Body-composition predictors of mortality in women aged ≥75 y: Data from a large population-based cohort study with a 17-y follow-up

American Journal of Clinical Nutrition

Volumn 100, Issue 5, 2014, Pages 1352-1360

  Rolland, Yves ^a,b   Gallini, Adeline ^b,c   Cristini, Christelle ^c   Schott, Anne Marie ^d   Blain, Hubert ^e   Beauchet, Olivier ^f   Cesari, Matteo ^a,b   Lauwers Cances, Valérie ^c  

^a TOULOUSE UNIVERSITY HOSPITAL   (France)

^b Faculté de Médecine Centre Hospitalo universitaire   (France)

^c UNIVERSITÉ PAUL SABATIER   (France)

^d University of Lyon Claude Bernard   (France)

^e MONTPELLIER UNIVERSITY HOSPITAL   (France)

^f ANGERS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY COMPOSITION; BODY FAT DISTRIBUTION; BODY MASS; COHORT ANALYSIS; DUAL ENERGY X RAY ABSORPTIOMETRY; FAT MASS; FEMALE; FOLLOW UP; HIP CIRCUMFERENCE; HUMAN; LEAN BODY WEIGHT; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MORTALITY; MUSCLE MASS; PROSPECTIVE STUDY; RISK ASSESSMENT; WAIST CIRCUMFERENCE; WAIST HIP RATIO; ADIPOSE TISSUE; BODY HEIGHT; BODY WEIGHT; DAILY LIFE ACTIVITY; METABOLISM; OBESITY; PHOTON ABSORPTIOMETRY; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; VERY ELDERLY;

ABSORPTIOMETRY, PHOTON; ACTIVITIES OF DAILY LIVING; ADIPOSE TISSUE; AGED; AGED, 80 AND OVER; BODY COMPOSITION; BODY HEIGHT; BODY MASS INDEX; BODY WEIGHT; FEMALE; FOLLOW-UP STUDIES; HUMANS; LONGITUDINAL STUDIES; OBESITY; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS; WAIST CIRCUMFERENCE;

EID: 84908147011     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.114.086728     Document Type: Article

References (50)

