-
1
-
-
0031969264
-
Angiogenesis and tumor metastasis
-
Zetter BR. Angiogenesis and tumor metastasis. Annu Rev Med. 1998;49:407-424.
-
(1998)
Annu Rev Med.
, vol.49
, pp. 407-424
-
-
Zetter, B.R.1
-
2
-
-
77949906193
-
Tumor angiogenesis and novel antiangiogenic strategies
-
Gordon MS, Mendelson DS, Kato G. Tumor angiogenesis and novel antiangiogenic strategies. Int J Cancer. 2010;126(8):1777-1787.
-
(2010)
Int J Cancer.
, vol.126
, Issue.8
, pp. 1777-1787
-
-
Gordon, M.S.1
Mendelson, D.S.2
Kato, G.3
-
3
-
-
84861098484
-
Pazopanib for metastatic soft-tissue sarcoma (PALETTE): A randomised, double-blind, placebo-controlled phase 3 trial
-
van der Graaf WT, Blay JY, Chawla SP, et al; EORTC Soft Tissue and Bone Sarcoma Group; PALETTE study group. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2012;379(9829):1879-1886.
-
(2012)
Lancet.
, vol.379
, Issue.9829
, pp. 1879-1886
-
-
van der Graaf, W.T.1
Blay, J.Y.2
Chawla, S.P.3
-
4
-
-
84890571003
-
Cabozantinib in progressive medullary thyroid cancer
-
Elisei R, Schlumberger MJ, Müller SP, et al. Cabozantinib in progressive medullary thyroid cancer. J Clin Oncol. 2013;31(29):3639-3646.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.29
, pp. 3639-3646
-
-
Elisei, R.1
Schlumberger, M.J.2
Müller, S.P.3
-
5
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM, et al; TARGET Study Group. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med. 2007;356(2):125-134.
-
(2007)
N Engl J Med.
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
-
6
-
-
79851482955
-
Sunitinib malate for the treatment of pancreatic neuroendocrine tumors
-
Raymond E, Dahan L, Raoul JL, et al. Sunitinib malate for the treatment of pancreatic neuroendocrine tumors. N Engl J Med. 2011;364(6): 501-513.
-
(2011)
N Engl J Med.
, vol.364
, Issue.6
, pp. 501-513
-
-
Raymond, E.1
Dahan, L.2
Raoul, J.L.3
-
7
-
-
70350002279
-
Adverse effects of anticancer agents that target the VEGF pathway
-
Chen HX, Cleck JN. Adverse effects of anticancer agents that target the VEGF pathway. Nat Rev Clin Oncol. 2009;6(8):465-477.
-
(2009)
Nat Rev Clin Oncol.
, vol.6
, Issue.8
, pp. 465-477
-
-
Chen, H.X.1
Cleck, J.N.2
-
8
-
-
84865439183
-
Treatment-related mortality with vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy in patients with advanced solid tumors: A meta-analysis
-
Sivendran S, Liu Z, Portas LJ Jr, et al. Treatment-related mortality with vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy in patients with advanced solid tumors: a meta-analysis. Cancer Treat Rev. 2012;38(7):919-925.
-
(2012)
Cancer Treat Rev.
, vol.38
, Issue.7
, pp. 919-925
-
-
Sivendran, S.1
Liu, Z.2
Portas, L.J.3
-
9
-
-
84858848994
-
Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors
-
Schutz FA, Je Y, Richards CJ, Choueiri TK. Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. J Clin Oncol. 2012;30(8): 871-877.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.8
, pp. 871-877
-
-
Schutz, F.A.1
Je, Y.2
Richards, C.J.3
Choueiri, T.K.4
-
11
-
-
84897018646
-
Randomized, placebo-controlled, phase III trial of sunitinib plus prednisone versus prednisone alone in progressive, metastatic, castration-resistant prostate cancer
-
Michaelson MD, Oudard S, Ou YC, et al. Randomized, placebo-controlled, phase III trial of sunitinib plus prednisone versus prednisone alone in progressive, metastatic, castration-resistant prostate cancer. J Clin Oncol. 2014;32(2):76-82.
-
(2014)
J Clin Oncol.
