Frequency of a very rare 35delG mutation in two ethnic groups of Iranian populations

Iranian Journal of Public Health

Volumn 33, Issue 4, 2004, Pages 26-30

  Sasanfar, R ^a   Tolouei, A ^f   Hoseinipour, A ^a   Farhud, D D ^b   Dolati, M ^c   Rad, L Hoghooghi ^d   Zohour, M Montazer ^b   Ghadami, M ^a   Pour Jafari, H ^e   Chaleshtori, M Hashemzadeh ^b,d  

^a Ministry of Education and Training   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

^d SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e HAMADAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f NONE

Author keywords

Autosomal recessive non syndromic hearing loss; Connexin 26; Deafness; GJB2; Iran; Mutation

Indexed keywords

EID: 84908154905     PISSN: 22516085     EISSN: 22516093     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Baris I, Kilinc MO, Tolun A (2001). Frequency of the 35 delG mutation in the connexin 26 gene in Turkish hearingimpaired patients. Clin Genet, 60: 452-55.
2. Mueller RF, Nehammer A, Middleton A, Houseman M, Taylor GR, Bitner-Glindzciz, et al (1999). Congenital non-yndromal sesorineural hearing impairment due to connexin 26 gene mutations-molecular and audiological findings. Int J Ped Otorhinolaryngolo, 50: 3-13.
3. Rickard S, Kelsell DP, Sirimana T, Rajput K, MacArdle B, Bitner-Glindzciz M (2001). Recurrent mutations in the deafness gene GJB2 (connexin 26) in British Asian families. J Med Genet, 38: 530-33.
4. White TW (2000). Functional analysis of human CX26 mutations associated with deafness. Brain Research Reviews, 32: 181-83.
5. Murgia A, Orzan E, Polli R, Martella M, Vinanzi C, Leonardi E, Arslan E, Zacchello F (1999). CX26 deafness: mutation analysis and clinical variability. J Med Genet, 39: 829-32.
6. Hashemzadeh Chaleshtori M, Farhud DD, Taylor R, Hadavi V, Patton MA, Afzal AR (2002). Deafness-Associated Connexin 26 Gene (GJB2) Mutations in Iranian Population. Iranian J Publ Health, 31: 75-9.
7. Saroko Abe, Shin-ichi Usami, Hideichi Shinkawa, Philip M Kelley, William J Kimberling (2000). Prevalent connexin 26 gene (GJB2) mutations in Japanese. J Med Genet, 37: 41-43.
8. Brown KA, Janjua AH, Karbani G, Parry G, Noble A, Crock ford G, Bishop DT et al (1996). Linkage studies of non-syndromic recessive deafness (NSRD) in a family originating from the Mirpur region of Pakistan maps DFNBI centromeric to DI 13S175. Human Mol Genet, 5: 169-73.
9. M Hashemzadeh Chaleshtori, Doulati (2004). Two novel mutations and predominant 35delG mutations in the connexin 26 gene (GJB2) in Iranian population. Iranian J Publ Health, 33(2): 14-9.
10. Najmabadi H, Cucci RA, Sahebjam S, Kouchakian N, Farhadi M, Kahrizi K, Arzhangi S et al (2002). GJB2 Mutations in Iranians with Autosomal Recessive Non-syndromic Sensorineural Hearing Loss. Human Mut, Mutation in Brief#504 Online.