Could myelin damage from radiofrequency electromagnetic field exposure help explain the functional impairment electrohypersensitivity? A review of the evidence

Journal of Toxicology and Environmental Health - Part B: Critical Reviews

Volumn 17, Issue 5, 2014, Pages 247-258

  Redmayne, Mary ^a,b   Johansson, Olle ^c  

^a MONASH UNIVERSITY   (Australia)

^b VICTORIA UNIVERSITY OF WELLINGTON   (New Zealand)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DEATH; DEMYELINATION; ELECTRIC CONDUCTIVITY; ELECTROHYPERSENSITIVITY; ELECTROMAGNETIC FIELD; FEMALE; FETUS; FUNCTIONAL DISEASE; HUMAN; INFANT; MALE; MOBILE PHONE; MULTIPLE SCLEROSIS; MYELIN SHEATH; NERVE CONDUCTION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OPTIC NEURITIS; PERIPHERAL NERVOUS SYSTEM; RADIOFREQUENCY; RAT; RISK; SYMPTOM; ANIMAL; DEMYELINATING DISEASE; PHYSIOLOGY; RADIATION EXPOSURE; RADIOFREQUENCY RADIATION; REVIEW;

ANIMALS; DEMYELINATING DISEASES; ELECTROMAGNETIC FIELDS; HUMANS; MYELIN SHEATH; RADIO WAVES;

EID: 84908302012     PISSN: 10937404     EISSN: 15216950     Source Type: Journal    
DOI: 10.1080/10937404.2014.923356     Document Type: Article

References (55)