, vol.32
, Issue.2
, pp. 76-82
-
-
Michaelson, M.D.1
Oudard, S.2
Ou, Y.C.3
-
12
-
-
84877098937
-
Sorafenib in combination with oxaliplatin, leucovorin, and fluorouracil (modified FOLFOX6) as first-line treatment of metastatic colorectal cancer: The RESPECT trial
-
Tabernero J, Garcia-Carbonero R, Cassidy J, et al. Sorafenib in combination with oxaliplatin, leucovorin, and fluorouracil (modified FOLFOX6) as first-line treatment of metastatic colorectal cancer: the RESPECT trial. Clin Cancer Res. 2013;19(9):2541-2550.
-
(2013)
Clin Cancer Res.
, vol.19
, Issue.9
, pp. 2541-2550
-
-
Tabernero, J.1
Garcia-Carbonero, R.2
Cassidy, J.3
-
13
-
-
84873346707
-
Phase III trial of carboplatin and paclitaxel with or without sorafenib in metastatic melanoma
-
Flaherty KT, Lee SJ, Zhao F, et al. Phase III trial of carboplatin and paclitaxel with or without sorafenib in metastatic melanoma. J Clin Oncol. 2013;31(3):373-379.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.3
, pp. 373-379
-
-
Flaherty, K.T.1
Lee, S.J.2
Zhao, F.3
-
14
-
-
84876089340
-
Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: A randomized, phase III trial
-
Carrato A, Swieboda-Sadlej A, Staszewska-Skurczynska M, et al. Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: a randomized, phase III trial. J Clin Oncol. 2013;31(10):1341-1347.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.10
, pp. 1341-1347
-
-
Carrato, A.1
Swieboda-Sadlej, A.2
Staszewska-Skurczynska, M.3
-
15
-
-
84865552505
-
Vandetanib in locally advanced or metastatic differentiated thyroid cancer: A randomised, double-blind, phase 2 trial
-
Leboulleux S, Bastholt L, Krause T, et al. Vandetanib in locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 2 trial. Lancet Oncol. 2012;13(9):897-905.
-
(2012)
Lancet Oncol.
, vol.13
, Issue.9
, pp. 897-905
-
-
Leboulleux, S.1
Bastholt, L.2
Krause, T.3
-
16
-
-
84862988257
-
Sorafenib in combination with capecitabine: An oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer
-
Baselga J, Segalla JG, Roché H, et al. Sorafenib in combination with capecitabine: an oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer. J Clin Oncol. 2012;30(13): 1484-1491.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.13
, pp. 1484-1491
-
-
Baselga, J.1
Segalla, J.G.2
Roché, H.3
-
17
-
-
84868107516
-
BAYPAN study: A double-blind phase III randomized trial comparing gemcitabine plus sorafenib and gemcitabine plus placebo in patients with advanced pancreatic cancer
-
Gonçalves A, Gilabert M, François E, et al. BAYPAN study: a double-blind phase III randomized trial comparing gemcitabine plus sorafenib and gemcitabine plus placebo in patients with advanced pancreatic cancer. Ann Oncol. 2012;23(11):2799-2805.
-
(2012)
Ann Oncol.
, vol.23
, Issue.11
, pp. 2799-2805
-
-
Gonçalves, A.1
Gilabert, M.2
François, E.3
-
18
-
-
84872110165
-
A double-blind, randomised, placebo-controlled, phase 2b study evaluating sorafenib in combination with paclitaxel as a first-line therapy in patients with HER2-negative advanced breast cancer
-
Gradishar WJ, Kaklamani V, Sahoo TP, et al. A double-blind, randomised, placebo-controlled, phase 2b study evaluating sorafenib in combination with paclitaxel as a first-line therapy in patients with HER2-negative advanced breast cancer. Eur J Cancer. 2013;49(2):312-322.
-
(2013)
Eur J Cancer.
, vol.49
, Issue.2
, pp. 312-322
-
-
Gradishar, W.J.1
Kaklamani, V.2
Sahoo, T.P.3
-
19
-
-
84879112772
-
A randomized phase II trial of maintenance therapy with Sorafenib in front-line ovarian carcinoma
-
Herzog TJ, Scambia G, Kim BG, et al. A randomized phase II trial of maintenance therapy with Sorafenib in front-line ovarian carcinoma. Gynecol Oncol. 2013;130(1):25-30.
