Mechanisms and management of functional abdominal pain

Journal of the Royal Society of Medicine

Volumn 107, Issue 9, 2014, Pages 347-354

  Farmer, Adam d ^a   Aziz, Qasim ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

functional abdominal pain; investigation; management; pathophysiology

Indexed keywords

ABDOMINAL PAIN; FEMALE; FUNCTIONAL ABDOMINAL PAIN; HUMAN; INVESTIGATION; MALE; MANAGEMENT; PATHOPHYSIOLOGY; PSYCHOLOGICAL ASPECT; REVIEW; SPINAL CORD; SPINAL NERVE; SYNDROME;

FUNCTIONAL ABDOMINAL PAIN; INVESTIGATION; MANAGEMENT; PATHOPHYSIOLOGY;

ABDOMINAL PAIN; FEMALE; HUMANS; MALE; SPINAL CORD; SPINAL NERVES; SYNDROME;

EID: 84908090311     PISSN: 01410768     EISSN: 17581095     Source Type: Journal    
DOI: 10.1177/0141076814540880     Document Type: Review

References (36)

1. Merskey H Bogduk N. Classification of chronic pain: descriptions of chronic pain syndromes and definitions of pain terms, 2nd ed. Seattle, WA: IASP Press, 1994.
2. Collett B. Visceral pain: the importance of pain management services. Br J Pain 2013 7: 6-7.
3. Farmer AD Aziz Q. Recent advances in chronic visceral pain. Curr Opin Support Palliat Care 2008 2: 116-121.
4. Lovell RM Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol 2012 10: 712-721 e4.
5. Shivali UN Ford AC. Prevalence of functional gastrointestinal disorders among consecutive new patient referrals to a gastroenterology clinic. Frontline Gastroenterol 2014 4.: DOI: 10.1136/flgastro-2013-100426–DOI: 10.1136/flgastro-2013-100426.
6. Drossman DA. Rome III: the functional gastrointestinal disorders, 3rd ed. McLean, VA: Degnon Associates, 2006, pp. xli, 1048 p–xli, 1048 p.
7. Clouse RE Mayer EA Aziz Q. Functional abdominal pain syndrome. Gastroenterology 2006 130: 1492-1497.
8. Knowles CH Aziz Q. Basic and clinical aspects of gastrointestinal pain. Pain 2009 141: 191-209.
9. Wilder-Smith CH Robert-Yap J. Abnormal endogenous pain modulation and somatic and visceral hypersensitivity in female patients with irritable bowel syndrome. World J Gastroenterol 2007 13: 3699-3704.
10. Matthews PJ Aziz Q. Functional abdominal pain. Postgrad Med J 2005 81: 448-455.
11. Farmer AD Coen SJ Kano M. Psychophysiological responses to pain identify reproducible human clusters. Pain 2013 154: 2266-2276.
12. Farmer AD Coen SJ Kano M. Psychophysiological responses to visceral and somatic pain in functional chest pain identify clinically relevant pain clusters. Neurogastroenterol Motil 2014 26: 139-148.
13. Aziz Q Furlong PL Barlow J. Topographic mapping of cortical potentials evoked by distension of the human proximal and distal oesophagus. Electroencephalogr Clin Neurophysiol 1995 96: 219-228.
14. Spiller R Lam C. An update on post-infectious irritable bowel syndrome: role of genetics, immune activation, serotonin and altered microbiome. J Neurogastroenterol Motil 2012 18: 258-268.
15. Bhuiyan MR Majumder TK Raihan AA Roy PK Farha N Kamal M. Histopathological alterations in post-infectious irritable bowel syndrome in Bangladeshi population. Mymensingh Med J 2010 19: 275-281.
16. Gwee KA. Postinfectious irritable bowel syndrome. Curr Treat Options Gastroenterol 2001 4: 287-291.
17. Sarkar S Aziz Q Woolf CJ Hobson AR Thompson DG. Contribution of central sensitisation to the development of non-cardiac chest pain. Lancet 2000 356: 1154-1159.
18. Munakata J Naliboff B Harraf F. Repetitive sigmoid stimulation induces rectal hyperalgesia in patients with irritable bowel syndrome. Gastroenterology 1997 112: 55-63.
19. Willert RP Woolf CJ Hobson AR Delaney C Thompson DG Aziz Q. The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor. Gastroenterology 2004 126: 683-692.
20. Walker LS Sherman AL Bruehl S Garber J Smith CA. Functional abdominal pain patient subtypes in childhood predict functional gastrointestinal disorders with chronic pain and psychiatric comorbidities in adolescence and adulthood. Pain 2012 153: 1798-1806.
21. Wilder-Smith CH Schindler D Lovblad K Redmond SM Nirkko A. Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls. Gut 2004 53: 1595-1601.
22. Nozu T Kudaira M. Altered rectal sensory response induced by balloon distention in patients with functional abdominal pain syndrome. Biopsychosoc Med 2009 3: 13-13.
23. Wilder-Smith CH. The balancing act: endogenous modulation of pain in functional gastrointestinal disorders. Gut 2011 60: 1589-1599.
24. Ruepert L Quartero AO de Wit NJ van der Heijden GJ Rubin G Muris JW. Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome. Cochrane Database Syst Rev 2011 10(8): 3460-3460.
25. Dharmshaktu P Tayal V Kalra BS. Efficacy of antidepressants as analgesics: a review. J Clin Pharmacol 2012 52: 6-17.
26. Moore RA Derry S Aldington D Cole P Wiffen PJ. Amitriptyline for neuropathic pain and fibromyalgia in adults. Cochrane Database Syst Rev 2012 12: 8242-8242.
27. Pergolizzi JV Jr. Raffa RB Taylor R Jr. Rodriguez G Nalamachu S Langley P. A review of duloxetine 60 mg once-daily dosing for the management of diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain due to chronic osteoarthritis pain and low back pain. Pain Pract 2013 13: 239-252.
28. Arnold LM Pritchett YL D'Souza DN Kajdasz DK Iyengar S Wernicke JF. Duloxetine for the treatment of fibromyalgia in women: pooled results from two randomized, placebo-controlled clinical trials. J Women's Health 2007 16: 1145-1156.
29. Russell IJ Mease PJ Smith TR. Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. Pain 2008 136: 432-444.
30. Ford AC Talley NJ Schoenfeld PS Quigley EM Moayyedi P. Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis. Gut 2009 58: 367-78.
31. Palsson OS Whitehead WE. Psychological treatments in functional gastrointestinal disorders: a primer for the gastroenterologist. Clin Gastroenterol Hepatol 2013 11: 208-216; quiz e22–e23.
32. Grunkemeier DM Cassara JE Dalton CB Drossman DA. The narcotic bowel syndrome: clinical features, pathophysiology, and management. Clin Gastroenterol Hepatol 2007 5: 1126-1139; quiz 1-2.
33. Farmer AD Ferdinand E Aziz Q. Opioids and the gastrointestinal tract–a case of narcotic bowel syndrome and literature review. J Neurogastroenterol Motil 2013 19: 94-98.
34. Chen L Mao J. Update on neuropathic pain treatment: ion channel blockers and gabapentinoids. Curr Pain Headache Rep 2013 17: 359-359.
35. Lee KJ Kim JH Cho SW. Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome. Alimentary Pharmacol Ther 2005 22: 981-988.
36. Houghton LA Fell C Whorwell PJ Jones I Sudworth DP Gale JD. Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome. Gut 2007 56: 1218-1225.