The multi-center randomized controlled trial (RCT) published by the journal of the american medical association (JAMA) on the effect of periodontal therapy on glycated hemoglobin (hba1c) has fundamental problems

Journal of Evidence-Based Dental Practice

Volumn 14, Issue 3, 2014, Pages 127-132

  Borgnakke, Wenche S ^a   Chapple, Iain L C ^b   Genco, Robert J ^c   Armitage, Gary ^c   Bartold, P Mark ^c   D'Aiuto, Francesco ^c   Eke, Paul I ^c   Giannobile, William V ^c   Kocher, Thomas ^c   Kornman, Kenneth S ^c   Lang, Niklaus P ^c   Madianos, Phoebus N ^c   Murakami, Shinya ^c   Nishimura, Fusanori ^c   Offenbacher, Steven ^c   Preshaw, Philip M ^c   Rahman, Amin Ur ^c   Sanz, Mariano ^c   Slots, Jørgen ^c   Tonetti, Maurizio S ^c   Van Dyke, Thomas E ^c   more..

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATED HEMOGLOBIN;

BLOOD; CHRONIC PERIODONTITIS; DIABETES COMPLICATIONS; FEMALE; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVENTIVE DENTISTRY;

CHRONIC PERIODONTITIS; DENTAL SCALING; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; ROOT PLANING;

EID: 84908099947     PISSN: 15323382     EISSN: 15323390     Source Type: Journal    
DOI: 10.1016/j.jebdp.2014.04.017     Document Type: Note

References (19)

1. S.P. Engebretson, L.G. Hyman, B.S. Michalowicz, E.R. Schoenfeld, M.C. Gelato, and W. Hou The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: a randomized clinical trial J Am Med Assoc 310 2013 2523 2532
2. S.J. Janket, A. Wightman, A.E. Baird, T.E. Van Dyke, and J.A. Jones Does periodontal treatment improve glycemic control in diabetic patients? A meta-analysis of intervention studies J Dent Res 84 2005 1154 1159
3. L. Darré, J.N. Vergnes, P. Gourdy, and M. Sixou Efficacy of periodontal treatment on glycaemic control in diabetic patients: a meta-analysis of interventional studies Diabetes Metab 34 2008 497 506
4. W.J. Teeuw, V.E. Gerdes, and B.G. Loos Effect of periodontal treatment on glycemic control of diabetic patients: a systematic review and meta-analysis Diabetes Care 33 2010 421 427
5. T.C. Simpson, I. Needleman, S.H. Wild, D.R. Moles, and E.J. Mills Treatment of periodontal disease for glycaemic control in people with diabetes Cochrane Database Syst Rev 2010 CD004714
6. F. Sgolastra, M. Severino, D. Pietropaoli, R. Gatto, and A. Monaco Effectiveness of periodontal treatment to improve metabolic control in patients with chronic periodontitis and type 2 diabetes: a meta-analysis of randomized clinical trials J Periodontol 84 2013 958 973
7. S. Engebretson, and T. Kocher Evidence that periodontal treatment improves diabetes outcomes: a systematic review and meta-analysis J Clin Periodontol 40 suppl 14 2013 S153 S163
8. 1c: a meta-analysis of randomized controlled trials Aust Dent J 58 2013 350 357
9. 1c) levels in subjects with type 2 diabetes and chronic periodontitis Contemp Clin Trials 36 2013 515 526
10. American Diabetes Association Standards of medical care in diabetes-2014 Diabetes Care 37 suppl 1 2014 S14 S80
11. N.P. Lang, W.C. Tan, M.A. Krahenmann, and M. Zwahlen A systematic review of the effects of full-mouth debridement with and without antiseptics in patients with chronic periodontitis J Clin Periodontol 35 2008 8 21
12. C.M. Cobb Non-surgical pocket therapy: mechanical Ann Periodontol 1 1996 443 490
13. C.M. Cobb Clinical significance of non-surgical periodontal therapy: an evidence-based perspective of scaling and root planing J Clin Periodontol 29 suppl 2 2002 6 16
14. G.A. Van der Weijden, and M.F. Timmerman A systematic review on the clinical efficacy of subgingival debridement in the treatment of chronic periodontitis J Clin Periodontol 29 suppl 3 2002 55 71 discussion 90-91
15. Y. Munenaga, T. Yamashina, J. Tanaka, and F. Nishimura Improvement of glycated hemoglobin in Japanese subjects with type 2 diabetes by resolution of periodontal inflammation using adjunct topical antibiotics: results from the Hiroshima Study Diabetes Res Clin Pract 100 2013 53 60
16. G.D. Slade, E.M. Ghezzi, G. Heiss, J.D. Beck, E. Riche, and S. Offenbacher Relationship between periodontal disease and C-reactive protein among adults in the Atherosclerosis Risk in Communities study Arch Intern Med 163 2003 1172 1179
17. S. Offenbacher, J.D. Beck, K. Moss, L. Mendoza, D.W. Paquette, and D.A. Barrow Results from the Periodontitis and Vascular Events (PAVE) Study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease J Periodontol 80 2009 190 201
18. G.C. Armitage Effect of periodontal therapy on general health - is there a missing component in the design of these clinical trials? J Clin Periodontol 35 2008 1011 1012
19. S. Offenbacher, J. Beck On behalf of the Maternal Oral Therapy to Reduce Obstetric Risk (MOTOR) Investigators Effects of periodontal therapy on rate of preterm delivery: a randomized controlled trial [Letter] Obstet Gynecol 115 2010 386