-
(2013)
Gynecol Oncol.
, vol.130
, Issue.1
, pp. 25-30
-
-
Herzog, T.J.1
Scambia, G.2
Kim, B.G.3
-
20
-
-
84899679988
-
Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma
-
Hutson TE, Escudier B, Esteban E, et al. Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma. J Clin Oncol. 2014;32(8): 760-767.
-
(2014)
J Clin Oncol.
, vol.32
, Issue.8
, pp. 760-767
-
-
Hutson, T.E.1
Escudier, B.2
Esteban, E.3
-
21
-
-
84865721505
-
Phase III, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer
-
Paz-Ares LG, Biesma B, Heigener D, et al; NSCLC [non-small-cell lung cancer] Research Experience Utilizing Sorafenib (NExUS) Investigators Study Group. Phase III, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer. J Clin Oncol. 2012;30(25):3084-3092.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.25
, pp. 3084-3092
-
-
Paz-Ares, L.G.1
Biesma, B.2
Heigener, D.3
-
22
-
-
84860625265
-
First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: Results of a prospective, randomized phase III study
-
Bergh J, Bondarenko IM, Lichinitser MR, et al. First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: results of a prospective, randomized phase III study. J Clin Oncol. 2012;30(9):921-929.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.9
, pp. 921-929
-
-
Bergh, J.1
Bondarenko, I.M.2
Lichinitser, M.R.3
-
23
-
-
84861786753
-
Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure
-
Demetri GD, Garrett CR, Schöffski P, et al. Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure. Clin Cancer Res. 2012;18(11):3170-3179.
-
(2012)
Clin Cancer Res.
, vol.18
, Issue.11
, pp. 3170-3179
-
-
Demetri, G.D.1
Garrett, C.R.2
Schöffski, P.3
-
24
-
-
79959286206
-
Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer
-
Rugo HS, Stopeck AT, Joy AA, et al. Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer. J Clin Oncol. 2011;29(18):2459-2465.
-
(2011)
J Clin Oncol.
, vol.29
, Issue.18
, pp. 2459-2465
-
-
Rugo, H.S.1
Stopeck, A.T.2
Joy, A.A.3
-
25
-
-
84872892692
-
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): An international, multicentre, randomised, placebo-controlled, phase 3 trial
-
Demetri GD, Reichardt P, Kang YK, et al; GRID study investigators. Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet. 2013;381(9863):295-302.
-
(2013)
Lancet.
, vol.381
, Issue.9863
, pp. 295-302
-
-
Demetri, G.D.1
Reichardt, P.2
Kang, Y.K.3
-
26
-
-
0029914622
-
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
-
Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996;17(1):1-12.
-
(1996)
Control Clin Trials.
, vol.17
, Issue.1
, pp. 1-12
-
-
Jadad, A.R.1
Moore, R.A.2
Carroll, D.3
-
27
-
-
69149107165
-
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
-
Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151(4):264-269, W64.
-
(2009)
Ann Intern Med.
, vol.151
, Issue.4
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
28
-
-
14544284502
-
Risks and benefits of phase 1 oncology trials, 1991 through 2002
-
Horstmann E, McCabe MS, Grochow L, et al. Risks and benefits of phase 1 oncology trials, 1991 through 2002. N Engl J Med. 2005;352(9): 895-904.
-
(2005)
N Engl J Med.
, vol.352
, Issue.9
, pp. 895-904
-
-
Horstmann, E.1
McCabe, M.S.2
Grochow, L.3
-
29
-
-
84887617202
-
A randomized, phase II study of vandetanib maintenance for advanced or metastatic non-small-cell lung cancer following first-line platinum-doublet chemotherapy
-
Ahn JS, Lee KH, Sun JM, et al. A randomized, phase II study of vandetanib maintenance for advanced or metastatic non-small-cell lung cancer following first-line platinum-doublet chemotherapy. Lung Cancer. 2013;82(3):455-460.
-
(2013)
Lung Cancer.