1. Anane, R., Geffard, M., Taxile, M., Bodet, D., Billaudel, B., Dulou, P., and Veyret, B. 2003. Effects of gsm-900 microwaves on the experimental allergic encephalomyelitis (eae) rat model of multiple sclerosis. Bioelectromagnetics 24: 211-113.
2. Augner, C., Gnambs, T., Winker, R., and Barth, A. 2012. Acute effects of electromagnetic fields emitted by GSM mobile phones on subjective well-being and physiological reactions: A meta-analysis. Sci. Total Environ. 424: 11-15.
3. Aydin, M. A., Comlekci, S., Ozguner, M., Cesur, G., Nasir, S., and Aydin, Z. D. 2006. The influence of continuous exposure to 50 Hz electric field on nerve regeneration in a rat peroneal nerve crush injury model. Bioelectromagnetics 27: 401-413.
4. Baptista, A. F., Goes, B. T., Menezes, D., Gomes, F. C., Augaib, J., Stipursky, J., Gomes, J. R., Oliveira, J. T., Vannier-Santos, M. A., and Martinez, A. M. 2009. PEMF failsto enhance nerve regeneration after sciatic nerve crush lesion. J. Peripheral Nerv. System 14: 285-293.
5. Baranski, S. 1972. Histological and histochemical effects of microwave irradiation on the central nervous system of rabbits and guinea pigs. Am. J. Physiol. Med. 51: 182-190.
6. Bartzokis, G. 2011. Neuroglialpharmacology: Myelination as a shared mechanism of action of psychotropic treatments. Neuropharmacology 16: 2695-2733.
7. Blakemore, S.-J., and Choudhury, S. 2006. Brain development during puberty: State of the science. Dev. Sci. 9: 11-14.
8. Christ, A., Gosselin, M.-C., Christopoulou, M., Khun, S., and Kuster, N. 2010. Age dependent tissue-specific exposure of cell phone users. Phys. Med. Biol. 55: 1767-1783.
9. ElectroSensitivity United Kingdom. 2014. Recognising ES and EHS. Retrieved 2 March 2014 from http://www.es-uk.info (accessed March 2, 2014).
10. Fuxe, K., Agnati, L. F., Härfstrand, A., Andersson, K., Mascagni, F., Zoli, M., Kalia, M., Battistini, N., Benfenati, F., Hökfelt, T., and Goldstein, M. 1986. New perspectives on the treatment of disorders of the central nervous system. In Peptides and neurological disease, ed. P. C. Emson, M. Rossor, and M. Tohyama. Amsterdam, The Netherlands: Elsevier, 341-368.
11. Gerfen, C. R. 2003. D1 dopamine receptor supersensitivity in the dopamine-depleted striatum animal model of Parkinson's disease. Neuroscientist 9: 455-462.
12. Gordon, Z. V., Lobanova, Y. A., Kitsovskaya, I. A., and Tolgskaya, M. S. 1963. Biological effect of microwaves of low intensity. Med. Electronics Biol. Eng. 1: 67-69.
13. Halgamuge, M. N., and Abeyrathne, C. D. 2011. Behavior of charged particles in a biological cell exposed to AC-DC electromagnetic fields. Environ. Eng. Sci. 28: 1-10.
14. Hardell, L., Carlberg, M., and Hansson Mild, K. 2010. Mobile phone use and the risk for malignant brain tumours: A case-control study on deceased cases and controls. Neuroepidemiology 35: 109-114.
15. Havas, M., and Marrongelle, J. 2013. Replication of heart rate variability provocation study with 2.4 GHz cordless phone confirms original findings. Electromagnet. Biol. Med. 32: 253-266.
16. Health Council of the Netherlands. 2011. Influence of radiofrequency telecommunication signals on children's brains. The Hague, The Netherlands: Health Council of the Netherlands.
17. Hillert, L., Berglin, N., Arnetz, B. B., and Bellander,T.2002.Prevalenceof self-reported hypersensitivity to electric or magnetic fields in a population based questionnaire survey. Scand. J. Work Environ. Health 28: 33-41.
18. Huttenlocher, P. R. 1979. Synaptic density in human frontal cortex: Developmental changes and effects of aging. Brain Res. 163: 195-205.
19. Inomata-Terada, S., Okabe, S., Arai, N., Hanajima, R., Terao, Y., Frubayashi, T., and Ugawa, Y. 2007. Effects of high frequency electromagnetic field (emf) emitted by mobile phones on the human motor cortex. Bioelectromagnetics 28: 553-561.
20. Johansson, O. 2006. Electrohypersensitivity: State-of-the-art of a functional impairment. Electromagnet. Biol. Med. 25: 245-258.
21. Johansson, O., Gangi, S., Liang, Y, Yoshimura, K., Jing, C., and Liu, P.-Y. 2001. Cutaneous mast cells are altered in normal healthy volunteers sitting in front of ordinary TVs/PCs- Result from open-field provocation experiments. J. Cutan. Pathol. 28: 513-519.
22. Johansson, O., and Liu, P. Y. 1995. "Electrosensitivity," "electrosupersensitivity" and "screen dematitis": Preliminary observations from on-going studies in the human skin. In Proceedings of the COST 244: Biomedical effects of electromagnetic fields: workshop on electromagnetic hypersensitivity, ed. D. Simunic, 52-57. Brussels/Graz, Belgium: COST 244.
23. Keshvari, J., Keshvari, R., and Lang, S. 2006. The effect of increase in dielectric values on specific absorption rate (SAR) in eye and head tissues following 900, 1800 and 2450 MHz radio frequency (RF) exposure. Phys. Med. Biol. 51: 1463-1477.
24. Knyazeva, M.G. 2013. Splenium of corpus callosum: Patterns of interhemispheric interaction in children and adults. Neural Plast. 2013.
25. Levallois, P., Neutra, R., Lee, G., and Hristova, L. 2002. Study of self-reported hypersensitivity to electromagnetic fields in california. Environ. Health Perspect. 110(suppl. 4): 619-623.
26. Mar, S. S. 2014. Neurology: Pediatric Multiple Sclerosis and Other Demyelinating Disease Center. http://wuphysicians.wustl.edu/dept.aspx?pageID=46&ID=4 (accessed February 12, 2014).
27. Mert, T., Gunay, I., Gocmen, C., Kaya, M., and Polat, S. 2006. Regenerative effects of pulsed mangetic field on injured peripheral nerves. Altern. Ther. Health Med. 12: 42-49.
