Gremlin-1 inhibits macrophage migration inhibitory factor-dependent monocyte function and survival

International Journal of Cardiology

Volumn 176, Issue 3, 2014, Pages 923-929

  Müller, Iris I ^a   Chatterjee, Madhumita ^a   Schneider, Martina ^a   Borst, Oliver ^a   Seizer, Peter ^a   Schönberger, Tanja ^a   Vogel, Sebastian ^a   Müller, Karin A L ^a   Geisler, Tobias ^a   Lang, Florian ^a   Langer, Harald ^a   Gawaz, Meinrad ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Apoptosis; Gremlin 1; MIF; Migration; Monocyte

Indexed keywords

GREM1 PROTEIN, HUMAN; MACROPHAGE MIGRATION INHIBITION FACTOR; SIGNAL PEPTIDE;

129 MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CELL LINE; CELL MOTION; CELL SURVIVAL; DRUG EFFECTS; HUMAN; KNOCKOUT MOUSE; MALE; MONOCYTE; MOUSE; PHYSIOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; CELL LINE; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES;

EID: 84908208213     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.08.051     Document Type: Article

References (29)

1. P. Libby, P.M. Ridker, and G.K. Hansson Progress and challenges in translating the biology of atherosclerosis Nature 473 2011 317 325
2. J. Bernhagen, R. Krohn, and H. Lue MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment Nat Med 13 2007 587 596
3. C. Weber, S. Kraemer, and M. Drechsler Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment Proc Natl Acad Sci U S A 105 2008 16278 16283
4. C. Weber, A. Zernecke, and P. Libby The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models Nat Rev Immunol 8 2008 802 815
5. Y.Z. Kong, X. Yu, and J.J. Tang Macrophage migration inhibitory factor induces MMP-9 expression: implications for destabilization of human atherosclerotic plaques Atherosclerosis 178 2005 207 215
6. S.G. Lin, X.Y. Yu, and Y.X. Chen De novo expression of macrophage migration inhibitory factor in atherogenesis in rabbits Circ Res 87 2000 1202 1208
7. A. Schober, J. Bernhagen, and M. Thiele Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice Circulation 109 2004 380 385
8. I.I. Muller, K.A. Muller, and H. Schonleber Macrophage migration inhibitory factor is enhanced in acute coronary syndromes and is associated with the inflammatory response PLoS One 7 2012 e38376
9. -/- mice J Biol Chem 288 2013 31635 31645
10. B. Chen, D.G. Blair, and S. Plisov Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis J Immunol 173 2004 5914 5917
11. P. Chiodelli, S. Mitola, C. Ravelli, P. Oreste, M. Rusnati, and M. Presta Heparan sulfate proteoglycans mediate the angiogenic activity of the vascular endothelial growth factor receptor-2 agonist gremlin Arterioscler Thromb Vasc Biol 31 2011 e116 e127
12. S. Diecke, A. Quiroga-Negreira, T. Redmer, and D. Besser FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells Cells Tissues Organs 188 2008 52 61
13. H. Namkoong, S.M. Shin, and H.K. Kim The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein BMC Cancer 6 2006 74
14. J.B. Sneddon, H.H. Zhen, and K. Montgomery Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation Proc Natl Acad Sci U S A 103 2006 14842 14847
15. R. Schmidt, A. Bultmann, and M. Ungerer Extracellular matrix metalloproteinase inducer regulates matrix metalloproteinase activity in cardiovascular cells: implications in acute myocardial infarction Circulation 113 2006 834 841
16. K. Stellos, H. Langer, and S. Gnerlich Junctional adhesion molecule A expressed on human CD34 + cells promotes adhesion on vascular wall and differentiation into endothelial progenitor cells Arterioscler Thromb Vasc Biol 30 2010 1127 1136
17. K. Stellos, H. Langer, and K. Daub Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34 + cells to endothelial progenitor cells Circulation 117 2008 206 215
18. R. Colognato, J.R. Slupsky, M. Jendrach, L. Burysek, T. Syrovets, and T. Simmet Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells Blood 102 2003 2645 2652
19. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
20. S. Massberg, M. Gawaz, and S. Gruner A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo J Exp Med 197 2003 41 49
21. S. Massberg, I. Konrad, and A. Bultmann Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo FASEB J 18 2004 397 399
22. S. Massberg, I. Konrad, and K. Schurzinger Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo J Exp Med 203 2006 1221 1233
23. K. Ley, Y.I. Miller, and C.C. Hedrick Monocyte and macrophage dynamics during atherogenesis Arterioscler Thromb Vasc Biol 31 2011 1506 1516
24. -/- mice Am J Pathol 177 2010 493 500
25. H. Lue, M. Thiele, and J. Franz Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity Oncogene 26 2007 5046 5059
26. O. Michos, A. Goncalves, and J. Lopez-Rios Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis Development 134 2007 2397 2405
27. S. Mitola, C. Ravelli, and E. Moroni Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2 Blood 116 2010 3677 3680
28. W. Shi, J. Zhao, K.D. Anderson, and D. Warburton Gremlin negatively modulates BMP-4 induction of embryonic mouse lung branching morphogenesis Am J Physiol Lung Cell Mol Physiol 280 2001 L1030 L1039
29. L.Z. Topol, B. Bardot, and Q. Zhang Biosynthesis, post-translation modification, and functional characterization of Drm/Gremlin J Biol Chem 275 2000 8785 8793