-
1
-
-
15944383403
-
Gene-environment interactions in human diseases
-
Hunter, D.J. (2005). Gene-environment interactions in human diseases. Nat. Rev. Genet. 6, 287-298
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 287-298
-
-
Hunter, D.J.1
-
2
-
-
53249113155
-
Gene-environment interactions for complex traits: Definitions, methodological requirements and challenges
-
Dempfle, A., Scherag, A., Hein, R., Beckmann, L., Chang-ClauDe, J., and Schäfer, H. (2008). Gene-environment interactions for complex traits: Definitions, methodological requirements and challenges. Eur. J. Hum. Genet. 16, 1164-1172
-
(2008)
Eur. J. Hum. Genet
, vol.16
, pp. 1164-1172
-
-
Dempfle, A.1
Scherag, A.2
Hein, R.3
Beckmann, L.4
Chang-Claude, J.5
Schäfer, H.6
-
3
-
-
68249108329
-
Prediction and interaction in complex disease genetics: Experience in type 1 diabetes
-
Clayton, D.G. (2009). Prediction and interaction in complex disease genetics: experience in type 1 diabetes. PLoS Genet. 5, e1000540
-
(2009)
PLoS Genet
, vol.5
, pp. e1000540
-
-
Clayton, D.G.1
-
4
-
-
0025959790
-
Effect modification and the limits of biological inference from epiDemiologic data
-
Thompson, W.D. (1991). Effect modification and the limits of biological inference from epiDemiologic data. J. Clin. EpiDemiol. 44, 221-232
-
(1991)
J. Clin. EpiDemiol
, vol.44
, pp. 221-232
-
-
Thompson, W.D.1
-
5
-
-
0033406444
-
Misclassification in case-control studies of gene-environment interactions: Assessment of bias and sample size
-
Garcia-Closas, M., Rothman, N., and Lubin, J. (1999). Misclassification in case-control studies of gene-environment interactions: assessment of bias and sample size. Cancer EpiDemiol. Biomarkers Prev. 8, 1043-1050
-
(1999)
Cancer EpiDemiol. Biomarkers Prev
, vol.8
, pp. 1043-1050
-
-
Garcia-Closas, M.1
Rothman, N.2
Lubin, J.3
-
6
-
-
34548772979
-
Estimating and testing interactions in linear regression moDels when explanatory variables are subject to classical measurement error
-
Murad, H., and Freedman, L.S. (2007). Estimating and testing interactions in linear regression moDels when explanatory variables are subject to classical measurement error. Stat. Med. 26, 4293-4310
-
(2007)
Stat. Med
, vol.26
, pp. 4293-4310
-
-
Murad, H.1
Freedman, L.S.2
-
7
-
-
42249109208
-
Sample size requirements for indirect association studies of gene-environment interactions (G x e
-
Hein, R., Beckmann, L., and Chang-ClauDe, J. (2008). Sample size requirements for indirect association studies of gene-environment interactions (G x E). Genet. EpiDemiol. 32, 235-245
-
(2008)
Genet. EpiDemiol
, vol.32
, pp. 235-245
-
-
Hein, R.1
Beckmann, L.2
Chang-Claude, J.3
-
8
-
-
2642668471
-
Differential misclassification and the assessment of gene-environment interactions in case-control studies
-
García-Closas, M., Thompson, W.D., and Robins, J.M. (1998). Differential misclassification and the assessment of gene-environment interactions in case-control studies. Am. J. EpiDemiol. 147, 426-433
-
(1998)
Am. J. EpiDemiol
, vol.147
, pp. 426-433
-
-
García-Closas, M.1
Thompson, W.D.2
Robins, J.M.3
-
9
-
-
33746406822
-
The impact of imprecisely measured covariates on estimating gene-environment interactions
-
Greenwood, D.C., Gilthorpe, M.S., and CaDe, J.E. (2006). The impact of imprecisely measured covariates on estimating gene-environment interactions. BMC Med. Res. Methodol. 6, 21
-
(2006)
BMC Med. Res. Methodol
, vol.6
, pp. 21
-
-
Greenwood, D.C.1
Gilthorpe, M.S.2
Cade, J.E.3
-
10
-
-
0028089404
-
Nonhierarchical logistic moDels and case-only Designs for assessing susceptibility in population-based case-control studies
-
