Two different scenarios of squamous cell carcinoma within advanced basal cell carcinomas: Cases illustrating the importance of serial biopsy during vismodegib usage
Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib
Chang AL, Solomon JA, Hainsworth JD, et al. Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib. J AmAcad Dermatol. 2014;70(1):60-69.
Phase i trial of Hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors
LoRusso PM, Rudin CM, Reddy JC, et al. Phase I trial of Hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors. Clin Cancer Res. 2011;17(8):2502-2511.
Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice
Kang HC,Wakabayashi Y, Jen KY, et al. Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice. J Invest Dermatol. 2013;133(5):1311-1320.
Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice
Wakabayashi Y, Mao J-H, Brown K, Girardi M, Balmain A. Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice. Nature. 2007;445(7129):761-765.
New onset of keratoacanthomas after vismodegib treatment for locally advanced basal cell carcinomas: A report of 2 cases
Aasi S, Silkiss R, Tang JY, et al. New onset of keratoacanthomas after vismodegib treatment for locally advanced basal cell carcinomas: a report of 2 cases. JAMA Dermatol. 2013;149(2):242-243.
Multiple highly and moderately differentiated squamous cell carcinomas of the skin during vismodegib treatment of inoperable basal cell carcinoma
[published online January 21, 2014]
Orouji A, Goerdt S, Utikal J, Leverkus M. Multiple highly and moderately differentiated squamous cell carcinomas of the skin during vismodegib treatment of inoperable basal cell carcinoma [published online January 21, 2014]. Br J Dermatol. doi:10.1111/bjd.12840.
Basosquamous carcinoma: An underrecognized, high-risk cutaneous neoplasm: Case study and review of the literature
Costantino D, Lowe L, Brown DL. Basosquamous carcinoma: an underrecognized, high-risk cutaneous neoplasm: case study and review of the literature. J Plast Reconstr Aesthet Surg. 2006;59(4):424-428.