Engineered endolysin-based “Artilysins” to combat multidrug-resistant gram-negative pathogens

mBio

Volumn 5, Issue 4, 2014, Pages

  Briers, Yves ^a   Walmagh, Maarten ^a   Van Puyenbroeck, Victor ^a   Cornelissen, Anneleen ^a   Cenens, William ^b   Aertsen, Abram ^b   Oliveira, Hugo ^c   Azeredo, Joana ^c   Verween, Gunther ^d   Pirnay, Jean Paul ^d   Miller, Stefan ^e   Volckaert, Guido ^a   Lavigne, Rob ^a  

^a LABORATORY OF GENE TECHNOLOGY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY OF MINHO   (Portugal)

^d QUEEN ASTRID MILITARY HOSPITAL   (Belgium)

^e Lisando GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ARTILYSIN; ENDOLYSIN; NONAPEPTIDE; PEPTIDE DERIVATIVE; PEPTIDOGLYCAN; POLYCATION; UNCLASSIFIED DRUG; PROTEINASE;

ACINETOBACTER BAUMANNII; ARTICLE; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; CAENORHABDITIS ELEGANS; CYTOLYSIS; DRUG SCREENING; ENZYME ENGINEERING; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MICROSCOPY; NONHUMAN; OUTER MEMBRANE; PROCESS OPTIMIZATION; PROTEIN DEGRADATION; PSEUDOMONAS AERUGINOSA; TIME LAPSE MICROSCOPY; CHEMISTRY; DRUG EFFECTS; MULTIDRUG RESISTANCE;

NEGIBACTERIA;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENDOPEPTIDASES; PSEUDOMONAS AERUGINOSA;

EID: 84908289926     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01379-14     Document Type: Article

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