Piegorsch, W.W., Weinberg, C.R., and Taylor, J.A. (1994). Nonhierarchical logistic moDels and case-only Designs for assessing susceptibility in population-based case-control studies. Stat. Med. 13, 153-162
-
(1994)
Stat. Med
, vol.13
, pp. 153-162
-
-
Piegorsch, W.W.1
Weinberg, C.R.2
Taylor, J.A.3
-
11
-
-
49749089301
-
Exploiting geneenvironment inDepenDence for analysis of case-control studies: An empirical Bayes-type shrinkage estimator to traDe-off between bias and efficiency
-
Mukherjee, B., and Chatterjee, N. (2008). Exploiting geneenvironment inDepenDence for analysis of case-control studies: an empirical Bayes-type shrinkage estimator to traDe-off between bias and efficiency. Biometrics 64, 685-694
-
(2008)
Biometrics
, vol.64
, pp. 685-694
-
-
Mukherjee, B.1
Chatterjee, N.2
-
12
-
-
84881611825
-
Finding novel genes by testing G 3 e interactions in a genome-wiDe association study
-
GauDerman, W.J., Zhang, P., Morrison, J.L., and Lewinger, J.P. (2013). Finding novel genes by testing G 3 E interactions in a genome-wiDe association study. Genet. EpiDemiol. 37, 603-613
-
(2013)
Genet. EpiDemiol
, vol.37
, pp. 603-613
-
-
Gauderman, W.J.1
Zhang, P.2
Morrison, J.L.3
Lewinger, J.P.4
-
13
-
-
84860741280
-
A general framework for two-stage analysis of genome-wiDe association studies and its application to case-control studies
-
Wason, J.M., and Dudbridge, F. (2012). A general framework for two-stage analysis of genome-wiDe association studies and its application to case-control studies. Am. J. Hum. Genet. 90, 760-773
-
(2012)
Am. J. Hum. Genet
, vol.90
, pp. 760-773
-
-
Wason, J.M.1
Dudbridge, F.2
-
14
-
-
84869473073
-
Two-stage testing procedures with inDepenDent filtering for genome-wiDe gene-environment interaction
-
Dai, J.Y., Kooperberg, C., Leblanc, M., and Prentice, R.L. (2012). Two-stage testing procedures with inDepenDent filtering for genome-wiDe gene-environment interaction. Biometrika 99, 929-944
-
(2012)
Biometrika
, vol.99
, pp. 929-944
-
-
Dai, J.Y.1
Kooperberg, C.2
Leblanc, M.3
Prentice, R.L.4
-
15
-
-
85016045726
-
Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: A case-control study
-
Johnson, N., Dudbridge, F., Orr, N., Gibson, L., Jones, M.E., Schoemaker, M.J., Folkerd, E.J., Haynes, B.P., Hopper, J.L., Southey, M.C., et al. (2014). Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study. Breast Cancer Res. 16, R51
-
(2014)
Breast Cancer Res
, vol.16
, pp. R51
-
-
Johnson, N.1
Dudbridge, F.2
Orr, N.3
Gibson, L.4
Jones, M.E.5
Schoemaker, M.J.6
Folkerd, E.J.7
Haynes, B.P.8
Hopper, J.L.9
Southey, M.C.10
-
16
-
-
84862190418
-
CYP3A variation, premenopausal estrone levels, and breast cancer risk
-
Johnson, N., Walker, K., Gibson, L.J., Orr, N., Folkerd, E., Haynes, B., Palles, C., Coupland, B., Schoemaker, M., Jones, M., et al. (2012). CYP3A variation, premenopausal estrone levels, and breast cancer risk. J. Natl. Cancer Inst. 104, 657-669
-
(2012)
J. Natl. Cancer Inst
, vol.104
, pp. 657-669
-
-
Johnson, N.1
Walker, K.2
Gibson, L.J.3
Orr, N.4
Folkerd, E.5
Haynes, B.6
Palles, C.7
Coupland, B.8
Schoemaker, M.9
Jones, M.10
-
17
-
-
84875735063
-
EviDence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors
-
Genica Network; kConFab; AOCS Management Group
-
Nickels, S., Truong, T., Hein, R., Stevens, K., Buck, K., Behrens, S., Eilber, U., Schmidt, M., Häberle, L., Vrieling, A., et al.; Genica Network; kConFab; AOCS Management Group (2013). EviDence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors. PLoS Genet. 9, e1003284
-
(2013)
PLoS Genet
, vol.9
, pp. e1003284
-
-
Nickels, S.1
Truong, T.2
Hein, R.3
Stevens, K.4
Buck, K.5
Behrens, S.6
Eilber, U.7
Schmidt, M.8
Häberle, L.9
Vrieling, A.10
-
18
-
-
41649103052
