Selection response to DNA testing for canine ceroid lipofuscinosis in Tibetan terriers

Veterinary Journal

Volumn 201, Issue 3, 2014, Pages 433-434

  Kluth, Susanne ^a   Eckardt, Judith ^a   Distl, Ottmar ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

ATP13A2; Canine ceroid lipofuscinosis; Selection; Tibetan terrier

Indexed keywords

DNA;

ARTICLE; ATP13A2 GENE; CANINE CEROID LIPOFUSCINOSIS; CONTROLLED STUDY; DNA DETERMINATION; DNA EXTRACTION; GENE; GENE FREQUENCY; GENE MUTATION; GENOTYPE; HETEROZYGOSITY; HETEROZYGOTE; HOMOZYGOSITY; LIPOFUSCINOSIS; MUTANT; NONHUMAN; TERRIER; ANIMAL; BLOOD; DOG; DOG DISEASE; GENETIC SELECTION; GENETICS; GERMANY; MUTATION; NEURONAL CEROID LIPOFUSCINOSIS; SPECIES DIFFERENCE;

ANIMALS; DNA; DOG DISEASES; DOGS; GERMANY; MUTATION; NEURONAL CEROID-LIPOFUSCINOSES; SELECTION, GENETIC; SPECIES SPECIFICITY;

EID: 84908174221     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2014.05.029     Document Type: Article

References (8)

1. Alroy J., Schelling S.H., Thalhammer J.G. Adult onset lysosomal storage disease in a Tibetan terrier: Clinical, morphological and biochemical studies. Acta Neuropathologica 1992, 84:658-663.
2. Clark, A.R., Brace, A.H., Sporre-Willes, R., Fleig, D., Fleig, H., 1995. Kynos Großer Hundeführer. Kynos Verlag, Mürlenbach, Eifel, Germany.
3. Farias F.H.G., Zeng R., Johnson G.S., Wininger F.A., Taylor J.F., Schnabel R.D., McKay S.D., Sanders D.N., Lohi H., Seppälä E.H., et al. A truncating mutation in ATP13A2 is responsible for adult-onset neuronal ceroid lipofuscinosis in Tibetan terriers. Neurobiology of Disease 2011, 42:468-474.
4. Jalanko A., Braulke T. Neuronal ceroid lipofuscinoses. Biochimica et Biophysica Acta 2009, 1793:697-709.
5. Jolly R.D., Palmer D.N., Studdert V.P., Sutton R.H., Kelly W.R., Koppang N., Dahme G., Hartley W.J., Patterson J.S., Riis R.C. Canine ceroid-lipofuscinoses: A review and classification. Journal of Small Animal Practice 1994, 35:299-306.
6. Ketteritzsch K., Hamann H., Brahm R., Grußendorf H., Rosenhagen C.U., Distl O. Genetic analysis of presumed inherited eye diseases in Tibetan terriers. The Veterinary Journal 2004, 168:151-159.
7. Riis R.C., Cummings J.F., Loew E.R. Tibetan terrier model of canine ceroid lipofuscinosis. American Journal of Medical Genetics 1992, 42:615-621.
8. Wöhlke A., Philipp U., Bock P., Beineke A., Lichtner P., Meitinger T., Distl O. A one base pair deletion in the canine ATP13A2 gene causes exon skipping and late-onset neuronal ceroid lipofuscinosis in the Tibetan terrier. PLoS Genetics 2011, 7:e1002304.