28. Multiple Sclerosis Trust. 2014. A-Z of MS. http://www.mstrust.org.uk/atoz/prevalence-incidence.jsp (accessed March 19, 2014).
29. National Institute of Neurological Disorders and Stroke. 2014. NINDS chronic inflammatory demyelinating polyneuropathy (CEDP) information page. http://www.ninds.nih.gov/disorders/cidp/cidp.htm (accessed April 24, 2014).
30. National Multiple Sclerosis Society. 2014. Signs and symptoms consistent with demyelinating disease. http://www.nationalmssociety.org (accessed February 10, 2014).
31. Panagopoulos, D. J., Karabarbounis, A., and Margaritis, L. H. 2002. Mechanism for action of electromagnetic fields on cells. Biochem Biophys Res Commun 298: 95-102.
32. Paus, T., Zijdenbos, A., Worsley, K., Collins, D. L., Blumenthal, J., Giedd, J. N., Rapoport, J. L., and Evans, A. C. 1999. Structural maturation of neural pathways in children and adolescents: in vivo study. Science 283: 1908-1911.
33. Pikov, V., Arakaki, X., Harrington, M., Fraser, S., and Siegel, P. H. 2010. Modulation of neuronal activity and plasma membrane properties with low-power millimeter waves in organotypic cortical slices. J. Neural Eng. 7: 045003.
34. Peinnequin, A., Pioriou, A., Mathieu, J., and Dabouis, V. 2000. Non-thermal effects of continuous 2.45 GHz microwaves on Fasinduced apoptosis in human Jurkat T-cell line. Bioelectrochemistry 51: 157-161.
35. Poulson, A. H., Stenager, E., Johansen, C., Bentzen, J., Friis, S., and Schüz, J. 2012. Mobile phones and multiple sclerosis: A nationwide cohort study in Denmark. PloS One 12: E34453.
36. Protasoni, M., Reguzzoni, M., Sangoirgi, S., Reverberi, C., Baorsani, E., Rodella, L. F., Dario, A., Tomei, G., and Dell'orbo, C. 2009. Pulsed radiofrequency effects on the lumbar ganlion of the rat dorsal root: A morphological light and transmission electron microscopy study at acute stage. Eur. Spine J. 18: 473-478.
37. Rathus, S. A. 2010. Childhood & adolescence: Voyages in development, 4th ed. Florence, KY: Wadsworth.
38. Redmayne, M., Smith, E., and Abramson, M. J. 2013. The relationship between adolescents' well-being and their wireless phone use: A cross-sectional study. Environ. Health 12: 90.
39. Rodier, P. M. 2004. Environmental causes of central nervous system maldevelopment. Pediatrics 113: 1076-1083.
40. Röösli, M., Moser, M., Baldinini, Y. M., Meier, M., and Braun-Fahrländer, C. 2004. Symptoms of ill health ascribed to electromagnetic field exposure: A questionnaire survey. Int. J. Hyg. Environ. Health 207: 141-150.
41. Röösli, M., Frei, P., Mohler, E., and Hug, K. 2010. Systematic review on the health effects of exposure to radiofrequency electromagnetic fields from mobile phone base stations. Bull. WHO. 88: 887-896.
42. Rosati, G. 2001. The prevalence of multiple sclerosis in the world: An update. Neurol. Sci. 22: 117-139.
43. Rubin, G. J., Das-Munshi, J., and Wessely, S. 2005. Electromagnetic hypersensitivity: A systematic review of provocation studies. Psychosom. Med. 67: 224-232.
44. Schneider, M. N., and Pekker, M. 2013. Initiation and blocking of the action potential in the axon in a weak ultrasonic field. Paper 1309.5940, Cornell University Library. file:///C:/Users/mredmayn/Downloads/arXiv1309.5940%20[physics.bio-ph]%20(1).pdf (accessed November 2013).
45. Schreier, N., Huss, A., and Röösli, M. 2006. The prevalence of symptoms attributed to electromagnetic field exposure: A crosssectional representative survey in Switzerland. Soz. Praventiv. Med. 51: 202-209.
46. Schrottner, J., and Leitgeb, N. 2008. Sensitivity to electricity: Temporal changes in Austria. BMC Public Health 8: 310.
47. Schüz, J., Waldemar, G., Olsen, J. H., and Johansen, C. 2007. Risks for central nervous system diseases among mobile phone subscribers: A Danish retrospective cohort study. PLoS One 4: e4389.
48. Sears, M. E. 2007. The medical perspective on environmental sensitivities. In Environmental sensitivities-Medical issues. Ottawa: ON, Canada: Canadian Human Rights Commission. pp. 1-79.
49. Sherafat, M. A., Heibatollahi, M., Mongabadi, S., Moradi, F., Javan, M., and Ahmadiani, A. 2012. Electromagnetic field stimulation potentiates endogenous myelin repair by recruiting subventricular neural stem cells in an experimental model of white matter demyelination. J. Mol. Neurosci. 48: 244-253.
50. Socialstyrelsen (National Board of Health and Welfare, Sweden). 2014. Electromagnetic hypersensitivity. http://www.socialstyrelsen.se/electromagnetichypersensitivity (accessed February 14, 2013).
51. Switzer, W. G., and Mitchell, D. S. 1977. Long-term effects of 2.45 GHz radiation on the ultrastructure of the cerebral cortex and hematologic profiles of rats. Radio Sci. 12: 287-293.
52. Van Rongen, E., Croft, R., Juutilainen, J., Lagroye, I., Miyakoshi, J., Saunders, R., De Seze, R., Tenforde, T., Verschaeve, L., Veyret, B., and Xu, Z. 2009. Effects of radiofrequency electromagnetic fields on the human nervous system. J. Toxicol. Environ. Health B 12: 572-597.
53. Wang, L., Hilliges, M., Jernberg, T., Wiegleb-Edström, D., and Johansson, O. 1990. Protein gene product 9.5-immunoreactive nerve fibres and cells in human skin. Cell Tissue Res. 261: 25-33.
54. Wheeler, M. 2009. Rethinking Alzheimer's disease and its treatment targets. UCLA Newsroom, 22 September. http://newsroom.ucla.edu/releases/new-target-for-alzheimers-102065 (accessed February 2013).
55. Yakovlev, P. I., and Lecours, A. R. 1967. The myelogenetic cycles of regional maturation of the brain. In Regional development of the brain in early life, ed. A. Minkowski, 3-70. Oxford, UK: Blackwell Scientific.