, vol.82
, Issue.3
, pp. 455-460
-
-
Ahn, J.S.1
Lee, K.H.2
Sun, J.M.3
-
30
-
-
84883360843
-
A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC)
-
Groen HJ, Socinski MA, Grossi F, et al. A randomized, double-blind, phase II study of erlotinib with or without sunitinib for the second-line treatment of metastatic non-small-cell lung cancer (NSCLC). Ann Oncol. 2013;24(9):2382-2389.
-
(2013)
Ann Oncol.
, vol.24
, Issue.9
, pp. 2382-2389
-
-
Groen, H.J.1
Socinski, M.A.2
Grossi, F.3
-
31
-
-
84893413347
-
CALGB 30704 (Alliance): A randomized phase II study to assess the efficacy of pemetrexed or sunitinib or pemetrexed plus sunitinib in the second-line treatment of advanced non-small-cell lung cancer
-
Heist RS, Wang X, Hodgson L, et al; Alliance for Clinical Trials in Oncology. CALGB 30704 (Alliance): A randomized phase II study to assess the efficacy of pemetrexed or sunitinib or pemetrexed plus sunitinib in the second-line treatment of advanced non-small-cell lung cancer. J Thorac Oncol. 2014;9(2):214-221.
-
(2014)
J Thorac Oncol.
, vol.9
, Issue.2
, pp. 214-221
-
-
Heist, R.S.1
Wang, X.2
Hodgson, L.3
Alliance for Clinical Trials in Oncology4
-
32
-
-
34948838898
-
Randomized, placebo-controlled phase II study of vandetanib plus docetaxel in previously treated non small-cell lung cancer
-
Heymach JV, Johnson BE, Prager D, et al. Randomized, placebo-controlled phase II study of vandetanib plus docetaxel in previously treated non small-cell lung cancer. J Clin Oncol. 2007;25(27): 4270-4277.
-
(2007)
J Clin Oncol.
, vol.25
, Issue.27
, pp. 4270-4277
-
-
Heymach, J.V.1
Johnson, B.E.2
Prager, D.3
-
33
-
-
56749102822
-
Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer
-
Heymach JV, Paz-Ares L, De Braud F, et al. Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer. J Clin Oncol. 2008;26(33):5407-5415.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.33
, pp. 5407-5415
-
-
Heymach, J.V.1
Paz-Ares, L.2
De Braud, F.3
-
34
-
-
77951639655
-
Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer
-
Scagliotti G, Novello S, von Pawel J, et al. Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer. J Clin Oncol. 2010;28(11):1835-1842.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.11
, pp. 1835-1842
-
-
Scagliotti, G.1
Novello, S.2
von Pawel, J.3
-
35
-
-
84863936062
-
Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non-small-cell lung cancer: A phase III trial
-
Scagliotti GV, Krzakowski M, Szczesna A, et al. Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non-small-cell lung cancer: a phase III trial. J Clin Oncol. 2012;30(17):2070-2078.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.17
, pp. 2070-2078
-
-
Scagliotti, G.V.1
Krzakowski, M.2
Szczesna, A.3
-
36
-
-
77951296573
-
Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer
-
Barrios CH, Liu MC, Lee SC, et al. Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer. Breast Cancer Res Treat. 2010;121(1):121-131.
-
(2010)
Breast Cancer Res Treat.
, vol.121
, Issue.1
, pp. 121-131
-
-
Barrios, C.H.1
Liu, M.C.2
Lee, S.C.3
-
37
-
-
84861040218
-
Vandetanib with docetaxel as second-line treatment for advanced breast cancer: A double-blind, placebo-controlled, randomized Phase II study
-
Boér K, Láng I, Llombart-Cussac A, et al. Vandetanib with docetaxel as second-line treatment for advanced breast cancer: a double-blind, placebo-controlled, randomized Phase II study. Invest New Drugs. 2012;30(2):681-687.
-
(2012)
Invest New Drugs.
, vol.30
, Issue.2
, pp. 681-687
-
-
Boér, K.1
Láng, I.2
Llombart-Cussac, A.3
-
38
-
-
84879338637
-
A randomized and open-label trial evaluating the addition of pazopanib to lapatinib as first-line therapy in patients with HER2-positive advanced breast cancer
-
Johnston SR, Gómez H, Stemmer SM, et al. A randomized and open-label trial evaluating the addition of pazopanib to lapatinib as first-line therapy in patients with HER2-positive advanced breast cancer. Breast Cancer Res Treat. 2013;137(3):755-766.