-
A variant associated with nicotine DepenDence, lung cancer and peripheral arterial disease
-
Thorgeirsson, T.E., Geller, F., Sulem, P., Rafnar, T., Wiste, A., Magnusson, K.P., Manolescu, A., Thorleifsson, G., Stefansson, H., Ingason, A., et al. (2008). A variant associated with nicotine DepenDence, lung cancer and peripheral arterial disease. Nature 452, 638-642
-
(2008)
Nature
, vol.452
, pp. 638-642
-
-
Thorgeirsson, T.E.1
Geller, F.2
Sulem, P.3
Rafnar, T.4
Wiste, A.5
Magnusson, K.P.6
Manolescu, A.7
Thorleifsson, G.8
Stefansson, H.9
Ingason, A.10
-
19
-
-
55749093830
-
The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine DepenDence and for lung cancer
-
Spitz, M.R., Amos, C.I., Dong, Q., Lin, J., and Wu, X. (2008). The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine DepenDence and for lung cancer. J. Natl. Cancer Inst. 100, 1552-1556
-
(2008)
J. Natl. Cancer Inst
, vol.100
, pp. 1552-1556
-
-
Spitz, M.R.1
Amos, C.I.2
Dong, Q.3
Lin, J.4
Wu, X.5
-
20
-
-
77957366301
-
Multiple inDepenDent loci at chromosome 15q25.1 affect smoking quantity: A meta-Analysis and comparison with lung cancer and COPD
-
Saccone, N.L., Culverhouse, R.C., Schwantes-An, T.H., Cannon, D.S., Chen, X., Cichon, S., Giegling, I., Han, S., Han, Y., Keskitalo-Vuokko, K., et al. (2010). Multiple inDepenDent loci at chromosome 15q25.1 affect smoking quantity: a meta-Analysis and comparison with lung cancer and COPD. PLoS Genet. 6, 6
-
(2010)
PLoS Genet
, vol.6
, pp. 6
-
-
Saccone, N.L.1
Culverhouse, R.C.2
Schwantes-An, T.H.3
Cannon, D.S.4
Chen, X.5
Cichon, S.6
Giegling, I.7
Han, S.8
Han, Y.9
Keskitalo-Vuokko, K.10
-
21
-
-
84861413864
-
Genetic variants on 15q25.1, smoking, and lung cancer: An assessment of mediation and interaction
-
VanDerWeele, T.J., Asomaning, K., Tchetgen Tchetgen, E.J., Han, Y., Spitz, M.R., Shete, S., Wu, X., Gaborieau, V., Wang, Y., McLaughlin, J., et al. (2012). Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction. Am. J. EpiDemiol. 175, 1013-1020
-
(2012)
Am. J. EpiDemiol
, vol.175
, pp. 1013-1020
-
-
Vanderweele, T.J.1
Asomaning, K.2
Tchetgen Tchetgen, E.J.3
Han, Y.4
Spitz, M.R.5
Shete, S.6
Wu, X.7
Gaborieau, V.8
Wang, Y.9
McLaughlin, J.10
-
22
-
-
77951751034
-
Meta-Analysis and imputation refines the association of 15q25 with smoking quantity Wellcome Trust Case Control Consortium
-
Liu, J.Z., Tozzi, F., Waterworth, D.M., Pillai, S.G., Muglia, P., Middleton, L., Berrettini, W., Knouff, C.W., Yuan, X., Waeber, G., et al.; Wellcome Trust Case Control Consortium (2010). Meta-Analysis and imputation refines the association of 15q25 with smoking quantity. Nat. Genet. 42, 436-440
-
(2010)
Nat. Genet
, vol.42
, pp. 436-440
-
-
Liu, J.Z.1
Tozzi, F.2
Waterworth, D.M.3
Pillai, S.G.4
Muglia, P.5
Middleton, L.6
Berrettini, W.7
Knouff, C.W.8
Yuan, X.9
Et Al., W.G.10
-
23
-
-
21344469970
-
The genetics of addictions: Uncovering the genes
-
Goldman, D., Oroszi, G., and Ducci, F. (2005). The genetics of addictions: uncovering the genes. Nat. Rev. Genet. 6, 521-532
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 521-532
-
-
Goldman, D.1
Oroszi, G.2
Ducci, F.3
-
24
-
-
77950670865
-
The relation between different dimensions of alcohol consumption and burDen of disease: An overview
-
Rehm, J., Baliunas, D., Borges, G.L., Graham, K., Irving, H., Kehoe, T., Parry, C.D., Patra, J., Popova, S., Poznyak, V., et al. (2010). The relation between different dimensions of alcohol consumption and burDen of disease: an overview. Addiction 105, 817-843
-
(2010)
Addiction
, vol.105
, pp. 817-843
-
-
Rehm, J.1
Baliunas, D.2
Borges, G.L.3
Graham, K.4
Irving, H.5
Kehoe, T.6
Parry, C.D.7
Patra, J.8
Popova, S.9
