Altered Hemodynamics and Hyperuricemia Accompany an Elevated sFlt-1/PlGF Ratio Before the Onset of Early Severe Preeclampsia

Journal of Obstetrics and Gynaecology Canada

Volumn 36, Issue 8, 2014, Pages 692-700

  Doherty, Anne ^a   Carvalho, Jose C A ^a,b   Drewlo, Sascha ^b,c   EL Khuffash, Afif ^a   Downey, Kristi ^a   Dodds, Madelaine ^b   Kingdom, John ^b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Bioreactance; Early severe preeclampsia; NICOM; PlGF; Sflt 1; Uric acid; Vascular resistance

Indexed keywords

BIOLOGICAL MARKER; PLACENTAL GROWTH FACTOR; PLACENTAL LIKE GROWTH FACTOR; UNCLASSIFIED DRUG; URIC ACID; VASCULOTROPIN RECEPTOR 1; PLACENTA PROTEIN;

ADULT; ANALYTICAL PARAMETERS; ARTICLE; BIRTH WEIGHT; BLOOD SAMPLING; CARDIOVASCULAR MONITORING DEVICE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE COURSE; FEMALE; GESTATIONAL AGE; HEART OUTPUT; HEART RATE; HEMODYNAMIC MONITORING; HEMODYNAMICS; HIGH RISK PATIENT; HUMAN; HYPERURICEMIA; INTRAUTERINE GROWTH RETARDATION; MATERNAL SERUM SCREENING TEST; NON INVASIVE MEASUREMENT; PREECLAMPSIA; RISK FACTOR; SERUM SOLUBLE FMS LIKE TYROSINE KINASE TO PLACENTA LIKE GROWTH FACTOR RATIO; SEVERE PREECLAMPSIA; SYSTOLIC BLOOD PRESSURE; URIC ACID BLOOD LEVEL; VASCULAR RESISTANCE; BIOREACTANCE; BLOOD; COHORT ANALYSIS; EARLY SEVERE PREECLAMPSIA; NICOM; PLGF; PREGNANCY; SFLT -1;

BIOREACTANCE; EARLY SEVERE PREECLAMPSIA; NICOM; PLGF; SFLT -1; URIC ACID; VASCULAR RESISTANCE;

BIOLOGICAL MARKERS; COHORT STUDIES; FEMALE; HEMODYNAMICS; HUMANS; HYPERURICEMIA; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84908176743     PISSN: 17012163     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1701-2163(15)30511-9     Document Type: Article

References (30)