-
(2013)
Breast Cancer Res Treat.
, vol.137
, Issue.3
, pp. 755-766
-
-
Johnston, S.R.1
Gómez, H.2
Stemmer, S.M.3
-
39
-
-
84878059586
-
Sorafenib or placebo with either gemcitabine or capecitabine in patients with HER-2-negative advanced breast cancer that progressed during or after bevacizumab
-
Schwartzberg LS, Tauer KW, Hermann RC, et al. Sorafenib or placebo with either gemcitabine or capecitabine in patients with HER-2-negative advanced breast cancer that progressed during or after bevacizumab. Clin Cancer Res. 2013;19(10):2745-2754.
-
(2013)
Clin Cancer Res.
, vol.19
, Issue.10
, pp. 2745-2754
-
-
Schwartzberg, L.S.1
Tauer, K.W.2
Hermann, R.C.3
-
40
-
-
68949145218
-
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol. 2009;27(22):3584-3590.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.22
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
41
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol. 2010;28(6):1061-1068.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.6
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
42
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol. 2009;10(1):25-34.
-
(2009)
Lancet Oncol.
, vol.10
, Issue.1
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
-
43
-
-
79960805810
-
Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma
-
Kudo M, Imanaka K, Chida N, et al. Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma. Eur J Cancer. 2011;47(14):2117-2127.
-
(2011)
Eur J Cancer.
, vol.47
, Issue.14
, pp. 2117-2127
-
-
Kudo, M.1
Imanaka, K.2
Chida, N.3
-
44
-
-
84886793895
-
Maintenance sunitinib or observation in metastatic pancreatic adenocarcinoma: A phase II randomised trial
-
Reni M, Cereda S, Milella M, et al. Maintenance sunitinib or observation in metastatic pancreatic adenocarcinoma: a phase II randomised trial. Eur J Cancer. 2013;49(17):3609-3615.
-
(2013)
Eur J Cancer.
, vol.49
, Issue.17
, pp. 3609-3615
-
-
Reni, M.1
Cereda, S.2
Milella, M.3
-
45
-
-
66249113517
-
A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer
-
Horti J, Widmark A, Stenzl A, et al. A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer. Cancer Biother Radiopharm. 2009;24(2):175-180.
-
(2009)
Cancer Biother Radiopharm.
, vol.24
, Issue.2
, pp. 175-180
-
-
Horti, J.1
Widmark, A.2
Stenzl, A.3
-
46
-
-
67649909568
-
Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma
-
Hauschild A, Agarwala SS, Trefzer U, et al. Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma. J Clin Oncol. 2009;27(17):2823-2830.
-
(2009)
J Clin Oncol.
, vol.27
, Issue.17
, pp. 2823-2830
-
-
Hauschild, A.1
Agarwala, S.S.2
Trefzer, U.3
-
47
-
-
43749110700
-
Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: A report from the 11715 Study Group
-
McDermott DF, Sosman JA, Gonzalez R, et al. Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group. J Clin Oncol. 2008;26(13):2178-2185.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.13
, pp. 2178-2185
-
-
McDermott, D.F.1
Sosman, J.A.2
Gonzalez, R.3
-
48
-
-
34948844052
-
Phase II study of vandetanib or placebo in small-cell lung cancer patients after complete or partial response to induction chemotherapy with or without radiation therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20
-
Arnold AM, Seymour L, Smylie M, et al; National Cancer Institute of Canada Clinical Trials Group Study BR.20. Phase II study of vandetanib or placebo in small-cell lung cancer patients after complete or partial response to induction chemotherapy with or without radiation therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20. J Clin Oncol. 2007;25(27):4278-4284.
-
(2007)
J Clin Oncol.
, vol.25
, Issue.27
, pp. 4278-4284
-
-
Arnold, A.M.1
Seymour, L.2
Smylie, M.3
National Cancer Institute of Canada4
-
49
-
-
84856851592
-
Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer
-
Choueiri TK, Ross RW, Jacobus S, et al. Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer. J Clin Oncol. 2012;30(5):507-512.