Poznyak, V.10
-
25
-
-
78049337953
-
Association analyses of 249, 796 individuals reveal 18 new loci associated with body mass inDex
-
MAGIC; Procardis Consortium
-
Speliotes, E.K., Willer, C.J., Berndt, S.I., Monda, K.L., Thorleifsson, G., Jackson, A.U., Lango Allen, H., Lindgren, C.M., Luan, J., Mägi, R., et al.; MAGIC; Procardis Consortium (2010). Association analyses of 249, 796 individuals reveal 18 new loci associated with body mass inDex. Nat. Genet. 42, 937-948
-
(2010)
Nat. Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
Monda, K.L.4
Thorleifsson, G.5
Jackson, A.U.6
Lango Allen, H.7
Lindgren, C.M.8
Luan, J.9
Mägi, R.10
-
26
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
Global Lipids Genetics Consortium
-
Willer, C.J., Schmidt, E.M., Sengupta, S., Peloso, G.M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., Buchkovich, M.L., Mora, S., et al.; Global Lipids Genetics Consortium (2013). Discovery and refinement of loci associated with lipid levels. Nat. Genet. 45, 1274-1283
-
(2013)
Nat. Genet
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
Schmidt, E.M.2
Sengupta, S.3
Peloso, G.M.4
Gustafsson, S.5
Kanoni, S.6
Ganna, A.7
Chen, J.8
Buchkovich, M.L.9
Mora, S.10
-
27
-
-
81355151686
-
Associations of FTO and MC4R variants with obesity traits in Indians and the role of rural/urban environment as a possible effect modifier
-
Taylor, A.E., SanDeep, M.N., Janipalli, C.S., Giambartolomei, C., EVans, D.M., Kranthi Kumar, M.V., Vinay, D.G., Smitha, P., Gupta, V., Aruna, M., et al. (2011). Associations of FTO and MC4R variants with obesity traits in Indians and the role of rural/urban environment as a possible effect modifier. J. Obes. 2011, 307542
-
(2011)
J. Obes
, vol.2011
, pp. 307542
-
-
Taylor, A.E.1
Sandeep, M.N.2
Janipalli, C.S.3
Giambartolomei, C.4
Evans, D.M.5
Kranthi Kumar, M.V.6
Vinay, D.G.7
Smitha, P.8
Gupta, V.9
Aruna, M.10
-
28
-
-
0036499241
-
Sample size requirements for association studies of gene-gene interaction
-
GauDerman, W.J. (2002). Sample size requirements for association studies of gene-gene interaction. Am. J. EpiDemiol. 155, 478-484
-
(2002)
Am. J. EpiDemiol
, vol.155
, pp. 478-484
-
-
Gauderman, W.J.1
-
29
-
-
53749089552
-
A genomewiDe linkage scan for age at menarche in three populations of European Descent
-
AnDerson, C.A., Zhu, G., Falchi, M., Van Den Berg, S.M., Treloar, S.A., Spector, T.D., Martin, N.G., Boomsma, D.I., Visscher, P.M., and Montgomery, G.W. (2008). A genomewiDe linkage scan for age at menarche in three populations of European Descent. J. Clin. Endocrinol. Metab. 93, 3965-3970
-
(2008)
J. Clin. Endocrinol. Metab
, vol.93
, pp. 3965-3970
-
-
Anderson, C.A.1
Zhu, G.2
Falchi, M.3
Van Den Berg, S.M.4
Treloar, S.A.5
Spector, T.D.6
Martin, N.G.7
Boomsma, D.I.8
Visscher, P.M.9
Montgomery, G.W.10
-
30
-
-
79851487367
-
Synthetic associations created by rare variants do not explain most GWAS results
-
Wray, N.R., Purcell, S.M., and Visscher, P.M. (2011). Synthetic associations created by rare variants do not explain most GWAS results. PLoS Biol. 9, e1000579
-
(2011)
PLoS Biol
, vol.9
, pp. e1000579
-
-
Wray, N.R.1
Purcell, S.M.2
Visscher, P.M.3
-
31
-
-
84900302836
-
Detection and replication of epistasis influencing transcription in humans
-
Hemani, G., Shakhbazov, K., Westra, H.J., Esko, T., HenDers, A.K., McRae, A.F., Yang, J., Gibson, G., Martin, N.G., Metspalu, A., et al. (2014). Detection and replication of epistasis influencing transcription in humans. Nature 508, 249-253
-
(2014)
Nature
, vol.508
, pp. 249-253
-
-
Hemani, G.1
Shakhbazov, K.2
Westra, H.J.3
Esko, T.4
Henders, A.K.5
McRae, A.F.6
Yang, J.7
Gibson, G.8
Martin, N.G.9
Metspalu, A.10
|