1. Sibai B.M., Gordon T., Thom E., Caritis S.N., Klebanoff M., McNellis D., et al. Risk factors for preeclampsia in healthy nulliparous women: a prospective multicenter study. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. Am J Obstet Gynecol 1995, 172(2 Pt 1):642-648.
2. Hypertension in pregnancy Report of the American College of Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy. Obstet Gynecol 2013, 122(5):1122-1131.
3. Kucukgoz G.U., Ozgunen F.T., Buyukkurt S., Guzel A.B., Urunsak I.F., Demir S.C., et al. Comparison of clinical and laboratory findings in early- and late-onset preeclampsia. J Matern Fetal Neonatal Med 2013, 26(12):1228-1233.
4. Raymond D., Peterson E. A critical review of early-onset and late-onset preeclampsia. Obstet Gynecol Surv 2011, 66(8):497-506.
5. Valensise H., Vasapollo B., Gagliardi G., Novelli G.P. Early and late preeclampsia: two different maternal hemodynamic states in the latent phase of the disease. Hypertension 2008, 52(5):873-880.
6. Walker M.G., Fitzgerald B., Keating S., Ray J.G., Windrim R., Kingdom J.C. Sex-specific basis of severe placental dysfunction leading to extreme preterm delivery. Placenta 2012, 33(7):568-571.
7. Vasapollo B., Novelli G.P., Valensise H. Total vascular resistance and left ventricular morphology as screening tools for complications in pregnancy. Hypertension 2008, 51(4):1020-1026.
8. Thangaratinam S., Ismail K.M., Sharp S., Coomarasamy A., Khan K.S. Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review. BJOG 2006, 113(4):369-378.
9. Noori M., Donald A.E., Angelakopoulou A., Hingorani A.D., Williams D.J. Prospective study of placental angiogenic factors and maternal vascular function before and after preeclampsia and gestational hypertension. Circulation 2010, 122(5):478-487.
10. Toal M., Keating S., Machin G., Dodd J., Adamson S.L., Windrim R.C., et al. Determinants of adverse perinatal outcome in high-risk women with abnormal uterine artery Doppler images. Am J Obstet Gynecol 2008, 198(3):330-337.
11. Proctor L.K., Toal M., Keating S., Chitayat D., Okun N., Windrim R.C., et al. Placental size and the prediction of severe early-onset intrauterine growth restriction in women with low pregnancy-associated plasma protein-A. Ultrasound Obstet Gynecol 2009, 34(3):274-282.
12. Porat S., Fitzgerald B., Wright E., Keating S., Kingdom J.C. Placental hyperinflation and the risk of adverse perinatal outcome. Ultrasound Obstet Gynecol 2013, 42(3):315-321.
13. Squara P., Denjean D., Estagnasie P., Brusset A., Dib J.C., Dubois C. Noninvasive cardiac output monitoring (NICOM): a clinical validation. Intensive Care Med 2007, 33(7):1191-1194.
14. Raval N.Y., Squara P., Cleman M., Yalamanchili K., Winklmaier M., Burkhoff D. Multicenter evaluation of noninvasive cardiac output measurement by bioreactance technique. J Clin Monit Comput 2008, 22(2):113-119.
15. American College of Obstetricians and Gynaecologists Diagnosis and management of preeclampsia and eclampsia. ACOG practice bulletin, no. 33, January 2002. Obstet Gynecol 2002, 99(1):159-167.
16. Ray J.G., Sgro M., Mamdani M.M., Glazier R.H., Bocking A., Hilliard R., et al. Birth weight curves tailored to maternal world region. J Obstet Gynaecol Can 2012, 34(2):159-171.
17. North R.A., McCowan L.M., Dekker G.A., Poston L., Chan E.H., Stewart A.W., et al. Clinical risk prediction for pre-eclampsia in nulliparous women: development of model in international prospective cohort. BMJ 2011, 342:d1875.
18. Bamfo J.E., Kametas N.A., Turan O., Khaw A., Nicolaides K.H. Maternal cardiac function in fetal growth restriction. BJOG 2006, 113(7):784-791.
19. Easterling T.R., Brateng D., Schmucker B., Brown Z., Millard S.P. Prevention of preeclampsia: a randomized trial of atenolol in hyperdynamic patients before onset of hypertension. Obstet Gynecol 1999, 93(5 Pt 1):725-733.
20. Dennis A., Arhanghelschi I., Simmons S., Royse C. Prospective observational study of serial cardiac output by transthoracic echocardiography in healthy pregnant women undergoing elective caesarean delivery. Int J Obstet Anesth 2010, 19(2):142-148.
21. Khaw A., Kametas N.A., Turan O.M., Bamfo J.E., Nicolaides K.H. Maternal cardiac function and uterine artery Doppler at 11-14 weeks in the prediction of pre-eclampsia in nulliparous women. BJOG 2008, 115(3):369-376.
22. Bamfo J.E., Kametas N.A., Chambers J.B., Nicolaides K.H. Maternal cardiac function in normotensive and pre-eclamptic intrauterine growth restriction. Ultrasound Obstet Gynecol 2008, 32(5):682-686.
23. Melchiorre K., Sutherland G.R., Liberati M., Thilaganathan B. Maternal cardiovascular impairment in pregnancies complicated by severe fetal growth restriction. Hypertension 2012, 60:437-443.
24. Melchiorre K., Thilaganathan B. Maternal cardiac function in preeclampsia. Curr Opin Obstet Gynecol 2011, 23:440-447.
25. Rana S., Powe C.E., Salahuddin S., Verlohren S., Perschel F.H., Levine R.J., et al. Angiogenic factors and the risk of adverse outcomes in women with suspected preeclampsia. Circulation 2012, 125(7):911-919.
26. Taylor R.N., Grimwood J., Taylor R.S., McMaster M.T., Fisher S.J., North R.A. Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies. Am J Obstet Gynecol 2003, 188(1):177-182.
27. Osol G., Celia G., Gokina N., Barron C., Chien E., Mandala M., et al. Placental growth factor is a potent vasodilator of rat and human resistance arteries. Am J Physiol Heart Circ Physiol 2008, 294(3):H1381-H1387.
28. Levine R.J., Maynard S.E., Qian C., Lim K.H., England L.J., Yu K.F., et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004, 350(7):672-683.
29. Bellomo G., Venanzi S., Saronio P., Verdura C., Narducci P.L. Prognostic significance of serum uric acid in women with gestational hypertension. Hypertension 2011, 58(4):704-708.
30. Roberts J.M., Bodnar L.M., Lain K.Y., Hubel C.A., Markovic N., Ness R.B., et al. Uric acid is as important as proteinuria in identifying fetal risk in women with gestational hypertension. Hypertension 2005, 46(6):1263-1269.