-
(2012)
J Clin Oncol.
, vol.30
, Issue.5
, pp. 507-512
-
-
Choueiri, T.K.1
Ross, R.W.2
Jacobus, S.3
-
50
-
-
84880049211
-
A randomized phase II study of docetaxel with or without vandetanib in recurrent or metastatic squamous cell carcinoma of head and neck (SCCHN)
-
Limaye S, Riley S, Zhao S, et al. A randomized phase II study of docetaxel with or without vandetanib in recurrent or metastatic squamous cell carcinoma of head and neck (SCCHN). Oral Oncol. 2013;49(8): 835-841.
-
(2013)
Oral Oncol.
, vol.49
, Issue.8
, pp. 835-841
-
-
Limaye, S.1
Riley, S.2
Zhao, S.3
-
51
-
-
84922337274
-
Risk of treatment-related mortality with sorafenib in patients with cancer
-
Zhang XJ, Zhang TY, Yu FF, et al. Risk of treatment-related mortality with sorafenib in patients with cancer. Asian Pac J Cancer Prev. 2013;14(11):6681-6686.
-
(2013)
Asian Pac J Cancer Prev.
, vol.14
, Issue.11
, pp. 6681-6686
-
-
Zhang, X.J.1
Zhang, T.Y.2
Yu, F.F.3
-
52
-
-
84888793629
-
Incidence and risk of hemorrhagic events with vascular endothelial growth factor receptor tyrosine-kinase inhibitors: An up-to-date meta-analysis of 27 randomized controlled trials
-
Qi WX, Tang LN, Sun YJ, et al. Incidence and risk of hemorrhagic events with vascular endothelial growth factor receptor tyrosine-kinase inhibitors: an up-to-date meta-analysis of 27 randomized controlled trials. Ann Oncol. 2013;24(12):2943-2952.
-
(2013)
Ann Oncol.
, vol.24
, Issue.12
, pp. 2943-2952
-
-
Qi, W.X.1
Tang, L.N.2
Sun, Y.J.3
-
53
-
-
84898408415
-
Safety and efficacy of addition of VEGFR and EGFR-family oral small-molecule tyrosine kinase inhibitors to cytotoxic chemotherapy in solid cancers: A systematic review and meta-analysis of randomized controlled trials
-
Funakoshi T, Latif A, Galsky MD. Safety and efficacy of addition of VEGFR and EGFR-family oral small-molecule tyrosine kinase inhibitors to cytotoxic chemotherapy in solid cancers: a systematic review and meta-analysis of randomized controlled trials. Cancer Treat Rev. 2014;40(5):636-647.
-
(2014)
Cancer Treat Rev.
, vol.40
, Issue.5
, pp. 636-647
-
-
Funakoshi, T.1
Latif, A.2
Galsky, M.D.3
-
54
-
-
55949123335
-
Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma
-
Schmidinger M, Zielinski CC, Vogl UM, et al. Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol. 2008;26(32):5204-5212.
-
(2008)
J Clin Oncol.
, vol.26
, Issue.32
, pp. 5204-5212
-
-
Schmidinger, M.1
Zielinski, C.C.2
Vogl, U.M.3
-
55
-
-
77952310126
-
Risk of arterial thromboembolic events with sunitinib and sorafenib: A systematic review and meta-analysis of clinical trials
-
Choueiri TK, Schutz FA, Je Y, Rosenberg JE, Bellmunt J. Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. J Clin Oncol. 2010;28(13): 2280-2285.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.13
, pp. 2280-2285
-
-
Choueiri, T.K.1
Schutz, F.A.2
Je, Y.3
Rosenberg, J.E.4
Bellmunt, J.5
-
56
-
-
40349103260
-
Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia
-
Bennett CL, Silver SM, Djulbegovic B, et al. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA. 2008;299(8):914-924.
-
(2008)
JAMA.
, vol.299
, Issue.8
, pp. 914-924
-
-
Bennett, C.L.1
Silver, S.M.2
Djulbegovic, B.3
|