu, X., Lin, D., Yan, G., Ye, X., Wu, S., Guo, Y., Zhu, D., Hu, F., Zhang, Y. & other authors (2010). vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium. Antimicrob Agents Chemother 54, 4643–4647.
22. Xu, H. T., Tian, R., Chen, D. K., Xiao, F., Nie, Z. Y., Hu, Y. J., Zhang, X. Z. & Li, J. M. (2011). Nosocomial spread of hospital-adapted CC17 vancomycin-resistant Enterococcus faecium in a tertiary-care hospital of Beijing, China. Chin Med J (Engl) 124, 498–503.
23. Xu, X., Chen, C., Lin, D., Guo, Q., Hu, F., Zhu, D., Li, G. & Wang, M. (2013). The fosfomycin resistance gene fosB3 is located on a transferable, extrachromosomal circular intermediate in clinical Enterococcus faecium isolates. PLoS ONE 8, e78106.
24. Zilhao, R. & Courvalin, P. (1990). Nucleotide sequence of the fosB gene conferring fosfomycin resistance in Staphylococcus epidermidis. FEMS Microbiol Lett 56, 267–272.