1. Adams KF, Schatzkin A, Harris TB, Kipnis V, Mouw T, Ballard-Barbash R, Hollenbeck A, Leitzmann MF. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med 2006;355:763-78.
2. Flegal KM, Graubard BI, Williamson DF, Gail MH. Excess deaths associated with underweight, overweight, and obesity. JAMA 2005;293:1861-7.
3. Dolan CM, Kraemer H, Browner W, Ensrud K, Kelsey JL. Associations between body composition, anthropometry, and mortality in women aged 65 years and older. Am J Public Health 2007;97:913-8.
4. Janssen I, Katzmarzyk PT, Ross R. Body mass index is inversely related to mortality in older people after adjustment for waist circumference. J Am Geriatr Soc 2005;53:2112-8.
5. Flicker L, McCaul KA, Hankey GJ, Jamrozik K, Brown WJ, Byles JE, Almeida OP. Body mass index and survival in men and women aged 70 to 75. J Am Geriatr Soc 2010;58:234-41.
6. Auyeung TW, Lee JS, Leung J, Kwok T, Leung PC, Woo J. Survival in older men may benefit from being slightly overweight and centrally obese-a 5-year follow-up study in 4,000 older adults using DXA. J Gerontol A Biol Sci Med Sci 2010;65:99-104.
7. McAuley P, Pittsley J, Myers J, Abella J, Froelicher VF. Fitness and fatness as mortality predictors in healthy older men: the veterans exercise testing study. J Gerontol A Biol Sci Med Sci 2009;64:695-9.
8. Kulminski AM, Arbeev KG, Kulminskaya IV, Ukraintseva SV, Land K, Akushevich I, Yashin AI. Body mass index and nine-year mortality in disabled and nondisabled older U.S. individuals. J Am Geriatr Soc 2008;56:105-10.
9. Beleigoli AM, Boersma E, Diniz Mde F, Lima-Costa MF, Ribeiro AL. Overweight and class I obesity are associated with lower 10-year risk of mortality in Brazilian older adults: the Bambui cohort study of ageing. PLoS ONE 2012;7:e52111.
10. Locher JL, Roth DL, Ritchie CS, Cox K, Sawyer P, Bodner EV, Allman RM. Body mass index, weight loss, and mortality in community-dwelling older adults. J Gerontol A Biol Sci Med Sci 2007;62:1389-92.
11. Corrada MM, Kawas CH, Mozaffar F, Paganini-Hill A. Association of body mass index and weight change with all-cause mortality in the elderly. Am J Epidemiol 2006;163:938-49.
12. Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 2013;309:71-82.
13. Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity. JAMA 2003;289:187-93.
14. Chapman IM. Obesity paradox during aging. Interdiscip Top Gerontol 2010;37:20-36.
15. Dixon JB, Lambert GW. The obesity paradox - a reality that requires explanation and clinical interpretation. Atherosclerosis 2013;226:47-8.
16. Lavie CJ, Milani RV, Ventura HO. Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J Am Coll Cardiol 2009;53:1925-32.
17. Uretsky S, Messerli FH, Bangalore S, Champion A, Cooper-Dehoff RM, Zhou Q, Pepine CJ. Obesity paradox in patients with hypertension and coronary artery disease. Am J Med 2007;120:863-70.
18. Clark AL, Fonarow GC, Horwich TB. Waist circumference, body mass index, and survival in systolic heart failure: the obesity paradox revisited. J Card Fail 2011;17:374-80.
19. Badheka AO, Rathod A, Kizilbash MA, Garg N, Mohamad T, Afonso L, Jacob S. Influence of obesity on outcomes in atrial fibrillation: yet another obesity paradox. Am J Med 2010;123:646-51.
20. Agarwal R, Bills JE, Light RP. Diagnosing obesity by body mass index in chronic kidney disease: an explanation for the "obesity paradox?". Hypertension 2010;56:893-900.
21. Kim BJ, Lee SH, Jung KH, Yu KH, Lee BC, Roh JK. Dynamics of obesity paradox after stroke, related to time from onset, age, and causes of death. Neurology 2012;79:856-63.
22. Gallagher D, Visser M, Sepulveda D, Pierson RN, Harris T, Heymsfield SB. How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups? Am J Epidemiol 1996;143:228-39.
23. Ahima RS, Lazar MA. Physiology. The health risk of obesity-better metrics imperative. Science 2013;341:856-8.
24. Micozzi MS, Harris TM. Age variations in the relation of body mass indices to estimates of body fat and muscle mass. Am J Phys Anthropol 1990;81:375-9.
25. De Lorenzo A, Bianchi A, Maroni P, Iannarelli A, Di Daniele N, Iacopino L, Di Renzo L. Adiposity rather than BMI determines metabolic risk. Int J Cardiol 2013;166:111-7.
26. Romero-Corral A, Lopez-Jimenez F, Sierra-Johnson J, Somers VK. Differentiating between body fat and lean mass-how should we measure obesity? Nat Clin Pract Endocrinol Metab 2008;4:322-3.
27. Folsom AR, Kushi LH, Anderson KE, Mink PJ, Olson JE, Hong CP, Sellers TA, Lazovich D, Prineas RJ. Associations of general and abdominal obesity with multiple health outcomes in older women: the Iowa Women's Health Study. Arch Intern Med 2000;160:2117-28.
28. Wannamethee SG, Shaper AG, Lennon L, Whincup PH. Decreased muscle mass and increased central adiposity are independently related to mortality in older men. Am J Clin Nutr 2007;86:1339-46.
29. Kuk JL, Ardern CI. Influence of age on the association between various measures of obesity and all-cause mortality. J Am Geriatr Soc 2009;57:2077-84.
30. Han SS, Kim KW, Kim KI, Na KY, Chae DW, Kim S, Chin HJ. Lean mass index: a better predictor of mortality than body mass index in elderly Asians. J Am Geriatr Soc 2010;58:312-7.
31. Newman AB, Kupelian V, Visser M, Simonsick EM, Goodpaster BH, Kritchevsky SB, Tylavsky FA, Rubin SM, Harris TB. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci 2006;61:72-7.
32. Cesari M, Pahor M, Lauretani F, Zamboni V, Bandinelli S, Bernabei R, Guralnik JM, Ferrucci L. Skeletal muscle and mortality results from the InCHIANTI Study. J Gerontol A Biol Sci Med Sci 2009;64:377-84.
33. Chang SH, Beason TS, Hunleth JM, Colditz GA. A systematic review of body fat distribution and mortality in older people. Maturitas 2012;72:175-91.
34. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000;894:i-xii, 1-253.
35. Dargent-Molina P, Favier F, Grandjean H, Baudoin C, Schott AM, Hausherr E, Meunier PJ, Bréart G. Fall-related factors and risk of hip fracture: the EPIDOS prospective study. Lancet 1996;348:145-9.
36. Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969;9:179-86.
37. Desquilbet L, Mariotti F. Dose-response analyses using restricted cubic spline functions in public health research. Stat Med 2010;29:1037-57.
38. Royston P, Altman D. Regression using fractional polynomials of continuous covariates: parsimonious parametric modelling. Appl Stat 1994;43:429-67.
39. Harrell FE. Regression modeling strategies with applications to linear models, logistic regression and survival analysis. New York, NY: Springer-Verlag Inc, 2001.
40. Stevens J, Cai J, Pamuk ER, Williamson DF, Thun MJ, Wood JL. The effect of age on the association between body-mass index and mortality. N Engl J Med 1998;338:1-7.
41. Zheng W, McLerran DF, Rolland B, Zhang X, Inoue M, Matsuo K, He J, Gupta PC, Ramadas K, Tsugane S, et al. Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med 2011;364:719-29.
42. Doehner W, Clark A, Anker SD. The obesity paradox: weighing the benefit. Eur Heart J 2010;31:146-8.
43. Lopez-Jimenez F. Speakable and unspeakable facts about BMI and mortality. Lancet 2009;373:1055-6.
44. St-Onge MP, Gallagher D. Body composition changes with aging: the cause or the result of alterations in metabolic rate and macronutrient oxidation? Nutrition 2010;26:152-5.
45. Bunout D, de la Maza MP, Barrera G, Leiva L, Hirsch S. Association between sarcopenia and mortality in healthy older people. Australas J Ageing 2011;30:89-92.
46. Ferrucci L, Schrack JA, Knuth ND, Simonsick EM. Aging and the energetic cost of life. J Am Geriatr Soc 2012;60:1768-9.
47. Ruggiero C, Metter EJ, Melenovsky V, Cherubini A, Najjar SS, Ble A, Senin U, Longo DL, Ferrucci L. High basal metabolic rate is a risk factor for mortality: the Baltimore Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci 2008;63:698-706.
48. Schrack JA, Simonsick EM, Ferrucci L. The energetic pathway to mobility loss: an emerging new framework for longitudinal studies on aging. J Am Geriatr Soc 2010;58(suppl 2):S329-36.
49. Priede IG. Natural selection for energetic efficiency and the relationship between activity level and mortality. Nature 1977;267:610-1.
50. Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, Qizilbash N, Collins R, Peto R. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet 2009;373:1083-96.